LOCUS       BGC0000282              2613 bp    DNA     linear   BCT 07-OCT-2016
DEFINITION  Streptomyces griseus subsp. griseus NBRC 13350 DNA, complete genome.
ACCESSION   BGC0000282
VERSION     BGC0000282
KEYWORDS    .
SOURCE      Streptomyces griseus subsp. griseus NBRC 13350
  ORGANISM  Streptomyces griseus subsp. griseus NBRC 13350
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     On or before Apr 8, 2008 this sequence version replaced AB365454.1,
            AB425192.1.
            The complete and fully annotated sequences are also available at
            http://park.itc.u-tokyo.ac.jp/hakko/genome/
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 13:19:07
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2613
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1017)
                     /codon_start=1
                     /gene="srsC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1161:oxidoreductase (Score: 365.4; E-value: 5.1e-111)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SGR_470"
                     /product="monooxygenase"
                     /protein_id="BAG17299.1"
                     /transl_table=11
                     /translation="MIDVLVVGGGPAGLAAAIRAAATGLEAVVVEPRTSPVDKACGEGI
                     MPGGVAALRDLGVRVRGRELRGIRYTDGRRSAEAAFRGDPGAGVRRTELHTALHERAAA
                     LGVRVVAAKAGEVRQDEHTVTAAGLTARWLVAADGLHSPLRRSLGLDRPVAGPGRYGLR
                     RHYPLAPWTDHVEVHWSRHGEAYVTPVGEHLVGVAVLSRDRHPYDRHLAAFPALAARLA
                     DSAGATPVRGAGPLRQRARGLRAGRVLLAGDAAGYVDALTGEGIALAVATATAAVDCLR
                     AGRPEDYPRRWTRATRRHRLLTAALLGAAGHPSSRRLIVSAAHRAPVLFRTAVHALQ"
     protocluster    1..2613
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[1560:2613]"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1561..2613
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     cand_cluster    1..2613
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..2613
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000282"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..2613
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..1017)
                     /gene="srsC"
                     /locus_tag="SGR_470"
     gene            complement(1014..1547)
                     /gene="srsB"
                     /locus_tag="SGR_471"
     CDS             complement(1014..1547)
                     /codon_start=1
                     /gene="srsB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1150:isoprenylcysteine carboxyl methyltransferase
                     (Score: 247.2; E-value: 1.2e-75)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SGR_471"
                     /product="methyltransferase"
                     /protein_id="BAG17300.1"
                     /transl_table=11
                     /translation="MTSTWYTLLVLAVAAERLAELVVARRNTRWSLARGGVESGRGHYP
                     AMVALHTGLLLGCLAEVRFAERPFPAVLGWTMAGVVVASQALRWWCIRTLGPRWNTRVI
                     VVPGLPRVTGGPYRWLSHPNYVAVAAEGIALPLVHGAWVTALVFTALNAALMVVRIRCE
                     DGALARLPAADAPA"
     gene            complement(1561..2613)
                     /gene="srsA"
                     /locus_tag="SGR_472"
     CDS             complement(1561..2613)
                     /codon_start=1
                     /experiment="gene cloning and expression"
                     /gene="srsA"
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:chalcone and stilbene synthase domain protein
                     (Score: 426; E-value: 1.4e-129)"
                     /gene_kind="biosynthetic"
                     /locus_tag="SGR_472"
                     /product="type-III PKS"
                     /protein_id="BAG17301.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 3e-23, bitscore:
                     70.1, seeds: 21, tool: rule-based-clusters)"
                     /sec_met_domain="Chal_sti_synt_C (E-value: 1.5e-22,
                     bitscore: 68.1, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRIAAVHGALPPHRHTQREVTDLVARTCLPPGADRRVLDRLHEN
                     ARVRARHTVLPLDGYRALDGFGATNDVFIRSAVDLGARAVRGALRSAGLRPTDVDLLMF
                     TSVTGIAAPSVDARLVTRLGMRSDVKRLPVFGLGCVAGAAGTARLHDYLLGRPDDVAVL
                     LSVELCSLTFQRHDASPANLVATALFGDGAAALVALGGRRAVSGPEIVATRSRMYPDTE
                     HVMGWDVGSTGFRVVLDPAVPDVVRQYLADDVREFLDEHGLKPKDVAHWVCHPGGPKVL
                     EAVTEVLDLPDGALDVTWRSLADVGNLSSSSVLHVLRDTIEQRRPEPGTPGLLLAMGPG
                     FCCELVLLRW"
ORIGIN
        1 tcactggagc gcgtggaccg cggtgcggaa gaggacgggc gcccggtggg cggcggagac
       61 gatcagccgc cgggacgacg ggtggcccgc ggcgcccagc agggcggcgg tgagcagccg
      121 gtggcgccgg gtggcccggg tccaccgccg ggggtagtcc tcgggccgcc cggccctcag
      181 gcagtcgacg gcggccgtcg cggtggcgac ggcgagggcg atgccctccc cggtcagggc
      241 gtccacgtag cccgcggcgt cgccggccag gaggacgcgc ccggccctca ggccccgcgc
      301 gcgctgccgc agcggcccgg ccccgcgcac gggggtggcg cccgcgctgt ccgcgagccg
      361 ggccgcgagg gcggggaagg cggccagatg ccggtcgtag gggtggcggt cccggctcag
      421 gacggccacc cccaccaggt gctcgccgac cggggtcacg tacgcctcgc cgtgccggga
      481 ccagtgcacc tcgacgtggt ccgtccaggg ggcgagcggg tagtggcggc gcaggccgta
      541 gcgcccgggt ccggcgacgg gccggtcgag gcccagggag cggcgcagcg gcgagtgcag
      601 cccgtcggcg gcgacgagcc agcgcgcggt gagtccggcg gcggtgacgg tgtgctcgtc
      661 ctgccggacc tcccccgcct tcgcggcgac gacgcggacg ccgagggcgg cggcccgctc
      721 gtgcagggcg gtgtggagtt cggtgcggcg gacgcccgcg ccggggtcgc cccggaaggc
      781 cgcctccgcg ctgcgccggc cgtcggtgta gcggatgccg cgcagttcac ggcccctcac
      841 ccgcacgccg aggtcacgca gggccgcgac accgccgggc atgatgccct cgccgcaggc
      901 cttgtccacg gggctggtgc gcggctcgac caccaccgct tccaggcctg tcgcggcggc
      961 gcggatcgcg gcggccagtc cggccggtcc gccgccgacg accaggacgt cgatcacgcg
     1021 ggcgcgtccg cggccgggag gcgggcgagc gccccgtcct cgcagcggat ccgcaccacc
     1081 atgagcgcgg cgttgagggc ggtgaagacg agggcggtca cccaggcccc gtggaccagg
     1141 ggcagcgcga tgccttcggc ggcgacggcg acgtagttgg ggtggctcag ccaccggtag
     1201 gggccgccgg tgacccgggg caggccgggg acgacgatga cccgggtgtt ccagcggggg
     1261 ccgagcgtgc ggatgcacca ccagcgcagc gcctgcgagg cgacgacgac gccggccatc
     1321 gtccagccga gcacggccgg gaagggccgt tcggcgaacc ggacctccgc caggcagccg
     1381 agcaggagcc cggtgtggag cgcgaccatc gccggatagt gcccgcggcc cgattcgacg
     1441 ccgccccggg cgaggctcca gcgggtgttg cggcgggcca cgacgagttc ggcgaggcgc
     1501 tcggccgcga cggccagcac caggagggtg taccaggtcg aggtcatggg tctctccttc
     1561 ctaccagcgc agcagcacca gttcgcagca gaatcccggg cccatggcca gcagcagtcc
     1621 gggggtgccg ggctcggggc ggcgctgctc gatggtgtcc cgcaggacgt gcaggaccga
     1681 ggacgaggac aggttgccga cgtcggcaag cgagcgccag gtgacgtcga gcgcgccgtc
     1741 gggcagatcg aggacctcgg tgacggcctc caggaccttg gggccgcccg ggtggcacac
     1801 ccagtgggcg acgtccttcg gcttgagtcc gtgctcgtcg aggaactccc gtacgtcgtc
     1861 ggcgaggtac tggcgcacga cgtcgggcac ggccggatcg aggacgacgc ggaacccggt
     1921 ggagccgacg tcccacccca tgacgtgctc ggtgtccggg tacatccggc tgcgggtggc
     1981 cacgatctcg gggccggaga cggcccgccg cccgccgagg gcgaccaggg cggccgctcc
     2041 gtcgccgaac agcgcggtcg ccacgagatt ggcgggcgag gcgtcgtggc gctggaaggt
     2101 gagggagcag agctcgaccg acaggagcac ggccacgtcg tcggggcggc cgaggaggta
     2161 gtcgtgcagc cgggccgtcc cggccgctcc ggcgacgcag cccagcccga agacgggcag
     2221 ccgcttgacg tccgagcgca tgccgaggcg ggtcacgagc cgggcgtcga cggagggggc
     2281 ggcgatgccg gtgaccgagg tgaacatcag caggtccaca tcggtgggcc gcagccccgc
     2341 cgatcgcagc gcgccgcgta cggcccgggc gccgaggtcc acggcggagc ggatgaacac
     2401 gtcgttggtc gcgccgaagc cgtcgagtgc gcggtagccg tccaggggca gcacggtgtg
     2461 ccgggcgcgg acccgggcgt tctcgtggag ccggtccagg acacggcggt cggctccggg
     2521 cggcaggcag gtgcgggcca ccaggtcggt gacctcgcgc tgggtgtggc ggtggggcgg
     2581 cagagccccg tggaccgcgg cgatgcgggt cat
//
