BGC0000326: isocomplestatin biosynthetic gene cluster from Streptomyces lavendulae
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Location: 1 - 55,972 nt. (total: 55,972 nt).
This entry is originally from NCBI GenBank AF386507.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000326
Short description isocomplestatin biosynthetic gene cluster from Streptomyces lavendulae
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: AF386507.1
Compounds
  • isocomplestatin
Species Streptomyces lavendulae [taxonomy]
References
Chemical products information
isocomplestatin
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C61H45Cl6N7O15
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAK81822.1
 2020 - 3066 (+) transcriptional regulator
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  • AAK81823.1
 3491 - 5617 (+) ABC transporter
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  • AAK81824.1
 5664 - 12014 (+) peptide synthetase
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  • AAK81825.1
 12011 - 16606 (+) peptide synthetase
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  • AAK81826.1
 16705 - 31401 (+) peptide synthetase
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  • AAK81827.1
 31439 - 37933 (+) peptide synthetase
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  • AAK81828.1
 37938 - 38159 (+) hypothetical protein
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  • AAK81829.1
 38198 - 39475 (+) integral membrane ion antiporter
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  • AAK81830.1
 39504 - 40997 (+) non-heme halogenase
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  • AAK81831.1
 41015 - 42208 (+) P450-related oxidase
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  • AAK81832.1
 42222 - 43493 (+) P450-related oxidase
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  • AAK81833.1
 43538 - 43756 (+) ferredoxin
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  • AAK81834.1
 43834 - 44952 (-) glycolate oxidase
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  • AAK81835.1
 44939 - 45955 (-) hydroxyphenyl pyruvate dioxygenase
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  • AAK81836.1
 46193 - 47539 (+) aminotransferase
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  • AAK81837.1
 47536 - 48684 (+) prephenate dehydrogenase
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
AAK81824.1
Module ?
Specificity: p-hydroxybenzoylformic acid
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: tryptophan
Evidence for specificity:
  • Structure-based inference
AAK81825.1
Module ?
Specificity: 4-hydroxyphenylglycine
Evidence for specificity:
  • Structure-based inference
AAK81826.1
Module ?
Specificity: 4-hydroxyphenylglycine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: 4-hydroxyphenylglycine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: tyrosine
Evidence for specificity:
  • Structure-based inference
AAK81827.1
Module ?
Specificity: 4-hydroxyphenylglycine
Evidence for specificity:
  • Structure-based inference
Module ?
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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