BGC0000301 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000301 (Planktothrix agardhii NIVA-CYA 126/8)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	23,949	anabaenopeptin	NRPS:Type I	85%

BGC0000301 - Region 1 - NRPS

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Location: 1 - 23,949 nt. (total: 23,949 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 23,950
Label		BGC0000301

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000301	1.00	NRP	anabaenopeptin 908, anabaenopeptin 915	Planktothrix agardhii NIVA-CYA 126/8
BGC0001479	0.46	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001133	0.42	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0001132	0.36	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0002437	0.35	NRP	thermoactinoamide A	Thermoactinomyces sp. AS95
BGC0000426	0.35	NRP	sevadicin	Paenibacillus larvae
BGC0000342	0.33	NRP	enniatin	Fusarium equiseti
BGC0001128	0.33	NRP	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000302	0.33	NRP	anabaenopeptin	Anabaena sp. 90
BGC0000901	0.33	Other	ferrichrome	Aspergillus niger

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000301	1.00	NRP	anabaenopeptin 908, anabaenopeptin 915	Planktothrix agardhii NIVA-CYA 126/8
BGC0001479	0.76	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001133	0.73	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0001132	0.69	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0002437	0.68	NRP	thermoactinoamide A	Thermoactinomyces sp. AS95
BGC0000426	0.68	NRP	sevadicin	Paenibacillus larvae
BGC0000342	0.67	NRP	enniatin	Fusarium equiseti
BGC0001128	0.66	NRP	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000302	0.66	NRP	anabaenopeptin	Anabaena sp. 90
BGC0000901	0.66	Other	ferrichrome	Aspergillus niger

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 23949:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Arg - D-Lys) + (Val) + (X - NMe-X) + (Ile)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

apnA

Search NORINE for peptide: strict or relaxed

AMP-binding (9..417): Arg

nrpys: Arg

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVESIGAIAK
Nearest Stachelhaus code(s):: Arg DVESIGAIAK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1098..1502): Lys

nrpys: Lys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAEDIGSVVK
Nearest Stachelhaus code(s):: Lys DAEDIGSVVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

apnB

Search NORINE for peptide: strict or relaxed

AMP-binding (470..869): Val

nrpys: Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: val (Val)

Stachelhaus prediction details:

Stachelhaus sequence:: DALWIGGVFK
Nearest Stachelhaus code(s):: Val DALWIGGVFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

apnC

AMP-binding (512..906): X

nrpys: Hty

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DLGFTGCVTK
Nearest Stachelhaus code(s):: Hty DLGFTGCVTK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1566..1960): X

nrpys: Hty

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DLGFTGCVTK
Nearest Stachelhaus code(s):: Hty DLGFTGCVTK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

apnD

Search NORINE for peptide: strict or relaxed

AMP-binding (542..944): Ile

nrpys: Ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: ile (Ile)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGVTFK
Nearest Stachelhaus code(s):: Ile DAFFLGVTFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)