BGC0000301: anabaenopeptin 908 biosynthetic gene cluster from Planktothrix agardhii NIVA-CYA 126/8
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Location: 1 - 23,949 nt. (total: 23,949 nt).
This entry is originally from NCBI GenBank EF672686.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000301
Short description anabaenopeptin 908 biosynthetic gene cluster from Planktothrix agardhii NIVA-CYA 126/8
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
EF672686.1
via
Compounds
  • anabaenopeptin 908
  • anabaenopeptin 915
Species Planktothrix agardhii NIVA-CYA 126/8 [taxonomy]
References
Chemical products information
anabaenopeptin 908 Evidence:
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C45H68N10O10
anabaenopeptin 915 Evidence:
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C48H65N7O11
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABV79985.1
  • apnA
 1 - 6501 (+) ApnA
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    • ABV79986.1
    • apnB
    		 6507 - 9743 (+) ApnB
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      • ABV79987.1
      • apnC
      		 9882 - 17606 (+) ApnC
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        • ABV79988.1
        • apnD
        		 17603 - 21865 (+) ApnD
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          • ABV79989.1
          • apnE
          		 21913 - 23949 (+) ApnE
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            Biosynthesis information

            Biosynthetic modules

            Name
            Unk01
            Type
            nrps-type1
            Genes
            apnA
            Substrates
            arginine, tyrosine (evidence: ATP-PPi exchange assay, Sequence-based prediction)
            Integrated Monomers
            Domains
            adenylation
            Name
            Unk02
            Type
            nrps-type1
            Genes
            apnA
            Substrates
            lysine (evidence: Sequence-based prediction, Homology)
            Integrated Monomers
            Domains
            adenylation
            Name
            Unk03
            Type
            nrps-type1
            Genes
            apnB
            Substrates
            valine, isoleucine (evidence: Sequence-based prediction, Homology)
            Integrated Monomers
            Domains
            adenylation
            Name
            Unk04
            Type
            nrps-type1
            Genes
            apnC
            Substrates
            homotyrosine (evidence: Sequence-based prediction, Homology)
            Integrated Monomers
            Domains
            adenylation
            Name
            Unk05
            Type
            nrps-type1
            Genes
            apnC
            Substrates
            homotyrosine, alanine (evidence: Sequence-based prediction, Homology)
            Integrated Monomers
            Domains
            adenylation
            Name
            Unk06
            Type
            nrps-type1
            Genes
            apnD
            Substrates
            isoleucine, phenylalanine (evidence: Sequence-based prediction, Homology)
            Integrated Monomers
            Domains
            adenylation
            Annotation changelog

            Entry version: 4

            Date
            Changes
            Submitters
            Reviewers
            2022-10-07
            Update chemical activity to schema version 2.11
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 3

            Date
            Changes
            Submitters
            Reviewers
            2022-09-15
            Updated bioactivity data
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            2022-09-15
            Added NRP substrate specificities
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 2

            Date
            Changes
            Submitters
            Reviewers
            2019-10-16
            Migrated from v1.4
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            2019-10-16
            Updated compound(s) information (NPAtlas curation)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 1

            Date
            Changes
            Submitters
            Reviewers
            2015-06-12
            Submitted
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            Detailed domain annotation
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