BGC0000313: beauvericin biosynthetic gene cluster from Beauveria bassiana
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Location: 1 - 33,475 nt. (total: 33,475 nt).
This entry is originally from NCBI GenBank EU886196.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000313
Short description beauvericin biosynthetic gene cluster from Beauveria bassiana
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
EU886196.1
via
Compounds
  • beauvericin
Species Beauveria bassiana [taxonomy]
References
Chemical products information
beauvericin Evidence:
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C45H57N3O9
Chemical database entries
PubCHEM
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACI30651.1
 1 - 2705 (-) hypothetical protein
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    • ACI30652.1
    		 3519 - 5598 (-) cyclophilin-type peptidyl-prolyl cis-trans isomerase
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      • ACI30653.1
      		 6216 - 6956 (+) hypothetical protein
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        • glycolate_oxidase_L-lactate_2-monooxygenase
        		 7041 - 7751 (-)
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          • ACI30654.1
          • kivr
          		 7882 - 9270 (-) ketoisovalerate reductase
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            • ACI30655.1
            • Beas
            		 11511 - 21080 (+) BEAS beauvericin nonribosomal cyclodepsipeptide synthetase
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              • ACI30656.1
              		 23275 - 24112 (+) hypothetical protein
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                • ACI30657.1
                		 25822 - 27691 (+) calreticulin
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                  • ACI30658.1
                  		 28615 - 30425 (+) methylmalonate semialdehyde dehydrogenase
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                    • ACI30659.1
                    		 31637 - 33475 (+) hypothetical protein
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                      Biosynthesis information

                      Biosynthetic modules

                      Name
                      Unk01
                      Type
                      nrps-type1
                      Genes
                      Beas
                      Substrates
                      2R-hydroxyisovaleric acid (evidence: Structure-based inference)
                      Integrated Monomers
                      Domains
                      adenylation
                      Name
                      Unk02
                      Type
                      nrps-type1
                      Genes
                      Beas
                      Substrates
                      phenylalanine (evidence: Structure-based inference)
                      Integrated Monomers
                      Domains
                      adenylation
                      Annotation changelog

                      Entry version: next

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2024-07-24
                      MIBiG v4 annotathon
                      • (ID: C62OJVVH7XOTOTFZSJT727YU)
                      • (ID: X3QVFXOIMTNXSB4JQGP4RI6A)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                      Entry version: 3

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2022-09-15
                      Added NRP substrate specificities
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                      Entry version: 2

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2019-10-16
                      Migrated from v1.4
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      2019-10-16
                      Updated compound(s) information (NPAtlas curation)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                      Entry version: 1

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2015-06-12
                      Submitted
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      Detailed domain annotation
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