BGC0000323: cichofactin A biosynthetic gene cluster from Pseudomonas cichorii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 33,153 nt. (total: 33,153 nt).
This entry is originally from NCBI GenBank KJ513093.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000323
Short description cichofactin A biosynthetic gene cluster from Pseudomonas cichorii
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
KJ513093.1
via Knock-out studies, Gene expression correlated with compound production
Compounds
  • cichofactin A
  • cichofactin B
Species Pseudomonas cichorii [taxonomy]
References
Chemical products information
cichofactin A Evidence:
Copy SMILES
C61H107N13O14
cichofactin B Evidence:
Copy SMILES
C63H111N13O14
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AHZ34234.1
 1 - 795 (-) LuxR
  • Regulation
copy AA seq
copy Nt seq
  • AHZ34232.1
 1142 - 10639 (+) CifA
  • Scaffold biosynthesis
  • Knock-out
copy AA seq
copy Nt seq
  • AHZ34233.1
 10885 - 28374 (+) CifB
  • Scaffold biosynthesis
  • Knock-out
copy AA seq
copy Nt seq
  • AHZ34235.1
 28493 - 29644 (+) MacA
  • Transport
copy AA seq
copy Nt seq
  • AHZ34236.1
 29647 - 31653 (+) MacB
  • Transport
copy AA seq
copy Nt seq
  • AHZ34237.1
 31683 - 32510 (-) LuxR
  • Regulation
copy AA seq
copy Nt seq
Biosynthesis information

Biosynthetic modules

Name
1
Type
nrps-type1
Genes
AHZ34232.1
Substrates
leucine (evidence: Sequence-based prediction)
Integrated Monomers
Domains
condensation (Starter), adenylation, epimerase
Name
2
Type
nrps-type1
Genes
AHZ34232.1
Substrates
leucine (evidence: Sequence-based prediction)
Integrated Monomers
Domains
condensation (Dual), adenylation, epimerase
Name
3
Type
nrps-type1
Genes
AHZ34232.1
Substrates
glutamine (evidence: Sequence-based prediction)
Integrated Monomers
Domains
condensation (Dual), adenylation, epimerase
Name
4
Type
nrps-type1
Genes
AHZ34233.1
Substrates
leucine (evidence: )
Integrated Monomers
Domains
condensation (Dual), adenylation
Name
5
Type
nrps-type1
Genes
AHZ34233.1
Substrates
glutamine (evidence: Sequence-based prediction)
Integrated Monomers
Domains
condensation (DCL), adenylation, epimerase
Name
6
Type
nrps-type1
Genes
AHZ34233.1
Substrates
valine (evidence: )
Integrated Monomers
Domains
condensation (Dual), adenylation
Name
7
Type
nrps-type1
Genes
AHZ34233.1
Substrates
leucine (evidence: Sequence-based prediction)
Integrated Monomers
Domains
condensation (DCL), adenylation, epimerase
Name
8
Type
nrps-type1
Genes
AHZ34233.1
Substrates
leucine (evidence: )
Integrated Monomers
Domains
condensation (Dual), adenylation
Annotation changelog

Entry version: 4

Date
Changes
Submitters
Reviewers
2022-10-07
Update chemical activity to schema version 2.11
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

Entry version: 3

Date
Changes
Submitters
Reviewers
2022-09-15
Corrected NRP module activity
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
2022-09-15
Updated NRP substrate specificities
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

Entry version: 2

Date
Changes
Submitters
Reviewers
2019-10-16
Migrated from v1.4
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

Entry version: 1

Date
Changes
Submitters
Reviewers
2015-06-12
Submitted
  • (ID: 4VPAMSFU7CTQRXZA3KNXYTFK)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 4.0
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.