BGC0000308: aureusimine A biosynthetic gene cluster from Staphylococcus aureus subsp. aureus str. JKD6008
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Location: 176,051 - 183,901 nt. (total: 7,851 nt).
This entry is originally from NCBI GenBank CP002120.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000308
Short description aureusimine A biosynthetic gene cluster from Staphylococcus aureus subsp. aureus str. JKD6008
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
CP002120.1
176051 - 183901
via
Compounds
  • aureusimine A
  • aureusimine B
  • aureusimine C
Species Staphylococcus aureus subsp. aureus str. JKD6008 [taxonomy]
References
Chemical products information
aureusimine A Evidence:
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C14H16N2O2
Chemical database entries
PubCHEM
aureusimine B Evidence:
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C14H16N2O1
Chemical database entries
PubCHEM
aureusimine C Evidence:
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C11H18N2O1
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SAA6008_00157
  • ADL64235.1
  • ausA
 176051 - 183244 (+) aureusimine non-ribosomal peptide synthetase
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    • SAA6008_00158
    • ADL64236.1
    		 183257 - 183901 (+) 4'-phosphopantetheinyl transferase-like protein
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      Biosynthesis information

      Biosynthetic modules

      Name
      Unk01
      Type
      nrps-type1
      Genes
      ausA
      Substrates
      valine (evidence: )
      Integrated Monomers
      Domains
      adenylation
      Name
      Unk02
      Type
      nrps-type1
      Genes
      ausA
      Substrates
      tyrosine, phenylalanine, 4-aminophenylalanine (evidence: ATP-PPi exchange assay [1])
      Integrated Monomers
      Domains
      adenylation
      Annotation changelog

      Entry version: 4

      Date
      Changes
      Submitters
      Reviewers
      2022-10-07
      Update chemical activity to schema version 2.11
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

      Entry version: 3

      Date
      Changes
      Submitters
      Reviewers
      2022-09-15
      Add compound details
      • (ID: SJG3CBEHSM6A3I74YXLH6GLA)
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      2022-09-15
      Updated bioactivity data
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      2022-09-15
      Added NRP substrate specificities
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

      Entry version: 2

      Date
      Changes
      Submitters
      Reviewers
      2019-10-16
      Migrated from v1.4
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

      Entry version: 1

      Date
      Changes
      Submitters
      Reviewers
      2015-06-12
      Submitted
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      Detailed domain annotation
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