BGC0000279: Xantholipin biosynthetic gene cluster from Streptomyces flavogriseus
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Location: 1 - 52,255 nt. (total: 52,255 nt).
This entry is originally from NCBI GenBank GQ421798.1.

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Gene details
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General
Compounds
Genes
History
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0000279
Short description Xantholipin biosynthetic gene cluster from Streptomyces flavogriseus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: GQ421798.1
Compounds
  • Xantholipin
Species Streptomyces flavogriseus [taxonomy]
References
Chemical products information
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Xantholipin
Molecular Formula C72H2NO10
Chemical database entries NPAtlas  
List of genes involved in compound(s) production
Identifiers Position Product Functions Extra
  • ADE22275.1
  • xanY1
1 1419 - putative adenosylhomocysteinase
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  • ADE22276.1
  • xanY2
1397 2299 - 5,10-methylenetetrahydrofolate reductase
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  • ADE22277.1
  • xanY3
2305 5802 - methionine synthase
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  • ADE22278.1
  • xanY4
5799 6791 - carbohydrate kinase
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  • ADE22279.1
  • xanY5
6817 8037 - S-adenosylmethionine synthetase
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  • ADE22280.1
  • xanO1
8146 8583 - putative oxygenase
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  • ADE22281.1
  • xanS1
8580 9803 - putative dehydrogenase
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  • ADE22282.1
  • xanJ
9867 10595 + hypothetical protein
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  • ADE22283.1
  • xanP
10592 12211 + putative spore coat protein
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  • ADE22284.1
  • xanG
12379 13554 + putative inactive gylcosyltransferase
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  • ADE22285.1
  • xanA
13542 15386 + putative asparagine synthase
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  • ADE22286.1
  • xanR1
15392 16075 + putative transcriptional regulator
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  • ADE22287.1
  • xanO2
16114 17316 + putative cytochrome P450 hydroxylase
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  • ADE22288.1
  • xanK
17333 17602 + putative 3Fe-S ferredoxin
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  • ADE22289.1
  • xanU
17599 19728 + putative antibiotic transporter
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  • ADE22290.1
  • xanO3
19908 21086 + FAD-binding monooxygenase
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  • ADE22291.1
  • xanL
21147 21707 - putative lactoylglutathione lyase
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  • ADE22292.1
  • xanH
22057 23472 + putative non-heme halogenase
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  • ADE22293.1
  • xanQ
23469 25070 + putative peptide transporter
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  • ADE22294.1
  • xanM1
25067 26086 + putative O-methyltransferase
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  • ADE22295.1
  • xanZ1
26651 27508 + putative F420-dependent reductase
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  • ADE22296.1
  • xanN
27593 28888 - putative integral membrane ion antiporter
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  • ADE22297.1
  • xanW
28985 29473 - hypothetical protein
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  • ADE22298.1
  • xanR2
29600 30061 + putative transcriptional regulator
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  • ADE22299.1
  • xanM2
30083 31105 - putative O-methyltransferase
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  • ADE22300.1
  • xanO4
31120 32742 - putative FAD-binding monooxygenase
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  • ADE22301.1
  • xanM3
33084 34118 + putative methyltransferase
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  • ADE22302.1
  • xanO5
34203 35798 + putative FAD-binding monooxygenase
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  • ADE22303.1
  • xanS2
35868 36554 + putative short-chain dehydrogenase/reductase SDR
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  • ADE22304.1
  • xanZ2
36759 37667 - putative oxidoreductase
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  • ADE22305.1
  • xanR3
37715 38722 + putative transcriptional regulator
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  • ADE22306.1
  • xanB1
38844 40187 - biotin carboxylase
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  • ADE22307.1
  • xanB2
40190 40714 - biotin carboxyl carrier protein
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  • ADE22308.1
  • xanB3
40774 42468 - carboxyl transferase
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  • ADE22309.1
  • xanO6
42546 42857 - putative monooxygenase
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  • ADE22310.1
  • xanO7
42847 43194 - putative monooxygenase
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  • ADE22311.1
  • xanZ3
43194 43946 - putative 3-oxoacyl-ACP reductase
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  • ADE22312.1
  • xanO8
43970 44431 - putative monooxygenase
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  • ADE22313.1
  • xanC1
44442 44909 - putative polyketide cyclase
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  • ADE22314.1
  • xanE
45017 46303 - putative polyketide beta-ketoacyl synthase beta
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  • ADE22315.1
  • xanF
46306 47583 - putative polyketide beta-ketoacyl synthase alpha
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  • ADE22316.1
  • xanC2
47580 48014 - putative polyketide cyclase
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  • ADE22317.1
  • xanT
48198 48584 + CurD-like protein
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  • ADE22318.1
  • xanO9
48596 50014 + oxidase-like protein
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  • ADE22319.1
  • xanO10
50067 50513 - putative monooxygenase
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  • ADE22320.1
  • xanV
50528 50908 - hypothetical protein
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  • ADE22321.1
  • xanZ4
50908 51663 - 3-oxoacyl-ACP reductase
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  • ADE22322.1
  • xanD
51660 51920 - acyl carrier protein
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  • ADE22323.1
  • xanC3
51917 52255 - putative polyketide cyclase
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Annotation changelog
MIBiG version Notes
2.0
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
Detailed domain annotation
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