LOCUS       BGC0000298             25401 bp    DNA     linear   BCT 30-MAR-2009
DEFINITION  Microcystis aeruginosa NIES-98 aeruginosin synthetase gene cluster,
            complete sequence.
ACCESSION   BGC0000298
VERSION     BGC0000298
KEYWORDS    .
SOURCE      Microcystis aeruginosa NIES-98
  ORGANISM  Microcystis aeruginosa NIES-98
            Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
            Chroococcales; Microcystaceae; Microcystis.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 13:20:45
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 25401
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..25401
                     /db_xref="taxon:267869"
                     /mol_type="genomic DNA"
                     /organism="Microcystis aeruginosa NIES-98"
                     /strain="NIES-98"
     misc_feature    1..25401
                     /note="aeruginosin synthetase gene cluster"
     protocluster    1..25401
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[6610:19029]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6611..19029
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..25401
                     /SMILES="NC(C(C)CC)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="neighbouring"
                     /product="NRPS"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..25401
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000298"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..25401
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     protocluster    1..24365
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[105:4365]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      106..4365
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
     cand_cluster    1..24365
                     /SMILES="NC(C(C)CC)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="2"
                     /tool="antismash"
     gene            106..4365
                     /gene="aerA"
     CDS             106..4365
                     /NRPS_PKS="Domain: CAL_domain (331-647). E-value: 2.4e-65.
                     Score: 212.0. Matches aSDomain:
                     nrpspksdomains_aerA_CAL_domain.1"
                     /NRPS_PKS="Domain: PKS_KR (991-1186). E-value: 3.8e-45.
                     Score: 145.9. Matches aSDomain:
                     nrpspksdomains_aerA_PKS_KR.1"
                     /NRPS_PKS="Domain: PCP (1322-1389). E-value: 7.1e-27.
                     Score: 85.3. Matches aSDomain: nrpspksdomains_aerA_PCP.1"
                     /codon_start=1
                     /gene="aerA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     274.6; E-value: 2.1e-83)"
                     /gene_kind="biosynthetic"
                     /note="NRPS/PKS hybrid; aeruginosin synthetase; first
                     module with adenylation, ketoreductase, and thiolation
                     domains"
                     /product="AerA"
                     /protein_id="ACM68682.1"
                     /sec_met_domain="AMP-binding (E-value: 2.4e-84, bitscore:
                     273.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 4.7e-40, bitscore:
                     127.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.7e-18, bitscore:
                     55.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTEHKNPKLNCQKLAEVFLSNPLIEDCYFMIREGELVAYIVSSG
                     AWNSEQLSSDLQSQLPDNLLPNIYVQISSLPLTDSGDVDETALKNIEIIDDHQVQETEE
                     KLGSLSDIDQVAVVMTSKKNKILPLHLSELLPLKIEKKNDHQKSETPIHLVIHTSNTQA
                     GISHGQLLEESELQTKTLAEILQKAAENYSNKGIIYIQSNGSEVFQSYQQLWEEAQQIQ
                     AGLQKQGLQAQDKVILQLSENYDIISAFWGCLLGGFIPVIISVPPSYKDFNNEIHKISQ
                     VWQLLDEPTIITNQSRQQEIKHLKQWLPNQTLRLSFIEELKTYSPHQTHISQPDDIAFF
                     NLTSGSTGIPKCISLTHKNVISRARGTNIICEHQNDDIILNWLPFDHIGSISDWNIRCV
                     ELGCQMVYVQTEYILGRPLNWLDLIAQYRITHSWAPNFAYNLINEALKKEPDQNWNLDC
                     VKFFLAAGEAVSGQAVGEFINTLHLQYNLKKTAMRPAFGMAEMGSGITYYQPTEQQPLL
                     FHTVDKSSLNSSLKRVHPEHPNGATFTDLGLPIPGISIRIVNADNSLLPEETIGHLQVK
                     GHAVSPGYYKNPEANQDAFLKDGWFKTGDLAFISNGHLVITGRSKETIIINGVNYYSHE
                     IETVVETIEEVQASYTAACAVYDPRNSTDQLALFFSAETFDHQHLAELLKKIRRKVINS
                     FGVNPEYLIPLNKTEIPKTSIGKIQRSQLTKRFGNGEFNSILKEIDILLENDQTIPDWF
                     YQKVWKPRSPVNLKPELSKYCSLIFLDCLGLGASLAEKIEGQNLPCITVLAAEEFSQIS
                     QNCYTLRPGTANHYQQLMASLSERKIILGNIIHLGTYQDYQGEISTIEQLEKAQEKGTY
                     DLLFLVQALAKIHNFNSKIQLLFVSSYSQFVIETDEIAYEKSPVLGLIKTLAQELPWLN
                     TRHVDLPLDQTEINVSYLLQELSVLSKEREIAYRNGKRLIAGLEKVNLLQHTQQELPFK
                     SGGIYLITGGLGGIGRQIAQYLLKNYQARLLLIGKTPLPEKHLWSEYLKTEDQLSLKIK
                     SLQALENLGGEVIYQAVDVANFPQVKQAVEQVKKQWQGELNGVIHLAGIYKDCLLLDET
                     QEGLSTILHSKVIGTWVLHQLLKESQGIFISFSSLASFFGGAALGSYAAANSFLESLNS
                     YQKSKNLFPSYCYSWTTWQETGISQGYQMQYITRSQGYYDMTVRQGLDSFLTSLYHNQR
                     QLIIGLDGSNSKINRFTSRSEGCQKLTAYYTRKSTVQSVNLPNHVSLKDRLGTSYQCPL
                     VLRQSLPIKDNGDIDKRQLLKELQGKENNELIAPRTEAERQVAKIWQKVLNLSQIGIHD
                     NFFELGGHSLLASQVISRLRDVFSVELSLHSLLEYPTVASLTQTIEVLNVANNSQSVSK
                     SGKVMTTASENYEEGEL"
     aSDomain        1099..2046
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aerA_CAL_domain.1"
                     /evalue="2.40E-65"
                     /label="aerA_CAL_domain.1"
                     /locus_tag="aerA"
                     /protein_end="647"
                     /protein_start="331"
                     /score="212.0"
                     /specificity="Minowa: shikimic_acid"
                     /tool="antismash"
                     /translation="SQPDDIAFFNLTSGSTGIPKCISLTHKNVISRARGTNIICEHQND
                     DIILNWLPFDHIGSISDWNIRCVELGCQMVYVQTEYILGRPLNWLDLIAQYRITHSWAP
                     NFAYNLINEALKKEPDQNWNLDCVKFFLAAGEAVSGQAVGEFINTLHLQYNLKKTAMRP
                     AFGMAEMGSGITYYQPTEQQPLLFHTVDKSSLNSSLKRVHPEHPNGATFTDLGLPIPGI
                     SIRIVNADNSLLPEETIGHLQVKGHAVSPGYYKNPEANQDAFLKDGWFKTGDLAFISNG
                     HLVITGRSKETIIINGVNYYSHEIETVVETIEEVQ"
     aSModule        1099..4272
                     /domains="nrpspksdomains_aerA_CAL_domain.1"
                     /domains="nrpspksdomains_aerA_PKS_KR.1"
                     /domains="nrpspksdomains_aerA_PCP.1"
                     /incomplete
                     /locus_tags="aerA"
                     /starter_module
                     /tool="antismash"
                     /type="pks"
     CDS_motif       1126..1176
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerA_0001"
                     /evalue="6.50E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="aerA"
                     /protein_end="357"
                     /protein_start="340"
                     /score="12.7"
                     /tool="antismash"
                     /translation="NLTSGSTGIPKCISLTH"
     CDS_motif       1801..1890
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerA_0002"
                     /evalue="1.90E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="aerA"
                     /protein_end="595"
                     /protein_start="565"
                     /score="17.1"
                     /tool="antismash"
                     /translation="PEETIGHLQVKGHAVSPGYYKNPEANQDAF"
     aSDomain        3079..3663
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aerA_PKS_KR.1"
                     /evalue="3.80E-45"
                     /label="aerA_PKS_KR.1"
                     /locus_tag="aerA"
                     /protein_end="1186"
                     /protein_start="991"
                     /score="145.9"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GIYLITGGLGGIGRQIAQYLLKNYQARLLLIGKTPLPEKHLWSEY
                     LKTEDQLSLKIKSLQALENLGGEVIYQAVDVANFPQVKQAVEQVKKQWQGELNGVIHLA
                     GIYKDCLLLDETQEGLSTILHSKVIGTWVLHQLLKESQGIFISFSSLASFFGGAALGSY
                     AAANSFLESLNSYQKSKNLFPSYCYSWTTWQE"
     CDS_motif       3085..3177
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerA_0003"
                     /evalue="4.20E-11"
                     /label="PKSI-KR_m1"
                     /locus_tag="aerA"
                     /protein_end="1024"
                     /protein_start="993"
                     /score="35.4"
                     /tool="antismash"
                     /translation="YLITGGLGGIGRQIAQYLLKNYQARLLLIGK"
     CDS_motif       3511..3597
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerA_0004"
                     /evalue="3.40E-09"
                     /label="PKSI-KR_m4"
                     /locus_tag="aerA"
                     /protein_end="1164"
                     /protein_start="1135"
                     /score="29.2"
                     /tool="antismash"
                     /translation="FISFSSLASFFGGAALGSYAAANSFLESL"
     aSDomain        4072..4272
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aerA_PCP.1"
                     /evalue="7.10E-27"
                     /label="aerA_PCP.1"
                     /locus_tag="aerA"
                     /protein_end="1389"
                     /protein_start="1322"
                     /score="85.3"
                     /tool="antismash"
                     /translation="ERQVAKIWQKVLNLSQIGIHDNFFELGGHSLLASQVISRLRDVFS
                     VELSLHSLLEYPTVASLTQTIE"
     gene            4610..6487
                     /gene="aerJ"
     CDS             4610..6487
                     /codon_start=1
                     /gene="aerJ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119:halogenase (Score: 362.4; E-value: 6.2e-110)"
                     /gene_kind="biosynthetic-additional"
                     /note="FADH2-dependent halogenase"
                     /product="AerJ"
                     /protein_id="ACM68683.1"
                     /transl_table=11
                     /translation="MKTVEFLSDLNHLGVTIWMEGDKLRYRSPQGVMTPDLLEQLKEHK
                     EELIVLLREQADNFSSETDYDVAICGGGLAGLTLARQLKLKQPNLSVVVLDKMARPLPE
                     AGFKVGESTVEVGAFYLANTLQLTDYFNNQHLSKLGLRYFFKPQETEFHKRPELGLSEF
                     HAPKSYQIDRGKLENDLRQFNIEAGIDLKENCSVKDIEFAEGLQQQHKIIYTQGSGANQ
                     KTHCIKSRWVVDAMGRRRFIQKKLGLAKPNHNNYSAVWFRVEGRFDVSNFVPASEEKWH
                     RRVPNNNRYYSTNHLCGEGYWVWLIPLSTGYTSIGIVARQDIHPLKNYHNYELAFQWLR
                     ENEPVLAAHLEGKSPEDFRKMPKYSYSSKQVFSFNRWACVGEAGLFPDPFYSPGSDSIG
                     FGNSLTTQMIELDLKGQLTPERVDDANHFYLTYHDGLAFNIQNSYNCLKNGTAMATKVI
                     WDTLAGWTFGCLMMFNSIFLDPELKMKVQQINAEFFPLSYRIQQLFRDWANQSLGRVSF
                     EFIDYLAIPFVNELRTRNLQSNKTEAEIIEAYRASLKLLEEFAQVIFQIALEDTRPELL
                     PKINEHPWLNAWAISLDASKWETDGLFSPKSEPRNLHSIKKQYLEAINR"
     gene            6611..11395
                     /gene="aerB"
     CDS             6611..11395
                     /NRPS_PKS="Domain: Condensation_LCL (72-369). E-value:
                     5.4e-120. Score: 391.7. Matches aSDomain:
                     nrpspksdomains_aerB_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (538-938). E-value:
                     1.4e-116. Score: 381.4. Matches aSDomain:
                     nrpspksdomains_aerB_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1046-1114). E-value: 1.3e-24.
                     Score: 78.1. Matches aSDomain: nrpspksdomains_aerB_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1124-1429). E-value:
                     1.6e-144. Score: 474.4. Matches aSDomain:
                     nrpspksdomains_aerB_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1434-1588). E-value: 1.3e-42.
                     Score: 137.1. Matches aSDomain:
                     nrpspksdomains_aerB_TIGR01720.1"
                     /NRPS_PKS="Domain: NRPS-COM_Cterm (1571-1592). E-value:
                     9e-10. Score: 30.0. Matches aSDomain:
                     nrpspksdomains_aerB_NRPS-COM_Cterm.1"
                     /codon_start=1
                     /gene="aerB"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     359.8; E-value: 3.2e-109)"
                     /gene_kind="biosynthetic"
                     /note="NRPS module; aeruginosin synthetase; second module
                     with adenylation, condensation, thiolation, and
                     epimerization domains"
                     /product="AerB"
                     /protein_id="ACM68684.1"
                     /sec_met_domain="Condensation (E-value: 1.1e-85, bitscore:
                     277.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 9.9e-128, bitscore:
                     416.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-16, bitscore:
                     51.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVAEFLSYLNSLDIKLWLEEEKLKYQAPQGAMTPEIKQEIGTRK
                     PEILTFLRSATTPSKPLESVINSVARTEDLPLSFAQQRMWFLYQMDQQNSAYNEALTIR
                     LTGRLNIDILEQTINAIIQRHESLRTTFPVVEGKPIQKIAPSLKIKLLVVNLKDIPQEQ
                     IDKQIIEELQKPFDLTQSPLLRCTLFDLGYENYILVNVFHHIIIDGWSKGILFKELSKF
                     YQAFLSNSTVNLPELPIQYADFAVWQRQWLQGEILENQLNYWKKQLTGAPPLLELPTDK
                     PRPATPNFRGHSISFQIDSELTENLKLLSQKSGVTLFMTLLAALNTLLFRYSGQDDILI
                     GTPTANRNRQEIEPLIGFFVNTLVLRNSLEGNPTFSGLLQQARNVVLEAYANQDVPFEQ
                     VVDGLEIERSLSYNPLFQVMFAMQNAPLNALELPDLKAQYLAVENQRIKFDLSLVLEEI
                     ETEKGAYLEGFWEYDSDLLTPERINRMVGHFQTLLKGIVANPQQTIGELPLLTESEKQQ
                     LLVEWNQTQTSYPDHYCIHQLFEEQVVKTPDAIAVIDGEQSLTYEQLNQKANQIARYLQ
                     KLGVKPDQLIGICVERLPLMIIGFLGILKAGGAYVPLDTSYPEERLESIINDAEIKILL
                     TQQHLIKKLPTTVNQLICLEQDEDPIKQQSKQNPLSHVNAENLAYVIYTSGSTGKPKGV
                     AIPHRGVTRLVCNTNYIYLKPTDRMAQVSNPSFDAATFEIWGALIHGAQLIGVDKDRVL
                     SPEKFVHFLQKYQITILFLTTALFNQLVQTIPHAFQSLRYLLFGGEAVDPQWVKESLNK
                     GTAQNLLHVYGPTESTTFTSWYLIKNIPSEATTIPIGRPLANTEIYILDPYLQPVPIGV
                     KGELHIGGDGLARCYLNRPDLTEQKFIPNPFSQDSSARLYKTGDIVRYLADGNIEFIGR
                     IDHQVKIRGFRIELGEIEAVLFQHPQVKDGIVIAREDLLGIKRLYAYVVPKDKQLTQPE
                     LRIFLQEKLPNYMIPAFLIFLDAFTLNQNGKIDRSVLPRPEIDVNELENYLLPSTEKET
                     ILAQIWQEVLGQNQISINENFFELGGDSIIAIQIVAKANQVGLQITPKQLFSHQTIAQL
                     ATVAETTAITEIDQGLVTGEVPLTPIQKWFFEQNWPERHHFNQSILLEVPNNLQPDLLK
                     QTISKLLYHHDALRLRFVQKGEQWQQNHSDDCNNFAFEKVDLSHLSYHEQLTKMAEISE
                     VQQRVLNLEEGPLMAVVFFALGESGKMLIVIHHLAVDGISWRIILEDFVTIYQQLETQK
                     PLQLPPKTSSFKTWAEELQNYAKTPEFYAQFKYWLNRDFSSVSPLPVDVQGDAQSNIVA
                     HAKTVSFTLTEEQTRLLLQEVPQAYNTQINDILLTALVQAFGRWTGNYKLLLDMEGHGR
                     ENVIESVNLSRTVGWFTSIFPVFLTLENLHHPGECLKSIKEQLRQIPNRGFDYGIGYYL
                     SSDLTIQSPLKNYPKAQVSFNYLGQFTSHQIGEIGWKLSQESTGSIHSPLGQRSHLIAI
                     HGIVVDGQLDMEWQYSENFHHQTTIKNLAAAYRDSLESLINHCLSVEGGYTPSDFPDAD
                     LNQAELDELLSELDF"
     aSDomain        6827..7717
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aerB_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.40E-120"
                     /label="aerB_Condensation_LCL.1"
                     /locus_tag="aerB"
                     /protein_end="369"
                     /protein_start="72"
                     /score="391.7"
                     /tool="antismash"
                     /translation="EDLPLSFAQQRMWFLYQMDQQNSAYNEALTIRLTGRLNIDILEQT
                     INAIIQRHESLRTTFPVVEGKPIQKIAPSLKIKLLVVNLKDIPQEQIDKQIIEELQKPF
                     DLTQSPLLRCTLFDLGYENYILVNVFHHIIIDGWSKGILFKELSKFYQAFLSNSTVNLP
                     ELPIQYADFAVWQRQWLQGEILENQLNYWKKQLTGAPPLLELPTDKPRPATPNFRGHSI
                     SFQIDSELTENLKLLSQKSGVTLFMTLLAALNTLLFRYSGQDDILIGTPTANRNRQEIE
                     PLIGFFVNTLVLRNSL"
     aSModule        6827..11374
                     /complete
                     /domains="nrpspksdomains_aerB_Condensation_LCL.1"
                     /domains="nrpspksdomains_aerB_AMP-binding.1"
                     /domains="nrpspksdomains_aerB_PCP.1"
                     /domains="nrpspksdomains_aerB_Epimerization.1"
                     /domains="nrpspksdomains_aerB_TIGR01720.1"
                     /locus_tags="aerB"
                     /monomer_pairings="Ile -> D-Ile"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       6842..6871
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0001"
                     /evalue="3.50E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="aerB"
                     /protein_end="87"
                     /protein_start="77"
                     /score="10.0"
                     /tool="antismash"
                     /translation="SFAQQRMWFL"
     CDS_motif       6893..7009
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0002"
                     /evalue="1.30E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="aerB"
                     /protein_end="133"
                     /protein_start="94"
                     /score="59.3"
                     /tool="antismash"
                     /translation="SAYNEALTIRLTGRLNIDILEQTINAIIQRHESLRTTFP"
     CDS_motif       7214..7279
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0003"
                     /evalue="1.50E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="aerB"
                     /protein_end="223"
                     /protein_start="201"
                     /score="33.5"
                     /tool="antismash"
                     /translation="FHHIIIDGWSKGILFKELSKFY"
     CDS_motif       7328..7366
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0004"
                     /evalue="1.80E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="aerB"
                     /protein_end="252"
                     /protein_start="239"
                     /score="20.3"
                     /tool="antismash"
                     /translation="QYADFAVWQRQWL"
     CDS_motif       7592..7615
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0005"
                     /evalue="3.50E+01"
                     /label="NRPS-E7"
                     /locus_tag="aerB"
                     /protein_end="335"
                     /protein_start="327"
                     /score="-1.3"
                     /tool="antismash"
                     /translation="LLFRYSGQ"
     CDS_motif       7619..7708
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0006"
                     /evalue="6.40E-18"
                     /label="C5_LCL_267-296"
                     /locus_tag="aerB"
                     /protein_end="366"
                     /protein_start="336"
                     /score="57.1"
                     /tool="antismash"
                     /translation="DILIGTPTANRNRQEIEPLIGFFVNTLVLR"
     CDS_motif       7757..7876
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0007"
                     /evalue="2.40E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="aerB"
                     /protein_end="422"
                     /protein_start="382"
                     /score="71.4"
                     /tool="antismash"
                     /translation="RNVVLEAYANQDVPFEQVVDGLEIERSLSYNPLFQVMFAM"
     CDS_motif       8054..8086
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0008"
                     /evalue="1.50E+01"
                     /label="NRPS-E5"
                     /locus_tag="aerB"
                     /protein_end="492"
                     /protein_start="481"
                     /score="-0.9"
                     /tool="antismash"
                     /translation="INRMVGHFQTL"
     aSDomain        8225..9424
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aerB_AMP-binding.1"
                     /evalue="1.40E-116"
                     /label="aerB_AMP-binding.1"
                     /locus_tag="aerB"
                     /protein_end="938"
                     /protein_start="538"
                     /score="381.4"
                     /specificity="substrate consensus: Ile"
                     /tool="antismash"
                     /translation="FEEQVVKTPDAIAVIDGEQSLTYEQLNQKANQIARYLQKLGVKPD
                     QLIGICVERLPLMIIGFLGILKAGGAYVPLDTSYPEERLESIINDAEIKILLTQQHLIK
                     KLPTTVNQLICLEQDEDPIKQQSKQNPLSHVNAENLAYVIYTSGSTGKPKGVAIPHRGV
                     TRLVCNTNYIYLKPTDRMAQVSNPSFDAATFEIWGALIHGAQLIGVDKDRVLSPEKFVH
                     FLQKYQITILFLTTALFNQLVQTIPHAFQSLRYLLFGGEAVDPQWVKESLNKGTAQNLL
                     HVYGPTESTTFTSWYLIKNIPSEATTIPIGRPLANTEIYILDPYLQPVPIGVKGELHIG
                     GDGLARCYLNRPDLTEQKFIPNPFSQDSSARLYKTGDIVRYLADGNIEFIGRIDHQVKI
                     R"
     CDS_motif       8411..8452
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0009"
                     /evalue="4.90E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="aerB"
                     /protein_end="614"
                     /protein_start="600"
                     /score="19.6"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
     CDS_motif       8645..8704
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0010"
                     /evalue="1.60E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="aerB"
                     /protein_end="698"
                     /protein_start="678"
                     /score="32.8"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGVAIPH"
     CDS_motif       9212..9301
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0011"
                     /evalue="9.90E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="aerB"
                     /protein_end="897"
                     /protein_start="867"
                     /score="49.8"
                     /tool="antismash"
                     /translation="PIGVKGELHIGGDGLARCYLNRPDLTEQKF"
     CDS_motif       9389..9454
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0012"
                     /evalue="1.90E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="aerB"
                     /protein_end="948"
                     /protein_start="926"
                     /score="39.0"
                     /tool="antismash"
                     /translation="FIGRIDHQVKIRGFRIELGEIE"
     aSDomain        9749..9952
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aerB_PCP.1"
                     /evalue="1.30E-24"
                     /label="aerB_PCP.1"
                     /locus_tag="aerB"
                     /protein_end="1114"
                     /protein_start="1046"
                     /score="78.1"
                     /tool="antismash"
                     /translation="ETILAQIWQEVLGQNQISINENFFELGGDSIIAIQIVAKANQVGL
                     QITPKQLFSHQTIAQLATVAETT"
     aSDomain        9983..10897
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aerB_Epimerization.1"
                     /evalue="1.60E-144"
                     /label="aerB_Epimerization.1"
                     /locus_tag="aerB"
                     /protein_end="1429"
                     /protein_start="1124"
                     /score="474.4"
                     /tool="antismash"
                     /translation="TGEVPLTPIQKWFFEQNWPERHHFNQSILLEVPNNLQPDLLKQTI
                     SKLLYHHDALRLRFVQKGEQWQQNHSDDCNNFAFEKVDLSHLSYHEQLTKMAEISEVQQ
                     RVLNLEEGPLMAVVFFALGESGKMLIVIHHLAVDGISWRIILEDFVTIYQQLETQKPLQ
                     LPPKTSSFKTWAEELQNYAKTPEFYAQFKYWLNRDFSSVSPLPVDVQGDAQSNIVAHAK
                     TVSFTLTEEQTRLLLQEVPQAYNTQINDILLTALVQAFGRWTGNYKLLLDMEGHGRENV
                     IESVNLSRTVGWFTSIFPVFLTLE"
     CDS_motif       9998..10027
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0013"
                     /evalue="3.00E-04"
                     /label="NRPS-E1"
                     /locus_tag="aerB"
                     /protein_end="1139"
                     /protein_start="1129"
                     /score="13.7"
                     /tool="antismash"
                     /translation="LTPIQKWFFE"
     CDS_motif       10073..10162
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0014"
                     /evalue="4.60E-04"
                     /label="C2_starter_024-063"
                     /locus_tag="aerB"
                     /protein_end="1184"
                     /protein_start="1154"
                     /score="12.9"
                     /tool="antismash"
                     /translation="EVPNNLQPDLLKQTISKLLYHHDALRLRFV"
     CDS_motif       10367..10429
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0015"
                     /evalue="1.10E-10"
                     /label="NRPS-E2"
                     /locus_tag="aerB"
                     /protein_end="1273"
                     /protein_start="1252"
                     /score="33.7"
                     /tool="antismash"
                     /translation="LIVIHHLAVDGISWRIILEDF"
     CDS_motif       10838..10888
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0016"
                     /evalue="2.70E-08"
                     /label="NRPS-E5"
                     /locus_tag="aerB"
                     /protein_end="1426"
                     /protein_start="1409"
                     /score="25.9"
                     /tool="antismash"
                     /translation="NLSRTVGWFTSIFPVFL"
     aSDomain        10913..11374
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aerB_TIGR01720.1"
                     /evalue="1.30E-42"
                     /label="aerB_TIGR01720.1"
                     /locus_tag="aerB"
                     /protein_end="1588"
                     /protein_start="1434"
                     /score="137.1"
                     /tool="antismash"
                     /translation="GECLKSIKEQLRQIPNRGFDYGIGYYLSSDLTIQSPLKNYPKAQV
                     SFNYLGQFTSHQIGEIGWKLSQESTGSIHSPLGQRSHLIAIHGIVVDGQLDMEWQYSEN
                     FHHQTTIKNLAAAYRDSLESLINHCLSVEGGYTPSDFPDADLNQAELDEL"
     CDS_motif       10931..10993
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0017"
                     /evalue="1.70E-07"
                     /label="NRPS-E6"
                     /locus_tag="aerB"
                     /protein_end="1461"
                     /protein_start="1440"
                     /score="23.6"
                     /tool="antismash"
                     /translation="IKEQLRQIPNRGFDYGIGYYL"
     CDS_motif       11039..11068
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerB_0018"
                     /evalue="1.70E-02"
                     /label="NRPS-E7"
                     /locus_tag="aerB"
                     /protein_end="1486"
                     /protein_start="1476"
                     /score="8.0"
                     /tool="antismash"
                     /translation="AQVSFNYLGQ"
     aSDomain        11324..11386
                     /aSDomain="NRPS-COM_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aerB_NRPS-COM_Cterm.1"
                     /evalue="9.00E-10"
                     /label="aerB_NRPS-COM_Cterm.1"
                     /locus_tag="aerB"
                     /protein_end="1592"
                     /protein_start="1571"
                     /score="30.0"
                     /tool="antismash"
                     /translation="PSDFPDADLNQAELDELLSEL"
     gene            11435..12478
                     /gene="aerK"
     CDS             11435..12478
                     /codon_start=1
                     /gene="aerK"
                     /note="putative isopentenyl pyrophosphate isomerase;
                     probably involved in Choi moiety formation"
                     /product="AerK"
                     /protein_id="ACM68685.1"
                     /transl_table=11
                     /translation="MPSPNLPSEIENRKSEHLRVCIEKDVEFQQLTSGLEKYRFTHCCL
                     PELDRSDIELGTTFLGKSLKAPILISSMTGGTELAHLVNTRLATVAQRYGLAMGVGSQR
                     IALEQPELAPTFAVRSLAPDILLLANLGAVQLNYGCGLEDCLKLVELLEADALILHLNP
                     LQEWVQSGGDSNFKGLLAKIQQICAQLPVPVIAKEVGNGISAVMAKQLIEAGVAAIDVA
                     GAGGTSWAKVESQRAKDNRQRHLGQVFADWGLPTAECITAIRSMNSTIPLIASGGLKNG
                     LDLAKSIALGADLGGLARPFLVAAIESEAAVDELVKFLIAELEIVLFCTGNPNLSTLKT
                     SGALKPC"
     gene            12472..13104
                     /gene="aerD"
     CDS             12472..13104
                     /codon_start=1
                     /gene="aerD"
                     /note="similar to BacA; bacilysin synthesis; involved in
                     Choi moiety formation"
                     /product="AerD"
                     /protein_id="ACM68686.1"
                     /transl_table=11
                     /translation="MLKFSMELCYPQLDIKTLSVGTLGPKETSSEQTLNYLISQWKLQQ
                     ISVNSHLFDSFTDLKESLLQNQIDLALVPHAYEKINDFYMEPRFKLGFIFTYPTPVYGL
                     AKRKNEEIVLENCTLVTHPAPLPLLPYLLPGDLNQNKIKIKFVNSTSVAAIQVKQGLAD
                     LAITNENALREYDLEFISQYGKIEMSWSLFHKKENTMIQSIYLPVHT"
     gene            13201..13827
                     /gene="aerE"
     CDS             13201..13827
                     /codon_start=1
                     /gene="aerE"
                     /note="similar to BacB; bacilysin synthesis; involved in
                     Choi moiety formation"
                     /product="AerE"
                     /protein_id="ACM68687.1"
                     /transl_table=11
                     /translation="MSEFFPIPKPIKLNPHVELEVFQCQDTIFQLYVIAPNAKLESHQH
                     PESQIGMVFSAELELYIKDLIKPLRPLQDVYIADGNIPHGAFNPLSEPMIGFDLKRITS
                     ALPSEDVLLTLSNNQDKITHLPCQSVKGSWFEIVMMKIPSGYSIPPHQGEQEEIGFILN
                     GKLEISIENEGQFLEYGQIYYAPSKVLKKGYNSSKQDINLIKILI"
     gene            13876..14676
                     /gene="aerF"
     CDS             13876..14676
                     /NRPS_PKS="Domain: PKS_KR (8-129). E-value: 5e-10. Score:
                     31.4. Matches aSDomain: nrpspksdomains_aerF_PKS_KR.1"
                     /codon_start=1
                     /gene="aerF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     191; E-value: 4.1e-58)"
                     /gene_kind="biosynthetic-additional"
                     /note="short-chain dehydrogenase/reductase; involved in
                     Choi moiety formation"
                     /product="AerF"
                     /protein_id="ACM68688.1"
                     /transl_table=11
                     /translation="MDLGLKDKVALITGSSAGIGFTIAEKLAEEGCHLIICGRNSQRLE
                     QAYQSLAQAYPVQEILSLVADVHQAQDSEQLIQDSLNQYGKIDILVNNSEGANFADNLI
                     ENLSDEDWLNVFQGKLMGYIRLTNLVLPIMKKQHWGRIVNIIGTSGKEPSPRLVKSGVV
                     NAALMNFTKSVARQTAPYNVLINSVNPGVIDTPRHREYLEIYAKKEGTTPDLIRERILK
                     TIPMNRIGTTEEFANLVVFLASECASYITGITIPIDGGLSSSAF"
     aSDomain        13900..14262
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aerF_PKS_KR.1"
                     /evalue="5.00E-10"
                     /label="aerF_PKS_KR.1"
                     /locus_tag="aerF"
                     /protein_end="129"
                     /protein_start="8"
                     /score="31.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VALITGSSAGIGFTIAEKLAEEGCHLIICGRNSQRLEQAYQSLAQ
                     AYPVQEILSLVADVHQAQDSEQLIQDSLNQYGKIDILVNNSEGANFADNLIENLSDEDW
                     LNVFQGKLMGYIRLTNL"
     CDS_motif       13906..13995
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerF_0001"
                     /evalue="7.20E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="aerF"
                     /protein_end="40"
                     /protein_start="10"
                     /score="15.4"
                     /tool="antismash"
                     /translation="LITGSSAGIGFTIAEKLAEEGCHLIICGRN"
     gene            14715..15659
                     /gene="aerL"
     CDS             14715..15659
                     /codon_start=1
                     /gene="aerL"
                     /note="putative sulfotransferase; probably involved in
                     sulfatation of the Choi moiety"
                     /product="AerL"
                     /protein_id="ACM68689.1"
                     /transl_table=11
                     /translation="MNSESKSQMLDKFVPYYPTKDTRNFPIFSYLINNVNIWRLKHKFK
                     QELEQPSVILVYQMGKVGSANLYLAIKRTFPEKAVYHVHNLNPEIVAKIWDKIHLTQPY
                     YLSTIEHSLTTKYLSDHLETIKDKDKIRIIAGVRDPIARNISWFFQIIDCESAFPQFFR
                     KFKEGLITIDDMVNCFWSQKFVFSKQFDWFELELKSVFGIDISEIDFPKEKGYTIVEFP
                     DKKIELLLFKLEKLDSCLQEMTQAFFGIEKLDYQKLKLINVDLEYHRIYENFKNSLTFS
                     DEYLEKIYDQPLVSHFYTDEEINKFKLKWSSQR"
     gene            15751..19029
                     /gene="aerG1"
     CDS             15751..19029
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (5-37). E-value: 7.7e-21.
                     Score: 64.9. Matches aSDomain:
                     nrpspksdomains_aerG1_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (14-316). E-value:
                     3.1e-115. Score: 376.3. Matches aSDomain:
                     nrpspksdomains_aerG1_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (479-881). E-value: 2e-105.
                     Score: 344.6. Matches aSDomain:
                     nrpspksdomains_aerG1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (991-1056). E-value: 6.9e-27. Score:
                     85.3. Matches aSDomain: nrpspksdomains_aerG1_PCP.1"
                     /codon_start=1
                     /gene="aerG1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     340.7; E-value: 2.7e-103)"
                     /gene_kind="biosynthetic"
                     /note="NRPS module; aeruginosin synthetase; third module
                     with adenylation, condensation, and thiolation domains;
                     similar to Planktothrix NIVA CYA 126-8 AerG"
                     /product="AerG1"
                     /protein_id="ACM68690.1"
                     /sec_met_domain="Condensation (E-value: 2e-77, bitscore:
                     250.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.2e-117, bitscore:
                     381.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.2e-18, bitscore:
                     56.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTPQQSRVSKKDIESIYPLSPMQQGMLFHSLYNPESKTYLSQIQ
                     ITLQGNLDINAFQQAWQKVVDRHSILRTCFAWKKTKQPLQVVRKNVTLPWFNQDWRSHS
                     PAEQETKFQELLTSDKEQYFELDKVPLLRCHLIQVEDQKYEFIHTGHHILLDGWATAIL
                     LKEVFDFYAGLINYQPVNLPTPRPYQDYINWLQQQDQTEAERFWRQNLQGFTSPTPLVV
                     DKPLNPLVTQSKNYLHQKSKLSPEITSRLKLLAQEYRLTLSTLIQGAWALLLHHYSSES
                     DIVFGATVSGRPPNFTGIESMVGMFLNTLPVRIQIESQLELLTWFQQLQQEHLEREQYS
                     YSSLIDIQKWSEIPSPHSVFESFVVFENLPFSDNDSDNLGGLQVGEMQDYGNADYPLTV
                     IVTPGEALSIKIIYPQERFENDTIERILGHFKTLLEGIAINPHRRIQDLPLLTEAERQL
                     LLIEWNQTAPQKPLKHCVHELFEQQTLKTPSAIAVVFQEQQLTYEELNESANQLAHYLQ
                     KIGVSFQSLVGICLERSVNMVIAVLAVLKVGCVCVPLDPTYPQERLSYILQDTQIKTLL
                     TQKDCQSLLNSETISQRILLDEQGSEIALEPKTNLDNPVSLKDLAYIIYSSGSTGVPKG
                     IMILHQSLTNIIEHHQAKMSPERNFLQFAPFNFDVSYHEMFAAWCLGGTLFIVPEDARL
                     DLAKISQLLANNPIHKAILPVTLLQQLIETYSEETYLFANLREIISAGEQLQITPTMIS
                     VFKKLEHCTLYNYYGPTEADIVTSYTFDPNPELWPKYIPIGKPAINVQVYILNSHLQPV
                     PIGVTGELYVAGGGLARGYFNNPQLTQEKFIANPFSDNSLLYKTGDLARYLPNGDIEYL
                     GRIDDVVKVRGYRIELGEVETILNQHPQIAQAIATVQGKTAREKYLAAYFIPRPGETVN
                     QVELRHFLENWLPDYMIPSAFVVMESFQLSPNGKVDRKVLPIPDKNPLSLTQNYVAPRT
                     AIEEVLAGIWAEILEVERVGIEDDFFLLGGHSLKAIQLISKIRQTLEIEISVRQLFNHS
                     TIGQLTQVMIELVGNEGLLNEIAVTVQEISQLSPEEVQALLSQN"
     aSDomain        15766..15861
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aerG1_NRPS-COM_Nterm.1"
                     /evalue="7.70E-21"
                     /label="aerG1_NRPS-COM_Nterm.1"
                     /locus_tag="aerG1"
                     /protein_end="37"
                     /protein_start="5"
                     /score="64.9"
                     /tool="antismash"
                     /translation="QSRVSKKDIESIYPLSPMQQGMLFHSLYNPES"
     aSDomain        15793..16698
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aerG1_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="3.10E-115"
                     /label="aerG1_Condensation_DCL.1"
                     /locus_tag="aerG1"
                     /protein_end="316"
                     /protein_start="14"
                     /score="376.3"
                     /tool="antismash"
                     /translation="ESIYPLSPMQQGMLFHSLYNPESKTYLSQIQITLQGNLDINAFQQ
                     AWQKVVDRHSILRTCFAWKKTKQPLQVVRKNVTLPWFNQDWRSHSPAEQETKFQELLTS
                     DKEQYFELDKVPLLRCHLIQVEDQKYEFIHTGHHILLDGWATAILLKEVFDFYAGLINY
                     QPVNLPTPRPYQDYINWLQQQDQTEAERFWRQNLQGFTSPTPLVVDKPLNPLVTQSKNY
                     LHQKSKLSPEITSRLKLLAQEYRLTLSTLIQGAWALLLHHYSSESDIVFGATVSGRPPN
                     FTGIESMVGMFLNTLPVRIQI"
     aSModule        15793..18918
                     /complete
                     /domains="nrpspksdomains_aerG1_Condensation_DCL.1"
                     /domains="nrpspksdomains_aerG1_AMP-binding.1"
                     /domains="nrpspksdomains_aerG1_PCP.1"
                     /locus_tags="aerG1"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       15802..15840
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerG1_0001"
                     /evalue="7.80E-06"
                     /label="C1_dual_004-017"
                     /locus_tag="aerG1"
                     /protein_end="30"
                     /protein_start="17"
                     /score="18.4"
                     /tool="antismash"
                     /translation="YPLSPMQQGMLFH"
     CDS_motif       15868..15981
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerG1_0002"
                     /evalue="1.90E-17"
                     /label="C2_DCL_024-062"
                     /locus_tag="aerG1"
                     /protein_end="77"
                     /protein_start="39"
                     /score="55.5"
                     /tool="antismash"
                     /translation="YLSQIQITLQGNLDINAFQQAWQKVVDRHSILRTCFAW"
     CDS_motif       16201..16263
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerG1_0003"
                     /evalue="1.30E-09"
                     /label="C3_DCL_135-156"
                     /locus_tag="aerG1"
                     /protein_end="171"
                     /protein_start="150"
                     /score="30.5"
                     /tool="antismash"
                     /translation="HHILLDGWATAILLKEVFDFY"
     CDS_motif       16309..16347
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerG1_0004"
                     /evalue="5.80E-04"
                     /label="C4_DCL_171-183"
                     /locus_tag="aerG1"
                     /protein_end="199"
                     /protein_start="186"
                     /score="12.3"
                     /tool="antismash"
                     /translation="PYQDYINWLQQQD"
     CDS_motif       16594..16689
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerG1_0005"
                     /evalue="1.10E-18"
                     /label="C5_DCL_263-294"
                     /locus_tag="aerG1"
                     /protein_end="313"
                     /protein_start="281"
                     /score="59.7"
                     /tool="antismash"
                     /translation="DIVFGATVSGRPPNFTGIESMVGMFLNTLPVR"
     CDS_motif       16738..16860
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerG1_0006"
                     /evalue="2.80E-15"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="aerG1"
                     /protein_end="370"
                     /protein_start="329"
                     /score="48.7"
                     /tool="antismash"
                     /translation="QQEHLEREQYSYSSLIDIQKWSEIPSPHSVFESFVVFENLP"
     aSDomain        17188..18393
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aerG1_AMP-binding.1"
                     /evalue="2.00E-105"
                     /label="aerG1_AMP-binding.1"
                     /locus_tag="aerG1"
                     /protein_end="881"
                     /protein_start="479"
                     /score="344.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEQQTLKTPSAIAVVFQEQQLTYEELNESANQLAHYLQKIGVSFQ
                     SLVGICLERSVNMVIAVLAVLKVGCVCVPLDPTYPQERLSYILQDTQIKTLLTQKDCQS
                     LLNSETISQRILLDEQGSEIALEPKTNLDNPVSLKDLAYIIYSSGSTGVPKGIMILHQS
                     LTNIIEHHQAKMSPERNFLQFAPFNFDVSYHEMFAAWCLGGTLFIVPEDARLDLAKISQ
                     LLANNPIHKAILPVTLLQQLIETYSEETYLFANLREIISAGEQLQITPTMISVFKKLEH
                     CTLYNYYGPTEADIVTSYTFDPNPELWPKYIPIGKPAINVQVYILNSHLQPVPIGVTGE
                     LYVAGGGLARGYFNNPQLTQEKFIANPFSDNSLLYKTGDLARYLPNGDIEYLGRIDDVV
                     KVR"
     CDS_motif       17218..17256
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerG1_0007"
                     /evalue="4.10E+01"
                     /label="C3_dual_135-156"
                     /locus_tag="aerG1"
                     /protein_end="502"
                     /protein_start="489"
                     /score="-2.3"
                     /tool="antismash"
                     /translation="AIAVVFQEQQLTY"
     CDS_motif       17374..17415
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerG1_0008"
                     /evalue="5.50E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="aerG1"
                     /protein_end="555"
                     /protein_start="541"
                     /score="13.4"
                     /tool="antismash"
                     /translation="LAVLKVGCVCVPLD"
     CDS_motif       17611..17670
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerG1_0009"
                     /evalue="9.60E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="aerG1"
                     /protein_end="640"
                     /protein_start="620"
                     /score="27.4"
                     /tool="antismash"
                     /translation="AYIIYSSGSTGVPKGIMILH"
     CDS_motif       18187..18276
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerG1_0010"
                     /evalue="1.40E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="aerG1"
                     /protein_end="842"
                     /protein_start="812"
                     /score="52.5"
                     /tool="antismash"
                     /translation="PIGVTGELYVAGGGLARGYFNNPQLTQEKF"
     CDS_motif       18358..18423
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerG1_0011"
                     /evalue="2.80E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="aerG1"
                     /protein_end="891"
                     /protein_start="869"
                     /score="35.4"
                     /tool="antismash"
                     /translation="YLGRIDDVVKVRGYRIELGEVE"
     aSDomain        18724..18918
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aerG1_PCP.1"
                     /evalue="6.90E-27"
                     /label="aerG1_PCP.1"
                     /locus_tag="aerG1"
                     /protein_end="1056"
                     /protein_start="991"
                     /score="85.3"
                     /tool="antismash"
                     /translation="EEVLAGIWAEILEVERVGIEDDFFLLGGHSLKAIQLISKIRQTLE
                     IEISVRQLFNHSTIGQLTQV"
     gene            19068..20804
                     /gene="aerG2"
     CDS             19068..20804
                     /NRPS_PKS="Domain: Condensation_LCL (38-338). E-value:
                     1e-90. Score: 295.6. Matches aSDomain:
                     nrpspksdomains_aerG2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: PCP (511-575). E-value: 1.1e-19. Score:
                     62.3. Matches aSDomain: nrpspksdomains_aerG2_PCP.1"
                     /codon_start=1
                     /gene="aerG2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     334.3; E-value: 2.3e-101)"
                     /gene_kind="biosynthetic-additional"
                     /note="NRPS module (truncated); aeruginosin synthetase;
                     probable fourth module with condensation and thiolation
                     domains; similar to Planktothrix NIVA CYA 126-8 AerG"
                     /product="AerG2"
                     /protein_id="ACM68691.1"
                     /sec_met_domain="Condensation (E-value: 6.2e-66, bitscore:
                     212.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.9e-17, bitscore:
                     52.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNNSQDQQKLLKLLLQKKGISFKKVNTIPKRQSSNSELIPISLT
                     QLELWFFAQFYPENCIYNLPCIYRIEGLLNVPALEESLREIVKRHESLRTTFTCIDGKV
                     FQKITDDPVFDFSILDLQRLSEVEQKKETQRLLSAEINRSFDLEKDSLFCSKIIKFAEN
                     NYLLIMTIHHIIADGWSLNILTKELGILYEAFCLNKPSPLPELPIQYGDFSLWQWQSIK
                     DNSWQSQLNFWKKHIGINPPILKLPTDYPRTTAQPVEAAIHHFLISQNLTDALKSLSHQ
                     EKATLYMTLLAALKILLFYYTEQTEIIIGGVAANRNQPETQDLIGLMVQFLPLYTHVEG
                     QANFRDLLHQVKEMSLEFDAYQEIPFITLVEKLKPIRDTQYALFHQVIFLFQNAPKQDL
                     KFINLTVTDELLKMDIEPHSAENDLTISLEETEQGMKGAFVYKADLFTAETITQMEQYF
                     QQLLKNIVTDPNKTISDLCPFSESVSFSDNTSPLSLSINEIKSNDLPHNLTRETMVNIW
                     QEVLELEEISVNDNFFDLGGDSQKVIQVIDKIGKILKINCTLRDFFENPTVARLITTFK
                     NK"
     aSDomain        19182..20081
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aerG2_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.00E-90"
                     /label="aerG2_Condensation_LCL.1"
                     /locus_tag="aerG2"
                     /protein_end="338"
                     /protein_start="38"
                     /score="295.6"
                     /tool="antismash"
                     /translation="LIPISLTQLELWFFAQFYPENCIYNLPCIYRIEGLLNVPALEESL
                     REIVKRHESLRTTFTCIDGKVFQKITDDPVFDFSILDLQRLSEVEQKKETQRLLSAEIN
                     RSFDLEKDSLFCSKIIKFAENNYLLIMTIHHIIADGWSLNILTKELGILYEAFCLNKPS
                     PLPELPIQYGDFSLWQWQSIKDNSWQSQLNFWKKHIGINPPILKLPTDYPRTTAQPVEA
                     AIHHFLISQNLTDALKSLSHQEKATLYMTLLAALKILLFYYTEQTEIIIGGVAANRNQP
                     ETQDLIGLMVQFLPLYTHV"
     aSModule        19182..20792
                     /domains="nrpspksdomains_aerG2_Condensation_LCL.1"
                     /domains="nrpspksdomains_aerG2_PCP.1"
                     /incomplete
                     /locus_tags="aerG2"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       19248..19358
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerG2_0001"
                     /evalue="1.30E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="aerG2"
                     /protein_end="97"
                     /protein_start="60"
                     /score="56.1"
                     /tool="antismash"
                     /translation="IYNLPCIYRIEGLLNVPALEESLREIVKRHESLRTTF"
     CDS_motif       19578..19643
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerG2_0002"
                     /evalue="1.20E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="aerG2"
                     /protein_end="192"
                     /protein_start="170"
                     /score="33.7"
                     /tool="antismash"
                     /translation="IHHIIADGWSLNILTKELGILY"
     CDS_motif       19692..19724
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerG2_0003"
                     /evalue="2.30E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="aerG2"
                     /protein_end="219"
                     /protein_start="208"
                     /score="10.8"
                     /tool="antismash"
                     /translation="QYGDFSLWQWQ"
     CDS_motif       19983..20069
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerG2_0004"
                     /evalue="8.20E-08"
                     /label="C5_LCL_267-296"
                     /locus_tag="aerG2"
                     /protein_end="334"
                     /protein_start="305"
                     /score="24.7"
                     /tool="antismash"
                     /translation="EIIIGGVAANRNQPETQDLIGLMVQFLPL"
     CDS_motif       20145..20210
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerG2_0005"
                     /evalue="1.10E-03"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="aerG2"
                     /protein_end="381"
                     /protein_start="359"
                     /score="11.3"
                     /tool="antismash"
                     /translation="AYQEIPFITLVEKLKPIRDTQY"
     aSDomain        20601..20792
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aerG2_PCP.1"
                     /evalue="1.10E-19"
                     /label="aerG2_PCP.1"
                     /locus_tag="aerG2"
                     /protein_end="575"
                     /protein_start="511"
                     /score="62.3"
                     /tool="antismash"
                     /translation="TMVNIWQEVLELEEISVNDNFFDLGGDSQKVIQVIDKIGKILKIN
                     CTLRDFFENPTVARLITTF"
     CDS             20865..21641
                     /NRPS_PKS="Domain: PKS_KR (11-174). E-value: 7.7e-12.
                     Score: 37.3. Matches aSDomain:
                     nrpspksdomains_ACM68692.1_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     222.8; E-value: 8e-68)"
                     /gene_kind="biosynthetic-additional"
                     /note="orf1"
                     /product="putative oxidoreductase"
                     /protein_id="ACM68692.1"
                     /sec_met_domain="adh_short (E-value: 7.3e-35, bitscore:
                     110.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNHLFDLTGKVAIITGAARGIGRVLAQGLAQAGAKVVIGDINQV
                     GAEQTVQLIQEAGGEAIAIQTDVRQRQACQNLINQTVANYGQLDIMVCNAGVEILKNTD
                     ELEEFEWDQVINVDLKGYFNCAQLATKQMIKQGTKGSIIMNSSICAFVAVPKSSGAYSA
                     AKGGVNQLVKSLAVELASHKIRVNAFAPGYMNNMMEGTEGLRSTSDEMDELYTRIPMKR
                     TGDLEELIGPVVFLASEASSYVTGAILMVDGGYTAI"
     aSDomain        20898..21386
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACM68692.1_PKS_KR.1"
                     /evalue="7.70E-12"
                     /label="ACM68692.1_PKS_KR.1"
                     /locus_tag="ACM68692.1"
                     /protein_end="174"
                     /protein_start="11"
                     /score="37.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAIITGAARGIGRVLAQGLAQAGAKVVIGDINQVGAEQTVQLIQE
                     AGGEAIAIQTDVRQRQACQNLINQTVANYGQLDIMVCNAGVEILKNTDELEEFEWDQVI
                     NVDLKGYFNCAQLATKQMIKQGTKGSIIMNSSICAFVAVPKSSGAYSAAKGGVNQLVKS
                     "
     CDS_motif       20904..20978
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACM68692.1_0001"
                     /evalue="4.00E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="ACM68692.1"
                     /protein_end="38"
                     /protein_start="13"
                     /score="19.5"
                     /tool="antismash"
                     /translation="IITGAARGIGRVLAQGLAQAGAKVV"
     gene            21722..22234
                     /gene="aerM'"
                     /pseudo=""
     CDS             21722..22234
                     /NRPS_PKS="Domain: Condensation_LCL (38-158). E-value:
                     8.1e-28. Score: 89.1. Matches aSDomain:
                     nrpspksdomains_aerM__Condensation_LCL.1"
                     /codon_start=1
                     /gene="aerM_"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_kind="biosynthetic-additional"
                     /note="similar to Microcystis PCC 7806 aerM; AerM';
                     fragment of NRPS module"
                     /pseudo=""
                     /sec_met_domain="Condensation (E-value: 1.5e-23, bitscore:
                     73.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKMNHNSQDKQKLLKLLLQKKGIGVKTNTIPTRNPSQLVPLSFS
                     QERLWFLYQLEANGYTYNMPFRFQIDGNLDVNIFRKALETIMQRHELLRTCFQEVDKTP
                     RQIIKLKIQLNLPLLDLLQELSHLYEAFDKNNLILDQISLFNTVIFPFGKDNSYFAYFT
                     KSGFLTQ"
     aSDomain        21836..22195
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aerM__Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="8.10E-28"
                     /label="aerM__Condensation_LCL.1"
                     /locus_tag="aerM_"
                     /protein_end="158"
                     /protein_start="38"
                     /score="89.1"
                     /tool="antismash"
                     /translation="LVPLSFSQERLWFLYQLEANGYTYNMPFRFQIDGNLDVNIFRKAL
                     ETIMQRHELLRTCFQEVDKTPRQIIKLKIQLNLPLLDLLQELSHLYEAFDKNNLILDQI
                     SLFNTVIFPFGKDNSY"
     CDS_motif       21848..21877
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerM__0001"
                     /evalue="1.30E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="aerM_"
                     /protein_end="52"
                     /protein_start="42"
                     /score="11.1"
                     /tool="antismash"
                     /translation="SFSQERLWFL"
     CDS_motif       21902..22012
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aerM__0002"
                     /evalue="9.60E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="aerM_"
                     /protein_end="97"
                     /protein_start="60"
                     /score="56.6"
                     /tool="antismash"
                     /translation="TYNMPFRFQIDGNLDVNIFRKALETIMQRHELLRTCF"
     CDS             22314..22922
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 112.3;
                     E-value: 3.9e-34)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative acetyltransferase; orf2"
                     /product="hypothetical protein"
                     /protein_id="ACM68693.1"
                     /transl_table=11
                     /translation="MFNLKHQLYLLISKFLEKQKRIEKHKKLSDNATFHSSVKFIGKCI
                     NYREDKTLIQIGENTVIIGELAIFPFGGKIEIGRNCYIGEGTRIRSATSIKIGNEVIIS
                     DDVSIYDTDAHSLNYVLRQKEFMEVLILNNLIKDAKDVDIQSAPVVIEDHVWIGFNVAI
                     LKGVTIGKGAIIGAGSVVTKDVEPFTIVAGNPAKIIKRL"
     gene            23096..25090
                     /gene="aerN"
     CDS             23096..25090
                     /codon_start=1
                     /gene="aerN"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 114.3; E-value:
                     1.2e-34)"
                     /gene_kind="transport"
                     /note="ABC-type transporter; similar to other NRPS related
                     ABC transporters"
                     /product="AerN"
                     /protein_id="ACM68694.1"
                     /transl_table=11
                     /translation="MNVAEKTSDSINLKEDVRTFNQSLQEFLRFIQVYWYPKEHQDRAF
                     SQIIRSWGMLVLLFLLLVGLVGLNAFNSFVFRDLITFTEARDAEKLTHLVIIYAITLGS
                     MTFFGGLSKFLKKLIALDWYQWINSSILQKYFKNRAYYQINFKGDIENPDQRLSQEIQP
                     IARTTMDFLTTCVEKVMEMLVFIAILWSISKTISIVLLVYTIIGNIVATYITQQLNKVN
                     KQQLEIEGTYKYAMTHVRTHAESIAFFRGEEKELNIIQRKFNQVIKIMIERINWERTQE
                     FFNRGYQSIVQIFPFLIVSPLYISGEIEFGQVNQVSYCCYFFSTALSVLVDEFGRSREF
                     INYIERLEEFYQALEGVSEQTNPVNTIKVIEDNNLAFDDVTLQTPDAAKVIVEHLSLSV
                     EPGEGLLIVGPSGRGKSSLLRAISGLWNTGTGHLVRPPLDDLLFLPQRPYIILGNLREQ
                     LIYPQTTTEMSESQLKEILQEVNLQDVLNRIKNFDEEVDWENILSLGEQQRLAFARLFV
                     NQPDFVILDEATSALDLKNEDHLYKQLQQTGKTFISVGHRESLFNYHQRVLELSEDSTW
                     RLMRMADYHPSTAIATHSNNEQTVDETIEIVSEINNQDNFTHQEMQKLTNYSLSTIKNK
                     ARRGQTIVANDGMSYRYDKTLDIAKWVRV"
ORIGIN
        1 aaatctcttg actatcctag cccgaatgag atatgctctg atagctcaga cagtgatgca
       61 attcaggctt gaatcggccc gtacacagaa ccgaggattt taggcatgag gacggaacac
      121 aaaaatccaa aattaaattg tcagaaatta gcagaagtct ttttatcaaa tcccttaatt
      181 gaagattgct attttatgat acgagagggt gaattagtcg cctatattgt ttcctctgga
      241 gcttggaatt ctgaacaatt gtcctccgat ttacagtctc agttaccgga caatcttcta
      301 cctaatatct atgtgcagat ttccagttta cccttaaccg atagcggtga tgtcgatgaa
      361 actgcattaa agaatattga aattatcgat gatcatcaag ttcaggaaac agaagaaaaa
      421 ctaggctctt tgtcagatat tgatcaagtc gctgtcgtca tgacttctaa aaagaacaaa
      481 attttacccc tacatctatc agaattattg cccttaaaaa tagagaaaaa aaatgatcat
      541 caaaaatctg aaaccccgat tcatctggtg attcacactt ctaacactca agctggaatc
      601 agtcacggac agcttttaga agaatctgaa cttcaaacta aaaccttggc agaaatcctc
      661 caaaaagctg ctgaaaatta ttcaaataaa gggattattt atattcaatc taatggatca
      721 gaagtttttc aatcctatca acaattatgg gaagaagctc aacaaataca agccggatta
      781 caaaagcagg gtttacaagc tcaagataaa gtaattcttc agctatcgga aaactatgat
      841 atcatttccg cattttgggg gtgtctttta ggaggattta ttcctgttat tatttcagtg
      901 ccacccagct ataaagattt taataatgaa attcataaaa tttctcaagt ttggcagttg
      961 ttagatgaac ctactattat cacaaatcaa tcccgtcagc aagagataaa acatttaaaa
     1021 caatggttgc ctaatcaaac cttaagattg agttttattg aagaattaaa aacttattct
     1081 ccccatcaga ctcatattag tcaaccggat gatattgcgt tctttaatct aacatcaggc
     1141 agtacaggaa taccgaaatg tatctcatta acccataaaa atgtcatctc tcgtgcgcga
     1201 ggaacaaaca tcatttgtga acatcaaaac gacgatatta ttcttaattg gcttcctttt
     1261 gatcatattg gaagtatttc agactggaat attcgctgtg tcgagttagg atgccaaatg
     1321 gtttatgttc aaactgaata tatattaggt cgtcctttga attggttaga tttaattgct
     1381 caatatcgaa ttacccatag ttgggctcct aattttgctt ataatttgat caatgaagct
     1441 ttaaaaaaag aaccggatca aaattggaat ttagattgtg tcaaattctt tttggcagcg
     1501 ggtgaagccg tttctggtca agcagttgga gaatttatta acacccttca tcttcaatat
     1561 aatctgaaaa aaacggcgat gcgtcctgct tttgggatgg cagaaatggg gtcaggaatt
     1621 acctattatc agccgacaga acaacagcca ttactctttc atacggttga taaatcctcc
     1681 ttgaattctt ccttaaaacg agtccatcct gaacatccca atggtgcaac ctttacggat
     1741 ttaggattac ccatcccagg aatatcgatt agaattgtta atgctgataa ttccctatta
     1801 ccagaagaaa ccattggtca tttacaagtt aaaggtcatg cagtttcacc cgggtattat
     1861 aaaaacccag aagcaaatca agacgctttc ttaaaagatg gctggtttaa gacaggagat
     1921 ttagcattta ttagtaacgg tcatttagtt atcactggaa gaagtaaaga aaccattatt
     1981 attaatggag tgaattatta tagccatgaa attgaaactg tagtggaaac tattgaagaa
     2041 gtacaagcgt cctacacagc cgcttgtgct gtttatgatc ctaggaatag taccgatcaa
     2101 ttagctttat tttttagtgc agaaaccttt gatcaccagc atctagcgga acttctgaaa
     2161 aagattagac gaaaagtaat taacagtttt ggcgttaatc ctgaatattt aatcccctta
     2221 aataaaactg aaattcctaa aacttccatt ggtaaaattc agcgatcgca attaacaaaa
     2281 cggtttggaa atggagaatt taattctatt ttaaaagaaa tagatatttt attagaaaac
     2341 gatcaaacca ttcctgattg gttttaccag aaagtttgga aacctcgatc tccagttaac
     2401 ttaaaacccg aactttccaa gtattgtagt ttaatttttc tggattgctt gggtttagga
     2461 gcatctttag cagaaaaaat cgaagggcaa aacttaccct gtatcacggt tttagcagcg
     2521 gaagaatttt ctcaaatcag tcaaaattgc tatactctaa gacccgggac agccaatcat
     2581 tatcaacagt taatggcatc tttatccgag cgaaaaatta ttcttggcaa tattattcat
     2641 ctggggactt atcaagacta tcagggagaa atttcaacaa ttgaacagtt agaaaaagca
     2701 caagaaaaag gaacctatga tttattattc ctagttcaag ctttagctaa aattcataat
     2761 tttaactcaa aaattcaatt gctatttgtt tccagttata gtcaatttgt catagaaacc
     2821 gatgaaattg cctatgaaaa atctccagtt ttaggactga tcaaaaccct agctcaagaa
     2881 cttccttggt taaatactcg tcatgttgat ttacctctgg atcaaaccga aattaatgtc
     2941 agttatctgc tgcaagaact atcggtttta tccaaggaaa gagaaattgc ctatcgcaac
     3001 gggaaacgtt taatcgcagg tttggaaaaa gtcaatttac ttcaacacac ccaacaggaa
     3061 ttacccttta aatcaggggg aatttatctg attactggag gactaggggg gattggcaga
     3121 caaattgctc agtatttgct caaaaattat caagctcgtt tactgttaat tggaaaaaca
     3181 cctttaccag aaaaacacct ttggagtgag tacctcaaaa ccgaagatca attatcctta
     3241 aaaataaaaa gtctccaagc tttagaaaac cttgggggag aagtaattta tcaagcggta
     3301 gatgtggcta atttccctca agttaaacag gctgtagaac aggtgaaaaa acaatggcaa
     3361 ggagaactta atggggtgat tcatctggct ggaatttaca aagattgttt acttctggac
     3421 gaaactcaag agggtttatc gacaattctt cactctaaag taataggaac ttgggtttta
     3481 catcaacttc tcaaagaatc tcagggaatt tttattagtt tttcttcctt ggctagtttt
     3541 tttggaggag cggctttggg ttcctatgcg gcggctaata gtttccttga gtctttgaac
     3601 agctatcaaa aatctaagaa tttgttcccc agttattgtt atagttggac aacttggcaa
     3661 gaaactggga ttagccaggg ttatcagatg caatacataa cccgatctca agggtattat
     3721 gatatgacag tgcggcaagg tttagactca tttctaacga gtttatatca caaccaaaga
     3781 caattaataa tcggtttaga tgggagtaat agcaagatta atcgtttcac atctaggtct
     3841 gaaggatgcc aaaagttaac ggcttattac acccgtaaat ctacagttca atcggtcaat
     3901 ctacctaatc atgttagtct aaaagatcga ttgggaacgt cctatcaatg tcccctagtt
     3961 ctgcgacaat ctctgcctat taaggataat ggagacattg ataagcggca attactcaag
     4021 gaactccaag gcaaagaaaa taacgaattg atagcaccca gaacggaagc tgaacgtcaa
     4081 gttgctaaga tttggcaaaa ggtgttaaat ctatctcaaa ttggaattca tgacaatttc
     4141 tttgaactag gaggacattc cttgctggct agtcaagtca tctctcgttt acgcgatgtt
     4201 ttctcggtag aattgtcttt gcacagttta ttagaatacc ccaccgttgc cagtttaact
     4261 caaacgattg aggtgcttaa tgtagccaac aatagtcaaa gtgtatccaa aagtggtaaa
     4321 gttatgacaa cagcctcaga aaattatgaa gaaggagaat tatgaaaata gcttaactaa
     4381 aatttaagct tttcagatcc attttggaaa aaaatgtaaa aaattgtatc catcactaaa
     4441 atttatcatc cagaatatgc tataaatagt ttcggtttaa aacagtcttt ttgtggagta
     4501 tgtaagcggt tgctcccata gcaactgact ttaacaataa ccaccgactc cccgccattg
     4561 ataatttttg tttggtctat agtatttagt ctttgaggga cttaaattta tgaaaacagt
     4621 tgaattttta tcggatctga atcatttagg tgtgacaatt tggatggaag gggataagct
     4681 gcgctatcgt tctcctcaag gtgttatgac tcccgattta ctcgaacaat tgaaagagca
     4741 taaagaagaa ctcatcgttt tattgcgtga acaagctgac aattttagtt cggaaacaga
     4801 ctatgatgtg gcaatttgtg gcggtggatt agcgggttta accttagcga gacagttaaa
     4861 acttaaacaa cctaatcttt ccgttgttgt tcttgataaa atggctcgtc ctttacccga
     4921 agctggtttt aaagtggggg aatcaaccgt tgaagttggt gctttttatt tagcaaatac
     4981 gctgcagtta accgattatt ttaacaatca acatttatct aaactgggat tacgttattt
     5041 tttcaaacct caagaaactg aatttcataa aagacctgaa ctgggattat cagagtttca
     5101 tgctcctaaa tcttatcaaa ttgatcgggg taaattagaa aatgatttac gccaatttaa
     5161 tattgaagca ggaattgacc ttaaagaaaa ttgttcggtt aaagacatcg agtttgctga
     5221 agggctacag caacagcata aaattattta tactcaaggc agtggagcga atcaaaaaac
     5281 tcattgtatt aaatcccgat gggttgtcga tgcgatgggt cgtcgtcgat ttatacagaa
     5341 gaaactcggt ttagcgaaac ctaatcataa taattacagt gcggtttggt tccgagttga
     5401 gggtcgtttt gatgtcagca attttgtgcc agccagtgaa gaaaaatggc atcggcgtgt
     5461 tcctaataac aaccgttatt attctacaaa tcatttatgc ggtgaaggat actgggtttg
     5521 gttaattcct ttatctacgg gttataccag tattggcatt gtggctcgtc aagatattca
     5581 cccgttaaaa aattatcata actatgagtt agcctttcag tggttaaggg aaaatgaacc
     5641 cgttttagcg gctcatttag aaggtaaatc cccagaagac tttagaaaga tgccgaaata
     5701 tagctactcc tcgaaacaag tcttttcctt taatcgttgg gcttgtgtcg gtgaagcagg
     5761 cctatttcct gatccgtttt attcccccgg ttcagatagt attggttttg gcaattcttt
     5821 aaccactcaa atgattgaac ttgaccttaa aggtcaacta actcccgaaa gagttgacga
     5881 tgcgaatcac ttttatttaa cctatcacga tgggttagcc tttaatattc aaaattccta
     5941 taactgtctt aaaaatggga cagcgatggc tacaaaagtc atctgggata ccttagctgg
     6001 atggacattc ggttgcttaa tgatgtttaa ttccatcttc cttgacccgg aacttaagat
     6061 gaaagttcaa cagattaatg cagaattttt ccctctttcc tatcgaatac aacaactatt
     6121 ccgagattgg gcaaatcaat ccctgggtcg ggttagcttt gaatttattg attacttagc
     6181 aatccccttt gtaaatgaac tgcgaaccag gaatttacaa tctaataaaa ccgaagctga
     6241 aatcatagaa gcttatcgag ccagcttaaa attattagaa gaatttgctc aagtcatttt
     6301 tcaaattgcc ttagaggata ccagacccga actgttacct aaaattaacg aacacccctg
     6361 gttaaatgct tgggcaatta gtttggatgc cagtaaatgg gagactgatg ggctgttttc
     6421 gcctaagagc gaacctcgta atttacacag cattaaaaaa caatatttag aggcaataaa
     6481 ccgataaaaa tagacgaatc aagttgatta tatctctaac agtagctcta gcttgagcta
     6541 ctgtactcag ccaaatatca cccccattcc aaaaatacca gaacattaat taaggaaaag
     6601 gatactattg atgaaagtcg cagaattttt atcttactta aatagtttag acatcaagct
     6661 ttggcttgag gaagaaaagt taaaatatca agctccccaa ggagcaatga caccagaaat
     6721 taagcaagaa atcgggacaa gaaaaccaga aattctcact tttttaagaa gtgcaacaac
     6781 accatctaaa ccccttgaat ccgtaattaa tagcgttgcc cgaactgaag atttacccct
     6841 atcttttgct caacagagaa tgtggtttct ctatcagatg gatcagcaaa attcggctta
     6901 taatgaagct ctaaccatcc gtttaacggg acgcttaaac attgatattt tagagcaaac
     6961 gattaatgct attattcaac gccatgagag cttacggaca acctttccag tggttgaagg
     7021 aaaacctatt caaaaaattg ctccatctct gaagattaaa ttattagttg ttaatttaaa
     7081 agatatcccc caagagcaaa ttgacaaaca gattattgaa gaactacaaa aaccctttga
     7141 tttaacccaa tctcccctat tacgatgtac tctgtttgat ctgggatatg aaaattatat
     7201 tttagtcaac gtcttccatc atattattat cgatggttgg tcaaaaggca ttttatttaa
     7261 agaattatct aaattttatc aagcattttt atccaattca accgtaaatt tacccgaatt
     7321 acctatacag tatgcggatt ttgcggtatg gcaaagacaa tggttacaag gtgaaatctt
     7381 agaaaatcag ttaaattatt ggaaaaaaca attaacgggc gctcctcctt tattagaact
     7441 tccaaccgat aaaccccgtc cagctactcc caattttcga ggtcatagta tctcgtttca
     7501 aattgactca gaactcacag aaaacctgaa acttttgagc caaaagtcgg gggtgacttt
     7561 atttatgacc ttactggctg ctttaaacac tttactcttt cgttatagtg gtcaagatga
     7621 tattttaatc gggacaccca ccgccaaccg aaaccgacaa gaaattgaac ctttgattgg
     7681 gttttttgtc aatactttag tgctgcggaa ttccctagaa ggaaatccga ctttttcggg
     7741 attattacag caagctcgca atgttgtttt agaagcgtat gccaatcaag atgtcccctt
     7801 tgagcaagtg gttgatgggt tagaaatcga acgaagttta agttataatc ccttatttca
     7861 ggtcatgttt gcgatgcaaa atgcccccct caatgcttta gaattacctg atttaaaggc
     7921 tcaatattta gccgttgaaa accagagaat taaatttgat ctcagcttag ttttagagga
     7981 aatcgaaacc gaaaaaggag cttatttaga aggtttttgg gaatatgata gcgacctatt
     8041 aactcctgaa agaattaacc gcatggtggg tcatttccaa actttattaa aggggattgt
     8101 agccaatcct cagcaaacca tcggggaatt accgttactg actgaatcgg aaaaacagca
     8161 attattagta gaatggaatc aaactcaaac gtcttatcct gatcattact gtattcatca
     8221 gttatttgaa gaacaggttg ttaaaacacc tgatgctata gcggtcatcg atggtgaaca
     8281 atccctcacc tatgaacagt taaatcaaaa agccaatcag attgcccgtt atttacaaaa
     8341 attaggggtt aaaccagatc aattaattgg gatttgtgtc gagcgattac ccttaatgat
     8401 tattggattt ttaggaatct taaaagctgg aggagcttat gtaccactgg acacaagcta
     8461 tcccgaagaa cgacttgaat ctatcataaa tgatgctgaa atcaaaattt tattaacgca
     8521 acagcacctc atcaaaaaac taccaacaac agtcaatcaa ttgatttgtt tagaacaaga
     8581 tgaagaccca attaaacaac aaagtaaaca gaatcctctc agtcatgtta acgctgagaa
     8641 tttagcctac gtcatctata cttcaggttc tacaggtaaa cctaaaggag ttgctattcc
     8701 ccatcgagga gtgactcgtt tagtctgtaa tactaactat atatatttaa aaccaactga
     8761 tagaatggct caggtttcta atccttcttt tgatgccgct acttttgaaa tttggggggc
     8821 gctgatacat ggcgcacagt taataggagt agataaagat agagttcttt ctcctgaaaa
     8881 atttgttcat tttctccaaa aatatcaaat tactatttta ttcttaacga cagcgttatt
     8941 taatcagtta gttcagacta ttccccatgc ttttcaaagc ttaagatatt tactttttgg
     9001 tggcgaagca gttgatcctc aatgggtcaa agaatccctt aataaaggaa ccgctcaaaa
     9061 tttacttcat gtttatgggc caacagaaag cacaactttt acctcttggt atttaattaa
     9121 aaatattcct tcagaagcta caactattcc aattggtcgt cctttagcta atacagaaat
     9181 ttatattctt gatccctatt tgcaacctgt tcctattggt gttaaaggcg aattgcatat
     9241 tggtggtgat ggtttagccc gttgttatct caatcgtcct gacttaactg aacaaaaatt
     9301 tattcccaat ccttttagtc aagattcgtc agcacgtctg tataaaacag gtgatatagt
     9361 acgctattta gccgatggga atattgaatt tattggacgg attgatcatc aggtaaaaat
     9421 cagaggtttt agaattgaat taggcgaaat agaagccgtt ttatttcagc atcctcaagt
     9481 caaagatgga attgttatcg ccagagaaga tctacttgga atcaagcgtt tgtatgctta
     9541 tgttgttccg aaagataaac aactcactca gccagaatta cgaatttttc tccaagaaaa
     9601 gctgcccaat tatatgattc ctgctttctt gattttctta gatgctttta ctcttaatca
     9661 gaatggaaaa attgatcgca gtgttttacc tagaccagaa attgatgtta atgaattaga
     9721 aaattatctt cttcctagta ccgagaaaga aacaattcta gcccaaattt ggcaggaagt
     9781 tttagggcaa aatcaaatta gtattaatga gaatttcttt gaattaggag gcgattcaat
     9841 tatcgccatt caaattgtcg ctaaagctaa tcaagtggga ttacaaatta ctcctaaaca
     9901 attatttagt catcaaacta tcgctcaatt agccaccgta gcggagacaa ctgctatcac
     9961 tgaaattgac cagggattag ttacaggtga agtcccgtta acgccgattc aaaaatggtt
    10021 ttttgaacaa aactggcccg aacgtcatca ctttaatcaa tctatcttgt tagaggttcc
    10081 caataatcta caaccagatt tattaaaaca aactatttct aaattactct atcaccatga
    10141 tgccttgcgg ttacggtttg tgcaaaaagg ggaacaatgg caacaaaatc acagcgatga
    10201 ttgcaataat ttcgcttttg aaaaggtgga tttatcccat ctatcttacc atgaacaatt
    10261 gaccaagatg gcagaaattt ctgaggttca acaacgggta ctgaatttag aggaaggccc
    10321 cttaatggcg gtggttttct tcgccttggg tgagagtgga aaaatgttaa ttgtaattca
    10381 tcatttagca gtagatggaa tttcttggcg gattatcctc gaagatttcg ttacgattta
    10441 ccagcaatta gaaacccaaa agcctctgca acttcctcct aaaaccagtt cttttaaaac
    10501 ttgggctgag gaactgcaaa actatgcgaa aaccccagag ttttacgctc aattcaagta
    10561 ttggctaaac cgtgattttt catccgtttc tcctcttcct gtagatgttc agggggatgc
    10621 ccaatctaac attgttgccc atgccaaaac ggtctctttc accttaaccg aagaacaaac
    10681 ccgcttactc ttacaggagg ttccgcaagc ttataacacc caaattaatg atattctatt
    10741 gaccgcttta gtccaagctt ttggccgttg gacaggaaat tataagcttt tgcttgacat
    10801 ggaaggtcat ggaagagaga atgtaattga atccgtgaat ttatctcgaa ctgtgggttg
    10861 gtttaccagt attttccccg tctttttgac cttagaaaat cttcaccatc cgggtgagtg
    10921 tctcaagtcc attaaagagc agttaagaca aattccgaat cgaggatttg attatggaat
    10981 tggatattat ctgagttcag atttaacgat tcaatccccg ttaaaaaact atccaaaagc
    11041 tcaagtcagc tttaattatt taggtcaatt taccagccat caaatcggcg agataggctg
    11101 gaaattatct caagaatcca ctggttccat tcatagtcct ttgggacaac gttcccattt
    11161 aattgcgatt catggaattg tggttgatgg gcaacttgat atggaatggc aatatagtga
    11221 aaattttcat catcaaacaa cgatcaaaaa tttagccgct gcttatcgag attctttaga
    11281 aagcctgatt aaccattgtt tatcggtaga aggaggctat actccatcgg attttcccga
    11341 tgcggatctt aatcaggcag aattagatga actgctttca gaacttgatt tttaacctca
    11401 acttaatgtt taaccctcct gcttgataac aactatgcca tcacctaatc ttcccagtga
    11461 aattgaaaat cgtaaaagtg aacatctgcg agtttgtatc gaaaaagatg tagaatttca
    11521 acaacttaca agcggtttag aaaaatatcg ttttacccat tgttgtcttc ctgaacttga
    11581 ccgtagcgat attgaactgg ggacaacctt tttagggaaa tctttaaaag ctccaattct
    11641 catctcttcc atgaccggag gaacagaatt agcccattta gtcaatactc gattggcaac
    11701 ggtcgctcaa cgctatggtt tagcgatggg ggtgggttct caacgcattg cactcgaaca
    11761 accggaatta gcgccgacct ttgcagtccg ttctctggcg ccggatattc tcctgttagc
    11821 gaatttaggg gctgtacagt taaattacgg ctgcggttta gaagactgtt taaaattggt
    11881 ggaattatta gaagctgatg ccttaattct gcatctcaat cctttacaag aatgggtgca
    11941 atcgggaggc gattctaatt ttaaagggtt actcgctaaa attcagcaaa tttgcgctca
    12001 attacccgtt cctgtcatcg ccaaagaagt cggaaatggc atctctgcgg tgatggccaa
    12061 acaattaatt gaagccggag tcgccgcgat tgatgtggcg ggagccggag gcacgtcctg
    12121 ggccaaagtc gaaagccaaa gagccaaaga caacagacaa aggcatctcg gacaagtttt
    12181 tgccgattgg ggtttaccta cggctgaatg tattaccgcc attcggtcga tgaattcaac
    12241 cattccttta attgcttctg ggggcttaaa aaatggctta gatcttgcca aatctatcgc
    12301 tctaggagcc gatttaggag ggttggctcg tccgtttctc gtagcagcga ttgaatcaga
    12361 agccgccgtt gatgagttgg taaaattttt aattgctgaa cttgaaattg ttttattttg
    12421 taccggaaat cctaatttat ccacccttaa aacttcagga gccttaaaac catgttaaag
    12481 ttttcaatgg aattgtgtta tcctcagctt gatatcaaaa ctttaagcgt tggcactttg
    12541 ggtcctaaag aaaccagcag cgaacaaacc ttaaattatc taatttctca atggaaatta
    12601 caacagattt cggttaatag tcatttattt gatagcttta cagatttaaa ggaatcttta
    12661 ctccaaaatc agatagattt ggcgttagtc ccccatgcct atgaaaaaat taatgatttc
    12721 tatatggaac cgaggtttaa actaggtttt atcttcacct atcccacacc cgtttacgga
    12781 ttagccaagc gaaaaaatga agaaatcgtt ttagaaaatt gtaccctggt cactcatccc
    12841 gctcctcttc ctttacttcc ttatttatta cctggcgacc tgaatcaaaa taagattaaa
    12901 atcaaatttg tcaattctac cagtgtggcc gctattcaag ttaaacaagg gttggcagat
    12961 ttagccatta ccaatgaaaa tgccctccga gaatatgatt tagaatttat ttcacaatat
    13021 ggtaaaattg agatgagttg gtctttattt cacaaaaagg aaaacaccat gattcaaagt
    13081 atttatttac cagtgcatac ctaaaaaagc tacctatccg ctcaaaatag ttgccttcat
    13141 cacataaaaa taattgagag tttaaatctc aatttcattt tgaacctgta ccctaaaatc
    13201 atgtctgaat ttttcccaat tcccaagcct attaaactca atcctcatgt agaattagag
    13261 gtttttcaat gccaagatac catttttcaa ttatacgtta tagctcctaa tgctaaactt
    13321 gaatcccacc aacatcctga aagtcaaatt ggcatggtat tctcagcaga actagaactg
    13381 tatattaaag atttgattaa acccttaaga cctttgcaag atgtttatat agctgatggc
    13441 aatattcctc atggtgcttt taatccttta tcagaaccga tgattggatt tgatcttaaa
    13501 cggattacct ctgctttacc gtcagaagat gttttattaa cactatccaa caaccaagat
    13561 aaaatcactc atttaccttg tcaatctgtt aagggttctt ggtttgaaat tgtcatgatg
    13621 aaaatccctt ctggttattc cattccccca catcaaggtg agcaagaaga aatcggattt
    13681 attttgaatg gaaaattaga aatctccata gaaaatgaag gacagttttt agaatatggt
    13741 caaatttatt atgctccttc aaaagtttta aaaaagggat ataattcatc gaaacaagat
    13801 attaatttga ttaaaatttt aatttagttc gttttatgat tttaagttta acctcaaaat
    13861 gctaggacaa agtttatgga tttaggatta aaagataaag tggctttgat tacgggaagt
    13921 agtgcgggaa ttgggtttac tattgctgaa aaattagcag aagaaggctg tcacttaatt
    13981 atttgtggtc gcaattccca acgcttagaa caagcttatc aatctctggc tcaagcttat
    14041 cctgtccaag aaattctgag tttagtggct gatgtccatc aagctcaaga ttctgaacaa
    14101 ttaatacagg actctttaaa tcaatatggc aaaattgaca ttttagtcaa taattctgaa
    14161 ggagctaact ttgctgataa tttaattgaa aacctttccg atgaagattg gttaaacgtt
    14221 tttcaaggaa aattaatggg ttatattcgc ttaaccaatt tagtgttacc gattatgaaa
    14281 aaacaacatt ggggaagaat tgttaatatc attgggacat cgggaaaaga gccatctcct
    14341 cgtttagtta aatcgggtgt tgtcaatgca gctttaatga attttaccaa atcagtagct
    14401 agacaaaccg ccccctataa tgttttaatt aatagtgtta accccggcgt tattgacacc
    14461 cctagacatc gagaatattt agaaatttat gccaaaaagg agggaacgac cccagattta
    14521 atccgagaaa gaattctaaa aacaattccc atgaatcgaa ttggtacgac tgaagaattt
    14581 gctaatctcg ttgtattttt agcttcagaa tgtgcgagtt atataacggg aattacgatt
    14641 ccgatagatg ggggtttatc ctcgtcagca ttttaaattg atctgtcaag ccaaaatcaa
    14701 caaccacaag tgttatgaat agcgaatcta aatctcaaat gttagacaaa tttgttccct
    14761 attatccgac taaagatact cgtaactttc ccattttttc ctatcttatc aataatgtta
    14821 atatttggag gctgaaacac aaatttaaac aagagcttga acaaccttcg gtgatcctgg
    14881 tttatcaaat gggtaaagtt ggttctgcta atctttatct ggctattaaa agaacctttc
    14941 cagaaaaagc ggtgtatcat gttcataatt taaacccaga aattgttgcc aaaatttggg
    15001 ataaaattca tcttactcaa ccttattatt tgagtacgat agaacattct ttgaccacca
    15061 aatatttaag tgatcatctc gaaacaatta aggataagga taagatcaga attattgcgg
    15121 gagtaagaga tcccatcgct cgtaatattt cttggttttt ccaaattatc gattgtgagt
    15181 ctgcttttcc ccaatttttc cgaaaattta aggaaggatt aattacaatt gacgatatgg
    15241 taaattgttt ttggtcacaa aaatttgttt ttagcaaaca gtttgattgg tttgaattag
    15301 agttaaaatc tgtttttgga attgatatca gtgagattga ttttcccaaa gaaaaaggtt
    15361 atacaattgt tgaatttcct gacaaaaaaa ttgagttatt attattcaaa ttagaaaaac
    15421 ttgactcttg tttacaagaa atgacacaag ctttctttgg aattgagaaa ttagattacc
    15481 aaaaattgaa attgattaac gtagatttgg agtatcatcg tatctatgaa aattttaaaa
    15541 atagtctcac ctttagtgat gaatatttag aaaaaattta tgatcaacca ttagtgagtc
    15601 atttttacac cgatgaagaa attaacaaat ttaaactcaa gtggtctagt caacgttaaa
    15661 ggtaattcgt tctaagttta tcgtatttat tgaataaaat ttgattcaat aaactcacgc
    15721 acatttttat ttaatctatt gggaagaata atggtaacac ctcaacaatc tagggttagt
    15781 aaaaaagata ttgaatccat ttatcccctt tctcccatgc agcaggggat gctgtttcat
    15841 tctttatata atccagaatc aaagacgtat ttatcacaaa ttcaaatcac cttgcaaggc
    15901 aatttagata ttaatgcgtt ccaacaagct tggcaaaaag tagtagatag acatagtatt
    15961 ttacggactt gttttgcttg gaaaaaaacc aaacagcctt tacaagtggt tagaaaaaat
    16021 gtcaccttgc cttggtttaa tcaagattgg cgatcacatt ctcccgccga acaagaaact
    16081 aaatttcagg aattattaac ctctgataaa gagcaatatt ttgaattaga taaagtcccc
    16141 ttacttcgat gtcatttaat tcaagtcgaa gatcaaaaat atgaatttat ccatactgga
    16201 catcatattt tattagatgg ttgggcaaca gcaattctgt tgaaagaagt tttcgatttt
    16261 tacgctggac tcatcaacta tcaacccgtc aatttaccca caccccgccc ttatcaagac
    16321 tatattaatt ggctacaaca gcaagatcaa actgaagccg aacgattttg gcgacaaaat
    16381 cttcaaggtt ttacctctcc aactccatta gtcgttgata aaccgttaaa tcctcttgtt
    16441 actcaaagta aaaattatct tcatcaaaaa tcaaaacttt ctccagaaat taccagtcgt
    16501 ctgaaattac tcgcccaaga atatcgcctt actctttcta ccctaattca aggagcttgg
    16561 gctttattat tgcatcatta tagtagtgaa tctgatattg tatttggggc aaccgtttcg
    16621 ggacgaccgc ccaattttac tgggattgaa tcgatggtgg ggatgttttt aaatacctta
    16681 cccgttcgca tccaaattga gtctcaactt gaattattaa cttggtttca acaactacaa
    16741 caagagcatt tagaacgaga gcaatatagt tatagttctc taattgatat tcaaaaatgg
    16801 agtgaaattc cgtcccctca ttcagttttt gaaagttttg ttgtctttga aaatttaccc
    16861 tttagcgaca atgatagtga taatttaggc ggtttacaag tcggtgaaat gcaagattat
    16921 ggcaatgctg attatccctt aacggttatt gtcacccctg gagaagcctt aagtatcaaa
    16981 attatttatc ctcaagaacg atttgaaaat gacaccattg aacggatatt aggtcatttt
    17041 aaaaccttat tagaaggaat cgctattaat ccccatcgtc ggattcaaga cttaccttta
    17101 ttaacggaag ctgaacgtca attattatta attgaatgga atcaaactgc accccaaaag
    17161 cctcttaaac actgcgttca tgaattattt gaacaacaaa ccctcaaaac cccttcagcc
    17221 atcgccgttg tttttcaaga gcaacaatta acctacgaag aactgaatga atctgctaat
    17281 caattggctc attatttaca aaaaattggg gtgagttttc aatctttagt cgggatttgt
    17341 ttagaacggt ctgttaatat ggtaattgcc gttttagcgg tgttaaaagt aggctgtgtt
    17401 tgtgttcccc tagatccaac ctatcctcaa gaaagacttt cttacatcct gcaagacacc
    17461 caaatcaaaa ccttattaac ccaaaaagat tgtcaatccc tcttaaacag tgaaaccatt
    17521 tctcaacgga ttttattgga tgaacaaggg tcagaaattg ccttagaacc caagactaat
    17581 cttgacaacc ccgtgagttt aaaggatttg gcctatatta tttatagttc aggctctacg
    17641 ggtgtgccaa aagggattat gatcctgcat caatccttaa ccaatattat tgagcatcat
    17701 caggcgaaaa tgtcaccgga gagaaatttc ttacaatttg ctcccttcaa tttcgatgtt
    17761 agctatcacg aaatgtttgc agcctggtgt ttaggaggaa ccttatttat tgttccagaa
    17821 gatgcccgct tagaccttgc taaaataagt caattattgg caaataaccc cattcataaa
    17881 gcgattttgc ccgttacttt gttacaacaa ttaattgaaa cctatagtga ggaaacctac
    17941 ttatttgcta acttgcgtga aattatttca gctggagagc aattacaaat tactccaacg
    18001 atgatttctg tattcaaaaa actcgaacat tgtacccttt acaattatta tggacccaca
    18061 gaagcggata tcgttaccag ttataccttt gaccctaatc ctgagctttg gccgaagtat
    18121 attcccattg gtaaacctgc aattaatgtg caagtttata ttttaaattc ccatcttcaa
    18181 cccgtaccta tcggagtgac tggggagcta tatgttgcgg gtggcggttt agcgcggggt
    18241 tatttcaaca atccccaatt aacccaagaa aaatttattg ctaatccctt tagcgataat
    18301 tcattgttgt ataaaactgg agatttagct cgttatttac ccaatggaga cattgaatat
    18361 ttaggaagaa ttgatgatgt ggtgaaagtt agaggttata gaattgaatt aggggaagta
    18421 gaaactattt taaatcaaca tcctcaaatt gcccaagcca ttgctacagt tcagggaaaa
    18481 accgccagag aaaaatattt agccgcttat tttattcccc gtccaggtga aaccgtaaac
    18541 caagttgaat tacgtcattt ccttgaaaac tggctacccg attatatgat tccctctgct
    18601 tttgtggtga tggaatcttt tcaactcagt cctaacggta aagttgatcg aaaagtctta
    18661 ccaatacccg ataaaaaccc cttatcgtta actcaaaatt atgtcgctcc tcgaactgca
    18721 attgaagaag ttttagcagg aatttgggca gaaattttag aagtcgaacg agttgggatt
    18781 gaagacgatt tctttctgtt aggtgggcat tctttaaaag cgattcaact gattagtaaa
    18841 atccgtcaaa ccttagaaat tgaaatttct gtgcgtcaac tttttaatca ctcaaccatc
    18901 ggccaattaa ctcaagtcat gattgaatta gtggggaatg aagggttact aaatgaaatt
    18961 gccgtaacgg ttcaagaaat ttcccaactt tcaccagaag aagttcaagc tttattatct
    19021 caaaactaaa aaaaataagt caaccacttc tgaattatta attacaaatg aaaaacaact
    19081 ctcaagatca acaaaaatta ctcaagctcc tgcttcaaaa aaaaggtatt agttttaaaa
    19141 aagtaaatac tatacctaaa cgccaatcat ccaactctga attaattcct atctctttaa
    19201 ctcagttaga actttggttt tttgctcaat tttatccaga aaattgtatt tataacttgc
    19261 cttgtattta tcgcattgaa ggcttgctta atgttcctgc actagaggaa agcttaagag
    19321 aaattgtcaa acgtcatgaa agtttgcgga caacttttac ttgtatagat ggaaaagtgt
    19381 tccaaaaaat tacagatgat ccagtttttg atttttcaat tcttgaccta caaagactta
    19441 gtgaagtgga gcaaaaaaaa gaaacccaaa gattgttatc agcagaaatt aaccgatctt
    19501 ttgatttaga aaaagattca ttattttgca gtaaaattat aaaatttgct gaaaataact
    19561 atctgttaat tatgacaatc catcatatta ttgctgatgg ttggtctttg aatattttga
    19621 ctaaagagtt aggcattctt tatgaagctt tttgtctgaa taaaccttca cctttgcctg
    19681 aattaccgat tcaatatggt gacttttctc tgtggcaatg gcaatcaata aaagataatt
    19741 catggcaatc tcagctgaat ttttggaaga aacatatagg gattaaccca cccattttaa
    19801 aacttcctac tgattaccca cgcacaacgg ctcaacctgt tgaagcagct attcatcatt
    19861 tcctcatttc ccaaaactta acagacgcat taaagtcatt aagtcatcaa gaaaaagcga
    19921 ctttgtatat gactttatta gccgccttaa aaatattact cttttactat acagaacaga
    19981 cagaaattat tattggtgga gttgcggcta atcgtaacca acccgaaaca caagatttaa
    20041 tcggacttat ggttcagttt ctccccttat atactcatgt agaaggtcaa gccaattttc
    20101 gagacttgct gcatcaagta aaagagatga gtttagagtt tgatgcttat caagaaattc
    20161 cttttatcac gttagtggaa aaattaaaac ccattaggga tactcaatat gctttgtttc
    20221 atcaagtcat tttccttttc cagaatgctc ctaaacaaga tttaaaattc atcaatctga
    20281 cagtcacaga cgagttatta aaaatggata tagaacccca tagtgccgaa aatgatttaa
    20341 ctatatccct tgaagaaact gagcaaggta tgaaaggtgc tttcgtgtat aaagctgatt
    20401 tatttacggc tgaaactatt actcaaatgg aacaatattt tcagcagtta ttgaagaata
    20461 ttgtcactga tcctaataaa accatttctg atctatgtcc tttctctgaa tccgtctctt
    20521 tctcagacaa tacttccccc ttgtctttat caatcaatga aattaaatct aatgacttac
    20581 cccataatct aactagagaa accatggtca atatctggca agaagtttta gaattagaag
    20641 aaattagtgt taatgataac ttttttgacc ttggggggga ttctcaaaaa gttattcagg
    20701 taattgataa aattggtaaa attcttaaaa ttaattgtac tttgcgtgat ttttttgaaa
    20761 atcccactgt agcacgtcta atcacaacct ttaaaaataa atgaatttaa gcgtatttcc
    20821 ctagctttaa aaatggtata attacaaaaa aaatacagaa aaaaatgaca aatcatctct
    20881 ttgatttaac aggtaaagtt gcaattatca cgggtgctgc ccgaggaatt ggtcgggtac
    20941 tagcgcaagg attagcacaa gctggagcta aggtagtaat tggtgatatt aatcaagttg
    21001 gtgctgaaca aacggttcaa ctgattcaag aagcaggagg cgaggccatc gcaatccaga
    21061 ccgatgttcg tcaacgtcaa gcttgtcaga atttaattaa ccagacggtt gctaattatg
    21121 gtcaactcga tattatggtc tgtaatgcag gggttgaaat tctcaaaaac actgatgaat
    21181 tagaggaatt tgaatgggat caggttatta atgttgactt aaaaggttat tttaattgcg
    21241 ctcaactcgc aaccaaacaa atgatcaaac aaggaacaaa gggatcaatt attatgaatt
    21301 cttctatctg tgctttcgtt gctgttccca aatcttcagg agcatatagc gccgcaaaag
    21361 gtggtgtcaa tcaattagta aaatccctag cggtcgaatt agctagtcac aaaattcgag
    21421 tcaatgcttt tgcaccgggg tatatgaata atatgatgga aggaacagaa ggtttacgtt
    21481 caacttccga tgaaatggac gaattatata ctagaattcc catgaaacga accggagatt
    21541 tagaagagtt aattggccct gtcgtgtttt tagcgtccga agcttcctct tatgtaactg
    21601 gagcaatttt aatggtagat ggaggttata ccgctattta gcatcaataa ttaaacaatt
    21661 tttaggttga tttgtatcca tcaaaccaac ctaaaatcac tgaattaatc ctatttaaac
    21721 catgtcaaaa atgaaccata actctcaaga caaacagaaa ttactcaagc tgttactaca
    21781 aaaaaaagga atcggtgtaa aaacaaatac gatacctact aggaatccgt ctcaacttgt
    21841 accgctttct ttttctcaag aacgactttg gtttttgtac caattagaag ctaacggcta
    21901 tacctataat atgccgtttc gctttcaaat tgacggcaat ttggacgtta atatctttag
    21961 aaaagctttg gaaactatta tgcaacgtca tgaattgttg cgaacttgtt ttcaagaagt
    22021 tgacaaaact cctcgacaaa ttattaaact aaaaattcag ttaaatttgc ctttattgga
    22081 tttactacaa gaactttctc atttatatga agcttttgac aaaaataatc taatccttga
    22141 tcaaatttcc ctattcaata cggtgatttt cccgtttggc aaagacaaca gttattttgc
    22201 atattttact aaaagtgggt ttttaacaca ataaatgtcg atttaatcat acccgataag
    22261 ctgaattgca ccagcttatc tcatccattc attaatttca cgagtaaaat cttatgttta
    22321 atttaaaaca tcaattatat ttattaattt caaaattttt agaaaaacaa aaacggatcg
    22381 aaaaacataa aaaactttcc gacaatgcta catttcacag ttccgtcaaa tttatcggaa
    22441 agtgtataaa ctatagggag gataaaactc taattcaaat tggagagaat acagtaatta
    22501 tcggagaatt agctatattt ccttttggtg gaaaaataga aatagggaga aattgttata
    22561 ttggtgaagg aactcgaatt agatcagcta cttctatcaa aattggaaac gaagttataa
    22621 tttccgatga tgtcagtatt tatgataccg atgctcattc attaaattat gttttaagac
    22681 agaaagaatt tatggaagta ctcattttga ataatctgat taaggatgct aaggatgttg
    22741 atatacaatc tgcacccgtg gtgatagaag atcatgtttg gattggattt aatgttgcga
    22801 ttcttaaagg ggttacgatt gggaaagggg caattattgg agcaggttct gttgtaacaa
    22861 aagatgtaga accttttacc atcgttgcgg gtaatcctgc caaaattatc aaacgattat
    22921 gaatctgatc caattcggtt aatattcatt cctgatctgt agaaaagcca gaaaatagta
    22981 gtaatataat ttgtgataat aatgcagatt tttatggtat gctgaattga tgtctaactc
    23041 aagagataga cattaaaagt tctaatgtcc cccattttag atcaaggaga atcctatgaa
    23101 tgttgcagaa aaaacctcag atagtataaa tctcaaagaa gatgtccgaa ctttcaatca
    23161 atctcttcaa gaatttttaa gatttattca agtttattgg tatcctaaag aacaccagga
    23221 tagagccttt tcacagatta ttcgttcctg gggaatgctc gttttattgt ttttattatt
    23281 agtgggatta gtaggtctta atgcgtttaa tagttttgtt tttagagact taattacctt
    23341 cacagaagct agggatgcag aaaaattaac tcatcttgtc attatttatg cgattaccct
    23401 aggcagtatg acgtttttcg gaggattgtc caagtttctt aaaaaactaa ttgcgctaga
    23461 ttggtatcaa tggatcaata gtagtatctt gcaaaaatat tttaaaaatc gtgcttatta
    23521 tcaaatcaat tttaaaggag atattgaaaa tccagatcaa cgtttatccc aagaaattca
    23581 acccattgcc agaacaacga tggacttttt aacaacctgt gttgaaaaag ttatggagat
    23641 gctggttttt attgccattc tttggtcaat ttctaaaacc atttctattg tgcttctggt
    23701 ttatacgatt attggaaata ttgttgccac ctatattact caacaattaa ataaagtcaa
    23761 taaacaacaa ttagaaatcg aaggaaccta taaatacgcc atgactcatg ttcggacaca
    23821 cgccgaatca attgcatttt ttagagggga agaaaaagag ttaaatatta ttcaaagaaa
    23881 gttcaatcag gtgattaaaa tcatgattga aagaattaat tgggaaagaa cccaagaatt
    23941 ttttaaccgc ggctatcaat ccattgttca aatcttcccc ttcttaattg tttccccatt
    24001 atatattagt ggtgaaattg agtttggaca agttaaccaa gtcagctatt gttgctattt
    24061 cttttccaca gccttatccg tgttagtgga tgaatttgga cgctcccggg agtttattaa
    24121 ttatattgaa cgtttagaag agttttacca agctttagag ggtgtaagcg aacaaaccaa
    24181 cccagttaat accattaaag tcattgaaga taacaatcta gcttttgatg atgtcacctt
    24241 acaaactccc gatgccgcta aagtgattgt cgaacattta tccctgtccg ttgaaccagg
    24301 ggaaggttta ttaattgttg ggccaagtgg tcgaggaaaa agttctcttt tacgcgctat
    24361 ttctgggtta tggaatacag gtacaggtca tttggtgcga cctcccctcg acgatttatt
    24421 atttttaccc caacgtcctt acatcatttt gggaaacctg cgcgaacagc taatttatcc
    24481 tcaaacgaca acggagatga gtgaatccca attaaaagaa atcttacaag aagttaacct
    24541 acaagatgtt cttaatcgca tcaaaaattt tgatgaggaa gtggattggg aaaatatttt
    24601 atctttagga gaacaacagc gtctagcctt tgcgcgacta ttcgttaatc agccagattt
    24661 tgtgatttta gatgaagcca ccagtgcttt agatttaaaa aatgaagatc atttatataa
    24721 acagttacaa caaactggca agacctttat tagtgtcgga catcgagaaa gtttgtttaa
    24781 ctatcatcaa agggttttgg aactttccga ggattctact tggcgtttaa tgagaatggc
    24841 agactatcat ccatcaacag cgattgcaac tcattctaac aatgagcaaa ccgttgatga
    24901 aacgatagaa attgtctctg aaataaacaa tcaagacaat tttacccatc aagaaatgca
    24961 aaaactgacc aattatagct taagtaccat caaaaacaaa gcccgtcgag gtcaaacgat
    25021 tgttgccaat gatggcatga gctatcgtta tgacaaaacc cttgatattg ccaaatgggt
    25081 gagagtttag cttctcaggg agcttcgatt gaacttaaaa aggtatcttg ccgcagttcg
    25141 ggaaccttta aagaagattc tcgaccgatt acattgtgaa gtaggtaggc gttaaaagtt
    25201 gtcagacacc ctccttatca aaggggggat taagggggga tcggcacccc ccttatcaag
    25261 gggggcaggg gggatcgaac ctaaaatcca tttttaattt aattataacc agctacttag
    25321 ccaattcaag tctgaattgg tagattaaaa tccgcctgga cttaaataac tgggattttc
    25381 ctgtagggaa gtatcgaagg g
//
