BGC0000321 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000321 (Achaetomiella virescens)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	43,979	chaetocin	NRPS:Type I	100%

BGC0000321 - Region 1 - NRPS

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Location: 1 - 43,979 nt. (total: 43,979 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 43,980
Label		BGC0000321

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000321	0.90	NRP	chaetocin	Collariella virescens
BGC0002226	0.25	NRP	acu-dioxomorpholine B, acu-dioxomorpholine A	Aspergillus aculeatus ATCC 16872
BGC0001636	0.23	NRP	KK-1	Curvularia clavata
BGC0001585	0.22	Alkaloid	melinacidin IV	Escovopsis weberi
BGC0000372	0.22	NRP	hexadehydroastechrome, terezine-D, astechrome	Aspergillus fumigatus Af293
BGC0001240	0.21	NRP	serinocyclin A, serinocyclin B	Metarhizium robertsii
BGC0001641	0.20	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000417	0.20	NRP	rhodochelin	Rhodococcus jostii RHA1
BGC0002424	0.19	NRP	saccharochelin A, saccharochelin B, saccharochelin C, saccharochelin D, saccharochelin E, saccharochelin F, saccharochelin G, saccharochelin H	Saccharothrix sp.
BGC0000349	0.19	NRP	erythrochelin	Saccharopolyspora erythraea NRRL 2338

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000321	1.00	NRP	chaetocin	Collariella virescens
BGC0002226	0.58	NRP	acu-dioxomorpholine B, acu-dioxomorpholine A	Aspergillus aculeatus ATCC 16872
BGC0001636	0.56	NRP	KK-1	Curvularia clavata
BGC0001240	0.54	NRP	serinocyclin A, serinocyclin B	Metarhizium robertsii
BGC0001585	0.53	Alkaloid	melinacidin IV	Escovopsis weberi
BGC0001641	0.53	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000417	0.53	NRP	rhodochelin	Rhodococcus jostii RHA1
BGC0001336	0.53	Alkaloid	erdasporine A, erdasporine B, erdasporine C	uncultured bacterium
BGC0001671	0.53	NRP	monobactam	Agrobacterium tumefaciens
BGC0000292	0.52	NRP	acetylaranotin	Aspergillus terreus NIH2624

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 9833 - 43979:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Trp)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg1_orf10

Search NORINE for peptide: strict or relaxed

AMP-binding (1050..1463): Trp

nrpys: Trp

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DYVTYTAICK
Nearest Stachelhaus code(s):: Trp DYVTYTAICK (100% 8Å match)
Stachelhaus code match:: 100% (strong)