LOCUS       BGC0000329             21538 bp    DNA     linear   BCT 22-JUL-2014
DEFINITION  Pseudomonas corrugata strain CFBP 5454 transcriptional activator
            protein (pcoR), putative membrane protein (rhtB), acyl-homoserine
            lactone synthase (pcoI), and RfiA (rfiA) genes, complete cds; pcoABC
            efflux system operon, complete sequence; putative
            diaminobutyrate-2-oxoglutarate transaminase protein, ABC transporter
            protein (crpE), and membrane fusion protein (crpD) genes, complete
            cds; and non ribosomal peptide synthetase (crpC) gene, partial cds.
ACCESSION   BGC0000329
VERSION     BGC0000329
KEYWORDS    .
SOURCE      Pseudomonas corrugata
  ORGANISM  Pseudomonas corrugata
            Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Pseudomonas.
COMMENT     On or before Jul 22, 2014 this sequence version replaced
            EF189721.2, KF192265.1.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 13:24:21
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 21538
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..21538
                     /db_xref="taxon:47879"
                     /mol_type="genomic DNA"
                     /organism="Pseudomonas corrugata"
                     /strain="CFBP 5454"
     protocluster    1..21538
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[15047:21536]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      15048..>21536
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..21538
                     /SMILES="NC(CO)C(=O)NC(C(C)CC)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="Autoind_synth"
                     /kind="neighbouring"
                     /product="NRPS"
                     /product="hserlactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..21538
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000329"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..21538
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="hserlactone"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="Autoind_synth"
                     /subregion_numbers="1"
                     /tool="antismash"
     protocluster    1..13252
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2478:3252]"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      2479..3252
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="2"
     cand_cluster    1..13252
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="2"
                     /tool="antismash"
     gene            486..1214
                     /gene="pcoR"
     CDS             486..1214
                     /codon_start=1
                     /gene="pcoR"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1197:autoinducer-binding transcriptional regulator,
                     (Score: 154.3; E-value: 5.8e-47)"
                     /gene_kind="regulatory"
                     /note="transcriptional regulator"
                     /product="transcriptional activator protein"
                     /protein_id="ABP88722.1"
                     /transl_table=11
                     /translation="MLKPISSHLFNLIQEVENNISGVSEEEYTEILGWIFSRLGIEKFA
                     YVHLEPTPFNNSKISIYSNYPSEWVDTYRKNSLYKSDPVMANTAITATPFFWNEIPAEI
                     DNNPEIFDQSASYGIKQGYTVPIHEPGRAFGSLHLSSEENDPDFPIIVRSNLFIIKTLS
                     VIANQYRPMETTIESNLKLSPREIEFLRWLALGKNYKEIGLIMNITERTVKFHAKQMTE
                     KMDCTNVKQAMIKAVQLNFV"
     gene            complement(1300..1912)
                     /gene="rhtB"
                     /note="orf1"
     CDS             complement(1301..1912)
                     /codon_start=1
                     /gene="rhtB"
                     /gene_functions="transport (smcogs)
                     SMCOG1116:Homoserine/threonine efflux protein (Score: 59.1;
                     E-value: 7.6e-18)"
                     /gene_kind="transport"
                     /note="putative threonine efflux protein; amino acid
                     transport and metabolism"
                     /product="putative membrane protein"
                     /protein_id="ABP88723.1"
                     /transl_table=11
                     /translation="MDDLMSYIALSLMTVLLVPGPTNSLLLQTGIKRGLNARSMRYVVA
                     EWLAYVIQMTMWGVSIDLLMTEHSWVVIATKFFAVCFLFYISLKLWFSVKDHLPGNSAG
                     ISVPDLFVATLTNPKGLFFVSFVAPPGTFLSLSNYLPFMMLFTAVIFPVGLAWIAIGAF
                     CGRKLHTIVSGRFLSRAISLVIGLFACGMLFNIASQVVFA"
     gene            2479..3252
                     /gene="pcoI"
     CDS             2479..3252
                     /codon_start=1
                     /gene="pcoI"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /note="AHL synthase"
                     /product="acyl-homoserine lactone synthase"
                     /protein_id="ABP88724.1"
                     /sec_met_domain="Autoind_synth (E-value: 1.7e-38, bitscore:
                     121.5, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYSSCIHHFFGVSTCIASYSKIPTQTLQQILAIRKTAFIDRKKW
                     DIASYQGSDYERDEYDDPDAVYIYAQTQGRVSGCVRLRASNKPTLMSGALSFILPADNI
                     RPHSHTCWEATRFALSADKTLAGEVTQANIDARTAALFLSMIKFAQLQNIDTYEIVVDT
                     MMEKILKRSGWTVDRHNTALGSKGETIIYGTLPCTPDTYNEVLNKNAVQTITAYEQFFM
                     TNRSSDISHQPFDIDQTHIDRNIPARKQMHTELHL"
     gene            3285..4151
                     /gene="rfiA"
     CDS             3285..4151
                     /codon_start=1
                     /gene="rfiA"
                     /note="LuxR transcriptional regulator; required for
                     lipodepsipeptide production"
                     /product="RfiA"
                     /protein_id="ACV88180.1"
                     /transl_table=11
                     /translation="MNLQRLFPHVGKVIASTGSRNFPRLLHDLILTEIPVDATHITEQR
                     IGSSQLSEPSTSSIGGVGMDSACIDAVMDAHTAKPFFLAEDIFFEDSTPQKVPNFSRCL
                     LNREQSESPSSHNTTTQLHLATRKNGIRYVLSVYRSPFSSGFTAQEHALLKDFSCLLLP
                     MVEEHVAAMVPAEVSRQDACLPLEGSENGGMEALRQRFADRLALSGLSLSSRETEVCVG
                     LLAGRTAPELAEQLNLKVNTVESYLKRAAIKMGIGGRRSLIRWMHSMDATPSAIEWNGI
                     SAIRQAV"
     gene            complement(4209..7292)
                     /gene="pcoC"
                     /operon="pcoABC efflux system"
     CDS             complement(4209..7292)
                     /codon_start=1
                     /gene="pcoC"
                     /gene_functions="transport (smcogs)
                     SMCOG1049:AcrB/AcrD/AcrF family protein (Score: 941.6;
                     E-value: 8.4e-285)"
                     /gene_kind="transport"
                     /note="resistance-nodulation-cell division transporter"
                     /operon="pcoABC efflux system"
                     /product="PcoC"
                     /protein_id="ACV88181.1"
                     /transl_table=11
                     /translation="MNISALSIRYPVPAVMLFILLTLFGLLGFGKLAIQDFPDMDLPVV
                     VISASLEGAAPEQLETEVARKIEDKLTSLRLLKHVTTVITDGAVSISVSFDIDKDGNEA
                     LNEVRNAVDSAMPQLPASLDTPSVSRLTTSASPLLTYVIASDALDEEALSWFVDNELSK
                     QLLSVPGVALISRIGGVDREVQVNLDPALMAGLGIRVADVAAQLRAMQKDNSGGQGNLG
                     SGQQAVRTLGAIDDPAVLGTIDIPSGDGRLLALSQLADIRDTHAERSSRAFRDGKPVIG
                     FQITRSLGFSDIGVANDVRKRMTEFVQQHPNVRIDEASDTVKAVLANYHDSMNLLYEGM
                     LLAVLVVWWFLRDWRATLIVATALPLSIIPTFGVMYLAGFTLNAVSLLALALVIGVLVD
                     DAIVEIENIARHLRMGKTPLQAATEAADEIGLAVLATTATLVAVFLPTAFMGGVAGKLF
                     RQFGVTASVALLFSLLVARVLTPMMAAYFLKAKTDTAHDGPLMTRYLGWIHASLSRRKT
                     TMVLASLFFIGALALVPLLPTSFLPAQDVGRSRITLELPPGTTLEQTTGMALQASERLS
                     EMPQVKHVFISVGTASSSGAGPADITGAGDAILTVDLVDRNQRDLKQVQVEAQMRDALR
                     TLPGVRINVGGDGSGEKLNIVLASDDGDLLERTASALEPQLRELHGIGNVTSSSALQRP
                     EIQMRPDFARAAELGITSQEIADTLRMATYGEYSSQLGKINLSQRQVDVRVRMDSLLRD
                     DLQSINQLRVTGRDGQVTLSSLGDISMGSGPAQISRLDRLRNITLSIELNGRNLGEVMA
                     EASQLPAMRNLPPEVKRVEQGELQLMTELFGSFSLAMAIGVFCIYSVLVLLFHDFLQPA
                     TILSALPLSLGGALVALLVCNFSFSLPSVIGLLMLMGIVTKNSILLVEYAIMARRDYGL
                     GRYDALVDACHKRARPILMTTIAMGAGMLPTALGMGEDPSFRQPMAVVVMGGLLTSTLL
                     SLLVVPVIFTYVDDVLEWLKLRTRRSTGERMEGQNTRA"
     operon          complement(4209..9819)
                     /note="resistence-nodulation-cell division transporter
                     system"
                     /operon="pcoABC efflux system"
     gene            complement(7289..8449)
                     /gene="pcoB"
                     /operon="pcoABC efflux system"
     CDS             complement(7289..8449)
                     /codon_start=1
                     /gene="pcoB"
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 171.2; E-value:
                     4.9e-52)"
                     /gene_kind="transport"
                     /note="periplasmic membrane fusion protein"
                     /operon="pcoABC efflux system"
                     /product="PcoB"
                     /protein_id="ACV88182.1"
                     /transl_table=11
                     /translation="MANRPAAGSAPDIEWRGRVRPTLRKILLTIAVVAVVAILMTFRRG
                     AEPVAAAPSISSLSVEVVQARPQLWPQLLFANGALAPWQEAVINAETSGLRIASLEADV
                     GSRVKKGQLLATLASDTVLAEESKQKALVAQAVANLEQARSNDRRARVVGQGGALSEQQ
                     REDYRIKVALAEADLAGARAELQSTRIRLRQTRIVAVDDGIISARTALLGKVLSAGDEL
                     FRLVRDGRIEWQAELDARQLAQVQVGQVARLTLPGGQSLEGWVRLVSPTLNTKTSRALV
                     YISLPTGSPAQAGMYASGQIELAPREALTVPDTAVILRDGRSYVFTLNDDMHVVQRPVV
                     VGRRMHEAVEILSGLDDQGARIVRAGGAFLNDGASVTLVQSQVAQP"
     gene            complement(8392..9819)
                     /gene="pcoA"
                     /operon="pcoABC efflux system"
     CDS             complement(8392..9819)
                     /codon_start=1
                     /gene="pcoA"
                     /gene_functions="transport (smcogs) SMCOG1076:RND efflux
                     system, outer membrane lipoprotein, (Score: 372.6; E-value:
                     4e-113)"
                     /gene_kind="transport"
                     /note="outer membrane protein"
                     /operon="pcoABC efflux system"
                     /product="PcoA"
                     /protein_id="ACV88183.1"
                     /transl_table=11
                     /translation="MHVFKPRANLLLATLCAVLSGCVLGPDYRVPAVPVAAKWQAPLPH
                     GASVAALADWWQQFDDPALAELLRLAEADSPSMDQAWANIALARATADSDAADAMPRID
                     GQLSKGRGGQQTGSQRLGGSGSSAALDAAWEIDLFGKLRRNNEAARSRVEARVDDWHDA
                     RVSLAAQVGDYYVQYRGCQKLVLAYRDQAQSQQDTARITRQSFGAGFTSSADAALADAS
                     AASSAAALVQQQSECEVLLKSLVALTGGDEERLIGVLGKTPAQLPEPAGLNVQQIPADM
                     LRQRPDVASSERELAAANAEIGVAQADRLPSLSLSGTFSVGNTVGQHNRSWSLGPVLSV
                     PLFDGGKRRAAVDGAKASYDAALAVYRQTLRTSVMEVEQALVRLDAARRRESDVERSTA
                     GFRESFEAIDRNWQAGSVSLLDRETARRQALTAEIELITLQQDQVRYWIALYKALGGGW
                     QTGQPLARHPTSNGEGV"
     CDS             10218..11558
                     /NRPS_PKS="Domain: Aminotran_3 (26-367). E-value: 1e-91.
                     Score: 299.3. Matches aSDomain:
                     nrpspksdomains_AHY86404.1_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 443.5;
                     E-value: 1.2e-134)"
                     /gene_kind="biosynthetic-additional"
                     /note="Orf10"
                     /product="putative diaminobutyrate-2-oxoglutarate
                     transaminase protein"
                     /protein_id="AHY86404.1"
                     /sec_met_domain="Aminotran_3 (E-value: 9.8e-94, bitscore:
                     303.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEALSYLENVESNARTYAQTFQRLFVSGKGMRIKDASGQEFLDCL
                     SNAGTLALGHNPPEVRDAVMTFLAGDHLQQALDLATPAKHAFVQELFSTLPANMRETSK
                     ILFCGPSGSDAVEAAIKLARHYTRRSPLMAFHGGYHGMTAGALSAMGKLSPKTGDGLIA
                     QGTHFLPFPYRFRCPFGTDGEHTDQLSIDYIRTVLSDPEGGVAKPAAVIVEVVQGEGGC
                     IPASANWLRALREITLEQEILLIVDEVQTGLGRTGSTFAIEHAGIVPDILVLSKAIGGG
                     YPLAVVVYAEHLDTWGPGMHAGTFRGNQVAMVAGAATMRQIRKDNLVANAARMGERLEN
                     GLQDIAQRFSFIGDIRGRGLMIGVEITQPTTTQRAGQADGALAHAIKLKCFDNGLMMET
                     GGRHGAVLRFLPPLTITEGEVDMVLDRFEQSLGKIVETCPYAARETV"
     aSDomain        10296..11318
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AHY86404.1_Aminotran_3.1"
                     /evalue="1.00E-91"
                     /label="AHY86404.1_Aminotran_3.1"
                     /locus_tag="AHY86404.1"
                     /protein_end="367"
                     /protein_start="26"
                     /score="299.3"
                     /tool="antismash"
                     /translation="SGKGMRIKDASGQEFLDCLSNAGTLALGHNPPEVRDAVMTFLAGD
                     HLQQALDLATPAKHAFVQELFSTLPANMRETSKILFCGPSGSDAVEAAIKLARHYTRRS
                     PLMAFHGGYHGMTAGALSAMGKLSPKTGDGLIAQGTHFLPFPYRFRCPFGTDGEHTDQL
                     SIDYIRTVLSDPEGGVAKPAAVIVEVVQGEGGCIPASANWLRALREITLEQEILLIVDE
                     VQTGLGRTGSTFAIEHAGIVPDILVLSKAIGGGYPLAVVVYAEHLDTWGPGMHAGTFRG
                     NQVAMVAGAATMRQIRKDNLVANAARMGERLENGLQDIAQRFSFIGDIRGRGLMIGVEI
                     T"
     gene            complement(11854..13815)
                     /gene="crpE"
     CDS             complement(11854..13815)
                     /codon_start=1
                     /gene="crpE"
                     /gene_functions="resistance (resist) macB (Score: 712;
                     E-value: 3.1e-216)"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 206.1; E-value:
                     1e-62)"
                     /gene_kind="transport"
                     /note="CrpE"
                     /product="ABC transporter protein"
                     /protein_id="AHY86401.1"
                     /transl_table=11
                     /translation="MTRPLLELEGITRSFQAGEKAFIALKDINLTINAGEIVAITGASG
                     SGKSTLMNVLGCLDHPSSGSYKVDGRETGSMDDHELAELRRDHFGFIFQRYHLLPHLSA
                     LHNVEMPAIYAGAAESQRHNRAGELLGRLGLTGHLANRPSQLSGGQQQRVSIARALMNG
                     GEIILADEPTGALDTASGKEVMKILLELNAAGHTVIIVTHDEKVAAYAQRIIEIRDGEI
                     VSDRANPRRSMEDQPPQGTPPAKVKPSNRLLASFGLFSEAFNMAWVALISHRMRTLLTM
                     LGIIIGITSVVSIVAIGEGVKQYVLKDIEAIGSNTIEIMPGADWGDSRSTAIETLVLSD
                     VTALSDLYYIDSATPNLGRNLLLRYQNIDVNATVNGVSESYFQVRGIKIGSGVAFNKDD
                     SRRQSQVVVIDHNTSQRLFGSHTDPLGKVILVDNLPCTVIGVTEDRKSVFNTSKNLNIW
                     MPYETAAGRLLGQRFLDSITVRIKDGQPSKLVEDNVVKLLTQRHGIKDFFTYNLDSVMQ
                     TVQKTSQSLALLLSLIAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARQSDIRQQ
                     FLVEAVMVCLLGGTIGIGLSFSIGYVFSIFVKEWQMVFSMGSIITAVVCSTLIGIVFGF
                     VPARNAARLDPINALARD"
     gene            complement(13818..14969)
                     /gene="crpD"
     CDS             complement(13818..14969)
                     /codon_start=1
                     /gene="crpD"
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 285.7; E-value:
                     7.8e-87)"
                     /gene_kind="transport"
                     /note="CrpD"
                     /product="membrane fusion protein"
                     /protein_id="AHY86402.1"
                     /transl_table=11
                     /translation="MEKSKFRKIAIVLVLVVVTGLVFYSAQSPGKPPEYLTATVERTDI
                     ENAVLATGTLQGVKQVDVGAQVSGQLKSLKVKLGDKVKKGQWLAEIDPLLAQNALRQAL
                     VNEENLKAKRQATAAQLKDAKATYDRYKVLQPDDAISKQEFETAESNYKVEAANLLSLD
                     AQIKDAQIQVETARVNLAYTHIVAPIDGYVVGIVTQEGQTVIAEQLAPVLLKLADLDTM
                     TVKAQVSEADVIHIVPGQEVYFTILGEAEKRYYATLRGTEPAPQNFLETQNAGTPKQNT
                     AVFYNSLFDVPNPDHRLRISMTAQVRIVLDKAKAVLTVPVAALGAKNQDGSYVVRVLDA
                     EGKAQPRNVQTGINNNVRAEIKDGLAEGDKVVIGEPTPAVAGA"
     CDS             complement(15048..>21538)
                     /NRPS_PKS="Domain: AMP-binding (1-320). E-value: 1.7e-88.
                     Score: 288.8. Matches aSDomain:
                     nrpspksdomains_crpC_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (430-496). E-value: 4.1e-29. Score:
                     92.5. Matches aSDomain: nrpspksdomains_crpC_PCP.1"
                     /NRPS_PKS="Domain: Condensation_Dual (544-838). E-value:
                     1.3e-137. Score: 449.8. Matches aSDomain:
                     nrpspksdomains_crpC_Condensation_Dual.1"
                     /NRPS_PKS="Domain: AMP-binding (1001-1396). E-value:
                     3.8e-106. Score: 346.9. Matches aSDomain:
                     nrpspksdomains_crpC_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1507-1574). E-value: 3.3e-24.
                     Score: 76.8. Matches aSDomain: nrpspksdomains_crpC_PCP.2"
                     /NRPS_PKS="Domain: Thioesterase (1594-1853). E-value:
                     5e-29. Score: 94.2. Matches aSDomain:
                     nrpspksdomains_crpC_Thioesterase.1"
                     /codon_start=3
                     /gene="crpC"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     157.2; E-value: 1.3e-47)"
                     /gene_kind="biosynthetic"
                     /note="CrpC"
                     /product="non ribosomal peptide synthetase"
                     /protein_id="AHY86403.1"
                     /sec_met_domain="PP-binding (E-value: 3.6e-15, bitscore:
                     45.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3.1e-47, bitscore:
                     150.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 9.2e-116, bitscore:
                     376.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.7e-08, bitscore: 23.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.2e-12, bitscore:
                     37.1, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRLAYMLESSAPAVVLTQRALQMNLPATAARVIVLEDEDFATQP
                     TGNPQVQGLRADHLAYVIYTSGSTGLPKGVMNEHGAVVNRLLWMQDAYTLSAADAVLQK
                     TPFSFDVSVWEFFWPLFTGARLVMARPGGHRDPAYLREVIQTQGITTLHFVPSMLDVFL
                     AHGEAGECEGLRQVMCSGEALPGHLVRRFKAQLPRTSLHNLYGPTEAAVDVTAWDCSGA
                     ETPDSTPIGKPIANTRIYLLDAHQQPVPMGVAGEIYIGGVQVARGYLHRPELTAERFLD
                     DPFSERPNARMYRTGDLGRYLADGNIDYLGRNDDQVKIRGFRIELGEIEAKLARHAAIK
                     EAVVLAREDVPGAKRLVAYFTVHGDEFNIEIESLRAQLQAQLPEYMVPAAYVRLDALPL
                     TPNGKLNRKALPAPDQASVITREYEAPQGAVETTLAQLWAELLKVERVGRHDHFFELGG
                     HSLLAVTLIERMRQSGLSADVRVLFGQPTLAALAAAVGGATEIVVPDNGIVPDCEQITP
                     QMLPLADLSQREIDAVVAGVPGGMSNVQDIYALAPLQEGILYHHLASQQGDLYVQQAMF
                     NFKDRARLDDFVNALQGVIDRHDILRTAVLWEGLREPVQVVLRQAPLAVQTCMVEPGQD
                     VGAQLRERFDPRHYRLDVRQAPMMRLACAYDDEHQRWVALLLFHHIALDHTALEVIQHD
                     MQAYLLGQQAQLGDAVPYRNYVAQARLGVTQSAHEAFFRDMLQDIQEPTLPFGLQDVQG
                     DSHVIEQARLGVDDSLNRRLRTQSRLLGVSAASLHHLAWARVVGAVSGREDVVFGTVLM
                     GRMQGGEGADRALGLFINTLPLRVDVGVDGARAGVKTTHARLTALLGHEHASLALAQRC
                     SGVATSTPLFSALLNYRHTATQVTQEAQSAWNGIEGLGGEEWSNYPLSLNVDDLGEAFV
                     LTALAESRIGAERICGYMHTALESLVDALEHTPEVPLRELAILPAAERRQLLVDFNATD
                     TVYPREETVHGLFEAQVKARPEGIALQHGAQQLTYRELHERANHLAHCLLERGVQPGSR
                     VAIMLNRSFELVISELAILKCAAVYVPLDHHAPEERQRFMLQDSAAVLVLTTSDRGLPE
                     DMPRLDLDTLQVIQAARPAVFPGQTSDTPAYIMYTSGSTGHPKGVIVPHLAIGRLAINN
                     GYADFGVQDHVAFASNPAFDASTMEVWGALLNGGRVVIIDHETLLSPTQFAQALTDAEV
                     SVLFVTTAMFNQYLVLIPDALAGLRILLCGGERGDPASFRRLLAHAPSLRLVHCYGPTE
                     TTTFATTHVVTAVPHGATSVPIGRPIANTRVYILDAARQPVPVGVAGEIHIGGVGVALG
                     YLNRPDLTEERFIADPFSDSGTARLYRSGDLGRWLPDGTIEYLDRNDGQVKIRGFRIEL
                     GEIEARLHECHGVREALVVAREDSPGDKRLIAYYTEHENAGGLDADVLRAQLRSVLPEY
                     MIPAAYVKLTALPLTLNGKVNTGALPVPELHAYGSQGYEAPQGDLEVMLAGLWADVLKL
                     EQVGRHDNFFELGGHSLLAIRLVGLLAQANLTVSLAELFQHESVASMASMLQTRTEDAQ
                     VKEAIVPVRTTGQQNPLFLVHEFSGLDLYFPTLGKHIDPDIPVYGLPAVEWGEPQLQTM
                     ECMASRLVGIIRSVQPQGPYRLAGWSFGGVLAYETAIQLIGLDEEVEFVGLIDSYLPRL
                     VDQGRSRWALDEAHKLHLLDRCDVFWRAALPGEEVLAAILAKLADLQGQLDRFDFEGLV
                     QHCRDDAVLPAELAVYSAEQLWQYLDREVAHGHALAHYMVYPISVPVHLLVAEERQDDA
                     PEHSGYLGWDAVLPTSQLHCVKVPGNHQSMMQAPHVQALGQALSTELHTAASRPAPLPK
                     SGYQPLLTIQGGRADRAPIFCVPGAGDSVTGFIGLTDAFGPDWPIHGLQHRGLDGSTEP
                     FSLVETAAQAYLEAIDKVQPEGPVHLLGHSFGGWIVFEMAARLHARGRKVASLTLIDSE
                     SPGGNGVVGRPYTGTGVLNRLIEAMQLASGKSLGIDATVFGAQDDSAQMRLLHAGMVRA
                     GMLPQRSAVDSMRGPARAFGTALRTVYQPQHQYTGPVRLVLANDPTLDTAGNKREQQEM
                     IEGWRKHVPDLSIWYGPGNHFTILKAPHVHNLAAWWQDGLPMLDEEEASDYV"
     gene            complement(15048..>21538)
                     /gene="crpC"
     CDS_motif       complement(15609..15683)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0021"
                     /evalue="1.10E-13"
                     /label="NRPS-te1"
                     /locus_tag="crpC"
                     /protein_end="1976"
                     /protein_start="1951"
                     /score="43.4"
                     /tool="antismash"
                     /translation="QPEGPVHLLGHSFGGWIVFEMAARL"
     CDS_motif       complement(15837..15863)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0020"
                     /evalue="2.70E-01"
                     /label="NRPS-beforete1"
                     /locus_tag="crpC"
                     /protein_end="1900"
                     /protein_start="1891"
                     /score="4.8"
                     /tool="antismash"
                     /translation="PIFCVPGAG"
     aSDomain        complement(15978..16754)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_crpC_Thioesterase.1"
                     /evalue="5.00E-29"
                     /label="crpC_Thioesterase.1"
                     /locus_tag="crpC"
                     /protein_end="1853"
                     /protein_start="1594"
                     /score="94.2"
                     /tool="antismash"
                     /translation="PLFLVHEFSGLDLYFPTLGKHIDPDIPVYGLPAVEWGEPQLQTME
                     CMASRLVGIIRSVQPQGPYRLAGWSFGGVLAYETAIQLIGLDEEVEFVGLIDSYLPRLV
                     DQGRSRWALDEAHKLHLLDRCDVFWRAALPGEEVLAAILAKLADLQGQLDRFDFEGLVQ
                     HCRDDAVLPAELAVYSAEQLWQYLDREVAHGHALAHYMVYPISVPVHLLVAEERQDDAP
                     EHSGYLGWDAVLPTSQLHCVKVPGNHQSMMQAPHVQA"
     aSModule        complement(15978..19904)
                     /complete
                     /domains="nrpspksdomains_crpC_Condensation_Dual.1"
                     /domains="nrpspksdomains_crpC_AMP-binding.2"
                     /domains="nrpspksdomains_crpC_PCP.2"
                     /domains="nrpspksdomains_crpC_Thioesterase.1"
                     /final_module
                     /locus_tags="crpC"
                     /monomer_pairings="Ile -> Ile"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(16506..16580)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0019"
                     /evalue="6.60E-15"
                     /label="NRPS-te1"
                     /locus_tag="crpC"
                     /protein_end="1677"
                     /protein_start="1652"
                     /score="47.3"
                     /tool="antismash"
                     /translation="QPQGPYRLAGWSFGGVLAYETAIQL"
     CDS_motif       complement(16725..16754)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0018"
                     /evalue="2.50E-01"
                     /label="NRPS-beforete1"
                     /locus_tag="crpC"
                     /protein_end="1604"
                     /protein_start="1594"
                     /score="4.9"
                     /tool="antismash"
                     /translation="PLFLVHEFSG"
     aSDomain        complement(16815..17015)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_crpC_PCP.2"
                     /evalue="3.30E-24"
                     /label="crpC_PCP.2"
                     /locus_tag="crpC"
                     /protein_end="1574"
                     /protein_start="1507"
                     /score="76.8"
                     /tool="antismash"
                     /translation="VMLAGLWADVLKLEQVGRHDNFFELGGHSLLAIRLVGLLAQANLT
                     VSLAELFQHESVASMASMLQTR"
     CDS_motif       complement(16875..16904)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0017"
                     /evalue="1.00E+01"
                     /label="C4_dual_169-182"
                     /locus_tag="crpC"
                     /protein_end="1554"
                     /protein_start="1544"
                     /score="-0.1"
                     /tool="antismash"
                     /translation="LLAQANLTVS"
     CDS_motif       complement(17319..17384)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0016"
                     /evalue="1.30E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="crpC"
                     /protein_end="1406"
                     /protein_start="1384"
                     /score="33.3"
                     /tool="antismash"
                     /translation="YLDRNDGQVKIRGFRIELGEIE"
     aSDomain        complement(17349..18533)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_crpC_AMP-binding.2"
                     /evalue="3.80E-106"
                     /label="crpC_AMP-binding.2"
                     /locus_tag="crpC"
                     /protein_end="1396"
                     /protein_start="1001"
                     /score="346.9"
                     /specificity="substrate consensus: Ile"
                     /tool="antismash"
                     /translation="FEAQVKARPEGIALQHGAQQLTYRELHERANHLAHCLLERGVQPG
                     SRVAIMLNRSFELVISELAILKCAAVYVPLDHHAPEERQRFMLQDSAAVLVLTTSDRGL
                     PEDMPRLDLDTLQVIQAARPAVFPGQTSDTPAYIMYTSGSTGHPKGVIVPHLAIGRLAI
                     NNGYADFGVQDHVAFASNPAFDASTMEVWGALLNGGRVVIIDHETLLSPTQFAQALTDA
                     EVSVLFVTTAMFNQYLVLIPDALAGLRILLCGGERGDPASFRRLLAHAPSLRLVHCYGP
                     TETTTFATTHVVTAVPHGATSVPIGRPIANTRVYILDAARQPVPVGVAGEIHIGGVGVA
                     LGYLNRPDLTEERFIADPFSDSGTARLYRSGDLGRWLPDGTIEYLDRNDGQVKIR"
     CDS_motif       complement(17472..17561)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0015"
                     /evalue="1.10E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="crpC"
                     /protein_end="1355"
                     /protein_start="1325"
                     /score="52.8"
                     /tool="antismash"
                     /translation="PVGVAGEIHIGGVGVALGYLNRPDLTEERF"
     CDS_motif       complement(17676..17699)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0014"
                     /evalue="2.50E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="crpC"
                     /protein_end="1287"
                     /protein_start="1279"
                     /score="4.8"
                     /tool="antismash"
                     /translation="YGPTETTT"
     CDS_motif       complement(18069..18128)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0013"
                     /evalue="5.30E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="crpC"
                     /protein_end="1156"
                     /protein_start="1136"
                     /score="28.2"
                     /tool="antismash"
                     /translation="AYIMYTSGSTGHPKGVIVPH"
     CDS_motif       complement(18306..18347)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0012"
                     /evalue="1.30E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="crpC"
                     /protein_end="1077"
                     /protein_start="1063"
                     /score="12.3"
                     /tool="antismash"
                     /translation="LAILKCAAVYVPLD"
     CDS_motif       complement(18909..18983)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0011"
                     /evalue="6.90E-12"
                     /label="C67_dual_14fromHMM"
                     /locus_tag="crpC"
                     /protein_end="876"
                     /protein_start="851"
                     /score="37.6"
                     /tool="antismash"
                     /translation="ARLTALLGHEHASLALAQRCSGVAT"
     aSDomain        complement(19023..19904)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_crpC_Condensation_Dual.1"
                     /domain_subtypes="Condensation_Dual"
                     /evalue="1.30E-137"
                     /label="crpC_Condensation_Dual.1"
                     /locus_tag="crpC"
                     /protein_end="838"
                     /protein_start="544"
                     /score="449.8"
                     /tool="antismash"
                     /translation="QDIYALAPLQEGILYHHLASQQGDLYVQQAMFNFKDRARLDDFVN
                     ALQGVIDRHDILRTAVLWEGLREPVQVVLRQAPLAVQTCMVEPGQDVGAQLRERFDPRH
                     YRLDVRQAPMMRLACAYDDEHQRWVALLLFHHIALDHTALEVIQHDMQAYLLGQQAQLG
                     DAVPYRNYVAQARLGVTQSAHEAFFRDMLQDIQEPTLPFGLQDVQGDSHVIEQARLGVD
                     DSLNRRLRTQSRLLGVSAASLHHLAWARVVGAVSGREDVVFGTVLMGRMQGGEGADRAL
                     GLFINTLPLRVDV"
     CDS_motif       complement(19032..19127)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0010"
                     /evalue="1.40E-19"
                     /label="C5_dual_260-291"
                     /locus_tag="crpC"
                     /protein_end="835"
                     /protein_start="803"
                     /score="61.9"
                     /tool="antismash"
                     /translation="DVVFGTVLMGRMQGGEGADRALGLFINTLPLR"
     CDS_motif       complement(19365..19406)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0009"
                     /evalue="6.80E-07"
                     /label="C4_dual_169-182"
                     /locus_tag="crpC"
                     /protein_end="724"
                     /protein_start="710"
                     /score="21.7"
                     /tool="antismash"
                     /translation="PYRNYVAQARLGVT"
     CDS_motif       complement(19440..19505)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0008"
                     /evalue="3.10E-08"
                     /label="C3_dual_135-156"
                     /locus_tag="crpC"
                     /protein_end="699"
                     /protein_start="677"
                     /score="26.4"
                     /tool="antismash"
                     /translation="FHHIALDHTALEVIQHDMQAYL"
     CDS_motif       complement(19716..19829)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0007"
                     /evalue="1.50E-20"
                     /label="C2_dual_024-063"
                     /locus_tag="crpC"
                     /protein_end="607"
                     /protein_start="569"
                     /score="65.8"
                     /tool="antismash"
                     /translation="YVQQAMFNFKDRARLDDFVNALQGVIDRHDILRTAVLW"
     CDS_motif       complement(19854..19895)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0006"
                     /evalue="2.20E-06"
                     /label="C1_dual_004-017"
                     /locus_tag="crpC"
                     /protein_end="561"
                     /protein_start="547"
                     /score="20.0"
                     /tool="antismash"
                     /translation="YALAPLQEGILYHH"
     aSDomain        complement(20049..20246)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_crpC_PCP.1"
                     /evalue="4.10E-29"
                     /label="crpC_PCP.1"
                     /locus_tag="crpC"
                     /protein_end="496"
                     /protein_start="430"
                     /score="92.5"
                     /tool="antismash"
                     /translation="ETTLAQLWAELLKVERVGRHDHFFELGGHSLLAVTLIERMRQSGL
                     SADVRVLFGQPTLAALAAAVG"
     aSModule        complement(20049..21533)
                     /complete
                     /domains="nrpspksdomains_crpC_AMP-binding.1"
                     /domains="nrpspksdomains_crpC_PCP.1"
                     /locus_tags="crpC"
                     /monomer_pairings="Ser -> Ser"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(20457..20510)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0005"
                     /evalue="7.20E+00"
                     /label="C5_LCL_267-296"
                     /locus_tag="crpC"
                     /protein_end="360"
                     /protein_start="342"
                     /score="-0.7"
                     /tool="antismash"
                     /translation="VVLAREDVPGAKRLVAYF"
     CDS_motif       complement(20547..20612)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0004"
                     /evalue="6.60E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="crpC"
                     /protein_end="330"
                     /protein_start="308"
                     /score="40.4"
                     /tool="antismash"
                     /translation="YLGRNDDQVKIRGFRIELGEIE"
     aSDomain        complement(20577..21533)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_crpC_AMP-binding.1"
                     /evalue="1.70E-88"
                     /label="crpC_AMP-binding.1"
                     /locus_tag="crpC"
                     /protein_end="320"
                     /protein_start="1"
                     /score="288.8"
                     /specificity="substrate consensus: Ser"
                     /tool="antismash"
                     /translation="DRLAYMLESSAPAVVLTQRALQMNLPATAARVIVLEDEDFATQPT
                     GNPQVQGLRADHLAYVIYTSGSTGLPKGVMNEHGAVVNRLLWMQDAYTLSAADAVLQKT
                     PFSFDVSVWEFFWPLFTGARLVMARPGGHRDPAYLREVIQTQGITTLHFVPSMLDVFLA
                     HGEAGECEGLRQVMCSGEALPGHLVRRFKAQLPRTSLHNLYGPTEAAVDVTAWDCSGAE
                     TPDSTPIGKPIANTRIYLLDAHQQPVPMGVAGEIYIGGVQVARGYLHRPELTAERFLDD
                     PFSERPNARMYRTGDLGRYLADGNIDYLGRNDDQVKIR"
     CDS_motif       complement(20700..20789)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0003"
                     /evalue="3.80E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="crpC"
                     /protein_end="279"
                     /protein_start="249"
                     /score="57.5"
                     /tool="antismash"
                     /translation="PMGVAGEIYIGGVQVARGYLHRPELTAERF"
     CDS_motif       complement(20901..20924)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0002"
                     /evalue="4.00E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="crpC"
                     /protein_end="212"
                     /protein_start="204"
                     /score="4.2"
                     /tool="antismash"
                     /translation="YGPTEAAV"
     CDS_motif       complement(21300..21359)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_crpC_0001"
                     /evalue="4.90E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="crpC"
                     /protein_end="79"
                     /protein_start="59"
                     /score="31.3"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGLPKGVMNEH"
ORIGIN
        1 atcgatatcg gcccgggagc gggctcccag gggggaaaag tggtggtttg cggaacgcca
       61 ggccacgtgg ccgactgtgc gcagagtcga actgcagggt tcctgaaaag cgcgtttcag
      121 cctcaatggt aaagcttttt caatgtcact ggccggatcg gaaaagttgt ctatactgcc
      181 ttccagttaa tcgtttcagt acgtgtagtt taactagcgg tctcgcagct catgttgtga
      241 ggccgtatct gccaggaggc acaatgacat taatccgcgg ttcaaaacag caacatcccg
      301 gggtgccgga acagcatgat caccccttgg caatccctct gatgagcgcg gagatccttc
      361 tcgccccgag cgccttcata gcgccgaaca ccctccaaag ccagctcact tccatttggc
      421 gactctaaag gtatagcgcc tgaccaagtc aaagtcttac attcaaattg tcgagctcgc
      481 tcattatgct caagcccatt tcaagccatc tgttcaattt gatccaagag gtggaaaaca
      541 atatctcagg cgtgagcgaa gaggagtaca ccgagatact cggctggata ttctccagac
      601 tgggaatcga aaaattcgcc tacgtccatc ttgagcccac accgttcaac aactcgaaga
      661 tttccatcta cagcaactac ccatccgaat gggtggacac ctaccgcaag aactcactct
      721 acaaatcaga cccggtcatg gccaacaccg ccatcaccgc gactcctttt ttctggaatg
      781 aaataccggc ggaaatcgac aacaatcccg agatattcga ccagtcagcc tcctatggca
      841 tcaaacaggg ttacaccgtc cccatccatg agcccggtcg agcattcggt tcccttcacc
      901 tgtcttcaga agagaatgac cccgactttc ccatcatcgt ccgctcgaat ctgttcatca
      961 tcaaaaccct cagcgtcatc gccaatcaat atcgccccat ggaaaccacc attgaaagca
     1021 acttgaaact atcccccaga gaaatagaat tcctgcgctg gctcgcgttg ggaaaaaact
     1081 ataaggagat aggcttgatc atgaatatta ccgaacgaac ggtaaagttt cacgccaagc
     1141 agatgaccga aaagatggac tgcaccaatg tcaagcaagc aatgatcaag gcagtacagc
     1201 taaacttcgt ttgacccctt cccttcatct actcgcgatt gcaggcgacg gtcctatggg
     1261 gacccgacgc catgcccgac gttaccgcaa atgcccgcct tcaggcgaat acaacctgcg
     1321 aggcgatgtt gaaaagcatg ccgcatgcga ataagccaat caccaacgaa atggcccgac
     1381 tcaaaaaccg gccggaaaca atagtgtgga gtttacgtcc acagaatgcc ccgatggcga
     1441 tccaggccag tccgaccgga aatattacag ctgtgaacag catcatgaat ggcaggtagt
     1501 tgctcagcga taaaaacgtt ccgggtggcg caacaaagga aacgaagaac aatcctttcg
     1561 gattggtcag cgtcgccaca aacaggtcag gcacactgat acccgccgag ttaccaggga
     1621 gatggtcttt taccgagaac catagcttca gggaaatata aaataaaaag cacacggcaa
     1681 aaaacttggt cgcaatgact acccaggaat gttcagtcat cagaagatca atggatactc
     1741 cccacatcgt catctgaatg acataagcca gccactctgc cacgacatac ctcatggagc
     1801 gagcattcag ccctctcttt attccggttt gcagcagcag tgagtttgtc ggtcccggaa
     1861 ccagcagcac tgtcatcagt gaaagcgcaa tataagacat aaggtcatcc atgccaggag
     1921 ccacgatggc tcatcttttc aggttcggac tggtctgctc ctacaacatc aactttttag
     1981 ttgtatgaca tcagaccaac tcttccacag ttagagcagt tacactaaag ccacgactgc
     2041 ttttcgcccc cggctcatac agtcgtttaa acttccacgc ctgggctcac ccctgctttt
     2101 ctaaaaaact tccacacctt tattacagcc aggttacttg cctcgaccca ggtgtcaatt
     2161 tttcgaccca cccattatca ggacgttatc gccgcttaag ccggccgtca aaaaacacgc
     2221 agtcgtcgac tatcagaaac cgccatactt ttacctgtaa gcgccatcta ccgccgactt
     2281 caagtcggta cttttttgga ctccagacga tactaaaaca ccctcctggc gcactctcca
     2341 cgaatacgat tcagcgcact gatcgggcaa ctaattagac tatacactct actaaacctc
     2401 accctgtact ttaggacagt tgaaatgatt tagtgcaaag ttaacagtag cctcatccac
     2461 aaccaagaaa cgtcattcat gaactactcc tcctgcattc atcacttttt cggcgtatct
     2521 acctgcattg catcttactc gaaaatccca acccaaacgt tgcaacagat acttgcaatt
     2581 cggaaaacag ccttcatcga tagaaagaaa tgggacattg caagttatca aggcagcgat
     2641 tacgaacggg atgaatatga cgatcctgat gcagtttaca tttatgctca gacccaaggg
     2701 cgggtctccg gttgtgtgcg tttacgcgcc tccaacaaac caaccctcat gagcggcgct
     2761 ttaagtttca tccttcccgc cgacaacatc aggcctcact cacacacttg ttgggaagct
     2821 accagatttg cactttcggc agataagacc ttagccggag aagtcaccca ggccaacata
     2881 gacgctcgca cggcggcact tttcctgtca atgataaagt ttgcccaact gcaaaatata
     2941 gacacctatg aaatcgtcgt tgacaccatg atggagaaaa tcctcaaacg atccgggtgg
     3001 acagtcgaca gacacaacac cgcgctgggt tcaaagggag aaaccatcat ctacggcaca
     3061 ctcccatgca cgcctgacac ttacaacgaa gtgctcaaca agaatgccgt ccagaccatc
     3121 accgcctacg aacaattctt tatgaccaac cgttcgtcag acatatccca tcaacccttt
     3181 gatatcgacc aaacacacat cgaccgaaat attccagcaa gaaaacagat gcacactgag
     3241 ttgcatctat aacaccaaga ctctggcatg aaattggaga aaggatgaac ctacaacgac
     3301 tattcccaca tgttggcaaa gtgattgcca gtactggaag ccgcaacttt cctcgtttgt
     3361 tgcacgacct gatacttacc gaaatacctg tcgatgcaac gcatattacc gagcaaagaa
     3421 taggatcgag ccaactctct gaacccagca cttccagcat cggtggtgtt ggtatggaca
     3481 gcgcctgcat cgacgctgtc atggatgcgc ataccgcaaa gccttttttc ctcgccgagg
     3541 atattttttt cgaggattcg accccacaaa aggtccccaa tttttcccgc tgcctgctca
     3601 atcgcgaaca atcggaaagc ccctccagtc acaacaccac cactcaattg cacctggcca
     3661 cacgtaaaaa cggcattcgt tatgtccttt ccgtataccg ctcacctttt tccagcggat
     3721 tcacggcaca ggaacatgcc ctgctgaaag atttttcctg ccttctttta cccatggtcg
     3781 aagagcatgt tgccgccatg gtgccagcgg aggtcagccg acaggacgct tgcctgccgt
     3841 tggaaggctc ggaaaacggc gggatggagg cattgcgcca gagatttgcc gaccggctgg
     3901 ctttatccgg gttgagcttg tcctcccgtg aaaccgaagt gtgtgtaggc ttgctggccg
     3961 gacgcacggc cccggaactg gccgagcaac tcaacctgaa agtcaacacc gtcgaaagtt
     4021 atctgaagcg tgctgccata aaaatgggca ttggtggacg ccgctcgctc atccgctgga
     4081 tgcactcgat ggatgccaca ccatcggcca tcgagtggaa tggtatttcc gcaattcgcc
     4141 aagccgtata gaacgttccc cccaaccttt gctcggtcat ctcaatcgag cgggtgttgg
     4201 gggatgattc atgcccgggt attctgaccc tccattcttt ccccggtcga tctgcgcgtg
     4261 cgcagcttca gccactccaa tacatcgtcg acatacgtaa aaatcaccgg caccaccaac
     4321 agactcagca gggttgaagt cagcaagcct cccatgacca ccacggccat cggctgcctg
     4381 aagctggggt cttcacccat gcccaaggca gtgggcaaca tgcctgcacc cattgcgatg
     4441 gtggtcatca gaatggggcg ggcacgcttg tgacaggcat ccaccaacgc gtcatatcga
     4501 cccaggccat aatcgcggcg agccatgatg gcgtactcca ccaacaggat ggagttcttg
     4561 gtcacgatgc ccatcaacat cagcaaaccg atgaccgatg gcagggaaaa gctgaaattg
     4621 cacaccaaca acgccaccag cgctccgccc aaggaaagcg ggagcgccga aagaatcgtg
     4681 gccggctgca ggaaatcgtg gaacagcaac accaggaccg agtagataca gaacacaccg
     4741 atggccatgg ccaggctgaa gctgccgaac aattcagtca tcagctgcaa ctcgccttgc
     4801 tccacccttt ttacctcagg tggaagattg cgcattgccg gtagctggct ggcctcggcc
     4861 atgacttcac ccaggttgcg tccgttaagt tcaatggaca gggtgatatt gcgcaagcga
     4921 tcgagccgac tgatctgcgc cggcccgctg cccatgctga tatctcccaa cgaggacaag
     4981 gtgacctgac catcgcggcc ggtcacccgt agctggttga tgctctgcag atcatcgcgc
     5041 agcagcgaat ccatccgcac ccgcacatcg acctggcgct gcgacaaatt gattttcccc
     5101 agctgcgagg aatattcgcc gtaggtcgcc atgcgcaacg tatcggcgat ctcctggctg
     5161 gtgatcccca gctccgccgc gcgggcgaag tccggccgca tctggatttc cgggcgttgc
     5221 agggcgctgc tggaggtgac gttgccgatc ccgtgcagct cgcgcagttg cggttccagc
     5281 gcacttgccg tgcgctccaa caggtcgccg tcgtcgctgg ccaggacgat attgagtttc
     5341 tcgccgctcc cgtcgccccc gacattgata cgcaccccgg gcagtgtacg cagcgcgtcg
     5401 cgcatctggg cttcgacttg cacctgtttg aggtcgcgct ggttccgatc caccagatcc
     5461 acggtcagga tggcatcgcc ggcgccggtt atatcggccg gcccggcccc cgagctgctg
     5521 gccgtcccca ccgaaatgaa cacatgcttg acctggggca tctcgctcag cctttcgctg
     5581 gcctgcaatg ccatcccggt ggtctgctcc agcgtcgtgc cgggaggcaa ttccagggtt
     5641 atccggctgc gaccgacgtc ctgggccggc aggaaactcg tgggcaacaa aggcaccagt
     5701 gcgagggctc cgatgaaaaa caggctggcc aggaccatcg tggttttgcg gcgggacagg
     5761 ctggcatgga tccagcccag gtagcgagtc atcaacgggc cgtcgtgtgc ggtatcggtc
     5821 ttggccttga ggaaataggc cgccatcatc ggggtcagta cccgggccac cagcaacgaa
     5881 aacagcaacg ccaccgaagc agtcacgccg aactggcgaa acagttttcc agccacgccg
     5941 cccatgaacg ccgtgggcag aaagaccgcg accagggtgg ccgtcgtggc gagcaccgcc
     6001 aggccgatct catccgctgc ttcggtagcc gcctgaagcg gcgtcttgcc catgcgcaag
     6061 tgccgggcaa tgttctcgat ttcgacgatg gcatcgtcca ccaacacacc gatgaccaac
     6121 gccagggcca gcagggaaac ggcgttgagc gtgaacccgg ccaggtacat cacgccaaag
     6181 gtggggatga tcgacaacgg cagcgccgtg gcgacgatca gcgtggcgcg ccagtcccgc
     6241 aggaaccacc agaccaccag caccgccagc agcatgcctt cgtacagcag gttcatcgag
     6301 tcgtggtaat tggcaagcac ggccttgacc gtatcgctgg cctcgtcgat acgcacattg
     6361 ggatgctgct gcacaaactc ggtcatgcgc ttgcgcacgt cgttggccac accgatatcg
     6421 gagaacccca gtgaccgcgt gatctggaag ccgatcaccg gcttgccatc gcgaaaagcc
     6481 cggctgctgc gctcggcgtg ggtgtcgcga atgtccgcca gttggctcaa tgccagcagg
     6541 cgcccatcgc cactgggaat atcgatggtg ccgaggacag ccggatcatc gatggctccc
     6601 agggtgcgca cggcctgctg gccgctgccc agattgccct gaccgccgga attgtctttc
     6661 tgcattgccc gcagttgcgc agcgacatcc gcgacacgga tgcccaaccc ggccatcaag
     6721 gccggatcga gattgacctg gacctcccga tcaaccccgc cgatacgtga gatcagcgcc
     6781 acgccgggca ccgacagcaa ctgtttgctc agctcgttat cgacaaacca cgacagtgct
     6841 tcctcatcca gggcatcaga agcgatgaca taggtcagca gcggcgatgc actggtggtc
     6901 aaccgcgaca ccgagggcgt atccaggctg gccggcagtt gcggcatggc gctgtcgacc
     6961 gcattgcgca cttcgttaag cgcctcgttg ccgtccttgt cgatgtcgaa actgacactg
     7021 atgctgacgg cgccgtcggt gatcaccgtc gtcacatgct tgagcaagcg cagggacgtg
     7081 agcttgtcct cgatcttgcg cgccacctcg gtttccagct gttcgggagc ggcaccctcc
     7141 agtgacgcgc tgatcaccac caccggcagg tccatgtccg ggaaatcctg gatggcaagc
     7201 ttgccgaaac ccagcaggcc gaagagcgtg agcagaatga acagcatcac cgccgggacc
     7261 ggataacgaa tcgacaacgc cgaaatattc atggctgggc gacctgggat tgtacgaggg
     7321 tcacactcgc accgtcattg aggaaggcgc caccggcgcg cacgatacgg gccccctgat
     7381 catccaggcc gctgaggatc tccaccgcct catgcatccg ccggcccacc accaccggtc
     7441 gctggaccac gtgcatgtcg tcgttgaggg taaacacata agagcggcca tcacgcagga
     7501 tcaccgccgt gtccggtacc gtgagcgctt cgcggggcgc cagttcgatc tggccactgg
     7561 catacatgcc ggcctgggcg gggctgccgg taggcaggga gatatacacc agggcccggc
     7621 tggtcttggt attcaatgtg ggcgacacca gccgcaccca cccttccagg ctctgcccgc
     7681 caggcaacgt cagtcgggca acctggccga cctggacctg ggccagctgg cgggcgtcca
     7741 gctcggcctg ccattcgatg cgaccgtcgc gcaccaggcg aaacagctcg tcgccggcgg
     7801 acagcacttt gccgagcagc gcggtgcgcg cggagatgat gccgtcatcc actgccacga
     7861 ttcgggtctg ccgaagcctg atccgggtgc tctgcaattc cgcccgggct ccggccaggt
     7921 cagcctcggc caacgccacc ttgatgcgat agtcttcgcg ctgctgctcc gacaaggcgc
     7981 cgccctggcc gacgacccgg gcacgacggt cgttggacct ggcctgttcc aggttggcca
     8041 ccgcttgggc gaccagagcc ttttgcttgc tttcctcggc gagcaccgtg tcagaggcca
     8101 gcgtcgccag cagttgcccc ttctttaccc gactgcccac gtcggcttcc aggctggcaa
     8161 tgcgcaggcc gctggtttcg gcattgatga ccgcttcctg ccagggtgca agtgcaccgt
     8221 tggcgaacaa cagttgcggc cagagctggg gccgggcctg gacaacctcc acgctcaggc
     8281 tgctgatact gggagcagcc gcgaccggct cagcgccacg acgaaacgtc atcaggatcg
     8341 ccacgaccgc gaccaccgcg atggtcagca ggatttttcg caacgtcggc ctcacacgcc
     8401 ctctccattc gatgtcgggt gccgagccag cggctggccg gtttgccatc cgccgcccaa
     8461 tgccttgtac agggcgatcc agtagcgaac ctgatcctgt tgcaaggtga tcaattcgat
     8521 ttccgccgtc agcgcctggc ggcgggcggt ttcccggtcc agcagactga cgctgccagc
     8581 ctgccaattg cggtcgatgg cctcgaacga ctcacgaaag ccagcggtgg aacgctcgac
     8641 atcggactcc cgtcgccgtg ccgcatcaag gcgcaccaag gcctgttcga cctccatgac
     8701 actggtgcgc agcgtctggc gataaaccgc gagggccgca tcgtaggaag ccttggcacc
     8761 gtccaccgcc gcgcgacgtt tgccgccgtc aaacagcggg accgacaaca ccgggcccag
     8821 tgaccaggag cgattgtgct gccctaccgt attgcctacc gaaaatgtgc cggacaggct
     8881 cagactcggc agccggtcgg cctgggccac gccgatctcg gcattcgccg ccgccagctc
     8941 ccgttcgctg gaggccacat ccgggcgctg gcgcagcatg tcggcaggaa tctgctgcac
     9001 gttgagtccg gcaggctccg gcagttgcgc cggggtcttg ccgagcacgc cgatcaatcg
     9061 ctcttcgtcg cccccggtca acgccaccag actcttgagc agaacctcgc attcactttg
     9121 ctgctggacc agagctgccg cgctgctggc ggcgctggca tcggccaggg cggcgtcggc
     9181 ggacgatgtg aagccggcac cgaacgactg gcgcgtgata cgcgccgtgt cctgctgcga
     9241 ttgggcctga tcccggtaag ccagcaccag tttctggcag ccacggtact gcacgtagta
     9301 gtcgcccacc tgtgccgcca gggaaactcg cgcgtcatgc cagtcatcca ctcgcgcctc
     9361 gacccgtgaa cgggccgctt cgttattgcg acgcagcttg ccgaacaggt cgatctccca
     9421 cgccgcgtcc agcgcagcgg aagaacctga gccgcccagg cgctggctcc ccgtctgttg
     9481 gccgccacgc cccttggata actggccgtc gatcctgggc atggcatcgg ctgcatcgct
     9541 gtctgcagtt gcccgtgcca atgcgatatt ggcccacgcc tgatccatcg acggactgtc
     9601 ggcttcggcc aggcgcagca gctcggccaa cgccgggtcg tcgaactgct gccaccagtc
     9661 ggccaaggcg gccaccgacg caccatgggg caagggagcc tgccacttgg ccgctaccgg
     9721 gacggccggt acccgatagt ccggccccaa cacgcaaccg ctcaggaccg cacacagtgt
     9781 cgccagcagt aggtttgccc ggggcttgaa gacatgcata ggtttttttg gaggcctggc
     9841 aaaggtgaac gaaccgttcg gagacgcggc agatttgatt cggttattta acctcggagc
     9901 cggttttgtg tctggcgtgg gaaacgggga caggtgccgg caagaaagtt cgcgataagt
     9961 gcggaggcct gctgaaatgg cccggacttg cgaataccac cccctgtggg agcgagcctg
    10021 ctcgcgatag cggcggtaca tgcaccctcg atgcgactgc cctaccgcta tcgcgagcag
    10081 gctcgctccc acagggtctt gcgcagaacc tacgggtgtc ctgcgcccct ccctttccat
    10141 agccaacgga tgatcgaaca tggaagcact cagttatctc gaaaatgtcg agtcgaatgc
    10201 gcgaacctat gcgcagaatg gaagcactca gttatctcga aaatgtcgag tcgaatgcgc
    10261 gaacctatgc gcagactttc cagcggctat ttgtcagcgg caaggggatg cggatcaagg
    10321 acgccagcgg ccaggagttt ctcgattgcc tttctaacgc cgggaccctg gccttgggac
    10381 acaatccgcc ggaagtccgg gatgcggtga tgacgtttct cgctggcgat catctgcagc
    10441 aggccctcga cctggcgaca ccggccaagc atgccttcgt ccaggagctg ttctccacgc
    10501 tgccggcgaa catgcgcgag accagcaaga tcctgttctg cgggcccagc ggctcggatg
    10561 cggtcgaggc cgccatcaag ctggcgcgcc actacacccg gcgctcgccg ctgatggctt
    10621 ttcacggtgg ctatcacgga atgaccgccg gggcgctgtc ggcgatgggt aagctatcgc
    10681 cgaagaccgg tgacggtctt atcgcccagg gcacgcactt cctgccgttc ccctatcgct
    10741 tccgttgccc cttcggcacc gatggcgaac acaccgatca gttgtccatc gactatatcc
    10801 gtaccgtgct gtcggaccct gagggaggcg ttgccaaacc ggcggcggtg atcgtcgagg
    10861 tggtgcaagg cgaaggcggt tgcatcccgg cctcggccaa ctggctgcgg gcactgcggg
    10921 aaatcaccct ggagcaggag atcctgttga tcgtcgacga agtccagacc ggcctgggtc
    10981 gcaccggcag tacctttgcc atcgaacacg cgggtatcgt gccggacatc ctggtgctgt
    11041 caaaagccat cggcggcggc tatcccctgg cggtcgttgt ctatgccgaa cacctggaca
    11101 cctgggggcc ggggatgcat gcagggactt tccgcggcaa ccaggtggcg atggtcgccg
    11161 gggctgcgac catgcgtcag atcaggaaag acaacctggt tgccaacgcc gcccggatgg
    11221 gcgaacgact ggaaaacggc ctgcaggata tcgcgcagcg gttttctttc atcggcgata
    11281 tccgcggacg cggcttgatg atcggggtgg aaatcaccca accgaccacc acccaacgcg
    11341 caggccaggc cgacggcgcc ctggcgcacg ccatcaagct caagtgcttc gacaatggcc
    11401 tgatgatgga gaccggcgga cgccacggcg cggtactcag gttcctgccg cccctgacca
    11461 tcaccgaggg tgaagtcgac atggtccttg accggtttga acagtcactc ggaaaaatcg
    11521 tcgaaacatg cccctatgcg gcacgcgaaa cagtctgaaa aaccaccctt tgcagcacgc
    11581 tagcacccgc ccccctttgt gggagcgggc ttgctcgcga aggcgtcggc atatccaaca
    11641 tcagtgcacg ctgacccacc gctatcgcga gcaggctcgc tcccagactt gatctgtgcc
    11701 gaccgcaata tccgcaacac cccattcccc tctgtgggag cgagcctgct cgcgatggcg
    11761 tcgggtcagt cagcatcgaa gttggatgca ccaccgctat cgcgagcagg ctcgctccca
    11821 cagaggacag tgatgctggc cccgaatacc tcatcaatca cgcgccaagg cattgatcgg
    11881 atcaagccgt gccgcattgc gtgcaggtac gaaaccgaac acgatgccta tgagtgtcga
    11941 acagacgacc gcggtgatga tcgatcccat cgagaacacc atttgccatt ccttgacgaa
    12001 gatcgaaaag acatagccga tgctgaacga caatccgatg ccaatcgtgc cccccagcag
    12061 gcagaccatc accgcctcca cgagaaactg ctggcgtata tcggactgac gcgcgcccac
    12121 tgccatgcgg atgccgattt cacgggttcg ttcggtcacc gaaaccagca tgatattcat
    12181 cacgccgatc cccccgacta ccagtgagat gaccgcgatg agcgagagca gcagtgccag
    12241 tgactgactg gtcttctgca ccgtctgcat cacgctgtcg aggttgtagg tgaagaagtc
    12301 cttgatgcca tgacgctgcg tcagcagctt gaccacgttg tcctccacca gtttgctcgg
    12361 ttgcccgtcc tttatccgca ctgtgatgct gtccaggaaa cgctggccca gcaagcgtcc
    12421 cgccgccgtt tcatagggca tccagatgtt caggttcttg ctggtattga acacgctctt
    12481 gcggtcctcg gtcacgccga tgacagtgca aggcaggttg tcgacaagaa tcaccttgcc
    12541 cagcgggtcc gtgtgcgaac cgaacagtcg ctggctggtg ttatggtcga tcaccaccac
    12601 ttgcgactgc cgccgggagt cgtccttgtt gaacgctacg cccgagccga tcttgatacc
    12661 gcgaacctgg aagtaactct cgctcacacc attgacggtc gcattgacgt cgatgttctg
    12721 gtaacgcaac agcaggttgc gccccaggtt cggggtggca ctgtcgatgt agtacaggtc
    12781 gctcagggcc gtgacgtcgg agagcaccaa cgtttcgatt gccgtcgagc ggctgtcgcc
    12841 ccagtcggcc ccgggcatga tctcgatggt attgctgccg atcgcttcga tgtctttcaa
    12901 gacatattgc ttgacccctt caccgatggc gacgatcgat accaccgaag tgatgccgat
    12961 gatgatgccc agcatcgtca gcagcgttcg catccggtgc gagatcagcg cgacccaggc
    13021 catgttgaac gcttcgctga acagcccgaa actggcgagc agtcggttcg acggcttgac
    13081 cttggccggt ggagtgccct gtggcggctg atcttccatt gatcgccgtg gattggccct
    13141 gtcgctgaca atctcgccgt cgcggatctc gatgatgcgt tgggcgtagg ctgcgacttt
    13201 ctcatcgtgg gtcacgatga tcaccgtgtg ccccgccgcg ttgagctcca gcaggatctt
    13261 catcacctct ttgccgctgg cggtgtccag cgcaccggtg ggttcgtcgg cgaggatgat
    13321 ctcgcctccg ttcatcaagg cccgggcaat actcacccgc tgttgctgcc cgccggagag
    13381 ctggctgggt cgattggcca ggtgcccggt cagccccagg cggcccagca actccccggc
    13441 acggttgtgc cgttgcgact cggcggcgcc ggcatagata gccggcatct cgacgttgtg
    13501 caaggcactc aagtggggca acaggtgata gcgctgaaaa atgaaaccaa agtgatcgcg
    13561 acgcagctcc gccaactcat ggtcgtccat cgagccggtt tcgcgcccat ccactttgta
    13621 gctgccggaa ctcggatgat cgaggcaacc gagcacattc atcagggtgg atttgccgga
    13681 gccggacgct cccgtgatcg ccacgatttc cccggcattg atcgtcaggt tgatgtcctt
    13741 gagcgcgatg aacgcctttt cgcccgcttg aaaactacgg gtgatccctt cgagttccaa
    13801 cagtggtcgc gtcatggtca ggctcctgcc acggctgggg tcggctcacc gatgacgacc
    13861 ttgtcacctt ctgccaggcc atccttgatt tcagccctga cgttgttgtt gatacccgtc
    13921 tggacgttgc gcggctgggc cttgccttcc gcgtccagta cacggaccac gtagctgcca
    13981 tcctggttct tcgcacccag ggccgcgacc ggaacggtca gcaccgcttt ggccttgtcc
    14041 aggacgatac ggacctgggc cgtcatcgag atacgcaggc gatgatcggg gttcggcacg
    14101 tcgaacaggc tgttgtagaa caccgcggtg ttctgcttgg gcgtcccggc gttctgcgtc
    14161 tccaggaagt tctgcggtgc cggctcagtg ccgcgcagcg tggcgtagta gcgcttttcc
    14221 gcctcaccga ggatggtgaa atacacttct tgcccgggca cgatgtgaat cacgtcggcc
    14281 tcggatacct gggccttgac ggtcatggtg tccaggtcag ccagtttcag cagcaccggc
    14341 gccagttgtt cggcgatcac ggtctggcct tcctgggtca cgatccccac cacatagccg
    14401 tcgataggcg cgacgatgtg ggtataggcc aggttgaccc gggccgtttc cacctggatc
    14461 tgcgcgtcct tgatctgtgc atcgagggac agcaggttgg cagcctccac cttgtagttc
    14521 gattcggcgg tctcgaattc ctgcttggaa atcgcgtcgt ccggttgcag caccttgtag
    14581 cgatcgtagg tggctttcgc gtccttgagt tgtgccgcgg tggcttgccg ctttgccttc
    14641 aggttttctt cgttgaccag ggcctggcgc aaggcgttct gcgccagcag cgggtcgatt
    14701 tccgccagcc actggccctt cttcaccttg tcgcccaact tgaccttgag cgacttcaat
    14761 tgcccggaca cctgggcacc gacatcaacc tgcttgacgc cctggagcgt cccggtggcc
    14821 agcaccgcgt tttcgatgtc tgtgcgctcg accgtagcgg tcaggtactc cggcggtttc
    14881 cccggcgact gagcgctgta gaaaaccagg ccggtcacta cgaccaggac aagcacgata
    14941 gcgattttgc gaaacttaga cttttccata aataaccatg agtgcgttga gttcaggccc
    15001 ggccaacgta gcgccgggtt ccatgggtgt gcccaaaggc agggcggcta gacgtagtca
    15061 ctggcctcct cctcatcgag catgggaagg ccgtcctgcc accaggcagc caggttatgt
    15121 acgtgaggcg ccttgagaat cgtgaagtgg ttgcccgggc cgtaccaaat gctcaggtcc
    15181 ggtacatgct tgcgccaccc ttcgatcatt tcctgttgct cgcgcttgtt gccggcggta
    15241 tccagggttg gatcattcgc cagcaccagc cgcaccggcc cggtgtattg atgttgcggt
    15301 tgataaaccg tacgcagggc cgtaccaaag gcccgcgccg gaccacgcat cgaatccacc
    15361 gccgaacgct gtggcaacat gccggcgcgg accatgccgg catgcagcag gcgcatctgc
    15421 gccgaatcgt cctgggcgcc gaacaccgtg gcatcgatcc ccagggattt acccgaggcc
    15481 agttgcatcg cctcgatcaa ccggttcaac actccagtcc cggtataagg cctgcccacc
    15541 acgccgttgc cgccgggcga ttcgctgtcg atcagcgtca acgaggctac tttgcgacca
    15601 cgggcgtgca gacgtgccgc catctcgaag acaatccagc caccgaagga atgccccagc
    15661 agatgcaccg gcccctccgg ttgcaccttg tcgatggctt cgaggtacgc ctgggcggcg
    15721 gtttccacca ggctgaaagg ctctgtgctg ccgtccagcc cccgatgttg caacccatgg
    15781 ataggccagt ccgggccaaa ggcgtcggtc aggccgatga aaccggtgac gctgtcgccg
    15841 gcccccggta cgcagaagat cggcgcccgg tcggcccgtc cgccctggat cgtcagcagc
    15901 ggctggtaac cgctcttcgg taagggtgcc ggacgcgatg cggcggtgtg aagctcggtg
    15961 ctgagggcct ggcccaacgc ctggacatgg ggcgcctgca tcatgctctg gtggttaccc
    16021 ggtaccttga cgcaatgcag ctgcgacgtg ggcaggacag cgtcccagcc cagataaccg
    16081 gagtgctcgg gagcgtcgtc ctggcgttct tcggccacca gcagatgcac gggtacggaa
    16141 atcggataca ccatgtaatg ggccaacgca tgaccgtggg ccacttcgcg atcgaggtac
    16201 tgccagagct gctccgcact gtagacggcc agctcggccg gcagtaccgc gtcgtcgcgg
    16261 caatgctgca ccaggccttc gaaatcgaat cgatccagtt gcccctgcag atcggccagt
    16321 ttcgccagga tcgctgctag tacctcttcg ccaggcaacg cagccctcca gaacacatcg
    16381 caacggtcca gcagatgcag cttgtgggct tcgtccaacg cccagcgcga ccgcccctga
    16441 tccaccagcc gaggcagata gctgtcgatg aggccgacga actcgacctc ctcgtccagg
    16501 ccgatcagct ggatcgcggt ctcgtaggcc agcacaccac cgaacgacca gccggccagg
    16561 cgataaggcc cttggggttg taccgaacga atgatcccca ccagccgcga ggccatgcat
    16621 tccattgtct gcaactgcgg ctcgccccac tcgacggcag gcaggccata caccgggata
    16681 tccgggtcga tgtgcttgcc cagcgtcggg aagtacaggt ccaggccact gaactcgtgc
    16741 accaggaaca gcggattctg ctgaccggtg gtgcgcacag gtacgatggc ctccttgacc
    16801 tgggcatcct cggtacgggt ctgcagcatc gatgccatcg acgcgacact ttcgtgctgg
    16861 aacagctcgg ccagcgagac ggtcaggttg gcctgtgcca acaatccgac cagccggatc
    16921 gccagcaatg aatgaccgcc cagttcaaag aagttgtcgt gacgaccgac ctgctccagc
    16981 ttcaggacgt cggcccacaa gcctgccagc atgacttcca ggtcgccttg cggcgcctcg
    17041 tagccctggc tcccataagc gtgcagttcc ggtaccggca gcgccccggt gttgaccttg
    17101 ccgttcagcg tcagcggcaa cgccgtcaat ttcacatagg cggccgggat catgtattcc
    17161 ggcagcacgg agcgcagttg ggcgcgcagt acatccgcat cgaggcctcc agcgttctcg
    17221 tgctcggtgt agtacgcgat caggcgcttg tcgcccggac tgtcttcacg cgcgaccacc
    17281 agggcttcgc gtaccccgtg gcactcgtgc aaacgggcct cgatctcacc gagctcaata
    17341 cggaaaccac gtattttgac ctgcccgtcg ttgcgatcca ggtattcgat ggtgccgtcg
    17401 ggcagccagc ggccaagatc gccactgcgg tacagacgcg cggtgcccga atcgctgaac
    17461 ggatcggcaa tgaagcgttc ctcggtcagg tccggccggt tcaggtaacc gagggccacc
    17521 ccgacaccac cgatatggat ttcccccgcg acacccacag gtaccggttg gcgcgcagca
    17581 tcgaggatat atacccgggt gttggcgata ggacggccga tcggaacact cgttgcgcca
    17641 tgcggcacgg cagtgaccac atgggtcgtc gcaaaggtgg tggtctcggt gggaccatag
    17701 caatgcacca gccgcagcga aggagcatgg gccaacagcc gccggaagga tgccggatca
    17761 ccgcgctcgc caccgcacaa caggatccgc aggcctgcca gggcatccgg gatcagtacc
    17821 aggtattgat tgaacatggc ggtggtgacg aacagtaccg agacctcggc atctgtcagc
    17881 gcttgggcga attgcgtcgg gctgagcaag gtttcgtgat cgatgatcac aacgcgcccg
    17941 ccattgagca atgcccccca cacctccatc gtactggcgt cgaacgccgg gttcgaggcg
    18001 aaagccacgt gatcctgtac accgaaatcc gcgtagccgt tattgatcgc caatcggcct
    18061 atggccaggt gcggcacgat cacccctttc gggtggcccg tggagccgga ggtgtacatg
    18121 atgtacgccg gtgtatcgct ggtttgaccg gggaataccg ccggccttgc agcctggatc
    18181 acctgcagcg tgtccaggtc caatcgcggc atgtcttccg gcaagcccct gtcactggtc
    18241 gtcagcacca gcactgcggc actgtcttgc aacatgaagc gctgccgctc ctcgggcgca
    18301 tggtgatcca gcggtacgta gacggcggcg cacttgagga tcgccagttc gctgatgacg
    18361 agctcaaacg aacggttcag catgatcgcg acccgcgacc ctggctggac gccccgttca
    18421 agcaagcaat gcgccaggtg attggcccgc tcgtgcagct cccggtaggt gagttgctgc
    18481 gccccatgct ggagtgcaat cccttcaggc cgggctttga cctgggcttc gaacaagccg
    18541 tggaccgtct cttcgcgggg atagaccgtg tcggttgcat tgaagtcgac cagcagttgc
    18601 cgacgttccg ccgccggcaa tatcgccagc tcgcgcaagg gtacctcggg cgtgtgctca
    18661 agcgcatcga ccaggctctc cagcgccgtg tgcatgtagc cgcagatgcg ttccgccccg
    18721 atgcgcgact ccgccagggc ggtcagcacg aaggcctcac cgagatcgtc gacgttcagc
    18781 gacagtggat agttgctcca ctcctcaccg ccgagcccct cgatcccgtt ccaggccgac
    18841 tgggcctcct gggtgacctg cgttgcagtg tgccggtaat tcagcagtgc actgaacaat
    18901 ggcgtcgacg tggcgacacc gctgcaacgc tgtgccagcg ccagcgacgc atgttcgtgt
    18961 cccagcagcg cggtgagacg cgcatgcgtc gtcttgacgc ctgcccgtgc cccgtcgacg
    19021 ccgacgtcaa cccgcagcgg caaggtgttg atgaacaacc ccagcgcccg atcggccccc
    19081 tcaccgccct gcatccggcc catcagcacg gtaccgaaca ccacgtcttc gcgcccggac
    19141 acagcgccta ccacccgcgc ccaggccaag tgatgcaggc tcgcggcgct gacgccaagc
    19201 agtcgcgatt gtgtccgcag acgacgattc aaactgtcgt ccacacccaa ccgggcctgt
    19261 tcgatgacat ggctgtcgcc ctgcacgtcc tgcaggccga atggcagggt cggctcctgg
    19321 atatcctgga gcatgtccct gaagaacgcc tcgtgggcgc tttgcgtcac gccaagccgc
    19381 gcctgggcca cgtagttgcg atacggcacg gcatcgccca actgggcctg ctgcccgagc
    19441 aagtacgctt gcatatcgtg ctgaatcacc tccagcgcgg tgtgatcgag tgcaatgtga
    19501 tggaacagca gtagcgcaac ccaacgctgg tgttcgtcgt cataggcaca ggcaagccgc
    19561 atcatgggtg cctggcgcac atcgagccga tagtgccgag ggtcgaaacg ctcacgaagc
    19621 tgcgcgccca cgtcctggcc cggctcgacc atacaggtct gcaccgccaa tggtgcttgg
    19681 cgcagcacca cctgcaccgg ctcgcgcaag ccctcccaaa gcacagccgt gcgcaggata
    19741 tcgtggcggt cgatcacgcc ttgcagggca ttgacgaagt catccagccg ggcacgatcc
    19801 ttgaagttga acatggcctg ctgcacatag agatcgccct gctgcgaagc caggtggtga
    19861 tacagaatcc cttcctgcaa cggcgccagg gcgtagatgt cctggacatt gctcatgccg
    19921 ccgggcacgc cggcgacgac ggcgtcgatt tcccgctggc tcagatcggc gagcggcaac
    19981 atctgcgggg tgatctgctc acagtccggc acgatgccgt tgtccggcac cacgatttcc
    20041 gtcgcgccgc ccacggccgc cgccaacgcg gccagggtcg gttggccgaa cagcacccgc
    20101 acatcggcgc tcaaaccgga ctggcgcatg cgttcgatca gcgtgaccgc caacaacgag
    20161 tgcccaccca actcgaagaa gtggtcatga cgccccaccc tctcaacctt gagcagctcg
    20221 gcccacagtt gtgccagcgt cgtttccacc gcgccctgtg gcgcttcgta ttcacgagta
    20281 attaccgagg cctggtccgg cgccggcagt gccttgcgat tcagcttgcc attcggcgtc
    20341 agcggcaatg catcaagccg cacataggcc gccggcacca tgtattccgg cagttgggct
    20401 tgcagctggg cacgcaggct ttcgatctcg atgttgaact cgtcaccgtg cacggtgaag
    20461 tacgccacca gacgcttggc ccccggcacg tcttcgcgag ccagcaccac ggcttccttg
    20521 atcgccgcgt gccgggcaag cttggcctcg atctcgccca gctcgatacg gaacccgcgg
    20581 atcttcacct gatcgtcgtt acggcccagg tagtcgatat tgccatccgc caggtaacgc
    20641 cccaggtcgc cggtgcggta catccgggca ttcggccgct cactgaacgg gtcgtcgagg
    20701 aaacgctccg ccgtcagttc cggacggtgc aggtaccccc gcgccacctg gacgccaccg
    20761 atgtagatct ccccggccac gcccataggc accggttgct ggtgggcgtc gagcagatag
    20821 atccgggtgt tggcgatcgg cttgccgatc ggcgtgctgt ccggtgtctc ggcgccggag
    20881 cagtcccagg ccgtcacgtc aacggccgct tcggtcgggc catacaggtt gtgcaaagac
    20941 gtccgtggca attgcgcctt gaagcgccgc accagatggc ccggcaaggc ttcgccactg
    21001 cacatcacct gacgcaaccc ctcgcactcg ccagcctcgc catgggccag gaacacatcc
    21061 agcatcgacg gtacgaagtg cagcgtggtg atgccttgag tctggatcac ttcgcgcagg
    21121 tacgccgggt cgcgatgtcc accgggacgc gccatcacca gccgggcgcc ggtgaacagc
    21181 ggccagaaga actcccacac agagacgtcg aagctgaacg gggtcttctg cagcaccgcg
    21241 tccgcggcgc tcagcgtgta ggcatcctgc atccacaaca ggcggttgac caccgcgcca
    21301 tgctcgttca tcacgccctt gggcaggccg gtggagccgg aggtgtagat cacgtaagcc
    21361 aggtgatcgg cccgcaggcc ctgcacctgt ggattgccgg ttggctgcgt ggcaaagtct
    21421 tcatcttcga gcacgatcac tctggcagcg gtcgcgggca ggttcatctg caaggcgcgc
    21481 tgggtgagta ctacggctgg ggcgctgctt tccagcatgt aggccaggcg atccccgg
//
