BGC0000332: cyanopeptolin biosynthetic gene cluster from Microcystis sp. NIVA-CYA 172/5
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 31,880 nt. (total: 31,880 nt).
This entry is originally from NCBI GenBank DQ075244.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000332
Short description cyanopeptolin biosynthetic gene cluster from Microcystis sp. NIVA-CYA 172/5
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: DQ075244.1
Compounds
  • cyanopeptolin
Species Microcystis sp. NIVA-CYA 172/5 [taxonomy]
References
Chemical products information
cyanopeptolin
Copy SMILES
C40H63N9O14S1
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAZ03548.1
  • mcnG
 85 - 1254 (-) McnG
copy AA seq
copy Nt seq
  • AAZ03549.1
  • mcnF
 1316 - 3385 (-) McnF
copy AA seq
copy Nt seq
  • AAZ03550.1
  • mcnA
 3953 - 7249 (+) McnA
copy AA seq
copy Nt seq
  • AAZ03551.1
  • mcnB
 7252 - 10569 (+) McnB
copy AA seq
copy Nt seq
  • AAZ03552.1
  • mcnC
 10566 - 24731 (+) McnC
copy AA seq
copy Nt seq
  • AAZ03553.1
  • mcnD
 24728 - 26605 (+) McnD
copy AA seq
copy Nt seq
  • AAZ03554.1
  • mcnE
 26602 - 30858 (+) McnE
copy AA seq
copy Nt seq
NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
mcnA
Module ?
Specificity: glutamine
Evidence for specificity:
  • Structure-based inference
mcnB
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
mcnC
Module ?
Specificity: isoleucine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: 3-amino-6-hydroxy-2-piperidone
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: phenylalanine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: 3-chlorotyrosine / tyrosine
Evidence for specificity:
  • Structure-based inference
mcnE
Module ?
Specificity: glutamine
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.