Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000352.1:
Cluster 1NRP126231

BGC0000352, fimsbactin biosynthetic gene cluster from Acinetobacter sp. ADP1. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: Fimsbactin A
SMILES string: Copy to clipboard
Molecular formula: C26H31N4O11
Exact molecular mass: 575.198384 Da ([M+H]+)
Molecular activity: Siderophore

Class-specific details

Biosynthetic class(es):
NRP
NRP siderophore (linear)
Thioesterase type:
None
Release / cyclization type:
Other

Nonribosomal peptide synthetases:
fbsE (ACIAD2773)
Module 1
A specificity: Unknown
Evidence for specificity: Structure-based inference
C domain subtype: Heterocyclization
Scaffold-modifying domain: Other
Module 2
A specificity: Serine
Evidence for specificity: Structure-based inference
C domain subtype: LCL
Module 3
A specificity: Serine
Evidence for specificity: Structure-based inference
C domain subtype: LCL

Gene cluster description

fimsbactin (BGC0000352). Gene Cluster 1. Biosynthetic class = NRP. GenBank CR543861. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Knock-out studies, Gene expression correlated with compound production, Sequence-based prediction
MIxS-compliance:Unknown
Contact for this cluster:Helge B. Bode (Molecular Biotechnology, Institute for Molecular Bioscience, Goethe University Frankfurt, 60438 Frankfurt/Main, Germany)

Literature references

1. Proschak A et al. (2013) Structure and biosynthesis of fimsbactins A-F, siderophores from Acinetobacter baumannii and Acinetobacter baylyi. Chembiochem 14(5):633-8. doi: 10.1002/cbic.201200764. Epub 2013 Mar