Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000353.1:
Cluster 1NRP128732

BGC0000353, FK506 biosynthetic gene cluster from Streptomyces sp. MA6548. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: FK506
PubChem ID: 6473866
SMILES string: Copy to clipboard
Molecular formula: C44H69NO12
Average molecular mass: 804.031 Da

Class-specific details

Biosynthetic class(es):

Gene cluster description

FK506 (BGC0000353). Gene Cluster 1. Biosynthetic class = NRP. GenBank AF082100. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Motamedi H, Shafiee A. (1998) The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506. Eur J Biochem 256(3):528-34.