BGC0000297: aeruginoside 126B biosynthetic gene cluster from Planktothrix agardhii NIVA-CYA 126
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Location: 1 - 31,449 nt. (total: 31,449 nt).
This entry is originally from NCBI GenBank AM071396.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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Gene details
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General
Compounds
Genes
Polyketide
NRP
Saccharide
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000297
Short description aeruginoside 126B biosynthetic gene cluster from Planktothrix agardhii NIVA-CYA 126
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP (Glycopeptide)
  • Polyketide (Other)
  • Saccharide (hybrid/tailoring)
Loci NCBI GenBank: AM071396.2
Compounds
  • aeruginoside 126B
  • aeruginoside 126A
Species Planktothrix agardhii NIVA-CYA 126 [taxonomy]
References
Chemical products information
aeruginoside 126B
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C34H54N6O9
Chemical database entries
NPAtlas
aeruginoside 126A
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C36H54N6O9
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAM59600.1
  • ORF2
 1264 - 2010 (-) hypothetical protein
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  • CAM59601.1
  • aerA
 2649 - 6899 (+) non-ribosomal peptide synthetase/polyketide synthase hybrid enzyme
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  • CAJ21198.2
  • aerB
 7116 - 11912 (+) non-ribosomal peptide synthetase
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  • CAM59602.1
  • ORF3
 11949 - 12815 (+) hypothetical protein
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  • CAJ21199.2
  • aerC
 12856 - 15066 (+) putative oxygenase
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  • CAM59603.1
  • aerD
 15167 - 15775 (+) Prephenate decarboxylase
  • Precursor biosynthesis
Activity assay
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  • CAM59604.1
  • aerE
 15822 - 16463 (+) hypothetical protein
  • Precursor biosynthesis
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  • CAM59605.1
  • aerF
 16492 - 17286 (+) putative reductase
  • Precursor biosynthesis
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  • CAM59606.1
  • aerG
 17416 - 22284 (+) non-ribosomal peptide synthetase
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  • CAM59607.1
  • aerH
 22651 - 23382 (+) putative dioxygenase
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  • CAM59608.1
  • aerI
 23429 - 24685 (-) putative glycosyltransferase
  • Tailoring (Glycosylation)
Sequence-based prediction
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  • CAM59609.1
  • ORF4
 24913 - 25602 (+) hypothetical protein
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  • CAM59610.1
  • ORF5
 26387 - 26899 (+) hypothetical protein
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  • CAM59611.1
  • ORF6
 26844 - 28130 (+) hypothetical protein
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  • CAM59612.1
  • ORF7
 28548 - 29246 (+) hypothetical protein
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  • CAM59613.1
  • ORF8
 29310 - 30470 (+) hypothetical protein
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  • CAM59614.1
  • ORF9
 30626 - >31426 (+) hypothetical protein
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Polyketide-specific information
Subclass Other
Cyclic? no
Polyketide-synthases
Genes Properties Modules
aerA Synthase subclass: Other
NRP-specific information
Subclass Glycopeptide
Cyclic? no
NRP-synthases
Gene Modules
aerA
Module 0
Modification domains: Unknown
aerB
Module 1
Specificity: leucine
Evidence for specificity:
  • Sequence-based prediction
Condensation domain type: LCL
aerG
Module 2
Specificity: 2-carboxy-6-hydroxyoctahydroindole
Evidence for specificity:
Genes encoding specified AA: aerC, aerD, aerE, aerF
Condensation domain type: DCL
Saccharide-specific information
Subclass hybrid/tailoring
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: F65XGYSSLMUEJC2Q4T3BLCPS, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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