BGC0000298: aeruginosin 98-A biosynthetic gene cluster from Microcystis aeruginosa NIES-98
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Location: 1 - 25,401 nt. (total: 25,401 nt).
This entry is originally from NCBI GenBank FJ609416.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000298
Short description aeruginosin 98-A biosynthetic gene cluster from Microcystis aeruginosa NIES-98
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: FJ609416.1
Compounds
  • aeruginosin 98-A
  • aeruginosin 98-B
  • aeruginosin 98-C
Species Microcystis aeruginosa NIES-98 [taxonomy]
References
Chemical products information
aeruginosin 98-A
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C29H45Cl1N6O9S1
Chemical database entries
NPAtlas
ChemSpider
aeruginosin 98-B
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C29H46N6O9S1
Chemical database entries
NPAtlas
PubCHEM
ChemSpider
aeruginosin 98-C
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C29H45Br1N6O9S1
Chemical database entries
NPAtlas
ChemSpider
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACM68682.1
  • aerA
 106 - 4365 (+) AerA
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  • ACM68683.1
  • aerJ
 4610 - 6487 (+) AerJ
  • Tailoring (Halogenation)
Sequence-based prediction
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  • ACM68684.1
  • aerB
 6611 - 11395 (+) AerB
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  • ACM68685.1
  • aerK
 11435 - 12478 (+) AerK
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  • ACM68686.1
  • aerD
 12472 - 13104 (+) AerD
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  • ACM68687.1
  • aerE
 13201 - 13827 (+) AerE
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  • ACM68688.1
  • aerF
 13876 - 14676 (+) AerF
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  • ACM68689.1
  • aerL
 14715 - 15659 (+) AerL
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  • ACM68690.1
  • aerG1
 15751 - 19029 (+) AerG1
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  • ACM68691.1
  • aerG2
 19068 - 20804 (+) AerG2
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  • ACM68692.1
 20865 - 21641 (+) putative oxidoreductase
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  • aerM_
 21722 - 22234 (+)
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  • ACM68693.1
 22314 - 22922 (+) hypothetical protein
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  • ACM68694.1
  • aerN
 23096 - 25090 (+) AerN
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
aerA
Module 0
Modification domains: Keto reductase
aerB
Module 1
Specificity: isoleucine
Evidence for specificity:
  • Sequence-based prediction
Condensation domain type: Unknown
aerG1
Module 2
Specificity: 2-carboxy-6-hydroxyoctahydroindole
Evidence for specificity:
Genes encoding specified AA: aerK, aerD, aerE, aerF
Condensation domain type: DCL
aerG2
Module 3
Condensation domain type: LCL
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: F65XGYSSLMUEJC2Q4T3BLCPS, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected NRP module activity
  • Updated bioactivity data
  • Updated NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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