Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000323.1:
Cluster 1NRP133153

BGC0000323, cichofactin biosynthetic gene cluster from Pseudomonas cichorii. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: cichofactin A
SMILES string: Copy to clipboard
Exact molecular mass: 1109 Da ([M+H]+)
Molecular activity: Antibacterial, Antifungal, Surfactant

Class-specific details

Biosynthetic class(es):
NRP
Nonribosomal peptide subclass:
Other lipopeptide (linear)
3-hydroxydecanoyl acid or 3-hydroxydodecanoyl acid
Thioesterase type:
None
Release / cyclization type:
Unknown

Nonribosomal peptide synthetases:
AHZ34232.1
Module 1
A specificity: Leucine
Evidence for specificity: Sequence-based prediction
AA is epimerized
C domain subtype: Starter
Module 2
A specificity: Leucine
Evidence for specificity: Sequence-based prediction
AA is epimerized
C domain subtype: Dual
Module 3
A specificity: Glutamine
Evidence for specificity: Sequence-based prediction
AA is epimerized
C domain subtype: Dual
AHZ34233.1
Module 4
A specificity: Leucine
Evidence for specificity: Unknown
C domain subtype: Dual
Module 5
A specificity: Glutamine
Evidence for specificity: Sequence-based prediction
AA is epimerized
C domain subtype: DCL
Module 6
A specificity: Valine
Evidence for specificity: Unknown
C domain subtype: Dual
Module 7
A specificity: Leucine
Evidence for specificity: Sequence-based prediction
AA is epimerized
C domain subtype: DCL
Module 8
A specificity: Leucine
Evidence for specificity: Unknown
C domain subtype: Dual

Gene cluster description

cichofactin (BGC0000323). Gene Cluster 1. Biosynthetic class = NRP. GenBank KJ513093. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Knock-out studies, Proven expression in natural host, Sequence-based prediction
MIxS-compliance:Unknown
Contact for this cluster:Monica Hoefte (Ghent University)

Literature references

1. Pauwelyn E et al. (2013) New linear lipopeptides produced by Pseudomonas cichorii SF1-54 are involved in virulence, swarming motility, and biofilm formation. Mol Plant Microbe Interact 26(5):585-98. doi: