LOCUS       BGC0000295             13141 bp    DNA     linear   BCT 25-APR-2013
DEFINITION  Acinetobacter haemolyticus DNA, acinetoferrin biosynthesis gene
            cluster and transport genes, strain: ATCC 17906.
ACCESSION   BGC0000295
VERSION     BGC0000295
KEYWORDS    .
SOURCE      Acinetobacter haemolyticus
  ORGANISM  Acinetobacter haemolyticus
            Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales;
            Moraxellaceae; Acinetobacter.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 18:08:59
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13141
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..13141
                     /db_xref="taxon:29430"
                     /mol_type="genomic DNA"
                     /note="type strain of Acinetobacter haemolyticus"
                     /organism="Acinetobacter haemolyticus"
                     /strain="ATCC 17906"
                     /type_material="type strain of Acinetobacter haemolyticus"
     subregion       1..13141
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000295"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..13141
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /subregion_numbers="1"
                     /tool="antismash"
     protocluster    1..10642
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[569:5642]"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      570..5642
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="siderophore"
                     /protocluster_number="1"
     cand_cluster    1..10642
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     gene            570..2354
                     /gene="acbA"
     CDS             570..2354
                     /codon_start=1
                     /gene="acbA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /product="putative acinetoferrin biosynthesis protein"
                     /protein_id="BAM09326.1"
                     /sec_met_domain="IucA_IucC (E-value: 7.3e-68, bitscore:
                     218.1, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQSLANRLALQHFVNAYTQETGKGHLLHKSQQSLQLQTFSQGLTL
                     LSIPITSIQARCFFPLSYVSCVGRHRLADLPQIIIDEKIKVFSPVAIVGLLLEELVQEA
                     AVHLDAASLVEKWIQSRDALQQFLQNREYEFDDLVKAGQSFIETEQALILGHSMHPAPK
                     SRTGFVHEDWLNFSPENKGKTQLHYWLVHQDYIAEGSATDEPISAQLKTALQWYLSESD
                     LNLLKTHAEYKLLPLHPWQARYLQGKAWFERLKQTGQLIDLGLRGWQFSPTTSIRTLAS
                     FNAPWMVKPSLSVMITNSIRVNLAKECHRGELTHRLWHSEFGQNILKQCPSLKAVNDPA
                     WIALKIDDEVINESICIFRDQPFHPQQQVTCIASLCQDHPIKPLNRFNALFAKIAKAHP
                     DAEVSEIASDWFNRFLEVSLQPLMYLYHRYGMAFESHQQNVLLELENHFPKTLWLRDNQ
                     GFYYIEEFATEILQALPELKEKAFAVGPKAFVDERFSYYFFGNTLFGIINAIGATGYIT
                     EDELLAHLTGFVEEQLQQYPESTLIQGLLFNSTLPYKGNLLTRLHELDELIAPVENQSV
                     YVQLPNPLRISQKDVSYA"
     gene            2347..3828
                     /gene="acbB"
     CDS             2347..3828
                     /codon_start=1
                     /gene="acbB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 404.4;
                     E-value: 8.3e-123)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative acinetoferrin biosynthesis protein"
                     /protein_id="BAM09327.1"
                     /transl_table=11
                     /translation="MLDFIGVGLGPFNLSLASLLQNKSSLNYVFFEQKAQFDWHAGMQL
                     PNTVLQVPFMADLVSMVDPTSPFSFLNYLRHQQRLYKFYFLEQPHIPRCEYNHYCQWVA
                     EQLDCIEYQSQVLKIEPQTIGFKVVVESNGVQQSYLCRHLVVGSGNVPYLPECLAKIQK
                     IRPQQCLHSAQYMTHADTDLHGDVVVLGSGQSAAEVFIDLFDEQQDTVNHQFDLHWFTR
                     SQGFFPMEYAPLGLEHFSPDYAQHFYDLTVQQKEHQLKQQALLYKGISAKTIREIYQKF
                     YHRSIAGQSLQTHLHSQCDLKDAEALDTQKIRLHFQHRATAQSFHLDCDFLVAATGYFT
                     PDFGFMQLLKPYIEFDHKQRWQITDDYRVVHRLNGHIFVQNQEMHSHGVGTPDLGLGAY
                     RAATIINQLLAEPLYELGNQAQTFQHFNLSQNPKICMADDKAQSNECLCENSPNKNHSI
                     FKKTEQNVMTAHPNRRGANTRTQTASVHSTYEKLI"
     gene            3825..5642
                     /gene="acbC"
     CDS             3825..5642
                     /codon_start=1
                     /gene="acbC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /product="putative acinetoferrin biosynthesis protein"
                     /protein_id="BAM09328.1"
                     /sec_met_domain="IucA_IucC (E-value: 9.3e-66, bitscore:
                     211.2, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFATLKINQQQWRAAGQRLIEMAIAEFLYEEIIEVKALSAGRYR
                     LDLGNRQYEFQGNQYLLGHWNIQEASVRDVTHSQENDQPAWNLHEFIVAMSDSSNVKPF
                     TKAYLIKEMNNTWLAEAHLFNETRLPSIAVLTEPHYKVEGMLRGHPWLIMSKGRMGFGY
                     DDYLSAAPELSPEVKVLWLAVHRDLAEYRSTEDWSACGLYQHEFDANELQQFINILQEK
                     NLDPQNYFLIPVHAWQWHQWLVPTYANEIVDQKIIELNISQDSYVPMQSIRTLCNTSNL
                     QRHYIKLPVSIFNTAVYRGLPSKRNLAAPAVTAWLKRIHQQDQDLQNTGVIFLGEVATL
                     TIHQPCFDRIDGAPYQFKELFGCLWRESVDRYVDSSHQVLSQAALLHRDISGQSILSVL
                     IQASGLSPLAWLAQFAQVSMSPLLLCLYRYGLAFSPHGENTMLVHENGVPKAMVLKDFI
                     DDINLVDEDFPELAQLPPEAALLLRHEATDLSHFIFTGLFMVHYRYICNVFLQDYPEYS
                     ELDFWQTISNTIVEFNHKHPELAERADKFAMLRPNYTKICLNRVRLFTTSYNDEAERPV
                     PVFLDPIANPVSPETLKTWAQQPRQAKVG"
     gene            5670..6308
                     /gene="acbD"
     CDS             5670..6308
                     /codon_start=1
                     /gene="acbD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203:putative siderophore biosynthesis protein (Score:
                     173.7; E-value: 1.3e-52)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative acinetoferrin biosynthesis protein"
                     /protein_id="BAM09329.1"
                     /transl_table=11
                     /translation="MKTISQQLPDYFEYFEDGTQYYLRQVKYPQDIPLLHKWMHEPHVI
                     PQWQLNKSELELQVYFDKMLADDHHRLLIVGIDGKDVGYTEIYEGKRDRLGRYYDGDDN
                     DLGWHLLFGDKSVFGKGFLRPTIRLLSFYIFEHSKAKKIVGEPDHTVKPYAAVVAELCY
                     ESQRLIPMPEKTAMLYYCFRETFYHKFGEYYQTSQQQLADRPAKILSVT"
     gene            6305..6676
                     /gene="actB"
     CDS             6305..6676
                     /codon_start=1
                     /gene="actB"
                     /product="hypothetical protein"
                     /protein_id="BAM09330.1"
                     /transl_table=11
                     /translation="MSLYINEMHILDMRFAAHVSVAEFEQWLARIQHYFEHQRNFVLIM
                     QTDENTEFPEEYRAIQGKWYKQYKQDFYQYCLGFARIAQDDEDRIRLDTPALHKAWHVP
                     YFVSVDKTEAMQWAMQRYL"
     gene            6673..7908
                     /gene="actC"
     CDS             6673..7908
                     /codon_start=1
                     /gene="actC"
                     /gene_functions="transport (smcogs) SMCOG1131:major
                     facilitator transporter (Score: 304.5; E-value: 1.4e-92)"
                     /gene_kind="transport"
                     /product="putative ferric acinetoferrin transporter"
                     /protein_id="BAM09331.1"
                     /transl_table=11
                     /translation="MNQNSLNIQKVSALSLSVVVVLYLAHALPLYFYNVALPAILRHQG
                     VDLRWIGMLSLLYIPWAFKFFWAPLIDRFYLKKLGKRKTWLLFTQIALVLGVVALALTQ
                     FDYGLGVFVIVGLWISTFAATQDIAIDGYTVETFSESEYRLGSMAQSIGVALGSMVGGA
                     ATLWLYQLYGWQTALISLAAMTALTMFAIFQIKEKSISEKIAKHPPSLIRAFKRPEMLW
                     ALALIVCYRFVEAPAMAMLNPMLIDQKWSLAEIGVLMSVIGAGIGLLAAVSAAFLLKKI
                     AATQLLIWAGWARTLIYALLGAAVLLSWFDQWHRLLGVFVVVILAIRYIAMTALYAHFM
                     QTSSKDQAGTDFTILVCFELLVYFIGGAMSGFLAKAFGYGNFYLILAAASILSVLLSQV
                     LISKAKQSKQLI"
     gene            7918..10176
                     /gene="actA"
     CDS             7918..10176
                     /codon_start=1
                     /gene="actA"
                     /gene_functions="transport (smcogs)
                     SMCOG1082:TonB-dependent siderophore receptor family
                     (Score: 250.5; E-value: 8.6e-76)"
                     /gene_kind="transport"
                     /product="putative ferric acinetoferrin receptor"
                     /protein_id="BAM09332.1"
                     /transl_table=11
                     /translation="MKVHTLSTTLTLLSLAVSAQLYAQTTEIDTTIQNNVAAEVQKPTQ
                     LAPIVMTATRSAQSIAEIAGTVQSIEQKQIGQQAAAGRKLADILAQLVPSLSPSSGTTT
                     NYGQTMRGRQVLVLIDGVAQTGSRDAARQLNSISPDSIEKIEVVSGASSIYGSGATGGI
                     INIITKKGTGDGVNFESKLGVTSGDNFKNDALAYEAYQSVGFNQGDWSGFLGAGYTKRG
                     EIQDSHGNRIGPEIAQTDRQDTETVDVNGRLSWQFTDTQKISLGAQYYNDKQDSEYGPD
                     YGPDFAVLKGNPPSLKALKGFEIDDQPFTKRYDVNTQYQNTDLLGQELNIEAYYRNEKA
                     RFYPTVLANFIPAGYYLAYQSESDIDVAGIRAAMTSKLNVADRDLKLTYGIDYDREKDK
                     QTADLYSFTHNGLKYQNTGRSYDFGPDATIKNLGAFVQGNYDLTDALNVQAGIRYQRIE
                     SDTSAFQPTVAAIQGDITGQPVGMVAAGSVKHDKTLFNLGAVYKLNDQQQVFANFSQGF
                     SLPDIQRVLRDVSAGYVVRSGNVDPITVNSYELGWRLQNDLGANLGLTTFYNTSDKVIQ
                     FKADRSVTVADTDQRIYGLEANASMPVLDQFSVGGTLSYTRGQFKDASGSWRELNAFQI
                     SPIKGTLFGEWNDGKGNSLRVQMLAVKGTDKAYEDSLVAKYDENVRPNAATKIKGYAVM
                     DVIANAKAGPGTVGFGVYNVWNADYKTVYGQAAEAVYGPISSLPAQGRTYGLSYTLKY"
     gene            10231..11457
                     /gene="actD"
     CDS             10231..11457
                     /codon_start=1
                     /gene="actD"
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 61.5; E-value: 9.1e-19)"
                     /gene_kind="transport"
                     /product="putative acinetoferrin exporter"
                     /protein_id="BAM09333.1"
                     /transl_table=11
                     /translation="MQQNFKLLAWATLANGTCFSMILPLLAPLIRELGLTEVQGGVIVS
                     AGAICMAIASILIARGEKIQTPYQLMNYGFWGMTITWAIFTAILYWGIQQTLPVMIVFA
                     LLVISRASTGGFMAMPQIGLQSYVMQHVTEEQQRSQKMAMYGAMNSLGMIVGPFLTSVL
                     LFGGILLPMWIAVILLVIFSLIITMYFKHDEGKQNTILDQKQPVKIEHSFSLKPAMPWL
                     ILGFTTYMAIVTLNMTAGFYIQDHFHLSSQQSAIYFSQCMLIVGFSLVITQILIVKVLH
                     LKLKALVLLGTFSMVSGLILSLSAIHIWMFQISYLFYGVGVASLLPAFTTGAAQSVPQT
                     AQVKMASICTATQAIGLIVAPLLSTFLYQFGIQLPFYLLLILMIAVAIYLLIISYSNQN
                     TMISNKVNS"
     CDS             11775..12332
                     /codon_start=1
                     /product="putative IS4 family transposase ORF 1"
                     /protein_id="BAM09334.1"
                     /transl_table=11
                     /translation="MTHFNELHLILNKYLKWNKSHAKCFTLIMLALIVKQTCNLSSASK
                     ALPIKCLPQSFYRRIQRFFADQYFDYRQISQLIFNIFSFDKVQLTLDRTNWKWGKRDIN
                     ILMLAIVYRGIAIPIVWTLLNKRGNSDTKERIALIQRFISIFGKDRIVNVFADREFIGE
                     KWFTWLIENDINFCIRVKKTLL"
     CDS             12431..12865
                     /codon_start=1
                     /product="putative IS4 family transposase ORF 2"
                     /protein_id="BAM09335.1"
                     /transl_table=11
                     /translation="MKLYISALRLEDGELLLVVSPMFNASAIRDYALRWEIETLFSCLK
                     GRGFNLENTRLTDPRRVKKLIAVLAIGFCWCYLTGEWQHDRKKAIKIKKHGRLSVSLFR
                     YGLDYVQMAILRLIGFGKKEEFKKVLAILRKKKPDRTRIL"
ORIGIN
        1 ctgcagttgg ttgtaaaaag ttgcagatgg caaatcccaa agatgctgag cgtttgactg
       61 gctatcttgt tggggggatt agccccttgg gtcaaaagaa acgcttaaag actgtgatcg
      121 ataaaagtgc acaagcattt gataaaattt acgttagtgg tggaaagcgt gggcttgata
      181 ttggactaaa gccgcaagat ttggcaagtt tattaaatgc ttcatttttt gacatattag
      241 atttttgatg tggggaaata ttacatttga gactatttaa aaattttata catctataaa
      301 aactattgat ggctacaagc tgatcatttt atttaatgag aattattatt atctttttgt
      361 atctttactg agcaatatcc cttattaaac aaaataaatt caatgattta gtgctgtttt
      421 tctaggttct tttatggaat tgaaatagta aatgataata attatcatta gttccatctt
      481 aactacaaac tcccttgtac ttaagatgtg tttcaggcct aaaacatttc gaaaaacaaa
      541 ttaactcttt tgaaagagga tatcgacaga tgcaatcact tgctaatcgg ttggcgttac
      601 aacatttcgt caatgcatat acgcaagaaa ctggcaaagg tcacttgctt cataaaagtc
      661 agcaatctct tcaactacag acgtttagcc aaggtttgac gctgttatca ataccgatta
      721 cctctattca agcacgttgc tttttccctt tatcttatgt gagctgtgtg gggcgacatc
      781 gcttagcaga tcttccgcaa attattatcg atgaaaaaat taaggtattt agtcctgtag
      841 caattgttgg gttgttgcta gaagaacttg ttcaagaagc cgctgttcat ctagatgctg
      901 cttcattagt tgaaaaatgg attcaaagtc gagatgcgct acaacagttt ttacaaaatc
      961 gtgaatatga atttgatgat ttagtaaaag cagggcaaag ctttattgaa acagagcaag
     1021 ctttgatttt agggcatagt atgcatcccg cgccaaaaag taggacaggc tttgttcatg
     1081 aagattggtt gaacttttct cctgaaaata aaggtaagac tcaacttcat tattggctag
     1141 tgcaccaaga ttatattgca gaaggtagtg cgactgatga acctatttca gcgcaattaa
     1201 aaaccgcgtt acagtggtat ttatctgaaa gtgatctcaa tttattaaag acacatgcgg
     1261 aatataagtt acttccttta catccatggc aagcgcgtta tttacagggc aaagcttggt
     1321 ttgaacgatt aaagcaaaca gggcaactga ttgatttggg cttgcgtggt tggcaattct
     1381 ctccaaccac ttccatacgc acattagcga gcttcaatgc accttggatg gtgaagccgt
     1441 cactttcagt gatgattacc aattctattc gagtgaattt ggccaaagaa tgtcatcgtg
     1501 gtgaattgac acatcgtctg tggcatagtg agtttgggca aaatattctt aaacagtgtc
     1561 caagtctaaa agcagtcaat gatccagctt ggatcgcttt aaaaatcgat gatgaagtga
     1621 tcaatgaaag tatttgtatt ttccgagatc aaccattcca tccacaacaa caagtcactt
     1681 gtatcgcatc tttgtgccaa gatcatccga ttaagccttt aaatcgtttt aatgccttat
     1741 ttgcaaaaat tgcgaaagcc catcctgatg ctgaagtttc agagattgct tcagattggt
     1801 ttaatcggtt cctcgaagtc agtttgcagc ctttgatgta tctataccat cgttatggta
     1861 tggcatttga gtcacatcaa caaaatgtat tattagaact cgaaaaccat tttcctaaaa
     1921 ctttatggtt acgtgataac caaggttttt attatattga agaatttgcc actgaaattc
     1981 tgcaagcact tcctgaactg aaagaaaaag cctttgcggt aggtccgaaa gcttttgttg
     2041 atgaacgttt tagttattat ttctttggca atactttgtt cgggattatt aatgccatcg
     2101 gtgcaacagg ctatattact gaagatgaat tgttagcgca tctaactgga tttgtagaag
     2161 agcaattaca gcaatatcct gagagtacct taatacaagg actactgttc aattcaacgc
     2221 tgccttataa aggcaacttg ctgacacgtt tgcatgaatt agacgagttg atcgcacctg
     2281 tagaaaatca atctgtttac gtgcaactgc caaatccgct gcgtatttca cagaaggatg
     2341 tcagttatgc ttgattttat tggagttggt ctagggcctt ttaatttaag tcttgctagt
     2401 ttgctacaaa acaaaagctc actcaattac gtgttttttg agcaaaaggc gcaatttgat
     2461 tggcatgcag gtatgcaact acctaatacg gtattacaag tgccatttat ggcagatttg
     2521 gtctcgatgg ttgatccaac cagtccattt agttttttga attatctgcg tcatcagcaa
     2581 cgtttgtata agttttactt tttagagcag ccacatattc cacgttgtga atacaaccat
     2641 tattgccaat gggttgcaga acaacttgat tgtatcgaat accagtcgca ggttctaaag
     2701 attgaacctc aaacgatagg ttttaaagta gtcgttgaat caaacggtgt tcagcaaagt
     2761 tatttatgcc gtcatttggt ggttggtagt ggcaatgtgc cttatttgcc tgaatgtttg
     2821 gcaaaaattc agaaaatccg tccacaacaa tgtcttcatt cagcacagta tatgacgcat
     2881 gccgatacag atttacatgg cgatgtggtc gtacttggtt ctggacaatc tgcagctgaa
     2941 gtgtttatcg acttatttga tgaacagcaa gatactgtca atcatcagtt tgatttgcat
     3001 tggtttacgc gttctcaggg tttcttcccg atggagtatg cgccattagg tttggaacat
     3061 tttagtccag attatgctca gcatttttat gatttgactg tgcagcaaaa ggaacatcag
     3121 ttaaagcaac aagccttgtt atacaaggga attagcgcaa aaaccattcg tgaaatttat
     3181 cagaaatttt atcaccgcag tattgcaggt caaagcttac agacacattt acatagtcaa
     3241 tgtgatttga aagatgcaga agcattggat acacaaaaaa tccgactgca tttccagcat
     3301 cgtgctacag ctcagtcttt tcatctcgac tgtgattttc ttgtagccgc gacgggttat
     3361 ttcacgcctg attttggttt tatgcagttg ctcaagccat acatagagtt tgatcataaa
     3421 cagcgttggc agattacaga cgactatcgt gttgtacatc ggctgaatgg tcatattttt
     3481 gttcaaaatc aggaaatgca tagtcatggt gtcggcacac ctgatttagg tcttggtgct
     3541 tatcgtgcag caacgatcat taatcaattg cttgctgagc ctctttatga attaggcaat
     3601 caagcgcaga cattccaaca ctttaatctc tctcaaaatc caaaaatttg tatggcagat
     3661 gacaaagcac aatcaaacga gtgcctttgc gaaaattctc ccaataaaaa ccattcaatt
     3721 ttcaagaaaa cagaacagaa cgtgatgacg gcgcatccta atcgtcgtgg tgcaaacact
     3781 cgtacacaaa ctgcttctgt acattcaaca tatgagaaac tgatatgaac tttgcaactt
     3841 taaaaattaa tcagcagcaa tggcgtgccg caggacaacg tcttattgaa atggcgattg
     3901 cagagtttct atacgaagaa attattgaag ttaaagcatt gtcagcaggg cgttatcgtt
     3961 tagatttagg caatcgtcag tatgagtttc aaggaaatca atatctactc ggacactgga
     4021 atattcagga agcttcggta cgcgatgtga ctcatagtca ggaaaatgat caacctgctt
     4081 ggaacttaca tgagttcatt gtcgcaatgt ctgacagttc taatgttaag ccatttacca
     4141 aagcgtattt gatcaaagaa atgaataata cttggcttgc agaagcacat ttgttcaatg
     4201 aaacacgttt gccaagtata gcggttttga cagagccaca ttacaaagtt gaaggcatgc
     4261 tacgtggtca tccctggctc atcatgagta aagggcgtat gggttttggt tatgatgatt
     4321 atttaagcgc tgcaccagag ctttcacctg aagttaaagt attgtggtta gccgtacatc
     4381 gtgatttggc agagtatcga agtactgaag attggagtgc ctgcggttta tatcaacatg
     4441 aatttgatgc caatgaacta cagcaattca tcaatattct ccaagaaaaa aatctagacc
     4501 cgcaaaatta ctttttaatt ccagtacacg catggcaatg gcatcaatgg ctcgttccga
     4561 cttatgccaa tgagattgtc gatcagaaaa tcattgagct gaatatcagc caagatagct
     4621 atgtgccgat gcaatcaatc cgcacattat gcaatacgtc aaacctacaa cgccattaca
     4681 ttaagttgcc tgtcagtatt tttaataccg ctgtttatcg tggattaccc tcaaagcgta
     4741 atctagcagc tccagcagtg accgcatggt taaaaagaat tcatcaacaa gatcaagact
     4801 tacaaaatac aggtgtgatt ttcttaggtg aagttgcgac tttaactatc catcagcctt
     4861 gtttcgatcg cattgatggc gcaccgtatc aatttaaaga gctgttcggt tgtttatggc
     4921 gtgaaagtgt tgatcgttat gttgattcat ctcatcaagt gttatctcaa gcagcattgt
     4981 tacaccgtga tatttcaggt caatcgatct tgagcgtgtt gatccaggca tcaggtttaa
     5041 gccctttggc ttggttagca caatttgctc aagtaagtat gagtccatta ttactttgct
     5101 tataccgcta tggtttggca ttttcaccac acggtgagaa cacgatgttg gtacatgaaa
     5161 atggagtacc aaaagctatg gtattaaaag atttcattga tgacattaat ttggtggatg
     5221 aggatttccc tgagttagct cagttaccac ctgaagcggc tttgttatta cgacatgagg
     5281 cgaccgatct aagtcatttt atcttcactg gtctgttcat ggttcattac cgctatatct
     5341 gtaatgtgtt cttgcaagac tatcctgaat attctgagct tgatttctgg cagaccattt
     5401 ccaacacaat tgttgaattt aaccacaaac atccagaact ggctgaacgt gctgataaat
     5461 tcgccatgct gcgtcctaac tacaccaaaa tttgcctaaa ccgtgtacgt ctatttacca
     5521 caagttataa cgatgaagca gagcgtcctg tgcctgtctt tcttgatccc attgcaaatc
     5581 cagttagccc agaaacattg aaaacgtggg cacagcaacc tcgccaagcg aaagtgggct
     5641 aattttattc gtcattttat aggttcgata tgaaaacaat ctctcagcaa ttaccagatt
     5701 attttgaata ctttgaagat ggaactcagt actacttacg acaagtgaaa tatccgcagg
     5761 atattccttt attgcacaaa tggatgcatg aaccacatgt gattccacag tggcagctaa
     5821 ataaatcgga actggagtta caagtttact tcgacaaaat gcttgcagat gaccatcacc
     5881 gtttattgat cgtcggaatt gatggcaaag atgtgggcta taccgaaatt tatgagggta
     5941 aacgagatcg tttaggccgt tattacgatg gtgatgacaa tgatctcggt tggcatttgc
     6001 tatttggtga caaatcagtg ttcggtaaag gttttttacg cccaactatt cgtttactca
     6061 gcttctatat ttttgagcac tctaaagcga aaaaaattgt gggtgagcca gatcataccg
     6121 tcaaacctta tgcagcagtg gtggcagagc tttgttatga aagccaacgt ttaataccga
     6181 tgcctgaaaa aacagcgatg ttgtactact gctttagaga aactttttat cacaagtttg
     6241 gggaatatta ccaaacatca caacaacagc tagcagatcg gccagccaaa atcctgagtg
     6301 ttacatgagc ttatatatca atgaaatgca tatcctagac atgcgctttg cagcgcatgt
     6361 ctcggtagca gaatttgaac aatggttagc acgaattcag cactatttcg aacatcagcg
     6421 aaattttgtg ttgatcatgc aaactgatga aaatacagaa tttccggagg aatatagagc
     6481 aatccaaggc aagtggtata aacaatataa acaagatttt taccaatatt gcttaggttt
     6541 tgcgcgtatt gctcaggatg acgaagatcg tattcgattg gatacaccag cactacacaa
     6601 agcttggcac gtcccatatt ttgtcagcgt agataaaact gaagccatgc aatgggcgat
     6661 gcagaggtat ttatgaatca aaattcatta aatattcaga aagtttcagc cttaagccta
     6721 agtgtcgtgg tggttttata cctcgcgcat gctttaccac tgtattttta caacgtggca
     6781 ttaccagcga ttctgcgcca tcaaggtgta gatttacgtt ggattggcat gttgtcgttg
     6841 ctttatattc cttgggcatt caaattcttt tgggcgcctt taattgatcg tttctactta
     6901 aaaaaactag gaaagcgtaa gacttggttg ctatttacac aaattgcact ggtgctaggt
     6961 gttgttgctt tggcattaac acagtttgat tatggcctcg gtgtatttgt cattgttggt
     7021 ttatggattt caacttttgc agcaactcaa gatattgcca ttgatggcta taccgtcgaa
     7081 accttttcag agtctgaata tcgcttagga agcatggcac aaagcatcgg cgttgcgctc
     7141 ggtagtatgg tgggtggagc agcaacttta tggctttacc agctttatgg ctggcaaact
     7201 gcattgattt ccttagccgc aatgacggca ctgactatgt ttgcgatttt ccaaatcaaa
     7261 gaaaaatcaa tttctgagaa aatcgctaaa catccaccaa gtctgattcg tgcgtttaaa
     7321 cgtccagaaa tgttatgggc tttagctttg atcgtgtgtt atcgcttcgt tgaagcacct
     7381 gcaatggcaa tgctgaatcc gatgctaatt gatcaaaagt ggtctttggc agagattgga
     7441 gtgttgatgt ctgtgatcgg tgcgggtatt ggattattag ctgctgtatc tgctgcattt
     7501 ctcttgaaaa aaatagcagc tacacaatta ctgatctggg caggctgggc acgtactttg
     7561 atttatgcct tgttgggtgc agctgttcta ctcagttggt ttgatcaatg gcacagatta
     7621 cttggtgtat ttgtagttgt cattcttgca attcgttata tcgcgatgac ggcgttatat
     7681 gcacatttca tgcagaccag ctctaaagat caagcaggaa cggattttac gattttggtc
     7741 tgttttgaat tattggttta tttcattggt ggtgcgatgt caggtttctt agctaaagcg
     7801 tttggctatg gaaattttta tttaattctc gccgctgcat ccattttaag cgttttactc
     7861 agtcaagttt tgatttctaa agcaaaacaa tcgaaacaac ttatctaggg gctacttatg
     7921 aaagttcata cactttcgac aacactaaca cttctaagct tggcagtaag tgcccagctt
     7981 tatgctcaaa caactgagat cgataccacg attcaaaata atgttgcagc agaagtccaa
     8041 aaaccaacac aacttgcgcc aattgttatg acagcaactc gttcagcaca aagtatcgct
     8101 gaaattgcag ggacagttca atcaatcgaa cagaaacaaa ttggacaaca agcggcggct
     8161 ggacgaaagt tggcagatat tctagctcaa ctggttccat cactcagccc gagtagcgga
     8221 acaaccacta attacggtca aactatgcgt ggccgtcagg tgcttgtcct tattgatggg
     8281 gttgcccaaa caggttcacg tgatgccgca cgccaactaa atagtattag ccctgattca
     8341 attgaaaaaa ttgaggtggt ttcaggtgca agtagtatct acggttccgg tgcaacaggc
     8401 ggtattatta atatcatcac aaagaaaggg actggtgatg gtgtaaattt tgaatcaaaa
     8461 cttggtgtta catctggcga taattttaaa aatgatgcac tagcttatga agcttatcaa
     8521 tcagttgggt ttaatcaagg tgattggagt ggtttcttag gggcaggcta taccaaacgt
     8581 ggtgaaatcc aagacagtca tggtaatcgc attggaccag agattgcaca aacggatcgc
     8641 caagatacag aaacggttga tgtgaatggt cgtttaagct ggcaatttac tgatacccaa
     8701 aaaataagtt tgggggctca gtattataat gacaaacaag attcagagta tggtccagat
     8761 tatggtccag acttcgcagt tttaaaaggc aatccaccga gtttaaaagc actcaaaggt
     8821 tttgaaatcg atgatcagcc attcaccaaa cgttatgatg taaatacgca atatcaaaac
     8881 acggatttac ttgggcaaga gctgaatata gaagcatatt atcgcaatga aaaagcgcgc
     8941 ttttacccga cggttttagc taactttatt cctgctggat attatttggc ttaccaatct
     9001 gagtctgata ttgatgttgc cggtattcgt gctgcaatga catcaaagtt gaatgttgct
     9061 gatcgtgatc taaaactgac ttatggtatt gattatgacc gtgagaaaga taagcaaaca
     9121 gctgatttat atagttttac ccacaatggt ctgaaatatc aaaatacagg gcggagttat
     9181 gactttggcc cagatgcaac cattaaaaac ttaggtgcat ttgttcaagg aaattatgat
     9241 ttaacggatg cattgaatgt tcaagcgggc attcgttatc aacgtattga aagcgacacc
     9301 agtgcatttc aacccactgt tgcagctatt caaggtgata tcaccggaca gccggttgga
     9361 atggtcgctg caggttctgt taaacacgac aaaacattat ttaatttagg cgctgtgtac
     9421 aaattaaatg accagcaaca agtatttgca aacttctctc aaggttttag cttaccagat
     9481 attcaacgtg tattacgcga tgtttctgct ggttatgtag ttcgatcagg caatgttgat
     9541 ccaattactg tcaatagtta cgaattgggt tggagattgc aaaatgacct tggtgcaaat
     9601 cttggattaa caacgttcta caatacttct gataaagtca tccagtttaa agctgatcgt
     9661 tctgtaactg ttgcagatac agaccaacgt atttatggtc ttgaagcgaa tgcaagcatg
     9721 ccagtattgg atcaatttag tgtcggtggg acattatctt atactcgagg tcaatttaaa
     9781 gacgcgagtg gttcttggcg agagctgaac gcttttcaaa tttccccaat caaaggaaca
     9841 ttattcggtg agtggaatga tggcaagggc aatagtctaa gagttcagat gcttgccgtg
     9901 aaaggtactg ataaagcata tgaagattcc ctcgttgcca aatatgatga aaatgttcgc
     9961 ccaaatgcgg caactaaaat caaggggtat gcagtcatgg atgtgattgc caatgccaaa
    10021 gcaggtcctg gaactgtagg ttttggtgtc tataatgttt ggaatgcaga ctataaaacg
    10081 gtatatggcc aagcggctga agcagtttat ggtccaattt ctagtctacc agctcaaggt
    10141 cgtacctacg gtctaagcta tacacttaaa tactaatcca atcataaagg catctgatta
    10201 agatgccttt tcttttgatg aatactacct atgcaacaaa attttaaatt attggcttgg
    10261 gcaactctag ccaacggtac ttgtttttca atgattttac ctttacttgc cccattaatt
    10321 cgtgagcttg gcttaacaga agtacagggc ggagtaattg tttcagcggg tgcaatttgt
    10381 atggcgattg catctattct gattgcccga ggggaaaaaa tacagactcc ttatcaatta
    10441 atgaattatg gtttctgggg catgaccatt acttgggcta tatttacagc gattctttat
    10501 tggggaatac aacaaacatt acccgtaatg atagtttttg ctttgttggt gattagtcga
    10561 gcgagtactg gtggttttat ggctatgcca caaattggtc tacaaagtta tgtcatgcaa
    10621 catgtcacag aggaacaaca acgcagtcaa aaaatggcaa tgtatggtgc gatgaatagc
    10681 ttaggtatga tcgtcggtcc atttctgacg tccgtgttat tgtttggtgg cattctattg
    10741 ccaatgtgga ttgctgttat tttgttagtg atttttagtt tgattatcac aatgtatttt
    10801 aaacatgatg agggtaaaca aaacacaata ttggatcaaa aacagcctgt aaaaatagag
    10861 cattcatttt cattaaaacc agctatgcct tggcttattt taggatttac tacctatatg
    10921 gctatcgtga cgctcaatat gactgcagga ttctatattc aagaccattt tcatttaagc
    10981 tcacaacaaa gtgcgattta tttttcccaa tgtatgctca ttgttggttt tagcttagtg
    11041 attactcaga tcctgattgt aaaagtactt catttaaaac taaaagcttt ggtattgctg
    11101 ggtacgttta gcatggttag tggacttatc ctatctttaa gtgcaatcca tatttggatg
    11161 tttcaaataa gttatttatt ttatggggtc ggggtggcaa gccttttgcc tgcatttacc
    11221 acaggggcgg ctcaatctgt tccgcaaact gctcaagtca aaatggcaag tatttgtaca
    11281 gctactcaag cgattggtct cattgtggcg cctttactga gcacttttct atatcagttc
    11341 ggcattcaat taccttttta tttactctta atattgatga ttgctgtggc gatctacttg
    11401 ttgatcatat cctattcaaa tcagaatacg atgataagca ataaggttaa ctcctaaatc
    11461 aaatatgctt gaaagacaga gaatattaaa tttttatgat tgcagtctcg taatcaattc
    11521 ttagatgatt atttttagtt ggacgtttga tctaggcgta tggatattca ttctgcagtt
    11581 tattcacatt ttctatccaa ggggacttac taagacagaa aaacataaaa acccatatat
    11641 aaaaaatgtc aatcacaata cctttcataa tgcaaatttt ttgaccaata ctataggtat
    11701 tcgctttgta cacgacaaaa aaagataact cattgaaata atggcataat acttgttttc
    11761 tgacgacgaa tatgatgaca catttcaatg agttacatct catcttaaac aaatatctaa
    11821 agtggaacaa gtcacatgca aaatgtttta cactgattat gcttgcatta attgtaaaac
    11881 agacatgtaa tctttcttct gcatctaaag ccttacccat caagtgctta ccacaatcat
    11941 tttatcgacg tatacaacgc ttctttgcag atcagtattt cgattatcgt caaatttctc
    12001 agttaatttt caatatattt tcattcgata aagtccaatt aactttggat agaactaatt
    12061 ggaaatgggg aaaacgagat attaatatct tgatgttagc catcgtctat cgtggaatag
    12121 cgatacctat tgtttggaca ttgctcaata aacgtggaaa ttcagataca aaagagcgta
    12181 ttgctttgat tcaacgcttt atctccattt ttggtaaaga tcgtattgtg aatgtgtttg
    12241 cagacagaga atttatcggt gagaaatggt ttacatggtt aattgaaaat gacattaact
    12301 tctgtatacg tgttaaaaaa actttattgt gaccaatcac ttagccaaga atcataaaat
    12361 tagtgattta tttcgtcatc ttcaagttgg tcaaactgaa tgtcgtaaac gacgtatttg
    12421 ggttggtcga gtgaaactgt atattagtgc gctacgatta gaagatggag agcttttact
    12481 tgttgtttct cctatgttta atgcttctgc tattcgtgat tatgcattac gctgggaaat
    12541 cgaaacgtta tttagttgtc tcaaaggacg tggattcaat cttgaaaata ctcgtttaac
    12601 agaccctaga cgagtcaaga aattgatagc agtgctagct atcggtttct gttggtgcta
    12661 tttaacaggt gaatggcaac atgatcggaa aaaagcgata aaaataaaga agcatggacg
    12721 actttcagta agtttatttc gctacggttt ggactatgtt caaatggcta ttctacgttt
    12781 gattggtttt ggaaaaaaag aagaatttaa gaaagtgcta gcaattttaa gaaagaaaaa
    12841 gcctgatagg acaaggatcc tatgaaattt gtcgtgtaca gagaggtatt cgataaatat
    12901 tttaaatgca tggttaaaat ttaatcattt ttatttcatt tatttacaac ttggattatc
    12961 acaaatttta ttcggtatgc taaaagatcg tgataacaat caaggagtaa taatgctgat
    13021 ttttcatgat tatcctgtcc atggggcgat ctttgatatg gatggcacaa tgtttgatac
    13081 tgagcgatta cgctttcaaa cattaaaaca agcctctcaa gaactcattg gacaggaatt
    13141 c
//
