BGC0000310: bacitracin biosynthetic gene cluster from Bacillus licheniformis
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Location: 1 - 48,774 nt. (total: 48,774 nt).
This entry is originally from NCBI GenBank AF007865.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000310
Short description bacitracin biosynthetic gene cluster from Bacillus licheniformis
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: AF007865.2
Compounds
  • bacitracin
Species Bacillus licheniformis [taxonomy]
References
Chemical products information
bacitracin
Copy SMILES
C66H103N17O16S1
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAD21211.1
  • bacT
 411 - 1115 (+) BacT
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  • AAC06346.1
  • bacA
 1451 - 17218 (+) bacitracin synthetase 1
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  • AAC06347.1
  • bacB
 17330 - 25153 (+) bacitracin synthetase 2
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  • AAC06348.1
  • bacC
 25258 - 44337 (+) bacitracin synthetase 3
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  • AAD21216.2
  • bacR
 44497 - 45213 (+) BacR
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  • AAD21212.2
  • bacS
 45191 - 46237 (+) BacS
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  • AAD21213.1
  • bcrA
 46313 - 47233 (+) BcrA
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  • AAD21214.1
  • bcrB
 47334 - 47960 (+) BcrB
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  • AAD21215.1
  • bcrC
 48081 - 48692 (+) BcrC
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
bacA
Module ?
Specificity: isoleucine
Evidence for specificity:
Module ?
Specificity: cysteine
Evidence for specificity:
Module ?
Specificity: leucine
Evidence for specificity:
Module ?
Specificity: glutamic acid
Evidence for specificity:
Module ?
Specificity: isoleucine
Evidence for specificity:
bacB
Module ?
Specificity: lysine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: ornithine
Evidence for specificity:
bacC
Module ?
Specificity: isoleucine
Evidence for specificity:
Module ?
Specificity: phenylalanine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: histidine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: aspartic acid
Evidence for specificity:
Module ?
Specificity: asparagine
Evidence for specificity:
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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