BGC0000292 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000292 (Aspergillus terreus NIH2624)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	27,623	acetylaranotin	NRPS:Type I	100%

BGC0000292 - Region 1 - NRPS

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Location: 1 - 27,623 nt. (total: 27,623 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 27,624
Label		BGC0000292

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000292	1.00	NRP	acetylaranotin	Aspergillus terreus NIH2624
BGC0002736	0.32	Terpene	preaspterpenacid I	Aspergillus terreus NIH2624
BGC0002321	0.31	Other	pulcherriminic acid, pulcherrimin, cyclodileucine, compound 3	Metschnikowia aff. pulcherrima
BGC0001989	0.31	Other	pulcherrimin	Kluyveromyces lactis
BGC0000677	0.31	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0000676	0.28	Terpene	aphidicolin, aphidicolan-16β-ol, 3-deoxyaphidicolin, 17-deoxyaphidicolin	Phoma betae
BGC0002157	0.26	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0002242	0.26	NRP	oxepinamide D	Aspergillus ustus
BGC0001873	0.26	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0002135	0.25	NRP	bovienimide A	Xenorhabdus bovienii SS-2004

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000292	1.00	NRP	acetylaranotin	Aspergillus terreus NIH2624
BGC0002736	0.66	Terpene	preaspterpenacid I	Aspergillus terreus NIH2624
BGC0002321	0.65	Other	pulcherriminic acid, pulcherrimin, cyclodileucine, compound 3	Metschnikowia aff. pulcherrima
BGC0001989	0.64	Other	pulcherrimin	Kluyveromyces lactis
BGC0000677	0.64	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0000676	0.62	Terpene	aphidicolin, aphidicolan-16β-ol, 3-deoxyaphidicolin, 17-deoxyaphidicolin	Phoma betae
BGC0002157	0.60	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0002242	0.60	NRP	oxepinamide D	Aspergillus ustus
BGC0001873	0.59	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0002135	0.59	NRP	bovienimide A	Xenorhabdus bovienii SS-2004

Similar known gene clusters from MIBiG 4.0

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 27623:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Phe)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ATEG_03470

Search NORINE for peptide: strict or relaxed

AMP-binding (513..893): Phe

nrpys: Phe

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DGHIYVMCGK
Nearest Stachelhaus code(s):: Phe DGHIYVMCGK (100% 8Å match)
Stachelhaus code match:: 100% (strong)