BGC0000305: arthrofactin A biosynthetic gene cluster from Pseudomonas sp. MIS38
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Location: 1 - 40,430 nt. (total: 40,430 nt).
This entry is originally from NCBI GenBank AB107223.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000305
Short description arthrofactin A biosynthetic gene cluster from Pseudomonas sp. MIS38
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP (Other lipopeptide)
Loci NCBI GenBank: AB107223.1
Compounds
  • arthrofactin A
Species Pseudomonas sp. MIS38 [taxonomy]
References
Chemical products information
arthrofactin A
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C64H111N11O20
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAC67533.1
 359 - 1153 (-) putative DNA binding protein
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  • BAC67534.2
  • arfA
 1642 - 8055 (+) arthrofactin synthetase A
  • Scaffold biosynthesis
Sequence-based prediction
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  • BAC67535.1
  • arfB
 8237 - 21253 (+) arthrofactin synthetase B
  • Scaffold biosynthesis
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  • BAC67536.1
  • arfC
 21319 - 39093 (+) arthrofactin synthetase C
  • Scaffold biosynthesis
Sequence-based prediction
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  • BAC67537.1
 39220 - 40308 (+) putative periplasmic protein
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  • BAC67538.1
 40311 - >40430 (+) putative ABC transporter protein
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NRP-specific information
Subclass Other lipopeptide
Cyclic? yes
Release type
  • Macrolactonization
Lipid moiety 3-OH-decanoic acid
NRP-synthases
Gene Modules
arfA
Module 2
Specificity: aspartic acid
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Module 1
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Starter
arfB
Module 3
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Module 4
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Module 5
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Module 6
Specificity: serine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
arfC
Module 7
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Module 8
Specificity: serine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Module 9
Specificity: isoleucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Module 10
Specificity: isoleucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Module 11
Specificity: aspartic acid
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: KRKW7VUNYGF36O3Z7FAQ6YXG, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected NRP module activity
  • Updated NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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