BGC0000307 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000307 (Aureobasidium pullulans)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	NRPS	1	35,683	High	AbT1	NRPS:Type I

BGC0000307 - Region 1 - NRPS

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Location: 1 - 35,683 nt. (total: 35,683 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)

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core biosynthetic genes

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 35,684
Label		BGC0000307

Tailoring functions

Ligases: ligase

aba1: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000307.4	0.97	NRPS	AbT1	Aureobasidium pullulans
BGC0001833.4	0.69	NRPS	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.4	0.66	NRPS	xenematide	Xenorhabdus nematophila AN6/1
BGC0001844.4	0.63	NRPS	holrhizin A, holrhizin B, holrhizin C, holrhizin D	Paraburkholderia rhizoxinica HKI 454
BGC0000393.5	0.58	NRPS, PKS	myxoprincomide-c506	Myxococcus xanthus DK 1622
BGC0001636.4	0.58	NRPS	KK-1	Curvularia clavata
BGC0002660.2	0.56	NRPS	pentacitidin A, pentacitidin B	Chitinophaga eiseniae
BGC0001133.4	0.53	NRPS	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0001211.5	0.52	NRPS	albachelin	Amycolatopsis alba DSM 44262
BGC0000423.5	0.52	NRPS	scabichelin	Streptomyces scabiei 87.22

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000307.4	0.97	NRPS	AbT1	Aureobasidium pullulans
BGC0001833.4	0.69	NRPS	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.4	0.66	NRPS	xenematide	Xenorhabdus nematophila AN6/1
BGC0001844.4	0.63	NRPS	holrhizin A, holrhizin B, holrhizin C, holrhizin D	Paraburkholderia rhizoxinica HKI 454
BGC0000393.5	0.58	NRPS, PKS	myxoprincomide-c506	Myxococcus xanthus DK 1622
BGC0001636.4	0.58	NRPS	KK-1	Curvularia clavata
BGC0002660.2	0.56	NRPS	pentacitidin A, pentacitidin B	Chitinophaga eiseniae
BGC0001133.4	0.53	NRPS	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0001211.5	0.52	NRPS	albachelin	Amycolatopsis alba DSM 44262
BGC0000423.5	0.52	NRPS	scabichelin	Streptomyces scabiei 87.22

Similar known clusters from MIBiG 4.0

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Detailed domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 35683:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - NMe-Val - Phe - NMe-Phe - Pro - aIle - NMe-Val - Leu - NMe-Val)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

aba1: X - Val - Phe - Phe - Pro - aIle - Val - Leu - Val

Search NORINE for peptide: strict or relaxed

AMP-binding (291..687): X

nrpys: Hmp

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A