LOCUS       BGC0000287             13011 bp    DNA     linear   BCT 31-JAN-2014
DEFINITION  Pseudomonas aeruginosa PAO1, complete genome.
ACCESSION   BGC0000287
VERSION     BGC0000287
KEYWORDS    .
SOURCE      Pseudomonas aeruginosa PAO1
  ORGANISM  Pseudomonas aeruginosa PAO1
            Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Pseudomonas.
COMMENT     On or before Jul 7, 2006 this sequence version replaced AE004440.1,
            AE004441.1, AE004442.1, AE004443.1, AE004444.1, AE004445.1,
            AE004446.1, AE004447.1, AE004448.1, AE004449.1, AE004450.1,
            AE004451.1, AE004452.1, AE004453.1, AE004454.1, AE004455.1,
            AE004456.1, AE004457.1, AE004458.1, AE004459.1, AE004460.1,
            AE004461.1, AE004462.1, AE004463.1, AE004464.1, AE004465.1,
            AE004466.1, AE004467.1, AE004468.1, AE004469.1, AE004470.1,
            AE004471.1, AE004472.1, AE004473.1, AE004474.1, AE004475.1,
            AE004476.1, AE004477.1, AE004478.1, AE004479.1, AE004480.1,
            AE004481.1, AE004482.1, AE004483.1, AE004484.1, AE004485.1,
            AE004486.1, AE004487.1, AE004488.1, AE004489.1, AE004490.1,
            AE004491.1, AE004492.1, AE004493.1, AE004494.1, AE004495.1,
            AE004496.1, AE004497.1, AE004498.1, AE004499.1, AE004500.1,
            AE004501.1, AE004502.1, AE004503.1, AE004504.1, AE004505.1,
            AE004506.1, AE004507.1, AE004508.1, AE004509.1, AE004510.1,
            AE004511.1, AE004512.1, AE004513.1, AE004514.1, AE004515.1,
            AE004516.1, AE004517.1, AE004518.1, AE004519.1, AE004520.1,
            AE004521.1, AE004522.1, AE004523.1, AE004524.1, AE004525.1,
            AE004526.1, AE004527.1, AE004528.1, AE004529.1, AE004530.1,
            AE004531.1, AE004532.1, AE004533.1, AE004534.1, AE004535.1,
            AE004536.1, AE004537.1, AE004538.1, AE004539.1, AE004540.1,
            AE004541.1, AE004542.1, AE004543.1, AE004544.1, AE004545.1,
            AE004546.1, AE004547.1, AE004548.1, AE004549.1, AE004550.1,
            AE004551.1, AE004552.1, AE004553.1, AE004554.1, AE004555.1,
            AE004556.1, AE004557.1, AE004558.1, AE004559.1, AE004560.1,
            AE004561.1, AE004562.1, AE004563.1, AE004564.1, AE004565.1,
            AE004566.1, AE004567.1, AE004568.1, AE004569.1, AE004570.1,
            AE004571.1, AE004572.1, AE004573.1, AE004574.1, AE004575.1,
            AE004576.1, AE004577.1, AE004578.1, AE004579.1, AE004580.1,
            AE004581.1, AE004582.1, AE004583.1, AE004584.1, AE004585.1,
            AE004586.1, AE004587.1, AE004588.1, AE004589.1, AE004590.1,
            AE004591.1, AE004592.1, AE004593.1, AE004594.1, AE004595.1,
            AE004596.1, AE004597.1, AE004598.1, AE004599.1, AE004600.1,
            AE004601.1, AE004602.1, AE004603.1, AE004604.1, AE004605.1,
            AE004606.1, AE004607.1, AE004608.1, AE004609.1, AE004610.1,
            AE004611.1, AE004612.1, AE004613.1, AE004614.1, AE004615.1,
            AE004616.1, AE004617.1, AE004618.1, AE004619.1, AE004620.1,
            AE004621.1, AE004622.1, AE004623.1, AE004624.1, AE004625.1,
            AE004626.1, AE004627.1, AE004628.1, AE004629.1, AE004630.1,
            AE004631.1, AE004632.1, AE004633.1, AE004634.1, AE004635.1,
            AE004636.1, AE004637.1, AE004638.1, AE004639.1, AE004640.1,
            AE004641.1, AE004642.1, AE004643.1, AE004644.1, AE004645.1,
            AE004646.1, AE004647.1, AE004648.1, AE004649.1, AE004650.1,
            AE004651.1, AE004652.1, AE004653.1, AE004654.1, AE004655.1,
            AE004656.1, AE004657.1, AE004658.1, AE004659.1, AE004660.1,
            AE004661.1, AE004662.1, AE004663.1, AE004664.1, AE004665.1,
            AE004666.1, AE004667.1, AE004668.1, AE004669.1, AE004670.1,
            AE004671.1, AE004672.1, AE004673.1, AE004674.1, AE004675.1,
            AE004676.1, AE004677.1, AE004678.1, AE004679.1, AE004680.1,
            AE004681.1, AE004682.1, AE004683.1, AE004684.1, AE004685.1,
            AE004686.1, AE004687.1, AE004688.1, AE004689.1, AE004690.1,
            AE004691.1, AE004692.1, AE004693.1, AE004694.1, AE004695.1,
            AE004696.1, AE004697.1, AE004698.1, AE004699.1, AE004700.1,
            AE004701.1, AE004702.1, AE004703.1, AE004704.1, AE004705.1,
            AE004706.1, AE004707.1, AE004708.1, AE004709.1, AE004710.1,
            AE004711.1, AE004712.1, AE004713.1, AE004714.1, AE004715.1,
            AE004716.1, AE004717.1, AE004718.1, AE004719.1, AE004720.1,
            AE004721.1, AE004722.1, AE004723.1, AE004724.1, AE004725.1,
            AE004726.1, AE004727.1, AE004728.1, AE004729.1, AE004730.1,
            AE004731.1, AE004732.1, AE004733.1, AE004734.1, AE004735.1,
            AE004736.1, AE004737.1, AE004738.1, AE004739.1, AE004740.1,
            AE004741.1, AE004742.1, AE004743.1, AE004744.1, AE004745.1,
            AE004746.1, AE004747.1, AE004748.1, AE004749.1, AE004750.1,
            AE004751.1, AE004752.1, AE004753.1, AE004754.1, AE004755.1,
            AE004756.1, AE004757.1, AE004758.1, AE004759.1, AE004760.1,
            AE004761.1, AE004762.1, AE004763.1, AE004764.1, AE004765.1,
            AE004766.1, AE004767.1, AE004768.1, AE004769.1, AE004770.1,
            AE004771.1, AE004772.1, AE004773.1, AE004774.1, AE004775.1,
            AE004776.1, AE004777.1, AE004778.1, AE004779.1, AE004780.1,
            AE004781.1, AE004782.1, AE004783.1, AE004784.1, AE004785.1,
            AE004786.1, AE004787.1, AE004788.1, AE004789.1, AE004790.1,
            AE004791.1, AE004792.1, AE004793.1, AE004794.1, AE004795.1,
            AE004796.1, AE004797.1, AE004798.1, AE004799.1, AE004800.1,
            AE004801.1, AE004802.1, AE004803.1, AE004804.1, AE004805.1,
            AE004806.1, AE004807.1, AE004808.1, AE004809.1, AE004810.1,
            AE004811.1, AE004812.1, AE004813.1, AE004814.1, AE004815.1,
            AE004816.1, AE004817.1, AE004818.1, AE004819.1, AE004820.1,
            AE004821.1, AE004822.1, AE004823.1, AE004824.1, AE004825.1,
            AE004826.1, AE004827.1, AE004828.1, AE004829.1, AE004830.1,
            AE004831.1, AE004832.1, AE004833.1, AE004834.1, AE004835.1,
            AE004836.1, AE004837.1, AE004838.1, AE004839.1, AE004840.1,
            AE004841.1, AE004842.1, AE004843.1, AE004844.1, AE004845.1,
            AE004846.1, AE004847.1, AE004848.1, AE004849.1, AE004850.1,
            AE004851.1, AE004852.1, AE004853.1, AE004854.1, AE004855.1,
            AE004856.1, AE004857.1, AE004858.1, AE004859.1, AE004860.1,
            AE004861.1, AE004862.1, AE004863.1, AE004864.1, AE004865.1,
            AE004866.1, AE004867.1, AE004868.1, AE004869.1, AE004870.1,
            AE004871.1, AE004872.1, AE004873.1, AE004874.1, AE004875.1,
            AE004876.1, AE004877.1, AE004878.1, AE004879.1, AE004880.1,
            AE004881.1, AE004882.1, AE004883.1, AE004884.1, AE004885.1,
            AE004886.1, AE004887.1, AE004888.1, AE004889.1, AE004890.1,
            AE004891.1, AE004892.1, AE004893.1, AE004894.1, AE004895.1,
            AE004896.1, AE004897.1, AE004898.1, AE004899.1, AE004900.1,
            AE004901.1, AE004902.1, AE004903.1, AE004904.1, AE004905.1,
            AE004906.1, AE004907.1, AE004908.1, AE004909.1, AE004910.1,
            AE004911.1, AE004912.1, AE004913.1, AE004914.1, AE004915.1,
            AE004916.1, AE004917.1, AE004918.1, AE004919.1, AE004920.1,
            AE004921.1, AE004922.1, AE004923.1, AE004924.1, AE004925.1,
            AE004926.1, AE004927.1, AE004928.1, AE004929.1, AE004930.1,
            AE004931.1, AE004932.1, AE004933.1, AE004934.1, AE004935.1,
            AE004936.1, AE004937.1, AE004938.1, AE004939.1, AE004940.1,
            AE004941.1, AE004942.1, AE004943.1, AE004944.1, AE004945.1,
            AE004946.1, AE004947.1, AE004948.1, AE004949.1, AE004950.1,
            AE004951.1, AE004952.1, AE004953.1, AE004954.1, AE004955.1,
            AE004956.1, AE004957.1, AE004958.1, AE004959.1, AE004960.1,
            AE004961.1, AE004962.1, AE004963.1, AE004964.1, AE004965.1,
            AE004966.1, AE004967.1, AE004968.1, AE004091.1.
            -----------------------------------------------------------------
            This represents the Sept 08, 2010 version of the continually
            updated, reviewed, Pseudomonas aeruginosa PAO1 genome annotation
            from PseudoCap (see http://www.pseudomonas.com for the latest
            updates and links to alternate annotations). This update includes
            updated base pair coordinates and new features. PseudoCap is
            coordinated by Fiona S.L. Brinkman (Simon Fraser University,
            Canada) and Robert E.W. Hancock (University of British Columbia,
            Canada) with database development by Geoff Winsor (Simon Fraser
            University). We welcome submission through
            www.pseudomonas.com of any proposed changes.
            'Protein name confidence' is used to rate our confidence of the
            accuracy of the protein name.
            Class 1: Function experimentally demonstrated in P. aeruginosa.
            Class 2: Function of highly similar gene experimentally
            demonstrated in another organism (and gene context consistent in
            terms of pathways its involved in, if known).
            Class 3: Function proposed based on presence of conserved amino
            acid motif, structural feature or limited sequence similarity to an
            experimentally studied gene.
            Class 4: Homologs of previously reported genes of unknown function,
            or no similarity to any previously reported sequences.
            ------------------------------------------------------------------.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 18:04:58
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 2532658
            Orig. end    :: 2545669
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     subregion       1..13011
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="NRP"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..13011
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(11..6385)
                     /gene="ambE"
                     /locus_tag="PA2302"
     CDS             complement(11..6385)
                     /NRPS_PKS="Domain: AMP-binding (454-848). E-value: 2.4e-87.
                     Score: 285.0. Matches aSDomain:
                     nrpspksdomains_PA2302_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1256-1322). E-value: 1.2e-19.
                     Score: 62.1. Matches aSDomain: nrpspksdomains_PA2302_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (1358-1656). E-value:
                     2.2e-57. Score: 186.2. Matches aSDomain:
                     nrpspksdomains_PA2302_Condensation_DCL.1"
                     /NRPS_PKS="Domain: PP-binding (1792-1854). E-value:
                     1.3e-07. Score: 23.9. Matches aSDomain:
                     nrpspksdomains_PA2302_PP-binding.1"
                     /NRPS_PKS="Domain: Thioesterase (1885-2108). E-value:
                     1.5e-37. Score: 122.0. Matches aSDomain:
                     nrpspksdomains_PA2302_Thioesterase.1"
                     /codon_start=1
                     /gene="ambE"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     304.5; E-value: 1.9e-92)"
                     /gene_kind="biosynthetic"
                     /locus_tag="PA2302"
                     /note="Product name confidence: Class 1: Function
                     experimentally demonstrated in P. aeruginosa"
                     /product="AmbE"
                     /protein_id="AAG05690.1"
                     /sec_met_domain="Condensation (E-value: 3.3e-50, bitscore:
                     159.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.5e-95, bitscore:
                     307.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4e-16, bitscore:
                     47.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSASEDLQSAVQPAASEALEGFPLSPLQTRAWRRHAERPENTVVG
                     VRLHAPADPVATLERLRRALDGEAQLRVAYRTMPGMSLPVQVLDGRAADLLVERLPGDG
                     DWAGRFARESARLAASPLGGEGQPVLALGLLLDAAGETLQGLLLAAPAFVVDAASLVAL
                     LRRGLGPAGQASADEGDEALLFQHFSEWANEALAGEDGESASGYWREQAAVAAESPLAL
                     ADDLGEGEWTARRLLPRALLERLAANGLPEAAALLAWTQVAGQFQGDEGLPLEMARLVS
                     GRLFNEFAELAGPFAGVAPLCLENVRAGSVGERLDALQAAILAQEEAAALRDPFAPDWP
                     LAELGFAWLAGELDGAGVAELDCRQPPLGGFLELQVLPHGEGRLASLRVRRDHDGTLAG
                     RLLDAWVECLESIAADRQLPLAGLPLIGAAERERYQAWQGERVEPAPVESLVAAFDLRA
                     ALQPQAPALLDAHGSLDFATLRARSEAVAEALLAAGVRPGQAVAVMTGRNREAIVALLG
                     VMRAAAVYTPVNPEFPAARVERMREAGGIVFALADAECAGRAREAFAGACLDLSTLPLA
                     GSGMSLPAPGGRDAAYMIFTSGTSGQPKGVVVEHASALNLSQALARTVYANVVGEGLRV
                     TVNAPFSFDSSIKQILQLLSGHCLVLVPQEVRSDPQRMLGFLEERRIDVLDCTPSLFRL
                     LLQAGLDDAHPALPGRILVGGERFDEASWEVAAGWRRCQVFNLYGPTEATVNASLARVA
                     EHARPTIGRALANVDLHVVDGLGRRKTRGASGELWIGGAGVARGYAGDAGEAAGRFVEE
                     GWPGSGRLYRSGDLVRWRADGCLEFLGRIDEQVKINGYRIELGEIRSALLEHPAVGEAA
                     VLTDEADAAEPGADRRIVAFVTAAEETADESWLEVDLPSGHRVAGLNLNETEYVYQEIF
                     VDEVYSRDGIVLPPDAVVLDVGANIGLFSLYIASRAPRARVVAFEPLAPIRRRLEANLG
                     RYAPQVEVFGIGLSDAEREETFTYYPGYSTFSGIAEYADASGERDVIRRYLSNQGEEGG
                     ANLLLDNIDEILDDRLRAEAHRCRLRRLDQVIGELGLERIDLLKIDVQRAEMDVLLGLD
                     DAALAKVRQIVLEVHDKRDGATAGRADALSDLLRRHGFEVSIRQDALLEGTDRYNCYAV
                     RPGYAESLAERIDWRALAPRPAAALGGELSEQALRGFLEARLPAYMLPSRIARVERLPL
                     TAEGKLDRRALLAALAAEAAAQTLEAPANATEAALLEIWKSVLKRPAIGVSDNFFQVGG
                     DSIRLIQMQVMAREAGLAFTLRDVFNHQSIRELARLLAAPASPADALGTSAPQSLEPFA
                     LLSAAERKRLPEGLDDAYPMTSLQQGMLLQSEASGDPRLLHNVVLHEVHGRLDGELLAR
                     AWAILIGRHAILRTGFDLHGGQVPLQWVHPATAVAAEVPVHDLCGLDGETRRLRLRAWI
                     EEEQATPFDWSRPPLVRLAALALDERRFALGVAEHHSVLDGWSLQSLVDELLAVYADLL
                     AGVVAREAEAPAVGFRDYVALEREAEANAASALFWLDYLAGARYRPLPGLAEEGPRRMA
                     AVRVDVPADSLSRLRALAERSGLPLRSLLLAAHGRALCRFSDADEVVTGFVSHGRPEEP
                     GADRLLGLFLNTLPCRLSASVDLLDSARRAFDYERASLEHRRHPLAAIRRRNRELRLDS
                     LFNFVDFHQDDAAPAGVRHGGILDQVVVDVDVPLAVDFEVAGERLEVGFQYAAGRFPAE
                     RAEALAGAYREALLALLGDPVQPPAAAQAEDSVELRRVLKVLSRVLGRPLAADQGFASA
                     GGHSLLGVQAIAELRRLTGRQLSLGLLQGDPDAREVVRRCHAADAPPLPPATERARALW
                     LQRSGSAQPRLRLIALPPAGGNAGTFRGWDARLPADVELLAIQYPGRQERQDEPFVTDV
                     EAMLCAIDDALLPLLDRPFALIGASLGGMLAYELAARLESLHGLRARQLFVISSRAPGP
                     DLEYPRFHAMGDAELLRTLREYDVLPLEVLDDPELREISLATLRADSRLAADYRYRPRE
                     PLAIPITAILGEQDPGVSRVAIDGWRRHASRYELETLAGGHGLVVTAAEEVCAILRQRL
                     APDVPGGVPANLAT"
     aSDomain        complement(62..730)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PA2302_Thioesterase.1"
                     /evalue="1.50E-37"
                     /label="PA2302_Thioesterase.1"
                     /locus_tag="PA2302"
                     /protein_end="2108"
                     /protein_start="1885"
                     /score="122.0"
                     /tool="antismash"
                     /translation="RLIALPPAGGNAGTFRGWDARLPADVELLAIQYPGRQERQDEPFV
                     TDVEAMLCAIDDALLPLLDRPFALIGASLGGMLAYELAARLESLHGLRARQLFVISSRA
                     PGPDLEYPRFHAMGDAELLRTLREYDVLPLEVLDDPELREISLATLRADSRLAADYRYR
                     PREPLAIPITAILGEQDPGVSRVAIDGWRRHASRYELETLAGGHGLVVTAAEEVCAILR
                     Q"
     aSModule        62..2311
                     /domains="nrpspksdomains_PA2302_Condensation_DCL.1"
                     /domains="nrpspksdomains_PA2302_PP-binding.1"
                     /domains="nrpspksdomains_PA2302_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="PA2302"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(473..538)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2302_0010"
                     /evalue="7.40E-07"
                     /label="NRPS-te1"
                     /locus_tag="PA2302"
                     /protein_end="1971"
                     /protein_start="1949"
                     /score="21.7"
                     /tool="antismash"
                     /translation="RPFALIGASLGGMLAYELAARL"
     aSDomain        complement(824..1009)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PA2302_PP-binding.1"
                     /evalue="1.30E-07"
                     /label="PA2302_PP-binding.1"
                     /locus_tag="PA2302"
                     /protein_end="1854"
                     /protein_start="1792"
                     /score="23.9"
                     /tool="antismash"
                     /translation="RVLKVLSRVLGRPLAADQGFASAGGHSLLGVQAIAELRRLTGRQL
                     SLGLLQGDPDAREVVRR"
     aSDomain        complement(1418..2311)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PA2302_Condensation_DCL.1"
                     /domain_subtype="Condensation_DCL"
                     /evalue="2.20E-57"
                     /label="PA2302_Condensation_DCL.1"
                     /locus_tag="PA2302"
                     /protein_end="1656"
                     /protein_start="1358"
                     /score="186.2"
                     /tool="antismash"
                     /translation="DAYPMTSLQQGMLLQSEASGDPRLLHNVVLHEVHGRLDGELLARA
                     WAILIGRHAILRTGFDLHGGQVPLQWVHPATAVAAEVPVHDLCGLDGETRRLRLRAWIE
                     EEQATPFDWSRPPLVRLAALALDERRFALGVAEHHSVLDGWSLQSLVDELLAVYADLLA
                     GVVAREAEAPAVGFRDYVALEREAEANAASALFWLDYLAGARYRPLPGLAEEGPRRMAA
                     VRVDVPADSLSRLRALAERSGLPLRSLLLAAHGRALCRFSDADEVVTGFVSHGRPEEPG
                     ADRLLGLFLNTLPCRLS"
     CDS_motif       complement(1424..1513)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2302_0009"
                     /evalue="3.50E-08"
                     /label="C5_DCL_263-294"
                     /locus_tag="PA2302"
                     /protein_end="1654"
                     /protein_start="1624"
                     /score="25.9"
                     /tool="antismash"
                     /translation="VVTGFVSHGRPEEPGADRLLGLFLNTLPCR"
     CDS_motif       complement(1838..1900)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2302_0008"
                     /evalue="1.50E-08"
                     /label="C3_DCL_135-156"
                     /locus_tag="PA2302"
                     /protein_end="1516"
                     /protein_start="1495"
                     /score="27.1"
                     /tool="antismash"
                     /translation="HHSVLDGWSLQSLVDELLAVY"
     CDS_motif       complement(2132..2218)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2302_0007"
                     /evalue="2.00E-10"
                     /label="C2_DCL_024-062"
                     /locus_tag="PA2302"
                     /protein_end="1418"
                     /protein_start="1389"
                     /score="32.9"
                     /tool="antismash"
                     /translation="EVHGRLDGELLARAWAILIGRHAILRTGF"
     aSDomain        complement(2420..2617)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PA2302_PCP.1"
                     /evalue="1.20E-19"
                     /label="PA2302_PCP.1"
                     /locus_tag="PA2302"
                     /protein_end="1322"
                     /protein_start="1256"
                     /score="62.1"
                     /tool="antismash"
                     /translation="EAALLEIWKSVLKRPAIGVSDNFFQVGGDSIRLIQMQVMAREAGL
                     AFTLRDVFNHQSIRELARLLA"
     aSModule        2420..5023
                     /complete
                     /domains="nrpspksdomains_PA2302_AMP-binding.1"
                     /domains="nrpspksdomains_PA2302_PCP.1"
                     /locus_tags="PA2302"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(3815..3877)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2302_0006"
                     /evalue="7.20E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="PA2302"
                     /protein_end="857"
                     /protein_start="836"
                     /score="34.1"
                     /tool="antismash"
                     /translation="FLGRIDEQVKINGYRIELGEI"
     aSDomain        complement(3842..5023)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PA2302_AMP-binding.1"
                     /evalue="2.40E-87"
                     /label="PA2302_AMP-binding.1"
                     /locus_tag="PA2302"
                     /protein_end="848"
                     /protein_start="454"
                     /score="285.0"
                     /tool="antismash"
                     /translation="DLRAALQPQAPALLDAHGSLDFATLRARSEAVAEALLAAGVRPGQ
                     AVAVMTGRNREAIVALLGVMRAAAVYTPVNPEFPAARVERMREAGGIVFALADAECAGR
                     AREAFAGACLDLSTLPLAGSGMSLPAPGGRDAAYMIFTSGTSGQPKGVVVEHASALNLS
                     QALARTVYANVVGEGLRVTVNAPFSFDSSIKQILQLLSGHCLVLVPQEVRSDPQRMLGF
                     LEERRIDVLDCTPSLFRLLLQAGLDDAHPALPGRILVGGERFDEASWEVAAGWRRCQVF
                     NLYGPTEATVNASLARVAEHARPTIGRALANVDLHVVDGLGRRKTRGASGELWIGGAGV
                     ARGYAGDAGEAAGRFVEEGWPGSGRLYRSGDLVRWRADGCLEFLGRIDEQVKIN"
     CDS_motif       complement(3959..4042)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2302_0005"
                     /evalue="4.00E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="PA2302"
                     /protein_end="809"
                     /protein_start="781"
                     /score="28.8"
                     /tool="antismash"
                     /translation="GASGELWIGGAGVARGYAGDAGEAAGRF"
     CDS_motif       complement(4556..4615)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2302_0004"
                     /evalue="4.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="PA2302"
                     /protein_end="610"
                     /protein_start="590"
                     /score="28.5"
                     /tool="antismash"
                     /translation="AYMIFTSGTSGQPKGVVVEH"
     CDS_motif       complement(5483..5548)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2302_0003"
                     /evalue="4.60E+00"
                     /label="C5_LCL_267-296"
                     /locus_tag="PA2302"
                     /protein_end="301"
                     /protein_start="279"
                     /score="-0.1"
                     /tool="antismash"
                     /translation="VSGRLFNEFAELAGPFAGVAPL"
     CDS_motif       complement(5888..5926)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2302_0002"
                     /evalue="6.10E+01"
                     /label="C3_starter_134-155"
                     /locus_tag="PA2302"
                     /protein_end="166"
                     /protein_start="153"
                     /score="-2.9"
                     /tool="antismash"
                     /translation="VVDAASLVALLRR"
     CDS_motif       complement(6086..6127)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2302_0001"
                     /evalue="1.00E+01"
                     /label="C3_starter_134-155"
                     /locus_tag="PA2302"
                     /protein_end="100"
                     /protein_start="86"
                     /score="-0.5"
                     /tool="antismash"
                     /translation="VLDGRAADLLVERL"
     gene            complement(6405..7424)
                     /gene="ambD"
                     /locus_tag="PA2303"
     CDS             complement(6405..7424)
                     /codon_start=1
                     /gene="ambD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046:Dioxygenase TauD/TfdA (Score: 408.1; E-value:
                     3.2e-124)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="PA2303"
                     /note="Product name confidence: Class 1: Function
                     experimentally demonstrated in P. aeruginosa"
                     /product="AmbD"
                     /protein_id="AAG05691.1"
                     /transl_table=11
                     /translation="MSASFSAPRLRPRQLSAGDLVEESLLDPANDYLRIVRARQPGMDL
                     RQWIAAAGAGLRDSLLRHGGILFRGFAVDGAEGFSQAVQSFSPNMLDYLERAAARQEVA
                     HRVFTSTEFSPDGWIPPHHEMSYSHNWPSYIHFYCQTPPATQGRTPLADERRVSARIPE
                     AIRQRFLRHGVCYVRNYGPEIDLTWQEGFQTDSRAEVEAYCRQTGTQWTWLDDQRLNTR
                     QVRQAMVRHPLSGETLWFNHAHMFHVSNMPPALARALLDEVGEQGLPRNAYYGDGSPIE
                     AEVLDTIRAAYREETRAFAWERGDVLMLDNFISVHGREPYTGERKVLVAMTDLHVHQP"
     gene            complement(7421..8509)
                     /gene="ambC"
                     /locus_tag="PA2304"
     CDS             complement(7421..8509)
                     /codon_start=1
                     /gene="ambC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046:Dioxygenase TauD/TfdA (Score: 405.1; E-value:
                     2.6e-123)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="PA2304"
                     /note="Product name confidence: Class 1: Function
                     experimentally demonstrated in P. aeruginosa"
                     /product="AmbC"
                     /protein_id="AAG05692.1"
                     /transl_table=11
                     /translation="MERTAPSLTGRGFARPRNLSPRSSEALVRRPAAERDGLPLLIEAQ
                     APGLSLADWIREQGQSLHDDLNLAGGLLLRGFEVDSAERFRAAAAAFAPQLLDYKERSS
                     PRSQVSGEVYTSTEHPVDQPIFLHNEQSYTADWPLYIMFHCQVAPLEGGATPVAANRLV
                     LRHLPDELLERFGRLGILYVRNYRAGLGLSWREAFQTDSRAEVEAFCAEHRIAHAWIGD
                     EHLRTWQRRAAFQRHPYTGERLWFNHGMFFHATSLEPGLRDALLRSVAEEDLPYQTYYG
                     DGSPIEAQTLATIRSAIDRETRRFDWRVGDVLILDNMLAQHGREPFRGPRRILTIMSTP
                     YSSLAPADVPPTPPRLALGGAA"
     gene            complement(8539..12288)
                     /gene="ambB"
                     /locus_tag="PA2305"
     CDS             complement(8539..12288)
                     /NRPS_PKS="Domain: AMP-binding (244-633). E-value: 6.7e-98.
                     Score: 319.8. Matches aSDomain:
                     nrpspksdomains_PA2305_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (741-804). E-value: 1.4e-08.
                     Score: 27.0. Matches aSDomain:
                     nrpspksdomains_PA2305_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_LCL (822-1109). E-value:
                     7.6e-45. Score: 145.0. Matches aSDomain:
                     nrpspksdomains_PA2305_Condensation_LCL.1"
                     /codon_start=1
                     /gene="ambB"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     204.9; E-value: 4.3e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="PA2305"
                     /note="Product name confidence: Class 1: Function
                     experimentally demonstrated in P. aeruginosa"
                     /product="AmbB"
                     /protein_id="AAG05693.1"
                     /sec_met_domain="Condensation (E-value: 2.8e-36, bitscore:
                     113.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-100, bitscore:
                     325.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-09, bitscore:
                     27.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQERHGLPLRSFSSGKALTAGRAVRPEVAQERRYLQGAPLGLELP
                     GRIALRDPHCAWQWFEPEAAAEAFPAAHWLAAFLVLLGRYGNEEITLGFPEPITVRGRQ
                     APALLRSSYRAMESSAERSARLAEELDDARRQLSADGQERAALAGRCAVQVLAARPTAS
                     SPGWLALVLAADGSVGLALRDPQYDELRRIAGHLARLARGLVDAQACVGRLPWLDADEE
                     RRLQALRSEPQAAPSRGVLHHLFEAQARRTPQRIAVHAADRSLSYAELERESAALAVRL
                     RAAGVAPEQRVGVCLRRDSGLLVGLLGVLRAGGCYVPLDPAYPEERVAYMLDDADCLLV
                     LVDASTRERVAALGRPCLTLEEGGDQANDLALPASEVGADHLAYIIYTSGSTGRPKGVA
                     IEHGSAHAFLRWAGQHYAAEEWSGVLAATSVCFDLSVYELFGTLAEGGTLHLVENLFSL
                     PDYPRRDEISLLNTVPSVCAALLALGDLPGGVRTLNLAGEPLRGHLVRQIRGQPQVRRL
                     VNLYGPTEDTTYSTVHELDLHAEALDEPPIGRPLPGTTVEVLDGFEAPLPLGVAGELYL
                     GGIGLARGYFGKPEQTAERFRVDPGSGERRYRTGDRVRMREDGVLEHLGRLDDQVKFNG
                     FRIELGEIASCLASFPGVSEACAMLTEDSAGLRRLVGYLAAPFAPPLQALNEHLGQSLP
                     HYMLPSAFVVLAELPKTLNGKIDRKALPRPQATGAEPQALPSDPLEQALHQAWQAQLGA
                     PPRAGQGFYAAGGDSLRAVHLLATLRQRLSRRVPLQAFAGGPATPEALLELLRQAAPEG
                     DEPEPSAGAAGLSLAERRLWVAQQLAPEDTSYNLLAHLRIVGATADAIEQALRQLLERH
                     VALRRRVETGVDGPQPHALAAHAVPLQRLLASDAVHAERLLEDGVRREGARVFDLAHEA
                     PARLLLVVTRDSARADLLLSVHHYAFDDVSLAVFAAELKTLLDGGRLGVLASTPEQVAA
                     RERAALASGRLDRVAERWAERLLPLAKAPGAAPARPEESGGRAGQRLALPVSAAVHAAC
                     RALAERTSVSPFSAALQAFAEVLGAELGVDDLLVGVALAGRSRLEMQGLVGCFVNLLPL
                     AVGLRPEQSVEWRLRQVGHDLLELLEHQDVPLECVTQALRQRGASGLPIRIACGAHNGR
                     AAPAVDAGVRVEADFIPVPGARLDLTLWLEDQPQGWLAVWTGVSAIFDLHRIERLHQAW
                     ERRLLANAGEPISKRMSPEGCNAS"
     aSDomain        complement(8962..9822)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PA2305_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="7.60E-45"
                     /label="PA2305_Condensation_LCL.1"
                     /locus_tag="PA2305"
                     /protein_end="1109"
                     /protein_start="822"
                     /score="145.0"
                     /tool="antismash"
                     /translation="GLSLAERRLWVAQQLAPEDTSYNLLAHLRIVGATADAIEQALRQL
                     LERHVALRRRVETGVDGPQPHALAAHAVPLQRLLASDAVHAERLLEDGVRREGARVFDL
                     AHEAPARLLLVVTRDSARADLLLSVHHYAFDDVSLAVFAAELKTLLDGGRLGVLASTPE
                     QVAARERAALASGRLDRVAERWAERLLPLAKAPGAAPARPEESGGRAGQRLALPVSAAV
                     HAACRALAERTSVSPFSAALQAFAEVLGAELGVDDLLVGVALAGRSRLEMQGLVGCFVN
                     LLPLAV"
     CDS_motif       complement(8968..9054)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2305_0008"
                     /evalue="1.10E-10"
                     /label="C5_LCL_267-296"
                     /locus_tag="PA2305"
                     /protein_end="1107"
                     /protein_start="1078"
                     /score="33.9"
                     /tool="antismash"
                     /translation="DLLVGVALAGRSRLEMQGLVGCFVNLLPL"
     CDS_motif       complement(9376..9438)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2305_0007"
                     /evalue="1.10E-03"
                     /label="C3_LCL_132-143"
                     /locus_tag="PA2305"
                     /protein_end="971"
                     /protein_start="950"
                     /score="11.7"
                     /tool="antismash"
                     /translation="VHHYAFDDVSLAVFAAELKTL"
     CDS_motif       complement(9664..9759)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2305_0006"
                     /evalue="4.00E-02"
                     /label="C2_dual_024-063"
                     /locus_tag="PA2305"
                     /protein_end="875"
                     /protein_start="843"
                     /score="6.6"
                     /tool="antismash"
                     /translation="YNLLAHLRIVGATADAIEQALRQLLERHVALR"
     aSDomain        complement(9877..10065)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PA2305_PP-binding.1"
                     /evalue="1.40E-08"
                     /label="PA2305_PP-binding.1"
                     /locus_tag="PA2305"
                     /protein_end="804"
                     /protein_start="741"
                     /score="27.0"
                     /tool="antismash"
                     /translation="ALHQAWQAQLGAPPRAGQGFYAAGGDSLRAVHLLATLRQRLSRRV
                     PLQAFAGGPATPEALLEL"
     aSModule        9877..11556
                     /complete
                     /domains="nrpspksdomains_PA2305_AMP-binding.1"
                     /domains="nrpspksdomains_PA2305_PP-binding.1"
                     /locus_tags="PA2305"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(10285..10323)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2305_0005"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="PA2305"
                     /protein_end="668"
                     /protein_start="655"
                     /score="-3.2"
                     /tool="antismash"
                     /translation="ACAMLTEDSAGLR"
     CDS_motif       complement(10360..10422)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2305_0004"
                     /evalue="4.00E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="PA2305"
                     /protein_end="643"
                     /protein_start="622"
                     /score="31.8"
                     /tool="antismash"
                     /translation="HLGRLDDQVKFNGFRIELGEI"
     aSDomain        complement(10390..11556)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PA2305_AMP-binding.1"
                     /evalue="6.70E-98"
                     /label="PA2305_AMP-binding.1"
                     /locus_tag="PA2305"
                     /protein_end="633"
                     /protein_start="244"
                     /score="319.8"
                     /tool="antismash"
                     /translation="FEAQARRTPQRIAVHAADRSLSYAELERESAALAVRLRAAGVAPE
                     QRVGVCLRRDSGLLVGLLGVLRAGGCYVPLDPAYPEERVAYMLDDADCLLVLVDASTRE
                     RVAALGRPCLTLEEGGDQANDLALPASEVGADHLAYIIYTSGSTGRPKGVAIEHGSAHA
                     FLRWAGQHYAAEEWSGVLAATSVCFDLSVYELFGTLAEGGTLHLVENLFSLPDYPRRDE
                     ISLLNTVPSVCAALLALGDLPGGVRTLNLAGEPLRGHLVRQIRGQPQVRRLVNLYGPTE
                     DTTYSTVHELDLHAEALDEPPIGRPLPGTTVEVLDGFEAPLPLGVAGELYLGGIGLARG
                     YFGKPEQTAERFRVDPGSGERRYRTGDRVRMREDGVLEHLGRLDDQVKF"
     CDS_motif       complement(10501..10590)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2305_0003"
                     /evalue="8.00E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="PA2305"
                     /protein_end="596"
                     /protein_start="566"
                     /score="50.1"
                     /tool="antismash"
                     /translation="PLGVAGELYLGGIGLARGYFGKPEQTAERF"
     CDS_motif       complement(11083..11142)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2305_0002"
                     /evalue="7.20E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="PA2305"
                     /protein_end="402"
                     /protein_start="382"
                     /score="33.8"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGRPKGVAIEH"
     CDS_motif       complement(11329..11370)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PA2305_0001"
                     /evalue="4.30E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="PA2305"
                     /protein_end="320"
                     /protein_start="306"
                     /score="16.7"
                     /tool="antismash"
                     /translation="LGVLRAGGCYVPLD"
     gene            complement(12384..13001)
                     /gene="ambA"
                     /locus_tag="PA2306"
     CDS             complement(12384..13001)
                     /codon_start=1
                     /gene="ambA"
                     /gene_functions="transport (smcogs)
                     SMCOG1116:Homoserine/threonine efflux protein (Score:
                     180.3; E-value: 5.7e-55)"
                     /gene_kind="transport"
                     /locus_tag="PA2306"
                     /note="Product name confidence: Class 1: Function
                     experimentally demonstrated in P. aeruginosa"
                     /product="AmbA"
                     /protein_id="AAG05694.1"
                     /transl_table=11
                     /translation="MSLSVDLLLAFSLFAFVTSVTPGPNNTMLLASGVNFGFVRSIPHI
                     LGISCGFFIMVMAVGFGLGTVFEAYPVLYTILRYVGAAYLLYLAWKIATSGPAGNDPEG
                     RGKPLSYWGAAAFQWVNPKAWVMAVGAISTYTPLQGYFTNVVVISTVFALINAPTIGIW
                     AGFGSMLRNVLRDPRWLRVFNVGMALLLVASLYPILAESHSA"
ORIGIN
        1 ggccggcggt tcaggttgcc aggttcgccg gcacgccgcc aggcacatcg ggcgccaggc
       61 gctgccgcag gatcgcgcag acctcctccg ccgccgtcac caccaggccg tggccgccgg
      121 ccagggtctc cagctcgtag cggctggcgt gccgccgcca gccgtcgatg gccaccctgg
      181 agacgcccgg gtcctgctcg ccgaggatcg cggtgatcgg tatggccagc ggctcgcgcg
      241 ggcggtagcg atagtcggcg gccaggcgcg aatcggcgcg cagggtggcc aggctgatct
      301 cgcgcagctc cgggtcgtcg agcacttcca gcggcagcac gtcgtactcg cgcagggttc
      361 gcagcaactc ggcgtcgccc atcgcatgga agcgcgggta ttccaggtcc ggccccggag
      421 cgcggctgct gatcacgaac aactgcctgg cgcgcaggcc gtgcaggctt tccaggcgtg
      481 ccgccagttc gtaggcgagc atgccgccga ggctggcgcc gatcagggcg aacggacggt
      541 cgagcaatgg caggagcgcg tcgtcgatgg cacagagcat ggcctctaca tcggtgacga
      601 atggctcgtc ctggcgttcc tggcgccccg gatactggat cgccagcagc tccacgtccg
      661 ccggcaggcg cgcgtcccaa ccacggaaag tgccggcgtt gccgcccgcg ggcggcagcg
      721 cgatcaggcg caggcgcggc tgcgcgctcc cgctgcgctg caaccacagg gcccgggcgc
      781 gctcggtggc gggcggcaac ggcggcgcgt cggcggcatg gcagcggcgc accacttcgc
      841 gggcatccgg atcgccctgc aacagcccca ggctcagttg cctgccggtc agccggcgca
      901 attcggcgat cgcctgcacg cccagcagcg aatgcccgcc ggcgctggcg aagccctggt
      961 cggccgccag cggccggccg agcacccggg acaacacctt gagcacccgc cgcagctcca
     1021 cgctgtcctc ggcctgggcc gccgcgggcg gctgcaccgg gtctccgagc agcgccagca
     1081 acgcctcgcg gtaggcgccg gccagtgcct cggcgcgctc ggcggggaaa cgtccggcgg
     1141 catactggaa gcccacctcg aggcgctcgc cggccacctc gaagtccacc gccagcggca
     1201 cgtcgacgtc caccaccacc tggtcgagga tgccgccgtg ccttactccc gccggcgcgg
     1261 cgtcgtcctg gtggaagtcg acgaagttga acaggctgtc caggcgcaac tcgcggttgc
     1321 gcctgcgaat cgccgccagc ggatggcgcc gatgttccag gctcgcgcgc tcgtagtcga
     1381 atgcgcgacg ggcgctgtcg agcagatcga cggaagccga cagccggcac ggcagggtgt
     1441 tcaggaacag gccgagcagg cggtccgctc ccggctcctc ggggcgcccg tggctgacga
     1501 agccggtgac tacttcatcg gcatcgctga agcggcacaa cgctcggcca tgcgccgcca
     1561 gcaacaacga acgcaagggc aagccgctgc gttcggccag ggcgcgcaag cgcgacaggc
     1621 tgtcggccgg cacgtccacg cggaccgccg ccatgcgccg gggtccctcc tccgccaggc
     1681 cgggcaacgg ccggtagcgg gcgccggcca ggtagtcgag ccagaacagc gccgaggcgg
     1741 cgttggcctc ggcctcacgc tccagcgcca cgtagtcgcg gaagcctacc gcgggcgctt
     1801 ccgcttcccg cgcgacgaca ccggcgagaa ggtcggcgta gaccgccagc agctcgtcca
     1861 ccaggctttg caggctccag ccgtccagca cgctatggtg ttcggcgacg cccagggcga
     1921 agcgccgctc gtccagcgcc agcgcggcga ggcgcaccag cggtgggcgg ctccagtcga
     1981 acggggtggc ctgctcttcc tcgatccagg cacgcaggcg caggcgccgt gtttccccat
     2041 cgaggccaca caggtcgtgc accggcacct cggcggcgac cgccgtggcc gggtggaccc
     2101 attgcagggg aacctggcca ccgtgcagat cgaagccggt acgcaggatc gcgtggcggc
     2161 cgatcaggat cgcccaggcg cgcgccagca actcgccgtc caggcgtcca tgcacctcgt
     2221 gcaggacgac gttgtgcaac agccgtggat cgccgctggc ctcgctttgc aggagcatgc
     2281 cctgttgcag gctggtcatc ggataggcgt cgtcgagccc ctccggcagg cgcttgcgtt
     2341 ccgccgccga caacagggcg aacggctcca gcgactgcgg cgccgaggtc ccgagcgcat
     2401 ccgccggact cgccggagcg gccagcaggc gcgccagttc gcggatgctc tggtggttga
     2461 acacgtcgcg cagggtaaag gcaagccccg cctcgcgcgc catgacctgc atctggatca
     2521 ggcggatgga gtcgccgccg acctggaaga aattgtcgct gacgccgatc gccgggcgtt
     2581 tcagcacgct cttccagatc tccagcaggg ccgcctcggt ggcattggcc ggcgcttcca
     2641 gggtctgcgc ggccgcctcg gcggccagcg ccgccaacag cgcgcgacgg tcgagcttgc
     2701 cttcggcggt cagcggcagg cgttcgaccc gggcgatccg gctcggcagc atgtaggccg
     2761 gcaggcgcgc ctcgaggaag ccacgcaggg cctgctcgct cagctcgccg ccgagggccg
     2821 cggcggggcg cggcgcgagc gcgcgccagt cgatgcgctc agccagcgac tcggcatagc
     2881 ccgggcgcac cgcgtagcag ttgtaacggt cggtaccctc cagcagcgcg tcctgacgga
     2941 tgctcacctc gaagccatgg cggcgcagca ggtcgctcaa ggcatcggcg cggccggcgg
     3001 tggcaccgtc gcgcttgtca tggacctcca ggacgatctg ccggaccttg gccagcgccg
     3061 catcgtcgag accgagcagc acatccattt ccgcgcgctg cacgtcgatc ttcagcaggt
     3121 cgatacgctc caggcccagt tcgccgatca cctggtcgag gcggcgcagg cggcagcggt
     3181 gggcttcggc gcgcaggcgg tcgtcgagga tttcgtcgat gttgtccagc agcaggttgg
     3241 ccccgccctc ctcgccctgg ttgctcaggt agcgtcggat gacgtcgcgt tcgccgctgg
     3301 cgtcggcgta ctcggcgatc ccggagaagg tcgagtagcc cggatagtag gtgaaggttt
     3361 cctcacgctc ggcgtcggac agaccgatgc cgaatacctc gacctgcggt gcgtagcgtc
     3421 cgaggttggc ctccaggcgc cggcggatcg gtgccagcgg ctcgaaggcg accactcgcg
     3481 cgcgcggcgc gcggctggcg atgtacagcg agaacaggcc gatgttggca ccgacgtcga
     3541 ggaccaccgc gtccggcggc aggacgatgc cgtcgcggct gtagacctcg tcgacgaaga
     3601 tttcctggta gacgtactcg gtttcgttga ggttcagtcc ggcgacccgg tgcccgctgg
     3661 gcaggtcgac ttccagccag gactcgtccg cggtctcctc ggcggcggtg acgaaggcga
     3721 cgatccggcg atccgcgccc ggttcggccg catcggcctc gtcggtgagt accgccgcct
     3781 cgcccaccgc cgggtgttcc agcaacgcgc tgcggatctc gcccagttcg atgcggtagc
     3841 cgttgatctt cacctgttcg tcgatccgcc cgaggaactc caggcaaccg tcggcgcgcc
     3901 agcgcaccag gtcgccgctg cggtacaggc ggccgctgcc cggccagccc tcctcgacga
     3961 agcgcccggc cgcctcgccg gcgtcgccgg catagccgcg cgccaccccg gcgccgccga
     4021 tccacagttc gccgctggcg ccacgggtct tgcgacgacc gaggccatcg accacatgca
     4081 gatcgacgtt ggccagggcg cggccgatgg tcggccgcgc atgctcggcg acccgcgcca
     4141 ggctggcgtt caccgtggct tcggtaggac cgtagagatt gaacacctgg cagcggcgcc
     4201 agccggcggc gacctcccag gacgcttcgt cgaagcgctc gccccctacc aggatgcgcc
     4261 cgggcagcgc cgggtgggca tcgtcgaggc cggcctggag cagcaggcgg aacagcgacg
     4321 gggtgcagtc gagcacgtcg atgcgccgtt cttcgaggaa ccccagcatc cgctgcggat
     4381 cgctgcgcac ctcctgcggc accaggacca ggcaatggcc ggagagcaac tggagaatct
     4441 gcttgatcga ggagtcgaag gagaacggcg cgttgaccgt cacccgcagg ccctcgccca
     4501 ccacgttcgc gtataccgtg cgcgccaggg cctgggacag gttgagcgcg ctggcgtgct
     4561 cgaccaccac gcctttgggc tggccgctgg tgcccgaggt gaagatcatg taggccgcat
     4621 cgcgcccgcc cggcgccggc aggctcatgc cgctgccggc aagcggcagc gtcgacaggt
     4681 ccaggcaggc cccggcgaag gcctcgcggg cgcgcccggc gcactcggca tcggcaaggg
     4741 cgaagacgat cccgcccgct tcgcgcatcc gctccacccg cgccgccgga aactccggat
     4801 tgaccggggt gtacaccgcc gccgcgcgca tcaccccgag cagggcgacg atcgcctcgc
     4861 ggttgcgccc ggtcatcacc gccaccgcct ggccgggccg cacgccggca gccagcagcg
     4921 cttcggcgac cgcttcgctg cgcgcgcgca gcgtggcgaa atccaggctg ccgtgggcat
     4981 ccagcaacgc cggcgcctgc ggctgcaggg cggcgcgcag atcgaacgcg gccaccaggg
     5041 attccaccgg cgcgggctcc acgcgctcgc cctgccaggc ctggtagcgc tcgcgctcgg
     5101 ccgcgccgat caacggcagc ccggccagtg gcagttgcct gtcggcggcg atgctttcca
     5161 ggcattcgac ccaggcgtcg agcaagcgcc cggccagcgt tccgtcatgg tcgcgacgga
     5221 cccgcaggct ggccagcctg ccttcgccgt ggggcagcac ctgcaactcg aggaacccgc
     5281 ccagcggcgg ctgacggcaa tccagctcgg ccaccccggc gccatccagt tcgcccgcca
     5341 gccaggcgaa gcccaactcg gcgagcggcc agtcgggggc aaagggatcg cgcagggccg
     5401 ctgcctcctc ctgggcgagg atcgccgcct ggagggcgtc gagccgctcg ccgacgctgc
     5461 ccgcgcggac attctccagg cacagcggcg cgaccccggc gaacggtccg gccagctcgg
     5521 cgaactcgtt gaacaggcgc cccgagacca gtcgcgccat ttccagcggg aggccctcgt
     5581 cgccctggaa ctgcccggcg acctgggtcc aggccagcag ggcggccgcc tccggcaagc
     5641 cgttggcggc caggcgttcg agcagcgcgc gcggcagcag gcgccgcgcc gtccactcgc
     5701 cttcgcccag gtcgtccgcc agcgccagcg gactctccgc cgcaacggcc gcctgctctc
     5761 gccagtaacc gctggcgctt tcgccgtctt cgccggccag cgcctcgttg gcccactcgg
     5821 agaaatgctg gaacagcagc gcctcgtctc cctcgtccgc gctcgcctgg ccggccggcc
     5881 ccaggccgcg gcgcagcagc gccaccaggc tggccgcatc gacgacgaac gccggcgccg
     5941 ccagcaacag cccctggagc gtctctccgg cggcgtccag cagcaggccg agcgccagta
     6001 ccggctggcc ttccccgccc aggggcgaag cggcgagacg cgcgctttcg cgcgcgaagc
     6061 gtccggccca gtcgccgtct cccggcaggc gctcgaccag cagatcggcc gcgcgcccat
     6121 ccagtacctg caccggcagg ctcatgcccg gcatcgtccg gtaggccacg cgcagttgcg
     6181 cctcgccgtc cagcgcccgg cgcagccgct ccagcgtcgc cacgggatcg gccggggcgt
     6241 gcaggcgcac gccgacaacc gtattttccg gccgctcggc atggcggcgc caggcgcggg
     6301 tctgcaaggg agacagcggg aatccttcga gcgcttcgct cgcggccggt tgcacagcgg
     6361 attgcaggtc ttctgacgca ctcatggcta tccctcgcac gggttcaggg ttggtggaca
     6421 tgcaggtcgg tcatcgccac cagcaccttg cgctcgccgg tgtacggctc gcggccgtgg
     6481 acgctgatga agttgtcgag catcaggaca tcgccgcgct cccaggcgaa cgcgcgggtt
     6541 tcctcgcggt aggcggcgcg gatggtgtcc agcacctccg cctcgatcgg gctgccgtcg
     6601 ccgtagtagg cgttgcgcgg caggccctgt tcgccgacct cgtcgagcaa ggcccgggcc
     6661 agggccggcg gcatgttgga gacatggaac atgtgcgcgt ggttgaacca cagcgtctcg
     6721 ccgctgagcg ggtggcgcac catcgcctgg cgtacctggc gggtattcag gcgctggtcg
     6781 tcgagccagg tccattgggt accggtctgc cggcagtagg cctcgacctc ggcgcgactg
     6841 tcggtctgga agccttcctg ccaggtcagg tcgatctccg gcccgtagtt gcgcacgtag
     6901 cacaccccat ggcggaggaa gcgctgcctg atcgcctcgg gtatccgagc gctgacccgg
     6961 cgctcgtcgg ccaggggcgt gcggccctgg gtggcgggcg gtgtctggca gtagaagtgg
     7021 atatagctcg gccagttgtg cgagtaggac atctcgtggt gcggcggaat ccagccgtcc
     7081 ggcgagaact cggtggaggt gaacacccgg tgcgccactt cctggcgtgc cgccgcgcgc
     7141 tccaggtagt cgagcatgtt cggcgaaaag ctttgtaccg cctgggagaa gccctccgct
     7201 ccgtctaccg cgaagccacg aaacaggatg ccgccatgcc gcagcaggct gtcgcgcagc
     7261 cctgcgccgg cggcggcgat ccattgccgc aggtccatgc ccggctggcg cgcgcggacg
     7321 atgcgcagat agtcgttggc cgggtcgagc aggctttcct ccaccaggtc gccggccgag
     7381 agctgccggg ggcgcaggcg cggcgcgctg aacgaggcgc tcatgcggca cctccgagcg
     7441 ccaggcgcgg aggtgtcggc gggacgtcgg cgggcgccag gctggaatac ggcgtggaca
     7501 tgatggtgag gatccgtcgc ggcccgcgga acggctcgcg gccgtgctgg gcgagcatgt
     7561 tgtcgaggat cagcacgtcg cccacgcgcc agtcgaagcg ccgcgtctcg cggtctatgg
     7621 cgctgcggat ggtcgccagg gtctgcgcct cgatcgggct gccatcgccg tagtaggtct
     7681 ggtacggcag gtcttcctcg gcgacgctgc gcagcagcgc atcgcgcagg cccggctcga
     7741 gactggtggc atggaagaac atgccgtggt tgaaccacag gcgctcgccg gtatacgggt
     7801 ggcgttggaa cgccgcgcgc ctctgccagg tgcgcaggtg ctcgtcgccg atccaggcat
     7861 gggcgatccg gtgctcagcg cagaacgcct cgacctcggc gcggctgtcg gtctggaacg
     7921 cttcgcgcca ggacaggccg aggccggcgc ggtagttgcg cacgtagagg atgcccaggc
     7981 gcccgaagcg ttccagcaat tcgtccggca ggtggcggag caccagccgg ttggccgcca
     8041 ccggagtggc gccgccctcg agcggcgcga cctggcaatg gaacatgatg tacagcggcc
     8101 agtcggcggt ataggactgc tcgttatgca ggaagatcgg ctggtccacc ggatgctcgg
     8161 tggaggtgta gacctcgccg ctgacctggc tacgcggcga ggaacgctcc ttgtagtcga
     8221 gcagttgcgg ggcgaaggca gcggcggctg cgcggaagcg ctccgccgag tcgacctcga
     8281 agcctctcag caacaggccg ccagccaggt tcaggtcgtc gtgcagggac tggccctgct
     8341 cgcgaatcca gtcggccagg gacaggccgg gagcctgtgc ctcgatcagc agcggcaggc
     8401 cgtcgcgctc cgccgccggg cgccgcacca gcgcctcgct gctgcgcggg ctgagattgc
     8461 gcggccgggc gaagccgcga ccggtgagac tgggagctgt tcgttccatc gctgttctcc
     8521 gtgggaggct cggggtcgtc aggaagcgtt gcagccctcc ggcgacatgc gtttcgagat
     8581 aggttcgccg gcattcgcca gcaggcgccg ctcccaggcc tggtgcaggc gctcgatgcg
     8641 gtgcaggtcg aagatcgcgc tgaccccggt ccagacggcc agccaaccct gcggctggtc
     8701 ttccagccac agcgtcaggt ccaggcgcgc gccaggcacc gggatgaagt cggcttcgac
     8761 gcgcaccccg gcatccaccg ccggggccgc ccgaccgttg tgcgcgccgc aggcgatgcg
     8821 gatcggcagg ccgctggcgc cgcgctggcg cagggcctgg gtcacgcatt cgaggggcac
     8881 gtcctggtgt tcgagcagtt ccagcagatc atggccgacc tggcgcaggc gccactccac
     8941 ggactgctcc ggacgcaggc cgaccgccag cggcaggagg ttgacgaagc agccgaccag
     9001 cccctgcatt tccaggcgcg aacgcccggc cagggccacg ccgacgagca ggtcgtcgac
     9061 gcccagttcg gcgccgagca cttcggcgaa ggcctgtagc gcagcactga acgggcttac
     9121 cgaggtgcgt tcggccagcg cccggcaggc ggcatggacg gcggcggaaa ccggcagggc
     9181 gaggcgttgg ccggcgcgcc cgccgctctc ctccgggcgc gccggcgcgg cgccgggagc
     9241 cttcgccagc ggcaacaaac gctcagccca gcgctcggcg acacggtcca ggcgtcccga
     9301 ggccaacgcc gcgcgctcgc gggcggcaac ctgttccggc gtgctggcga gcacgcccag
     9361 gcgaccgcca tcgagcagcg tcttcagttc cgcggcaaag accgccagcg acacatcgtc
     9421 gaaggcgtag tgatggacgc tgagcaggag gtcggcgcgc gcgctgtcgc gggtgacgac
     9481 cagcagcagg cgtgccggcg cctcgtgggc gaggtcgaag actcgcgcgc cctcacggcg
     9541 cacgccatcc tccagcaacc gctcggcgtg gacggcgtcg ctcgccagca ggcgttgcag
     9601 gggcaccgca tgcgccgcca gcgcatgcgg ctgcggcccg tcgacgcccg tttcgacacg
     9661 ccggcgcagc gccacatgcc gttccagcaa ctggcgcaag gcctgttcga tggcgtcggc
     9721 cgtggcgccg actatgcgca ggtgggccag caggttgtag gaggtgtcct ccggcgccag
     9781 ttgctgggcc acccacaggc gccgttcggc gaggctcagc ccggcggcgc cggcgctcgg
     9841 ctccggctcg tcgccctcgg gcgcggcctg gcgcagcagt tccagcaggg cctcgggggt
     9901 cgccgggcca ccggcgaacg cctgcaacgg tacgcgtcgg gacagtcgct ggcgcagcgt
     9961 cgcgagcagg tgcaccgccc gcagggaatc gccgccggcg gcgtagaagc cctgtccggc
    10021 gcgcggcggc gcaccaagct gcgcctgcca ggcctggtgt agcgcctgct ccagcggatc
    10081 gctgggcagc gcctgcggct cggcgccggt cgcctgggga cgcggcaggg ccttgcggtc
    10141 gatcttgccg ttgagcgtct tgggcagctc cgccaggacc acgaacgccg acggcaacat
    10201 gtagtgcggc agactttgcc caaggtgctc gttcagcgcc tggagcggcg gggcgaacgg
    10261 cgccgccagg tagccgacca gccgacgcag gccggcgctg tcctcggtga gcatggcgca
    10321 ggcttcgctc accccgggaa aactcgccag gcacgaggcg atctcaccca gctcgatgcg
    10381 gaagccgttg aacttgacct ggtcgtcgag ccggccgagg tgttccagca cgccgtcctc
    10441 gcgcatgcgt acgcggtcgc cggtgcgata gcggcgctcg ccgctgcccg gatcgacgcg
    10501 gaaacgctcg gcggtctgct ccggcttgcc gaaatagcca cgcgccaggc cgatgccgcc
    10561 gaggtacagc tccccggcca cgcccagcgg cagcggcgcc tcgaagccgt cgagcacctc
    10621 caccgtggtg ccgggcagcg gtcggccgat gggcggctcg tcgagcgctt cggcgtgcag
    10681 gtccagttcg tgcaccgtcg aataggtggt gtcctcggtc ggcccgtaga gattgaccag
    10741 gcgccgtacc tggggttggc cacgaatctg tcgcaccagg tggccgcgca gcggttcgcc
    10801 ggccaggttc agcgtgcgca ccccgcccgg caggtcgccg agggcgagca gcgcggcgca
    10861 caccgagggc acggtattga gcaggctgat ctcgtcgcgg cgcgggtagt ccggcaggct
    10921 gaacaggttt tccaccaggt gcagcgtgcc gccttcggcc agggtgccga acagctcgta
    10981 gaccgacagg tcgaagcaca ccgaggtcgc cgccagtacc ccgctccatt cttcggcggc
    11041 atagtgctgg ccggcccagc gcaggaaggc atgggcgctg ccgtgctcga tggcgacgcc
    11101 cttggggcgt ccggtggatc cggaggtata gatgatgtag gcgaggtggt cggcgccgac
    11161 ctcgctcgcg ggcagcgcca ggtcgttcgc ctggtcgccg ccctcctcca gcgtcaggca
    11221 tggccggccc agcgcggcga cccgctcgcg ggtgctcgcg tcgaccagca ccagcaggca
    11281 gtcggcgtcg tcgagcatgt aggccacccg ctcctccgga taggccgggt ccagcgggac
    11341 gtagcaaccg ccggcgcgga gcacgccaag caggccgacc agcaggccgc tgtcgcgccg
    11401 caggcagacc ccgacccgct gctccggagc caccccggcg gcgcgcaggc gcacggcgag
    11461 cgcggcgctt tcgcgctcca gctcggcata gctgaggcta cggtcggcgg cgtgcacggc
    11521 gatgcgctgc ggtgtgcgcc gcgcctgggc ctcgaacaga tggtggagta cgccgcgcga
    11581 cggggcggcc tggggctcgc tgcgcagggc ctgcaaacgg cgctcttcgt cggcgtccag
    11641 ccagggcagc cggccgacgc aggcctgggc gtcgaccagg ccgcgcgcca ggcgcgcgag
    11701 atggccggcg atacgccgca attcgtcgta ctggggatcg cgcagagcca ggccgacgct
    11761 gccgtccgcc gccagcacca gggccagcca gccggggctg ctcgccgtcg gccgcgccgc
    11821 cagcacctgg accgcgcagc gcccggccag ggcggcgcgc tcctggccgt cggcggatag
    11881 ctgccgccgg gcgtcatcga gttcttccgc cagccgcgcg ctacgttcgg cggacgactc
    11941 catcgcccgg taggaggaac gcagcagcgc gggcgcctgc cgcccgcgaa ccgtgatcgg
    12001 ctcgggaaag cccagggtga tctcttcgtt gccgtagcgt cccagcagta ccaggaacgc
    12061 cgccagccag tgcgccgccg ggaacgcttc cgcggccgcc tccggctcga accattgcca
    12121 ggcgcaatgc gggtcgcgca aggcgattcg tcccggcaac tccagcccca gcggggcgcc
    12181 ttgcaggtag cgccgctcct gcgcaacctc cgggcgcact gcgcgtcccg cggtcagcgc
    12241 cttgcccgac gaaaagctgc gtaacggtaa gccatgtcgc tcctgcatcg ctctccccct
    12301 tccgaggctg ggcaccgagc gaaaaactct tcacgaaatg gcgacgagtt acgagctaat
    12361 acaattgata gggtggtgac aggtcaggcc gaatggcttt ccgcgaggat cgggtacagc
    12421 gacgcgacca acagcagcgc catccctacg ttgaacaccc tcagccagcg cggatcgcgc
    12481 agcacgttgc gcagcatgct gccgaaaccg gcccagattc cgatggtcgg cgcgttgatc
    12541 agggcaaata ccgtggagat caccaccacg ttggtgaagt agccctgcaa cggcgtatag
    12601 gtgcttatgg cgccgaccgc catcacccag gccttcgggt tgacccactg gaacgccgcc
    12661 gcgccccagt agctcaacgg cttgccacgt ccctccgggt cgttgccggc cgggccggac
    12721 gtggcgatct tccaggccag gtacagcagg tacgccgcgc cgacgtagcg caggatggtg
    12781 tacagcaccg gataggcctc gaacaccgtg cccaggccga agcccaccgc catcaccatg
    12841 atgaagaagc cgcaactgat cccgaggatg tgcgggatgg agcggacgaa accgaagttg
    12901 acccccgagg ccagcaacat ggtgttgttc ggaccgggcg tgacggaggt gacgaaggcg
    12961 aacagggaga acgccagcag cagatccacg gagagcgaca ttcgttccat c
//
