BGC0000312 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000312 (Beauveria bassiana)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	41,205	bassianolide	NRPS:Type I	100%

BGC0000312 - Region 1 - NRPS

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Location: 1 - 41,205 nt. (total: 41,205 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 41,206
Label		BGC0000312

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000312	1.00	NRP	bassianolide	Beauveria bassiana
BGC0000313	0.44	NRP	beauvericin	Beauveria bassiana
BGC0000342	0.42	NRP	enniatin	Fusarium equiseti
BGC0000307	0.28	NRP	AbT1	Aureobasidium pullulans
BGC0002157	0.25	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0002437	0.24	NRP	thermoactinoamide A	Thermoactinomyces sp. AS95
BGC0002135	0.24	NRP	bovienimide A	Xenorhabdus bovienii SS-2004
BGC0001261	0.24	NRP	AM-toxin	Alternaria alternata
BGC0001132	0.24	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0002518	0.24	NRP	syringafactin A, syringafactin C	Pseudomonas sp. SZ57

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000312	1.00	NRP	bassianolide	Beauveria bassiana
BGC0000313	0.74	NRP	beauvericin	Beauveria bassiana
BGC0000342	0.73	NRP	enniatin	Fusarium equiseti
BGC0000307	0.61	NRP	AbT1	Aureobasidium pullulans
BGC0002157	0.59	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0002437	0.58	NRP	thermoactinoamide A	Thermoactinomyces sp. AS95
BGC0002135	0.57	NRP	bovienimide A	Xenorhabdus bovienii SS-2004
BGC0001261	0.57	NRP	AM-toxin	Alternaria alternata
BGC0001132	0.57	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0002518	0.57	NRP	syringafactin A, syringafactin C	Pseudomonas sp. SZ57

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 1244 - 41205:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-Hiv - NMe-Leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

Bsls

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AMP-binding (491..887): D-Hiv

nrpys: D-Hiv

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GALMVVGSIK
Nearest Stachelhaus code(s):: D-Hiv GALMVVGSIK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1566..1973): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DGYIIGGVFK
Nearest Stachelhaus code(s):: Leu DGYIIGGVFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)