BGC0000324: coelibactin biosynthetic gene cluster from Streptomyces coelicolor A3(2)
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Location: 8,504,461 - 8,529,581 nt. (total: 25,121 nt).
This entry is originally from NCBI GenBank AL645882.2.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000324
Short description coelibactin biosynthetic gene cluster from Streptomyces coelicolor A3(2)
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: AL645882.2
Compounds
  • coelibactin
Species Streptomyces coelicolor A3(2) [taxonomy]
References
Chemical products information
coelibactin
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAC17498.1
  • SCO7681
 8504461 - 8506122 (-) putative AMP-binding ligase
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  • CAC17499.1
  • SCO7682
 8506283 - 8512972 (+) putative non-ribosomal peptide synthase
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  • CAC17500.1
  • SCO7683
 8512969 - 8518497 (+) putative non-ribosomal peptide synthase
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  • CAC17501.1
  • SCO7684
 8518494 - 8519645 (+) conserved hypothetical protein
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  • CAC17502.1
  • SCO7685
 8519642 - 8521675 (+) conserved hypothetical protein
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  • CAC17503.1
  • SCO7686
 8521684 - 8522919 (+) putative cytochrome P450
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  • CAC17504.1
  • SCO7687
 8522916 - 8523749 (+) putative thioesterase
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  • CAC17505.1
  • SCO7688
 8523760 - 8524488 (+) conserved hypothetical protein
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  • CAC17506.1
  • SCO7689
 8524521 - 8526347 (+) putative ABC transporter ATP-binding protein
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  • CAC17507.1
  • SCO7690
 8526344 - 8528107 (+) putative ABC transporter ATP-binding protein
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  • CAC17508.1
  • SCO7691
 8528166 - 8529581 (+) putative lyase
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
SCO7682
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: cysteine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
SCO7683
Module ?
Specificity: cysteine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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