LOCUS       BGC0000355             24812 bp    DNA     linear   CON 23-MAR-2015
DEFINITION  Aspergillus fumigatus Af293 chromosome 6, whole genome shotgun
            sequence.
ACCESSION   BGC0000355
VERSION     BGC0000355
KEYWORDS    .
SOURCE      Aspergillus fumigatus Af293
  ORGANISM  Aspergillus fumigatus Af293
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Fumigati.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 18:38:33
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 24812
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             join(1..154,205..605,673..863,925..1416,1482..1848)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169:sugar
                     transport protein (Score: 305.6; E-value: 9.3e-93)"
                     /gene_kind="transport"
                     /locus_tag="AFUA_6G12040"
                     /note="encoded by transcript AFUA_6G12040A; GO_component:
                     GO:0005624 - membrane fraction; GO_function: GO:0005352 -
                     alpha-glucoside:hydrogen symporter activity; GO_function:
                     GO:0005364 - maltose:hydrogen symporter activity;
                     GO_function: GO:0015574 - trehalose transporter activity;
                     GO_process: GO:0000017 - alpha-glucoside transport;
                     GO_process: GO:0015771 - trehalose transport"
                     /old_locus_tag="Afu6g12040"
                     /product="MFS transporter, putative"
                     /protein_id="EAL89045.1"
                     /transl_table=1
                     /translation="MPEDKVEAIEHVESSRHDATVNEKAIADFLNAEKEMTTWQAVRAH
                     RRLLLFAAYRVTHLAILPFVCASNYGYDTVSNGSSIAMPAFIMSFGAMNHATGSMYLPS
                     IWTSLWTSMTNLGQALGSLIAGFLAERIGRRWTAVSLAILSIVGTFILVFSSTRGMLLV
                     GKTMNGAVVGGLMAIGTTYAADVAPIKLRGALLQAIVFFGVAMQGVSLGIVRAFILDMR
                     PLAWKIVFGIQWAFATLVLIAAFLVPESPVFYVAHGKHDKAQSALRRLHGSSDQYLHIR
                     YGAIVHALDEERKQQSESVSWAELFKGCNLKRTITIGFIMFSTSAIGVPFLTQNIYFLI
                     TVGLNVTSVFDIGIGGFFLGCLFVMLGWLSNEGIGRRRLWLWGLIGNFLCMVTIGALGF
                     STTKASQLAIAVIMNVLISYGVYATVGVAWTICPEISSHRLRQYSQSVAFIVGAVGGWL
                     FNFITPYMYNVDSGNLGAKTGFVYAGLTVVVAVISWFLVPETAGLSVEDIDRAYEMGTA
                     PRHFKSAKATVSAESGH"
     protocluster    1..24812
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[3099:24812]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3100..24812
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..24812
                     /SMILES="NC(C)C(=O)NC([*])C(=O)NC([*])C(=O)NC(C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..24812
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000355"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..24812
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     mRNA            join(<1..154,205..605,673..863,925..1416,1482..>1848)
                     /locus_tag="AFUA_6G12040"
                     /note="transcript AFUA_6G12040A"
                     /old_locus_tag="Afu6g12040"
                     /product="MFS sugar permease, putative"
     gene            <1..>1848
                     /locus_tag="AFUA_6G12040"
                     /old_locus_tag="Afu6g12040"
     mRNA            join(<3100..3186,3619..>7014)
                     /locus_tag="AFUA_6G12050"
                     /note="transcript AFUA_6G12050A"
                     /old_locus_tag="Afu6g12050"
                     /product="nonribosomal peptide synthase, putative"
     gene            <3100..>7014
                     /locus_tag="AFUA_6G12050"
                     /old_locus_tag="Afu6g12050"
     CDS             join(3100..3186,3619..7014)
                     /EC_number="6.3.2.-"
                     /NRPS_PKS="Domain: AMP-binding (110-505). E-value: 3.6e-83.
                     Score: 271.2. Matches aSDomain:
                     nrpspksdomains_AFUA_6G12050_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (647-716). E-value: 1.2e-15. Score:
                     49.3. Matches aSDomain: nrpspksdomains_AFUA_6G12050_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (750-1025). E-value:
                     8.6e-25. Score: 79.2. Matches aSDomain:
                     nrpspksdomains_AFUA_6G12050_Condensation_DCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     269.3; E-value: 8.9e-82)"
                     /gene_kind="biosynthetic"
                     /locus_tag="AFUA_6G12050"
                     /note="encoded by transcript AFUA_6G12050A; similar to
                     nonribosomal peptide synthase (GI:32264582) [Alternaria
                     brassicae]; GO_function: GO:0003824 - catalytic activity;
                     GO_process: GO:0019184 - nonribosomal peptide biosynthetic
                     process; GO_process: GO:0043042 - amino acid adenylylation
                     by nonribosomal peptide synthase"
                     /old_locus_tag="Afu6g12050"
                     /product="nonribosomal peptide synthetase"
                     /protein_id="EAL89046.1"
                     /sec_met_domain="Condensation (E-value: 4.3e-27, bitscore:
                     83.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-89, bitscore:
                     288.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.8e-13, bitscore:
                     37.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MPDLIQTKSVVLGYGVKMVLAPAKAARSLLIREEAVWRFSLPRVL
                     STPTTMLETTEPIAHASELDKPSIVVTNTEVDSEDNTSSVLGRYIPQKCLQNARLAAVN
                     SCVNEIFEARFRERPDAPAVCAWDGSYTYRELNDRSSALAHKLRRRGVQAEVLVALLFE
                     KSKFSVVAMHAVIKAGGAFQLWDPSLPVARLGGMFAESKAHLVLASAANARLAAEISEN
                     VMVVDESLVPPWESAPLNPGTQPENALYCVFTSGSTGKPKGFLMDHRAFCTCALGVGEL
                     LGLNGASRLIQFSANSFDLATFDHILPFLCGACLCIPSEEERKGDLTRAFNRYRATHAV
                     LTPTVSRLLEPEKLTTLQVLLLAGEAPSREDIRRWASTVGLLNGYSPAEAGCITIVNPS
                     LQESHPSKIGFPVSVVPWVVDPDDCNRLVPAGEVGELVLQGHTLARGYFGRPDQSKAAF
                     IPTPAWVRQFGYETYGRLYRTGDLVRFDAEDESLVYIGRKDSQVKIRGQRLELGEVEHA
                     LQQFFPRPQIVVVELLTAEDREPALVGFVYQPGSSQHMPAPPQHQDNSLFLVADDQFCA
                     DAQKALASLRDILPPYMIPSDLLRISHLPMVPSGKTDRRLIRMRAVDLAPEERRKYSSV
                     LGQSRDQPVTQLEESLLGLWATCLKLPPSQIGVLDNFFHLGGGSLEAIHLAAEARNMGF
                     AELSSAAVFQCPTIREMAGMLDGVTASVQEQDPRGCTSFQLESSLVAELLRKSQCTLED
                     LQEGFLPLTPFQEKTAKMKPMHLLLDIPGIDHSRLEAAWALVLEKHISFRSIYVEHQGR
                     VYQAFLRQPDTVSIPIRWCDEPVHECAARFCEQDVDLILDGRPWWSMTRINNKIDSVLV
                     LRLTHAQWDALTLDVLFKDFMAAYESRELSRRDLEFPAYMRFRLRHNASPATVRFWSTF
                     LHGSRLTQPLLLDGAAEVDPGNEAMVFVSQQIPMLTPPHGITLGSVFRAAWAFVLARYT
                     GQEDVVFGEFVEGRSLLVKSVEKVTGCAAAETPMRIVVSPTASVRDLLKHSQEQYVARI
                     PYETCELEDIVPSSTSWPTDTTFNHILVIQHEPVLPPVALDGRPCPHRWAFHGRLEDVY
                     VQMVFGPDTLHVGMSGPEIRLSRTIATQLVEKLASTITQFNDRPEALLSEITV"
     aSDomain        3862..5046
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_6G12050_AMP-binding.1"
                     /evalue="3.60E-83"
                     /label="AFUA_6G12050_AMP-binding.1"
                     /locus_tag="AFUA_6G12050"
                     /protein_end="505"
                     /protein_start="110"
                     /score="271.2"
                     /specificity="consensus: ala"
                     /tool="antismash"
                     /translation="FEARFRERPDAPAVCAWDGSYTYRELNDRSSALAHKLRRRGVQAE
                     VLVALLFEKSKFSVVAMHAVIKAGGAFQLWDPSLPVARLGGMFAESKAHLVLASAANAR
                     LAAEISENVMVVDESLVPPWESAPLNPGTQPENALYCVFTSGSTGKPKGFLMDHRAFCT
                     CALGVGELLGLNGASRLIQFSANSFDLATFDHILPFLCGACLCIPSEEERKGDLTRAFN
                     RYRATHAVLTPTVSRLLEPEKLTTLQVLLLAGEAPSREDIRRWASTVGLLNGYSPAEAG
                     CITIVNPSLQESHPSKIGFPVSVVPWVVDPDDCNRLVPAGEVGELVLQGHTLARGYFGR
                     PDQSKAAFIPTPAWVRQFGYETYGRLYRTGDLVRFDAEDESLVYIGRKDSQVKIR"
     aSModule        3862..5679
                     /complete
                     /domains="nrpspksdomains_AFUA_6G12050_AMP-binding.1"
                     /domains="nrpspksdomains_AFUA_6G12050_PCP.1"
                     /locus_tags="AFUA_6G12050"
                     /monomer_pairings="ala -> ala"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       4279..4335
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12050_0001"
                     /evalue="1.30E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="AFUA_6G12050"
                     /protein_end="268"
                     /protein_start="249"
                     /score="23.9"
                     /tool="antismash"
                     /translation="YCVFTSGSTGKPKGFLMDH"
     CDS_motif       4816..4905
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12050_0002"
                     /evalue="7.20E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="AFUA_6G12050"
                     /protein_end="458"
                     /protein_start="428"
                     /score="37.5"
                     /tool="antismash"
                     /translation="PAGEVGELVLQGHTLARGYFGRPDQSKAAF"
     CDS_motif       5011..5076
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12050_0003"
                     /evalue="1.50E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="AFUA_6G12050"
                     /protein_end="515"
                     /protein_start="493"
                     /score="36.3"
                     /tool="antismash"
                     /translation="YIGRKDSQVKIRGQRLELGEVE"
     aSDomain        5473..5679
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_6G12050_PCP.1"
                     /evalue="1.20E-15"
                     /label="AFUA_6G12050_PCP.1"
                     /locus_tag="AFUA_6G12050"
                     /protein_end="716"
                     /protein_start="647"
                     /score="49.3"
                     /tool="antismash"
                     /translation="EESLLGLWATCLKLPPSQIGVLDNFFHLGGGSLEAIHLAAEARNM
                     GFAELSSAAVFQCPTIREMAGMLD"
     aSDomain        5782..6606
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_6G12050_Condensation_DCL.1"
                     /domain_subtype="Condensation_DCL"
                     /evalue="8.60E-25"
                     /label="AFUA_6G12050_Condensation_DCL.1"
                     /locus_tag="AFUA_6G12050"
                     /protein_end="1025"
                     /protein_start="750"
                     /score="79.2"
                     /tool="antismash"
                     /translation="LEDLQEGFLPLTPFQEKTAKMKPMHLLLDIPGIDHSRLEAAWALV
                     LEKHISFRSIYVEHQGRVYQAFLRQPDTVSIPIRWCDEPVHECAARFCEQDVDLILDGR
                     PWWSMTRINNKIDSVLVLRLTHAQWDALTLDVLFKDFMAAYESRELSRRDLEFPAYMRF
                     RLRHNASPATVRFWSTFLHGSRLTQPLLLDGAAEVDPGNEAMVFVSQQIPMLTPPHGIT
                     LGSVFRAAWAFVLARYTGQEDVVFGEFVEGRSLLVKSVEKVTGCAAAETPMRI"
     CDS_motif       5878..5952
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12050_0004"
                     /evalue="1.20E-05"
                     /label="C2_DCL_024-062"
                     /locus_tag="AFUA_6G12050"
                     /protein_end="807"
                     /protein_start="782"
                     /score="17.6"
                     /tool="antismash"
                     /translation="IDHSRLEAAWALVLEKHISFRSIYV"
     mRNA            complement(join(<7415..7735,7757..8086,8176..>8781))
                     /locus_tag="AFUA_6G12060"
                     /note="transcript AFUA_6G12060A"
                     /old_locus_tag="Afu6g12060"
                     /product="MAK1-like monooxygenase, putative"
     gene            complement(<7415..>8781)
                     /locus_tag="AFUA_6G12060"
                     /old_locus_tag="Afu6g12060"
     CDS             complement(join(7415..7735,7757..8086,8176..8781))
                     /EC_number="1.14.13.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087:hypothetical
                     protein (Score: 201.6; E-value: 3.9e-61)"
                     /gene_kind="other"
                     /locus_tag="AFUA_6G12060"
                     /note="encoded by transcript AFUA_6G12060A; similar to
                     PIR:S70702: maackiain detoxification protein 1 [Nectria
                     haematococca] similar to Salicylate hydroxylase (EC
                     1.14.13.1) (Salicylate 1-monooxygenase).
                     (Swiss-Prot:P23262) [Pseudomonas putida;]; GO_function:
                     GO:0004497 - monooxygenase activity; GO_process: GO:0006725
                     - aromatic compound metabolic process"
                     /old_locus_tag="Afu6g12060"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="EAL89047.1"
                     /transl_table=1
                     /translation="MKLPAAAGDAIVIGPNAVRLIKSWGEQLCEEIEPHLSNATHAEML
                     DHHDRFIVRHELAGRGKGWFTNRGRLISILYEHARKLGIDIRLGSRVTKYWEEDGRAGV
                     IVNDRERLAADCVICADGVHSAARAWLTGQVDTQQHSGWANFRAHMTTEQLAKDPEASW
                     VLQGTREKDRVYVWFGDGINLAIMTMKRGQELAWALMHTDKFNAHESWAGGRASIDDAL
                     ATLSPWPGRLRPSSVIRHTLPEKLVDHALIYRPPLDTWVSAGGRVMLIGDAAHPYFPVV
                     GQGGSQAIEDGVVVATALELAGKENVPLALRIRATLTEENNVLMEAGNSRYPRATVIQL
                     GSSTLQEHLFWPDWEAVAKDPSVFAFPNPEWILGHDCREYTHQVFDTVVRAVRGEGEYI
                     PRNIPADGAYRVEDTYSPE"
     mRNA            join(<9610..9870,9921..10149,10234..10622,10694..11055,
                     11181..>11433)
                     /locus_tag="AFUA_6G12070"
                     /note="transcript AFUA_6G12070A"
                     /old_locus_tag="Afu6g12070"
                     /product="FAD binding domain protein"
     gene            <9610..>11433
                     /locus_tag="AFUA_6G12070"
                     /old_locus_tag="Afu6g12070"
     CDS             join(9610..9870,9921..10149,10234..10622,10694..11055,
                     11181..11433)
                     /EC_number="1.5.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 312.4;
                     E-value: 1.3e-94)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_6G12070"
                     /note="encoded by transcript AFUA_6G12070A; similar to
                     GB:BAC61978.1: putative oxidoreductase, oxygen dependent,
                     FAD-dependent protein [Vibrio parahaemolyticus];
                     GO_function: GO:0050660 - FAD binding"
                     /old_locus_tag="Afu6g12070"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="EAL89048.1"
                     /transl_table=1
                     /translation="MQYIPFLISGLVPVALSKSLFEATSNTRIDGNDIAAIFGPVLTPE
                     AHIFLPSDGDYDDNVMARWSTFNDPSYVATVKPATETDVQAIREYQVSTAASHNITFFA
                     TGGGHGVKLNFGNVQNAINIELSLLDFIDLDLDNEVVTIGPGVENAQLYDLLSSVGKET
                     ALTGERCVNTIGPTLGGGLGPLYGIRGPQVDSLVSARLVTASGDVITVSRSENRDLFWA
                     IRGAGANFGIVTSATYRIYDQTNGGMAVSAQFAFAPAVNRSVFDLMESMNDEYPPGMSG
                     GMILSYNHTTNEPSVQWNLLFMGSNEDAQPWLDKIQALGPIDSSIRNVPWHRRDEPEVP
                     YCERGQHYILYNLNLRRTDAATLQSYFDSFVDFSSKNPWFDCDLMYERQATDAALAVPL
                     SERGVGPWRDSKINANFLVVTPSEEYDEAADAFVRPFMDRFQAVMGFDTLHVYVNEALG
                     DEGPASWYGEENLPRLVALKQQWDPENKFGAGAPIPLSL"
     mRNA            complement(join(<12823..16290,16346..24196,24264..>24812))
                     /locus_tag="AFUA_6G12080"
                     /note="transcript AFUA_6G12080A"
                     /old_locus_tag="Afu6g12080"
                     /product="nonribosomal peptide synthase, putative"
     gene            complement(<12823..>24812)
                     /locus_tag="AFUA_6G12080"
                     /old_locus_tag="Afu6g12080"
     CDS             complement(join(12823..16290,16346..24196,24264..24812))
                     /EC_number="6.3.2.-"
                     /NRPS_PKS="Domain: AMP-binding (274-668). E-value: 2.3e-81.
                     Score: 265.3. Matches aSDomain:
                     nrpspksdomains_AFUA_6G12080_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (808-874). E-value: 3.6e-14. Score:
                     44.6. Matches aSDomain: nrpspksdomains_AFUA_6G12080_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (915-1187). E-value:
                     8.1e-44. Score: 141.7. Matches aSDomain:
                     nrpspksdomains_AFUA_6G12080_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1355-1750). E-value:
                     1.6e-93. Score: 305.4. Matches aSDomain:
                     nrpspksdomains_AFUA_6G12080_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1885-1946). E-value: 1.1e-13.
                     Score: 43.0. Matches aSDomain:
                     nrpspksdomains_AFUA_6G12080_PCP.2"
                     /NRPS_PKS="Domain: Epimerization (1970-2259). E-value:
                     1.2e-37. Score: 120.8. Matches aSDomain:
                     nrpspksdomains_AFUA_6G12080_Epimerization.1"
                     /NRPS_PKS="Domain: Condensation_DCL (2437-2724). E-value:
                     3.6e-37. Score: 119.9. Matches aSDomain:
                     nrpspksdomains_AFUA_6G12080_Condensation_DCL.2"
                     /NRPS_PKS="Domain: AMP-binding (2886-3283). E-value:
                     1.7e-84. Score: 275.6. Matches aSDomain:
                     nrpspksdomains_AFUA_6G12080_AMP-binding.3"
                     /NRPS_PKS="Domain: PCP (3427-3493). E-value: 2.8e-18.
                     Score: 57.8. Matches aSDomain:
                     nrpspksdomains_AFUA_6G12080_PCP.3"
                     /NRPS_PKS="Domain: Condensation_DCL (3557-3806). E-value:
                     1.3e-36. Score: 118.1. Matches aSDomain:
                     nrpspksdomains_AFUA_6G12080_Condensation_DCL.3"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     271.5; E-value: 1.8e-82)"
                     /gene_kind="biosynthetic"
                     /locus_tag="AFUA_6G12080"
                     /note="encoded by transcript AFUA_6G12080A; similar to
                     nonribosomal peptide synthase (GI:32264582) [Alternaria
                     brassicae] PMID: 14727058; GO_function: GO:0003824 -
                     catalytic activity; GO_process: GO:0019184 - nonribosomal
                     peptide biosynthetic process; GO_process: GO:0043042 -
                     amino acid adenylylation by nonribosomal peptide synthase"
                     /old_locus_tag="Afu6g12080"
                     /product="nonribosomal peptide synthetase"
                     /protein_id="EAL89049.1"
                     /sec_met_domain="Condensation (E-value: 2e-42, bitscore:
                     133.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 6.5e-103, bitscore:
                     332.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.5e-14, bitscore:
                     42.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MERLEAKNQTTKHGERMAPQRYSVLRDEKCLFPVRNDGKLLVDEW
                     RVTELAISSGEKGLKLCRTTCPTAGADPRYLAAAAWALLLWRFAEVDTVQIGLQDIPPG
                     ANEDILEAGLKRGMKVLAASRRQVQLLNELWQGDTWSISDADPTCYSYFDTGIVICRGN
                     SQDCLAKCRSPNQLRKANGEACNVLLVLELDLDSNWRKCFLAYKTTVLTDIQATHLKSS
                     FEEVVELARAGRGIPLSEICLVSRRQLDQIGKWNERALVQPKFKAMHQVVHDRATDRRH
                     HPAVIAADRALSYSELETLSLKVAYRLRGSGVQPGDLIPVCFCKSSWAIVAMLAINKLG
                     AAFVPLDPSQPVNRLKSITRQLDATLAVTSPENQSLVEDLVTTTVVVSETTVSELVDVH
                     NEIVLPACDPGAPAYCLFTSGSTGKPKGCVVDHAALASVATHSHALHLGPTSRVLQFAS
                     FTFGVSLIEVWCTLAAGGTVCLPSDSDRVSRLADAIRSMGVDWCILTPTVLATLEPEAV
                     PNLRTILVAGEPLKKAQFSLWAERARLFQAYGFTEWAGICCVSPQIRSIGDVGIIGTPA
                     NARCWLVEPGNPNQLAPIGAVAELAVEGPSLAQGYLHDPEKTAATLIPPPRWRAQYGHA
                     DGKRIYTTGDLVYYDSNGMLRYVSRKDRQVKIRGQRIDLAEPEYHIAQACCTIRNVVLD
                     AIVPADSNGDAILVAFVLPSRDESSSNGGHDSPLFAVPDDHFTSSVRQLTSFLEDKLPD
                     YMVPRLFLQLKETPVTITGKIARQKLREAAEALRHDELVALAGLETRVLPPNTHKETLI
                     HQLVVELLHLPPEMVGMNHNFFSLGGDSVSVMKLVSRAKRVGLSFTVKDVFRSPQLGDL
                     ARLTDVVNSGAAQHMPPFSLLDRGAQPGLLSMAAKICQVESSMIQDIYPCTPLQEGMMT
                     LSAAKAGSYIARFVYRLEEHVDSPRFRRAWEMTVEATPILRTRIISASDGRLYQVVIQE
                     KFRWDDDGQPSGECVQNGQDRHMLLGEPLTHAALVRDRNQDGSLSTVFVLTMHHSVCDR
                     WSVGLIMDSVETAYTGQTLTTNSMGPFLQYIQQLQGGDAFWRSQFVGVKAEVFPSLPSP
                     EYTPTPTETIDLSVELRDAVPGGHTIANAIRLAWALVISHYTSCSDVVFGVTISGRAVP
                     VPDIERIIGPIIATVPLRVRLKESSTVLEALKAIQDQSMEMIPFEQLGLRQIRKLSPEA
                     EEACNFQSQLVVQPAWGDENRSLFATCEAGAAAEGGFAAYALSMICQLVGSSQIDVRTE
                     FDPKVIQAPIMQRIVHHFVYTLQYLLAHPDARVAEIPVVSPGEKQLLRQWNGIVPPASH
                     QCVHEIIQQRQIERPTSTAVWAWDGQLTYAELGELSDRLAEYLATKGVQPEVIVPVCLE
                     KSYWTTVAMLGISKAGGAFALLDPSQPEQRLQSICHQLNSAVILTSEKNRDLAGKLASH
                     PIVLSLQSSRRWGHGPAKQAPATARPDHTLYVAFTSGSTGTPKGVVIEHRSFCTSALAL
                     NRITGVNSESRMLQFAGYSFDGSIMEMLSALMAGACVCVPSEFQRRNELVAAAAKFELT
                     HAHLTPSVARHLLRGNPEFTKTLVSVGEPMTASDVADWASNGQCKVMNGYGPAECAVST
                     TIQAAVTSASDPKNIGFPVAGVCWVVHPENHDILLPPGAVGELLIEGPTLARGYLNEPD
                     KTAAAFIPLPAWIKDIRPEQPHGRLYKSGDLVRYNADGSFQYIGRRDSQIKLRGQRIEL
                     DEVEKHVYQCWPGVIAVVAVEMVSFTPATQTLVAFVVVEEHVDTTGDILAAPTQEFTGQ
                     VAVAQARLREAIPAFMVPEIFIPLLVLPQSASGKTDRRRLRSIATACTREKLAAYGAVG
                     TGTKREPTSVAEREMQAIWAQALNLPLAEIGMDDSFYQLGGDSITAMQVVAHARSKGLA
                     VTMDSILRLKSISKIMSHESSLSPAIVHIDEEEDVWFALSPIQQMFFDRQPSGWDRFSQ
                     VFLLRVSQPVTASQLQMALHTLVSKHPMLRARFAKQHDGSWRQVITSKIQESYRCRSHR
                     LNRRSSVDGVVSSGACSLSIQKGPLIAVDLMSREDGAQYLSIVIHHLVVDLVSWRIILA
                     DLEAMLRGENPMANHSTPFQTWCRLQAEYARQYLSPQHAFPTDLPDHYHQDPSVFWGLA
                     GQPNLVRDSRRQVFTLDEHTTRQLLGAANAAFATRTDEVLHAVLLYSFLKVFPHRIAPL
                     TFSEGHGREPWDSAIDLSQTVGWFTTMWPVVAELQQNHSFLEVVCRVKDARRAVPCNGW
                     AYFVSRYLNPSGRQAFQQFHPVELVFNYAGEYQQFNQAGAFFIPDMPEYQGSLDAGEQI
                     QRFGIFEVFASVVRGCLQFQFMYNRYMKHQLEIQKWIESCRQTLIEGCSTLIAAKPSRT
                     LSDFPLLPLTYSTLRELLDVTLPTAGVSVENVEDIYPCSPSQRGMLIAQAKAAHNYNAS
                     VTWSIRSRIDSRPNVARLKAAWCEVVKRHAILRTVFVESPWPESYMDQVVLQNVSPEFV
                     FCRGSDSLPQSISSPGQTRWSKGQCQHIMRVWERDNGDILCRLDLSHAIMDRTTLAIIQ
                     KDLSLAYDERLLPGRAPLYRDYISYIYQQDSESARQYWQGYLEGVEPCEFPTLNPVDPS
                     ITKEWGNLYRTLEDRRRLEEFCRTHSVTPWNVAGLAWAMVLRSFTRTDSVCFGYVKSGR
                     DLPIDGIAGTAGPVFNPLPCRVHLTERLTVRETIGRLQEEYLQSLAHQSFPLSDIHRLA
                     GVTSGVLFNTSVAVQTEVASEAEEAKRSLEFTTVAMEDGTEDDMVITLVPRGGELVLHL
                     RHRSRTLTTDQASTVLATFEKALCSILANAEAPMTSIDVFSDHDKAILWSRNRRVPDAV
                     ESCVHELIQKHCVERPHSPAVNAWDGAFTYGQLDELSSRLAVYLAAQGVGPNVVVPLCF
                     EKTRWTPIAMMGVMKAGGAFLLLDPSYPLQRLKDICADIDCRLVVSSTTHEAMSRELAS
                     TVVVVGEDRHHWQLENTSHTITMPKVRPADALYVVFTSGSTGKPKGVVIEHRSYCSGAL
                     DHIRSYNLTPQSRVLQFSSYAFDISIVEQLSVLIAGGCICVISESQRKNSLGEAATALQ
                     ANHAMLIPSVARLVRHEDLSTITSLSLAGECMQETDVSYWAQHVRLMNGYGPAECSALS
                     LVQPCVLPHSDPHDIGYPVGSVAWVVDPHDHHKLVPNGAVGELLIEGPIVGRGYINNAE
                     KTAEVFIEPPTWLRTLRGHCTSRLYKTGDLVRANPSGSLSILGRKDRQVKLRGQRLELG
                     EVEANVQHCFPGALDVVADLLPSSRGGKPQLVAMVFQNAERAARIAPESDSKLIAEPSV
                     DFMQSATTAETRLRQTVPNFMVPSMFLPLAQIPRTHSDKVDRNSLLKAVAAMSSIELQA
                     YKASVDAGHCSTRAPSTEEEKKLAEIWADVLKVPVEHIGADDNFLLSGGDSIDAMKAAA
                     FCRAAGMALSVADIFAHPVLSDLAKVAVPKSLNGSSTSHQPFSLSPVDSPKDLHMSLME
                     QGLVPPGSALADLLPGTQAQQFFIERGTFHSYNFSIRGPLDRCRLQKTCTAILSRHSIL
                     RTKFLQYEGRLIQIVLDNLETPFTHYTTDGDLLEFCKSLWERDLAALDGLGRLPCKFTL
                     VSRSEQEHVFTIQISHAQWDGVSIPRLFSDIAAIYNQIPLPSTTHFADYVYHRSSRDER
                     PAFDFWKKYLRGSSMPVPFPATNCQDREHKTQWTFQGIKNPRLPAGITMASLVKAACGF
                     HLCQLLSQNDVVFGHTVNGRNLALDNVEALLGCCLNFIPLRVMLQPSWTVLDLLAHVQE
                     QYTRALPHEHLELRDIFRHSTPWPADTQLSFIVQHQNIELHHNIALDGLQVQYSKFAQF
                     DPLTEVWIFSEPHPDRLEIQVCANTRVLSEDQARALCRRLCDLIEFFSASPDCPLSKVV
                     DHMDRPGLLAEEKVLN"
     aSDomain        complement(13273..14019)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_6G12080_Condensation_DCL.3"
                     /domain_subtype="Condensation_DCL"
                     /evalue="1.30E-36"
                     /label="AFUA_6G12080_Condensation_DCL.3"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="3806"
                     /protein_start="3557"
                     /score="118.1"
                     /tool="antismash"
                     /translation="YNFSIRGPLDRCRLQKTCTAILSRHSILRTKFLQYEGRLIQIVLD
                     NLETPFTHYTTDGDLLEFCKSLWERDLAALDGLGRLPCKFTLVSRSEQEHVFTIQISHA
                     QWDGVSIPRLFSDIAAIYNQIPLPSTTHFADYVYHRSSRDERPAFDFWKKYLRGSSMPV
                     PFPATNCQDREHKTQWTFQGIKNPRLPAGITMASLVKAACGFHLCQLLSQNDVVFGHTV
                     NGRNLALDNVEALLGCCLNFIPLRVML"
     CDS_motif       complement(13282..13377)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0032"
                     /evalue="1.10E-09"
                     /label="C5_DCL_263-294"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="3803"
                     /protein_start="3771"
                     /score="30.7"
                     /tool="antismash"
                     /translation="DVVFGHTVNGRNLALDNVEALLGCCLNFIPLR"
     CDS_motif       complement(13654..13704)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0031"
                     /evalue="4.20E-02"
                     /label="C3_LCL_132-143"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="3679"
                     /protein_start="3662"
                     /score="6.7"
                     /tool="antismash"
                     /translation="WDGVSIPRLFSDIAAIY"
     CDS_motif       complement(13918..14010)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0030"
                     /evalue="8.40E-07"
                     /label="C2_DCL_024-062"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="3591"
                     /protein_start="3560"
                     /score="21.3"
                     /tool="antismash"
                     /translation="SIRGPLDRCRLQKTCTAILSRHSILRTKFLQ"
     aSDomain        complement(14212..14409)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_6G12080_PCP.3"
                     /evalue="2.80E-18"
                     /label="AFUA_6G12080_PCP.3"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="3493"
                     /protein_start="3427"
                     /score="57.8"
                     /tool="antismash"
                     /translation="EKKLAEIWADVLKVPVEHIGADDNFLLSGGDSIDAMKAAAFCRAA
                     GMALSVADIFAHPVLSDLAKV"
     aSModule        14212..17434
                     /complete
                     /domains="nrpspksdomains_AFUA_6G12080_Condensation_DCL.2"
                     /domains="nrpspksdomains_AFUA_6G12080_AMP-binding.3"
                     /domains="nrpspksdomains_AFUA_6G12080_PCP.3"
                     /locus_tags="AFUA_6G12080"
                     /monomer_pairings="ala -> ala"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(14311..14340)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0029"
                     /evalue="1.90E+01"
                     /label="PCP_mE"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="3460"
                     /protein_start="3450"
                     /score="-0.0"
                     /tool="antismash"
                     /translation="NFLLSGGDSI"
     CDS_motif       complement(14812..14874)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0028"
                     /evalue="5.80E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="3293"
                     /protein_start="3272"
                     /score="31.3"
                     /tool="antismash"
                     /translation="LGRKDRQVKLRGQRLELGEVE"
     aSDomain        complement(14842..16032)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_6G12080_AMP-binding.3"
                     /evalue="1.70E-84"
                     /label="AFUA_6G12080_AMP-binding.3"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="3283"
                     /protein_start="2886"
                     /score="275.6"
                     /specificity="consensus: ala"
                     /tool="antismash"
                     /translation="KHCVERPHSPAVNAWDGAFTYGQLDELSSRLAVYLAAQGVGPNVV
                     VPLCFEKTRWTPIAMMGVMKAGGAFLLLDPSYPLQRLKDICADIDCRLVVSSTTHEAMS
                     RELASTVVVVGEDRHHWQLENTSHTITMPKVRPADALYVVFTSGSTGKPKGVVIEHRSY
                     CSGALDHIRSYNLTPQSRVLQFSSYAFDISIVEQLSVLIAGGCICVISESQRKNSLGEA
                     ATALQANHAMLIPSVARLVRHEDLSTITSLSLAGECMQETDVSYWAQHVRLMNGYGPAE
                     CSALSLVQPCVLPHSDPHDIGYPVGSVAWVVDPHDHHKLVPNGAVGELLIEGPIVGRGY
                     INNAEKTAEVFIEPPTWLRTLRGHCTSRLYKTGDLVRANPSGSLSILGRKDRQVKLR"
     CDS_motif       complement(14980..15069)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0027"
                     /evalue="1.60E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="3237"
                     /protein_start="3207"
                     /score="42.8"
                     /tool="antismash"
                     /translation="PNGAVGELLIEGPIVGRGYINNAEKTAEVF"
     CDS_motif       complement(15184..15204)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0026"
                     /evalue="2.90E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="3169"
                     /protein_start="3162"
                     /score="1.8"
                     /tool="antismash"
                     /translation="YGPAECS"
     CDS_motif       complement(15553..15609)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0025"
                     /evalue="1.40E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="3046"
                     /protein_start="3027"
                     /score="29.9"
                     /tool="antismash"
                     /translation="YVVFTSGSTGKPKGVVIEH"
     CDS_motif       complement(15811..15852)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0024"
                     /evalue="6.50E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="2960"
                     /protein_start="2946"
                     /score="10.2"
                     /tool="antismash"
                     /translation="MGVMKAGGAFLLLD"
     CDS_motif       complement(16430..16534)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0023"
                     /evalue="1.50E-07"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="2772"
                     /protein_start="2737"
                     /score="23.8"
                     /tool="antismash"
                     /translation="QEEYLQSLAHQSFPLSDIHRLAGVTSGVLFNTSVA"
     aSDomain        complement(16574..17434)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_6G12080_Condensation_DCL.2"
                     /domain_subtype="Condensation_DCL"
                     /evalue="3.60E-37"
                     /label="AFUA_6G12080_Condensation_DCL.2"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="2724"
                     /protein_start="2437"
                     /score="119.9"
                     /tool="antismash"
                     /translation="EDIYPCSPSQRGMLIAQAKAAHNYNASVTWSIRSRIDSRPNVARL
                     KAAWCEVVKRHAILRTVFVESPWPESYMDQVVLQNVSPEFVFCRGSDSLPQSISSPGQT
                     RWSKGQCQHIMRVWERDNGDILCRLDLSHAIMDRTTLAIIQKDLSLAYDERLLPGRAPL
                     YRDYISYIYQQDSESARQYWQGYLEGVEPCEFPTLNPVDPSITKEWGNLYRTLEDRRRL
                     EEFCRTHSVTPWNVAGLAWAMVLRSFTRTDSVCFGYVKSGRDLPIDGIAGTAGPVFNPL
                     PCRVHL"
     CDS_motif       complement(16583..16675)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0022"
                     /evalue="1.70E-05"
                     /label="C5_DCL_263-294"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="2721"
                     /protein_start="2690"
                     /score="17.3"
                     /tool="antismash"
                     /translation="VCFGYVKSGRDLPIDGIAGTAGPVFNPLPCR"
     CDS_motif       complement(16979..17038)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0021"
                     /evalue="1.50E+00"
                     /label="C3_LCL_132-143"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="2589"
                     /protein_start="2569"
                     /score="1.8"
                     /tool="antismash"
                     /translation="HAIMDRTTLAIIQKDLSLAY"
     CDS_motif       complement(17243..17332)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0020"
                     /evalue="2.00E-10"
                     /label="C2_LCL_024-062"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="2501"
                     /protein_start="2471"
                     /score="33.1"
                     /tool="antismash"
                     /translation="RIDSRPNVARLKAAWCEVVKRHAILRTVFV"
     CDS_motif       complement(17861..17923)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0019"
                     /evalue="3.50E-09"
                     /label="NRPS-E6"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="2295"
                     /protein_start="2274"
                     /score="28.9"
                     /tool="antismash"
                     /translation="VKDARRAVPCNGWAYFVSRYL"
     CDS_motif       complement(17969..18016)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0018"
                     /evalue="1.70E-07"
                     /label="NRPS-E5"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="2259"
                     /protein_start="2243"
                     /score="23.4"
                     /tool="antismash"
                     /translation="DLSQTVGWFTTMWPVV"
     aSDomain        complement(17969..18835)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_6G12080_Epimerization.1"
                     /evalue="1.20E-37"
                     /label="AFUA_6G12080_Epimerization.1"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="2259"
                     /protein_start="1970"
                     /score="120.8"
                     /tool="antismash"
                     /translation="ALSPIQQMFFDRQPSGWDRFSQVFLLRVSQPVTASQLQMALHTLV
                     SKHPMLRARFAKQHDGSWRQVITSKIQESYRCRSHRLNRRSSVDGVVSSGACSLSIQKG
                     PLIAVDLMSREDGAQYLSIVIHHLVVDLVSWRIILADLEAMLRGENPMANHSTPFQTWC
                     RLQAEYARQYLSPQHAFPTDLPDHYHQDPSVFWGLAGQPNLVRDSRRQVFTLDEHTTRQ
                     LLGAANAAFATRTDEVLHAVLLYSFLKVFPHRIAPLTFSEGHGREPWDSAIDLSQTVGW
                     FTTMWPVV"
     aSModule        17969..22000
                     /complete
                     /domains="nrpspksdomains_AFUA_6G12080_Condensation_DCL.1"
                     /domains="nrpspksdomains_AFUA_6G12080_AMP-binding.2"
                     /domains="nrpspksdomains_AFUA_6G12080_PCP.2"
                     /domains="nrpspksdomains_AFUA_6G12080_Epimerization.1"
                     /locus_tags="AFUA_6G12080"
                     /monomer_pairings="X -> D-X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(18410..18475)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0017"
                     /evalue="2.30E-09"
                     /label="NRPS-E2"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="2112"
                     /protein_start="2090"
                     /score="29.6"
                     /tool="antismash"
                     /translation="LSIVIHHLVVDLVSWRIILADL"
     CDS_motif       complement(18671..18763)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0016"
                     /evalue="6.20E-04"
                     /label="C2_DCL_024-062"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="2025"
                     /protein_start="1994"
                     /score="12.1"
                     /tool="antismash"
                     /translation="LLRVSQPVTASQLQMALHTLVSKHPMLRARF"
     aSDomain        complement(18908..19090)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_6G12080_PCP.2"
                     /evalue="1.10E-13"
                     /label="AFUA_6G12080_PCP.2"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="1946"
                     /protein_start="1885"
                     /score="43.0"
                     /tool="antismash"
                     /translation="EREMQAIWAQALNLPLAEIGMDDSFYQLGGDSITAMQVVAHARSK
                     GLAVTMDSILRLKSIS"
     CDS_motif       complement(18992..19021)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0015"
                     /evalue="7.70E-01"
                     /label="PCP_mE"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="1918"
                     /protein_start="1908"
                     /score="3.6"
                     /tool="antismash"
                     /translation="SFYQLGGDSI"
     CDS_motif       complement(19466..19531)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0014"
                     /evalue="8.70E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="1760"
                     /protein_start="1738"
                     /score="30.7"
                     /tool="antismash"
                     /translation="YIGRRDSQIKLRGQRIELDEVE"
     aSDomain        complement(19496..20680)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_6G12080_AMP-binding.2"
                     /evalue="1.60E-93"
                     /label="AFUA_6G12080_AMP-binding.2"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="1750"
                     /protein_start="1355"
                     /score="305.4"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="ERPTSTAVWAWDGQLTYAELGELSDRLAEYLATKGVQPEVIVPVC
                     LEKSYWTTVAMLGISKAGGAFALLDPSQPEQRLQSICHQLNSAVILTSEKNRDLAGKLA
                     SHPIVLSLQSSRRWGHGPAKQAPATARPDHTLYVAFTSGSTGTPKGVVIEHRSFCTSAL
                     ALNRITGVNSESRMLQFAGYSFDGSIMEMLSALMAGACVCVPSEFQRRNELVAAAAKFE
                     LTHAHLTPSVARHLLRGNPEFTKTLVSVGEPMTASDVADWASNGQCKVMNGYGPAECAV
                     STTIQAAVTSASDPKNIGFPVAGVCWVVHPENHDILLPPGAVGELLIEGPTLARGYLNE
                     PDKTAAAFIPLPAWIKDIRPEQPHGRLYKSGDLVRYNADGSFQYIGRRDSQIKLR"
     CDS_motif       complement(19637..19726)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0013"
                     /evalue="6.40E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="1703"
                     /protein_start="1673"
                     /score="50.4"
                     /tool="antismash"
                     /translation="PPGAVGELLIEGPTLARGYLNEPDKTAAAF"
     CDS_motif       complement(19832..19861)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0012"
                     /evalue="1.00E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="1638"
                     /protein_start="1628"
                     /score="5.9"
                     /tool="antismash"
                     /translation="YGPAECAVST"
     CDS_motif       complement(20216..20272)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0011"
                     /evalue="4.90E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="1510"
                     /protein_start="1491"
                     /score="28.3"
                     /tool="antismash"
                     /translation="YVAFTSGSTGTPKGVVIEH"
     CDS_motif       complement(20471..20512)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0010"
                     /evalue="2.50E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="1425"
                     /protein_start="1411"
                     /score="5.4"
                     /tool="antismash"
                     /translation="LGISKAGGAFALLD"
     CDS_motif       complement(21077..21145)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0009"
                     /evalue="4.90E+00"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="1223"
                     /protein_start="1200"
                     /score="-0.5"
                     /tool="antismash"
                     /translation="QDQSMEMIPFEQLGLRQIRKLSP"
     aSDomain        complement(21185..22000)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_6G12080_Condensation_DCL.1"
                     /domain_subtype="Condensation_DCL"
                     /evalue="8.10E-44"
                     /label="AFUA_6G12080_Condensation_DCL.1"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="1187"
                     /protein_start="915"
                     /score="141.7"
                     /tool="antismash"
                     /translation="QDIYPCTPLQEGMMTLSAAKAGSYIARFVYRLEEHVDSPRFRRAW
                     EMTVEATPILRTRIISASDGRLYQVVIQEKFRWDDDGQPSGECVQNGQDRHMLLGEPLT
                     HAALVRDRNQDGSLSTVFVLTMHHSVCDRWSVGLIMDSVETAYTGQTLTTNSMGPFLQY
                     IQQLQGGDAFWRSQFVGVKAEVFPSLPSPEYTPTPTETIDLSVELRDAVPGGHTIANAI
                     RLAWALVISHYTSCSDVVFGVTISGRAVPVPDIERIIGPIIATVPLRVRL"
     CDS_motif       complement(21194..21289)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0008"
                     /evalue="3.00E-13"
                     /label="C5_DCL_263-294"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="1184"
                     /protein_start="1152"
                     /score="42.2"
                     /tool="antismash"
                     /translation="DVVFGVTISGRAVPVPDIERIIGPIIATVPLR"
     CDS_motif       complement(21560..21625)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0007"
                     /evalue="5.20E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="1062"
                     /protein_start="1040"
                     /score="19.1"
                     /tool="antismash"
                     /translation="MHHSVCDRWSVGLIMDSVETAY"
     CDS_motif       complement(21824..21937)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0006"
                     /evalue="6.60E-11"
                     /label="C2_DCL_024-062"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="974"
                     /protein_start="936"
                     /score="34.5"
                     /tool="antismash"
                     /translation="GSYIARFVYRLEEHVDSPRFRRAWEMTVEATPILRTRI"
     aSDomain        complement(22124..22321)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_6G12080_PCP.1"
                     /evalue="3.60E-14"
                     /label="AFUA_6G12080_PCP.1"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="874"
                     /protein_start="808"
                     /score="44.6"
                     /tool="antismash"
                     /translation="ETLIHQLVVELLHLPPEMVGMNHNFFSLGGDSVSVMKLVSRAKRV
                     GLSFTVKDVFRSPQLGDLARL"
     aSModule        22124..23923
                     /complete
                     /domains="nrpspksdomains_AFUA_6G12080_AMP-binding.1"
                     /domains="nrpspksdomains_AFUA_6G12080_PCP.1"
                     /locus_tags="AFUA_6G12080"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(22223..22252)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0005"
                     /evalue="8.70E-01"
                     /label="PCP_mE"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="841"
                     /protein_start="831"
                     /score="3.5"
                     /tool="antismash"
                     /translation="NFFSLGGDSV"
     CDS_motif       complement(22715..22777)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0004"
                     /evalue="5.20E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="677"
                     /protein_start="656"
                     /score="28.3"
                     /tool="antismash"
                     /translation="YVSRKDRQVKIRGQRIDLAEP"
     aSDomain        complement(22742..23923)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_6G12080_AMP-binding.1"
                     /evalue="2.30E-81"
                     /label="AFUA_6G12080_AMP-binding.1"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="668"
                     /protein_start="274"
                     /score="265.3"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="RATDRRHHPAVIAADRALSYSELETLSLKVAYRLRGSGVQPGDLI
                     PVCFCKSSWAIVAMLAINKLGAAFVPLDPSQPVNRLKSITRQLDATLAVTSPENQSLVE
                     DLVTTTVVVSETTVSELVDVHNEIVLPACDPGAPAYCLFTSGSTGKPKGCVVDHAALAS
                     VATHSHALHLGPTSRVLQFASFTFGVSLIEVWCTLAAGGTVCLPSDSDRVSRLADAIRS
                     MGVDWCILTPTVLATLEPEAVPNLRTILVAGEPLKKAQFSLWAERARLFQAYGFTEWAG
                     ICCVSPQIRSIGDVGIIGTPANARCWLVEPGNPNQLAPIGAVAELAVEGPSLAQGYLHD
                     PEKTAATLIPPPRWRAQYGHADGKRIYTTGDLVYYDSNGMLRYVSRKDRQVKIR"
     CDS_motif       complement(22886..22969)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0003"
                     /evalue="3.00E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="620"
                     /protein_start="592"
                     /score="38.8"
                     /tool="antismash"
                     /translation="PIGAVAELAVEGPSLAQGYLHDPEKTAA"
     CDS_motif       complement(23450..23509)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0002"
                     /evalue="7.50E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="432"
                     /protein_start="412"
                     /score="27.7"
                     /tool="antismash"
                     /translation="AYCLFTSGSTGKPKGCVVDH"
     CDS_motif       complement(23705..23746)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_6G12080_0001"
                     /evalue="2.10E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="AFUA_6G12080"
                     /protein_end="347"
                     /protein_start="333"
                     /score="11.7"
                     /tool="antismash"
                     /translation="LAINKLGAAFVPLD"
ORIGIN
        1 atgcccgaag acaaggtcga agccatcgaa catgtcgaat ccagtcgcca tgatgccacg
       61 gtcaacgaga aggcgattgc ggacttcctg aacgcagaga aggagatgac gacctggcag
      121 gccgtcaggg cgcatagacg cttgttgctc tttggtgagg cccttcagca tcgactgctg
      181 gccgtctgtt ctcctgcact gcagctgctt accgagtcac acacctagct atcctcccct
      241 tcgtttgtgc gagtaactat ggctatgata ctgtctccaa cggttccagt attgccatgc
      301 cggcctttat tatgtccttt ggcgccatga atcatgccac agggtctatg tatctgccgt
      361 ctatctggac atcgctctgg acttccatga ccaacctcgg ccaggccctg ggctctctga
      421 tagccgggtt ccttgccgag cgcatcggtc gtcgctggac tgccgtgtca ctcgccatcc
      481 tttctatcgt gggcaccttc attctcgtct tctcctcgac caggggcatg ttattagtcg
      541 gcaagacgat gaatggagcc gtggtgggag gattgatggc gattgggacc acgtacgccg
      601 ccgacgtacg acattgaccc ttctctgaca acgtcgatct ggagaaatgc taacaatggt
      661 gctgctgggt aggttgctcc catcaaactc cgtggtgctc tcctgcaggc catcgtcttc
      721 ttcggcgtgg ccatgcaggg ggtgagtttg ggaatcgtgc gcgccttcat tctcgacatg
      781 agaccgcttg cttggaagat tgtctttggc atccagtggg cttttgccac cttagtcttg
      841 attgctgctt ttctcgtgcc cgagtgagtg tccctcgaac ttcttcctgg gctgatgagc
      901 cgcaactaag aacccactcg gtaggtctcc cgtcttctac gtggcacacg gaaagcatga
      961 taaggcccaa agcgcactcc ggcgcttaca cggcagttcc gaccagtacc tccacatccg
     1021 ctacggggcc atcgtccacg cgctcgacga ggagaggaaa cagcagtctg aatcagtgtc
     1081 ctgggccgag ctcttcaagg gctgcaatct caagcggacc atcactattg ggttcatcat
     1141 gtttagcacc agcgccattg gcgtgccgtt cctgacgcag aatatctatt ttctcatcac
     1201 ggtgggcctc aacgtgacca gcgttttcga catcgggatc ggcgggtttt tcctcggctg
     1261 tctctttgtg atgctcggct ggctctccaa cgaagggatc ggtcgccgga gactgtggct
     1321 ctggggctta atcggcaact tcctctgcat ggtaactatc ggtgcgttgg gattcagcac
     1381 cacgaaggcg agccagttgg caattgcggt aatcatgtca gttctgccac gctctaaact
     1441 accccggaga atttatctaa atgtcgtctt tctgcctaca ggaacgtcct catctcgtac
     1501 ggtgtctatg ccacggttgg tgtagcctgg accatctgcc ctgagatctc gtcccaccgt
     1561 cttcgccaat actcgcagtc ggttgccttc attgttggcg ccgttggcgg ttggctgttc
     1621 aattttatca ccccgtacat gtataatgtc gattcgggca atctgggcgc gaagactggc
     1681 tttgtgtatg ccgggttgac ggtggtcgtt gccgttatct cttggttcct cgttcccgag
     1741 acggcaggcc tcagcgtcga agacattgat agggcatatg agatgggaac cgcaccacga
     1801 cacttcaagt ctgccaaagc gacagtcagt gccgagagtg gacattgatg ggctacgtga
     1861 tgtaaggtca tccgtctatc agcacaccct taccgaagtt gacgtcggaa tatttggatt
     1921 agattctgcc ttggatgcgc ctctcgtcct ccagagacta ataggatatg cgaacgaagc
     1981 tatattctcc ttgttcattg accaacttac gagcgttgac ttctcgcttc cagagtcgat
     2041 gggcttgtag cagtatatac aggatatctg cccacggctt ccgccatcat gtgtctgtta
     2101 acaccaattt tatactataa cttcccaggt tatcttcttt cgttacaata caagtccctc
     2161 cagtcaagtg catttgcaaa tctgatcctt accttctgtt tgagcgccgt tgccttgata
     2221 ggtatcctgc atgtgtgcgg ccaccaggat ccagctacat gatattgcaa ttatgcacct
     2281 aagcaactat gtgtgtgtat ctaagtagtt aatgcacagc gcagcccttg ctgtatgtag
     2341 gtgcacgcct aatgcaaata gtctaaacgc aaggaagtcc aggcagccgc aaacgcccca
     2401 gccatccgat gtctcagctg tagattcaat tattccttta tctctgtcta ataccgctaa
     2461 atacagggat ctgcggcaca gtagtataac tatgtcagct aagctaatgg aagctctgta
     2521 gccggactaa cactctagag cgagccatct cagtaaccct gccatcatcg aaataacctg
     2581 actcaaccgt cgatttagat tatcgtgtat ctatttgccc tcaacaagca tcggttcacc
     2641 cctacgcctt cacaatagac tgcatttgcc gctcctccaa gggttatccc ccgtgaggag
     2701 gtaagaggtg cgtgccgcaa ggtgtactcc gtatggggca tttcgtccta aaaatatgtg
     2761 gggcccggga tggctggcac attgaaacat tctcgatctc agtggtacag cagcaagatt
     2821 cgtggactcc ggagggaccg gcccaggtgg ctgaatgaca cgagtcatat tggctccaca
     2881 ccgacttggt gacttatcgc gcactgcgtc agttccggta ttctggtctc atgaatagcc
     2941 catgaaaggt aatgtagccg cctgtgggat gcgcaacagg atggctacta gaggtgacat
     3001 ccacatgaca tactttttat gcagttacct tgatgctgcg ttgtctttct cattatggcc
     3061 cccttactgc tagaggcgga gacaacgaca cttgatcgaa tgcccgatct catccagacc
     3121 aaatcggtgg tcctaggcta cggtgtaaag atggttttgg ctccagcgaa agcagcgagg
     3181 agtcttgttt gtccctacgg gcgagcccac atggaatatt taactggtat tggtctcaag
     3241 caaactggcg agctaaccgc tgagtatccc cttgcatgat gcaacccgta caaaatctga
     3301 atggatacca gggtagaatt gagtgtatgg tcacaaacag cagcagatac ttgagttggc
     3361 tgtgtgccat gcgcttgtgg ataaccctaa caacagcagg aatggcagac tgcatccatc
     3421 cccttgcata atattggcgc aagacagact ggcggaggca acgactttac gagagacaga
     3481 aggggacgtt atatttattt tagaagaaat gattcacaaa gtaatatcca tcccaagcct
     3541 atcgtagggt ggaaggtttg tccttacacc gagtcgattt cagtgcgctc tactcgttgt
     3601 cctatgactc ccagtcagtt aatacgagaa gaagccgtct ggagattctc cctgcccaga
     3661 gtcttgtcaa cgcctacgac aatgttggag acgacggagc caattgcgca cgccagcgag
     3721 ctggacaaac ccagcatcgt tgtcacgaac accgaggtcg acagcgagga taacacttcc
     3781 tccgttctgg gccgctatat accacagaaa tgcctccaga acgcaaggct cgcagctgta
     3841 aactcgtgtg tcaacgagat cttcgaggct cgcttccggg agcggcccga cgcccccgcg
     3901 gtctgtgcct gggatggcag ctacacttac cgcgagttga acgacagatc atccgctctt
     3961 gcccacaaac tccgtcgccg gggtgtgcaa gcagaggtgt tggtggcact cctctttgag
     4021 aaatctaaat tcagcgtcgt tgcaatgcac gctgtgatca aggccggcgg cgcgtttcaa
     4081 ctgtgggacc catccttgcc tgtggctcgc ttgggaggaa tgtttgctga gtcaaaagcg
     4141 cacttggtgc tcgcatcggc cgcaaatgcc cgactggccg ctgaaatcag tgagaatgtg
     4201 atggtggtgg acgagtccct tgttcccccc tgggagtctg caccgctgaa tcctggaacg
     4261 caaccggaga atgcgctgta ctgcgtcttc acttccggct cgaccggcaa gcccaagggg
     4321 ttcttgatgg atcaccgagc gttctgcacc tgtgcactcg gcgtcggaga attactcgga
     4381 ttgaatggag cctcccggct tattcagttc tctgcgaact cgtttgatct tgcgacgttc
     4441 gatcatattc ttccgttcct gtgcggtgca tgcctctgca tcccatccga ggaagagagg
     4501 aaaggcgacc ttactcgcgc attcaacaga taccgtgcta cccatgccgt actcacgccc
     4561 acggtgagtc gtctcctgga gcccgaaaag ctcaccacct tgcaggtatt gctgctagca
     4621 ggtgaggcgc ccagcaggga agatatccgg cgttgggcct ccactgtcgg gctgctcaac
     4681 ggttacagcc ctgcagaagc tggatgcatc actattgtca acccgtcctt gcaggagagt
     4741 catccgagca agatcggatt ccccgtcagc gtggtaccct gggtagtgga cccagacgac
     4801 tgcaatcgac tagtgccggc tggagaggta ggagagctgg tactgcaggg acatacgttg
     4861 gcgcgaggat actttggacg cccggaccaa agtaaagcgg ccttcatccc gacgcctgca
     4921 tgggtacgcc aatttggcta cgagacctat ggacgtctgt acaggacggg agacctggtt
     4981 cgattcgatg ccgaggacga gtccctggtc tacatcggcc gcaaggattc ccaggtgaag
     5041 atccgcggtc agcgactgga actgggtgag gttgagcatg cgttgcagca attctttccc
     5101 cggccccaga tagtcgtggt cgagttattg acggccgagg atagggagcc agccttggtc
     5161 gggtttgtct accagcctgg aagctcgcaa catatgccag ccccgccgca gcaccaggac
     5221 aatagtcttt tcctggtggc cgatgaccag ttttgcgccg acgcccagaa agctctggca
     5281 tcgctgcggg atatattgcc cccgtacatg atcccatccg atctgctgcg gatctcccat
     5341 ctacccatgg taccgtcggg aaagactgac cgtcgattga tccggatgcg tgcggtggat
     5401 ctggcgcccg aggagaggag aaagtacagc agtgtgctcg gtcaatcccg ggaccaacca
     5461 gtaacccagc tggaagagtc gctgctgggg ctctgggcta cctgcctcaa gcttcctcct
     5521 tcgcagatcg gtgtcctgga taatttcttc cacctgggcg ggggctcact ggaagccatc
     5581 catctcgccg cggaagcccg aaacatgggg ttcgcggaat tatcctcagc agctgtgttc
     5641 cagtgtccca ccattcggga gatggcaggc atgttggacg gggtgacggc ctctgtccaa
     5701 gaacaggacc cccgcggctg cacctccttc cagctggagt cgtcactggt ggctgaattg
     5761 ctgcggaaaa gtcaatgcac gctcgaggac ctgcaagaag ggttcctacc ccttactccc
     5821 ttccaagaga aaaccgcgaa gatgaagccg atgcacctgt tgctcgacat tcccggcatc
     5881 gaccattcgc gcctcgaggc cgcttgggcg ctcgtgctag aaaaacacat cagtttccga
     5941 tccatctacg tggagcacca aggccgtgtc taccaagctt ttctgcgcca acctgacacg
     6001 gtctctattc ctatcagatg gtgcgatgaa ccagtgcatg aatgtgcggc aagattctgc
     6061 gaacaagatg tggatctgat cctggatggc cgcccctggt ggagcatgac cagaatcaac
     6121 aacaagatcg acagtgttct cgtgctccga ctgacccatg cccaatggga tgctctaacc
     6181 ctggatgtgc ttttcaaaga ctttatggcg gcctacgaga gtcgcgaact ctctcggcga
     6241 gacctggaat ttcccgccta catgcggttc cgtctgagac acaatgcgtc gccggcaaca
     6301 gtcagattct ggtcaacgtt cttgcacggt tcccggctca ctcagcccct gcttctcgat
     6361 ggcgccgcgg aggtagaccc aggaaatgag gcgatggtct ttgtgtctca gcagattccg
     6421 atgttgaccc ctcctcacgg gattaccctg ggttccgtat ttcgggccgc ctgggctttc
     6481 gtgctggccc gctacaccgg gcaagaggac gtggtctttg gcgagtttgt tgagggtcgc
     6541 tccctgctgg tgaaaagcgt ggagaaggtc actggctgcg cagctgcgga gacccccatg
     6601 cgcatcgtcg tttcgcccac ggcatcggtc cgcgacctcc tcaagcattc ccaggagcaa
     6661 tacgttgcgc gaattccgta cgagacctgc gagctggaag atatcgtgcc atccagcacc
     6721 tcctggccca ccgacaccac gttcaaccat atcctggtca tacagcatga gccagtgctt
     6781 cctcctgtgg ctctggatgg gcgtccatgc ccgcaccggt gggccttcca cggacggctc
     6841 gaggacgtct acgtccaaat ggtgttcggc ccggatacgc tgcacgttgg aatgtctggt
     6901 ccggagatcc ggctgtccag gaccattgcg acccagttgg ttgagaagct ggcgtcgaca
     6961 ataacgcaat tcaatgaccg gccagaagct ctgttatctg agattacggt gtgagaaggg
     7021 acctgagata ggtttgtggc agcaggggca gcggtgtgtt tgttaccttg tcatcttagt
     7081 agaagataac ccagaaatgt caagtagaca tctatggagc agctgcctcg ttcatcacca
     7141 cctttgtaga ggtctgtgaa gcggagttag taaagacagt ctggtcgaga tctagcagca
     7201 caaatatatc gcactcatta tagaaggtag ctactagact tgaattccgt ttctttcctg
     7261 cgggatgtaa ccttggctat tctcgaatat tgaggtacaa gtcaacagcc aggcacgcaa
     7321 gattgtctag ggccgtccgc ggtatgctac gaagaaatac agggcaagtc gagaaacagc
     7381 ttcaattctc agttcatcaa caggacccaa cacatcactc gggactatat gtgtcctcca
     7441 cccgataagc tccatccgct gggatatttc gaggaatgta ctccccctcg ccccggacag
     7501 ccctcacgac ggtgtcaaag acctgatggg tatattctcg gcagtcatgg cccagaatcc
     7561 attccggatt gggaaacgca aagacacttg ggtccttcgc gacagcctcc cagtctggcc
     7621 agaataagtg ttcctggagg gtggagctgc ccagctggat cacggtggcg cgcggatacc
     7681 tagagtttcc cgcctccatt agcacgttgt tctcttcagt cagggttgct cggatctacc
     7741 ggatcttctc tgccacgcgt agggccagcg gaacgttctc cttccccgcc aattcgagcg
     7801 ctgtagcgac caccactccg tcttcgattg cctgactgcc tccctggccg acgacgggaa
     7861 agtatgggtg agcggcatcg ccaatgagca tcacgcgtcc cccggcggac acccaggtgt
     7921 ccagcggcgg ccgatagatg agcgcgtggt ctaccagctt ctcgggcaaa gtatggcgaa
     7981 tgaccgacga gggtcgaaga cggccaggcc aagggctgag cgttgccagc gcatcgtcaa
     8041 tgcttgctcg ccctcccgcc caactctcgt gagcattgaa tttatcctag gagggtaggg
     8101 acaggcgtca gtgatgcgat ccaactatga agaacagcgc aaggatttgt ggccgttggc
     8161 tggagactgc tgtaccgtat gcatgagggc ccaagccagc tcctggcccc tcttcatcgt
     8221 catgattgcc aggttgatcc catcgccgaa ccaaacatac acccgatctt tctcccgagt
     8281 gccctgaagc acccagctcg cctccgggtc cttcgccagc tgctccgtgg tcatatgagc
     8341 gcggaaattg gcccaccccg agtgttgctg ggtgtcgacc tgcccggtca gccacgccct
     8401 tgcggcactg tggaccccgt ccgcgcaaat cacgcagtcg gcggccaggc gttcccggtc
     8461 attcacaatg actcctgcgc ggccgtcctc ttcccagtac ttggtgacac gggatcccag
     8521 tcggatgtcg atccccagct ttcgcgcatg ttcgtagagg atgctaatca accgccctcg
     8581 gttggtgaac caccctttcc ctcgcccggc cagttcatgt cggacaatga atcgatcgtg
     8641 atgatcgagc atctccgcat gcgttgcgtt ggacagatga ggctcgatct cctcgcaaag
     8701 ctgctcgccc cagctcttga tcaagcggac cgcattgggc ccgatgacaa tggcgtcgcc
     8761 cgctgccgcc ggcaatttca ttagcgagtc ctacggacag tgaaatggcg agggtgcaga
     8821 gcatgactta ccgtcttgct tcactttcgt caccttctct aagaggatca ccgaatgtcc
     8881 tctgaggtgg ctttcgattg cggcggttaa gcctccgaag cccaatccga caacgatcac
     8941 cgagatcccc gtcggggccc gcggagtcgg tagagcagtg ttgattgtca ttggaaggga
     9001 atgcggtcga aaccaggttg gtgaaacaaa tggaattccg aacggtctct ctatgtagtg
     9061 gacaaggagg attctcaagg gcgatttgag tgcaggccct cctttatctg ttgttacgga
     9121 cgggggaggc gtttgtacta accgcggtta ctcaccgttt ccaatgaaca tgtctctaga
     9181 tcctatctgt tcatggatat attgacgcaa ggggtgccac ctataatgtt tcggtgcgat
     9241 tcgtgagacg accctctcaa aggtacggga cggtccaatt gatgctggag gtgatatgag
     9301 tagtatcata gtattggata ttccagtccc ttttattggt gattagtaga aagccaatgt
     9361 ccattcagta agagagctct ggcacgtctt ccggtaatag atcagtgtat tattaggatt
     9421 ctatttcggt gacccaccgg tatacggtcc tattaaacag caaggggtaa gagacatttg
     9481 ctatgtcact tggctgggga gtcttgtatg gcattctttc ccaagaattt cccttaaatt
     9541 gtatctgtct ctccttctta ctcccagcga gtgctttttg acttttgaga accattcttg
     9601 agatcagcca tgcagtacat ccccttcctg atctcggggc tggtccctgt tgcgctatca
     9661 aagtcccttt tcgaagcgac gagcaacacc aggattgatg ggaatgatat cgccgccatc
     9721 ttcggtccgg tcttgacacc agaggcccat atcttcctcc cctccgacgg tgactacgac
     9781 gataatgtga tggctcgatg gtcgacattc aacgacccgt cctacgtcgc cactgttaag
     9841 cctgcgacgg agacagatgt ccaagcaatt gtaagcacat ctaccaaaga agcaagagat
     9901 gcggcgccgg tgatgctcag agagaatatc aggtttccac tgctgcctcg cacaatataa
     9961 cttttttcgc aactggtggc ggacacggcg taaagttgaa ctttggcaat gtgcaaaatg
    10021 ccataaatat cgaattgagc ctgcttgact tcatcgatct ggaccttgac aatgaggtgg
    10081 tcaccatcgg acccggggtg gaaaatgccc agctttatga ccttctgtcc tccgtgggga
    10141 aagagaccgg tacaaactct tacatctttt tgcccagcac tcagcttgag ttccatgtat
    10201 aagcagatac agctcactaa cgttgcaatg tagcactaac tggcgagcgc tgcgtcaaca
    10261 ccatcggccc tacgcttggg ggagggttgg ggcccctcta cggcattcgt ggcccgcagg
    10321 tagattctct tgtgtccgct cgcttggtaa cagcttccgg ggatgtgata actgtctcca
    10381 ggagcgagaa tcgagatctc ttctgggcta tcaggggtgc tggtgcgaac tttggtatcg
    10441 tcacgtcggc cacctacagg atctacgacc agaccaatgg tggaatggct gtgtccgccc
    10501 agtttgcctt cgcgcctgcc gtcaatcgct cggtattcga tctgatggaa tccatgaatg
    10561 atgagtatcc cccggggatg tctgggggga tgatactcag ctataatcat acaaccaacg
    10621 aggtaactat ccttctgggc tcccctttga gcttctcttc ttgtccttga gtggtgattt
    10681 atatccatga tagccctcgg tccaatggaa tctcttgttc atggggtcca atgaagatgc
    10741 ccagccgtgg ctcgacaaga tccaggccct gggtccgatc gactcgagta tccgcaacgt
    10801 cccgtggcat cgcagggatg aacccgaagt gccatattgt gagagaggac aacactatat
    10861 cctttacaac ctgaacctca gaagaacaga tgcagccact ttgcagtcct acttcgatag
    10921 cttcgtcgac ttctcctcca aaaacccctg gttcgattgc gatctcatgt atgaacggca
    10981 ggcgaccgac gccgcgctgg cagtgcctct tagcgagagg ggagtagggc catggcggga
    11041 cagtaaaatc aatgcgtaag tctctgtatc cattgatacc cccgtctacg ttcaccagac
    11101 atcagagaag caatggcccc tctgcggcat ggaccacgtt tagttgctca ttctccacta
    11161 acgattatat atcactgcag aaactttctc gtggtgaccc cttccgaaga gtatgatgaa
    11221 gctgctgatg ccttcgtgcg accatttatg gatcgattcc aggcagtcat gggcttcgac
    11281 actctccatg tgtacgtcaa cgaggcgctg ggtgacgaag gtcccgcgtc atggtatggg
    11341 gaggaaaacc tcccgagact tgttgcgctg aaacaacaat gggacccgga aaataaattt
    11401 ggtgccgggg ctccgattcc gttgagtctg tagcccttgg gataaattgg atttccatgg
    11461 ccatgttctt aaccttacgg ctagccgctg agcatacagc tttggctgta tcactcacca
    11521 agacccatac tcgagagcaa tagagaaaat caccttttac cgagatgtat gtgccgaaat
    11581 ttgtgtatgt ggacagggca ggagctataa tgcctggcaa acgagtaaat cctacgcctt
    11641 tgcatagttc tcatgacgag acgacttcaa cactatggca tttgtgaggt agacttggat
    11701 acagtgtgat caccaagcgg gccaccaaat cagactatct aagaaccgtt atactctaaa
    11761 ggcagggcct gactcaaggc gcgaggtccg ctctaaaata gcgcagggac aaacattgct
    11821 catttctgac cttctttgag gaaagataga tagtgctcta tccttccaga tgcacatacg
    11881 agactaaagt tatgaattct agaccagagt acatgtaaca ctgcggcagg ttggctatcg
    11941 ctgtgacaag acatgcctac tcgggtgtcc aaaaaccagg tctcaatggg gttgccctac
    12001 acctagcgac tgttgcttga gattggcaac gcagataggc ttgcagatag gctgcagtga
    12061 gggggagcgg cggctgacga agccaagggg accaactgct attctctcag ttgatcctca
    12121 tgttgggaag caaggaaaag tatagtcaca tcttacgggg gtaattcctc cggcatacag
    12181 cccacgcaaa agggagagga cgatattcta ttcaacaata gcggagactg aaaacatttc
    12241 cctttcatcg ggcttcgccc attctcgtat ctttcctgta cgatacaatc tccaggcgag
    12301 atttagagat ttagtgaaat tggtctctga gtggatgtat gattgtcaat ggatttatcg
    12361 tagtcctgct cactggatct tagatcggtc accctgtaaa actccagcca gagccctcat
    12421 tcgcaaattt ataccgcttt gctaacggca tgtgccatgt caccgagtag cttggctgag
    12481 gttgtccacg gccataccag tggatacgaa ccagctctca ttgccaggag tactaatctt
    12541 tacaggctac gttgacatat tgtttatatc tctttatgat tccctcgtga tgaggttgta
    12601 gacccccaag actcccacca aaatgtatgt caggtagctg ttagaagggc gcttctccga
    12661 aaggcaaatt ggagtcgtaa ctagtttctg gtctttatgg acggcgactg agtagtgatg
    12721 aatatccggt agctatatat agatgtatag atgtttgcct ctgtcgtgga caccaggctg
    12781 actgtcactg tacctacaag cacaaaaatg acatagcagt gctcagttta gcactttctc
    12841 ttctgcgagt agccctgggc ggtccatgtg atcgactact ttgctcagcg ggcagtctgg
    12901 tgaagcagag aagaattcga tcaggtcaca gagccgccga cacaaagctc ttgcctggtc
    12961 ctcagataag acccgggtat tggcgcacac ttggatctcc agtcggtctg ggtgaggttc
    13021 ggaaaagatc caaacttccg tcaacggatc gaactgtgcg aacttggagt attgcacctg
    13081 cagaccgtcc aaggcgatgt tgtggtgcag ctcgatattc tgatgttgga caatgaagct
    13141 gagctgggta tccgcgggcc aaggggtcga atgtctgaag atatcccgga gctcgaggtg
    13201 ctcgtgtggc agcgctcggg tgtactgttc ctgcacgtgg gcgagcagat ccaggaccgt
    13261 ccacgagggc tgcagcatca cccgcaatgg tatgaagttg aggcaacatc ccaggagagc
    13321 ttcgacatta tcaagggcca ggttccggcc gttcacggtg tgcccaaaaa ccacatcgtt
    13381 ctgggataga agctggcaga ggtggaatcc gcacgccgcc ttgacgaggg aggccattgt
    13441 gatgcccgcg ggcagacggg gattctttat gccttggaag gtccactgag tcttgtgctc
    13501 gcggtcctgg cagttcgttg cggggaacgg cacgggcata gaggagcctc ggagatattt
    13561 cttccagaaa tcaaaggcag gtcgctcgtc tcgcgaggaa cgatgataga cgtaatcggc
    13621 aaagtgggtg gttgatggca gtggtatctg gttatatatg gcggctatat cactgaaaag
    13681 acgtggaata gataccccat cccactgggc atgggagatt tggatcgtaa aaacgtgctc
    13741 ctgctctgag cgggacacga gagtgaactt gcacgggagt cttcccagtc catctaacgc
    13801 tgccagatcc ctttcccaga gcgacttgca gaactcgaga agatctccat cagtcgtata
    13861 atgggtgaaa ggggtctcca ggttatcgag gacaatctgt atcagacggc cctcgtattg
    13921 taggaacttt gttcggagaa tgctgtgtcg agacaggatc gctgtacacg tcttttgaag
    13981 ccggcatctg tccagagggc cgcggataga aaagttataa gagtggaaag tacctcgttc
    14041 aatgaaaaat tgttgagctt gtgtacccgg tagtaagtct gccagtgcag atccaggagg
    14101 gacgagaccc tgctccatca atgacatgtg caggtccttg gggctgtcta ccggactcaa
    14161 cgaaaatggc tgatgggagg tcgaggagcc attgagggac ttggggacgg ccacctttgc
    14221 gagatccgac aagacaggat gagcaaagat atcggcgacg ctcaaagcca tacccgcagc
    14281 acggcagaat gcggcagcct tcatggcgtc gatggagtca ccgccgctga gtaggaaatt
    14341 atcgtcggct ccaatatgtt ctactggcac tttgaggaca tccgcccata tttccgccag
    14401 cttcttctct tcctcggtcg acggagcccg cgtcgaacag tgcccagcat caaccgaagc
    14461 tttatacgcc tgtagttcga ttgaagacat agcagcgacg gctttcagga ggctgttcct
    14521 gtcaaccttg tctgaatgag ttcgagggat ttgggccagc ggcaagaaca tggacggcac
    14581 catgaagttg ggcaccgttt gtcgaagcct ggtttctgcg gttgtggcgc tctgcatgaa
    14641 gtccaccgag ggttctgcga tgagcttgct gtcgctttcg ggagcaatac gcgctgctcg
    14701 ctctgcattt tggaaaacca tggcgactaa ctgcggtttt ccgcccctgg aagaaggtaa
    14761 caagtctgcc actacatcca gcgccccagg gaagcaatgc tgcacgttag cctcgacctc
    14821 cccaagctct aaccgttggc cgcgcaattt gacctgacga tccttgcgcc caaggatgct
    14881 gagagagcca ctggggtttg cccgcaccag gtcgcctgtc ttgtacagac gcgaggtaca
    14941 gtgtcctcga agagtacgta gccaggttgg gggctcgatg aagacttccg ctgtcttctc
    15001 ggcgttgttg atgtaccccc ggccaacgat ggggccttca atcagcaatt ccccaacagc
    15061 accatttgga actagtttgt ggtgatcgtg agggtctacc acccaagcaa cagacccaac
    15121 ggggtaccca atatcgtgcg ggtcgctatg cgggaggacg cagggttgga ccagcgacaa
    15181 tgcagaacac tcggccgggc cgtacccgtt catgagacga acgtgttgtg cccagtagga
    15241 cacatctgtt tcctgcatgc actcaccagc caaagatagg cttgtgatgg tgctcaagtc
    15301 ctcgtgtcgg actaagcgag ccacggaagg aatgagcatg gcgtggttgg cctgcaaagc
    15361 agtggcggcc tcgcccagac tgttcttccg ttgagactcc gagatcacac agatacaacc
    15421 acctgcgatg agcacgctca gctgttccac aatgctgatg tcaaaggcgt atgacgagaa
    15481 ctgcaggacc cgggactgag gagtaagatt gtatgatcga atatgatcta gagcaccgga
    15541 gcaataggac cggtgctcga tgacaacacc ttttggcttg cccgtggagc cagacgtaaa
    15601 cacaacgtac agcgcgtcgg ctggtcgaac cttcggcatg gtaatagtat gtgaggtatt
    15661 ctccagctgc cagtgatgac gatcctcgcc cacgacgacc accgtggagg ctagttccct
    15721 gctcatggct tcatgggttg ttgaagacac caccagtctg cagtcgatat ccgcgcagat
    15781 gtccttgagg cgctgaaggg ggtatgaggg gtccagaaga agaaaggcac cgccggcctt
    15841 catgacaccc atcatggcaa tcggcgtcca ccgcgtcttt tcaaaacaaa gaggaacaac
    15901 gacattgggg ccaacgcctt gggcagctag atagactgca agccgggagg acaactcgtc
    15961 caattgcccg tatgtgaatg ccccatccca agcattgaca gcaggggagt gcgggcgctc
    16021 tacacagtgc ttctggatga gctcatgtac gcaagattcc actgcatcgg ggacgcgtct
    16081 attacgtgac caaaggatcg ccttgtcatg gtcactaaac acatcgatgg acgtcattgg
    16141 agcttcggcg ttcgccaata tggagcacag tgccttttca aatgtcgcaa ggaccgttga
    16201 ggcttggtcg gttgtgagtg tgcgcgatct gtgcctcaga tgcagcacta gttcgccgcc
    16261 ccttggaacg agggtaatga ccatatcatc ctgggcaagt tagatttggg atatccagac
    16321 acagttacag ttcgacccaa cttacctctg tcccgtcctc catggcgacg gtggtgaact
    16381 ccaggctcct cttggcctct tctgcctctg acgctacctc tgtttgaacc gcaactgatg
    16441 tgttgaagag cacgccacta gttactccgg ccaggcgatg gatatcagac agagggaacg
    16501 actgatgggc aaggctctgc aaatattctt cttgaagcct gccaatagtc tccctgactg
    16561 tcagtctctc ggtcagatgc acgcggcatg gaagaggatt gaaaaccgga ccagcagtac
    16621 cggcaatccc gtcgatcgga agatcacgac ctgattttac atagccaaag cacacactgt
    16681 cggtcctggt aaagctgcga agcaccattg cccaagcgag tcctgccacg ttccatggag
    16741 tgacactgtg cgttcggcag aactcttcca gtcttcttct gtcctcgagc gtccggtaca
    16801 gattacccca ttccttggta atggatggat caacggggtt cagcgtcggg aattcgcatg
    16861 gttcgacgcc ctctaggtaa ccttgccagt actgtctcgc gctctcagag tcttgctggt
    16921 agatgtaaga gatgtaatca cggtacagag gtgctcggcc tgggagtaga cgctcatcat
    16981 atgccagtga gagatccttc tgaatgatgg ctagcgtggt ccgatccata atagcatggc
    17041 tcaaatcaag acggcagaga atatctccat tgtccctctc ccagacccgc attatgtgct
    17101 ggcactgtcc cttcgaccac ctcgtctgcc ctgggctgga tatcgactgg ggcaaagaat
    17161 ccgagcccct gcagaacacg aattctggtg agacgttttg caatacaact tgatccatgt
    17221 aggattcagg ccacgggctc tccacaaaaa cggtgcgcag aatcgcgtgc cgtttcacta
    17281 cctcacacca ggcggctttg agacgcgcaa cattcggccg agagtcaatg cgcgatcgaa
    17341 tactccaggt cacgctggca ttgtagttgt gcgcggcttt agcctgtgca atcagcatgc
    17401 cgcgctgact gggcgagcag gggtagatgt cttcgacgtt ctcaaccgac acgcccgcag
    17461 tagggagagt cacatcgagg agttcccgga gcgtcgaata cgtcaatgga agaaggggaa
    17521 aatccgaaag agtacggctc ggcttggctg caatcaatgt gctacaccct tcgatgagcg
    17581 tttgccggca tgactctatc cacttctgaa tctcgagttg gtgcttcatg taacgattgt
    17641 acatgaactg aaactgcaag cagcctcgca ccacggacgc aaacacttca aagatgccaa
    17701 accgctgaat ctgctctcca gcatccagtg atccttggta ctcgggcata tctggaatga
    17761 agaatgcacc cgcttggttg aattgttggt actcaccagc ataattaaag accaactcga
    17821 caggatggaa ctgctggaat gcctgccggc cgctgggatt cagatagcga gacacaaagt
    17881 acgcccatcc gttacaagga accgcccggc gagcatcttt gacgcggcac acaacttcca
    17941 ggaaactatg attctgctgc agctcggcaa caactggcca catggtcgtg aaccagccga
    18001 ctgtctgtga taggtcaatg gccgagtccc atggctctct tccatgaccc tcgctaaacg
    18061 tgagcggcgc tatgcgatgc gggaaaacct tgagaaatga gtaaagaaga acagcatgca
    18121 gaacctcgtc ggtccgggtg gcgaatgcag catttgcggc gcctagaagc tgtctggttg
    18181 tgtgctcgtc gagggtgaac acttggcgcc ggctatcgcg gacaagattc ggttgtccag
    18241 caagacccca gaagactgac ggatcctgat ggtagtggtc gggaagatcc gtaggaaaag
    18301 cgtgctgtgg ggagagatat tgccgagcat actccgcctg tagtcggcac catgtttgga
    18361 aaggggtcga atggttggcc atgggatttt ctcccctaag catagcctcg aggtcggcca
    18421 ggatgatgcg ccatgagact agatccacca ctaaatgatg gattacaatg gagaggtact
    18481 gcgccccgtc ctcccgactc atcaagtcga ctgcaatcag tggccctttc tggatactga
    18541 gtgaacaggc gccggatgag acaacgccat ccacgctgga ccgacggttc aatcgatgag
    18601 aacggcagcg gtaggattcc tggattttcg aggtgatgac ttggcgccaa cttccatcgt
    18661 gctgtttcgc aaaccgcgcg cggagcatgg gatgcttcga gactagggta tgcagggcca
    18721 tttgcagctg gctcgcagtg acaggctgtg agacacgaag cagaaagacc tggctaaatc
    18781 ggtcccagcc actgggttgc cggtcaaaga acatctgttg aatcggggag agggcaaacc
    18841 acacatcctc ctcttcgtct atgtgcacga ttgccggtga caatgaactc tcatgggaca
    18901 taattttgga gatggacttg aggcgcagaa tactatccat tgttacggcc aaccctttgg
    18961 accgtgcgtg agcgactacc tgcatagccg tgatggagtc acctcccagt tgatagaagc
    19021 tatcatccat tccaatctca gctagaggta agtttaatgc ctgtgcccag attgcctgca
    19081 tctcccgctc cgcgactgat gtgggttctc gtttcgtacc ggttcctacg gcgccatacg
    19141 ccgccagctt ctcccgtgta caggccgtgg ctatactcct caaccggcgg cgatccgtct
    19201 tgccagacgc actttgcggc agaacaagaa gagggataaa gatctcgggc accatgaatg
    19261 cgggaatagc ttcgcgcaac cgagcctgcg ctacagcgac ttgtccagtg aactcctggg
    19321 ttggtgccgc taggatgtcc ccggtggtat cgacatgctc ctccaccacg acaaaggcca
    19381 cgagagtttg cgtggcagga gtgaagctga ccatctcaac ggcaacgact gcgataaccc
    19441 ccggccagca ttgatagaca tgtttctcga cttcatccaa ctcaatccgc tggccacgta
    19501 gcttgatttg gctgtcccga cggccgatat actgaaagga gccgtccgcg ttatatcgta
    19561 ccaagtcacc agacttgtac agtcgcccgt gaggttgttc aggccgaata tcctttatcc
    19621 atgctggtag agggataaat gcggcggctg tcttgtccgg ctcgttgaga tagccgcgag
    19681 cgagagtggg cccttcgatc agaagctctc ccacagcgcc aggcggcagc agaatatcat
    19741 ggttttcagg atgcaccacc cagcagacac ctgccactgg aaatccaatg tttttcgggt
    19801 cggaggcgga tgtcaccgcc gcctggatcg tggtcgacac cgcgcactcc gcaggcccgt
    19861 acccattcat caccttacac tgtccattac tggcccagtc ggcaacgtca gacgctgtca
    19921 tgggctctcc cacgctcacc aaggtctttg taaactcggg atttcctctc aggaggtggc
    19981 gtgctacaga aggagtgaga tgggcatgag tgagctcgaa cttcgcagcc gctgccacca
    20041 attcattccg tcgctgaaat tccgagggca cacagacaca agcaccggcc atcagggcgc
    20101 tgagcatctc cattatgctg ccgtcaaagg aatatccggc aaattgcagc attctcgact
    20161 cactgttgac gccagtgatt cggttcagcg ccagtgcact cgtgcagaat gatcgatgct
    20221 cgatgaccac ccccttgggt gttccagtgg atcctgatgt gaaggcaaca tataacgtgt
    20281 ggtccggcct ggctgtagcc ggtgcctgtt ttgctggccc atgaccccag cggcgggagc
    20341 tctgcaggct cagcacaatg ggatgagatg ccagcttgcc ggccagatcg cgatttttct
    20401 cggaggtcaa gattacagcg gagttaagtt ggtggcagat actctgcaac ctttgttccg
    20461 gttgagaggg gtctagaagg gcaaatgccc cgccagcctt gctgattccc agcatggcga
    20521 cggtggtcca gtatgacttc tccaggcaga cgggaacgat gacttctggc tggacccctt
    20581 tggtggccaa gtattccgct aggcgatcgg acagctcccc aagttctgca taggtcaact
    20641 ggccatccca ggcccacacg gcggtagagg taggacgctc gatctgacgc tgctgtatga
    20701 tttcatggac acattggtga gaggcgggcg gcacgatgcc gttccattgg cgcagtaact
    20761 gcttttcccc aggactaacc actggaatct ccgctacgcg agcatcggga tgcgccagaa
    20821 ggtattgcag cgtgtacacg aagtggtgaa cgattcgctg cataataggg gcctggatga
    20881 ctttgggatc gaactctgtc ctcacatcga tctgactgga tcccaccagc tgacagatca
    20941 tcgagagagc gtacgccgcg aagccaccct ctgcagccgc accggcctcg cacgttgcga
    21001 ataggctacg gttctcgtca ccccacgccg gctgtacgac gagctggctc tggaagttgc
    21061 aagcttcttc cgcctctggg ctcagtttcc gaatctgtcg aagccccaac tgctcaaacg
    21121 gaatcatttc catcgactgg tcttggatgg ctttcaatgc ttccagaaca gtagagctct
    21181 ctttcaggcg cacacgcaga ggaaccgtgg ctatgatcgg gccaataatg cgttctatgt
    21241 cgggcacagg gacggcgcgt ccagatattg tgacgccgaa aaccacatca gagcagcttg
    21301 tatagtggct aatcaccaga gcccacgcca gtctgattgc attggctatt gtgtggcccc
    21361 cgggaacagc gtcccgtagc tcgaccgata ggtcaatcgt ctctgttggc gttggggtgt
    21421 attccgggga tgggagagaa ggaaacacct ccgccttcac gccgacaaac tgggacctcc
    21481 agaacgcgtc tcctccctga agctgctgga tatactgcag gaagggaccc atgctgttcg
    21541 ttgttaacgt ctggcccgta taggccgtct caacgctgtc cattataagc ccgacggacc
    21601 aacgatcaca gacagagtgg tgcatcgtca ggacaaagac ggtggacaaa gacccatctt
    21661 gattccggtc acggacgaga gcggcgtgag tcaagggctc cccaagcagc atgtgtctgt
    21721 cctggccgtt ttgaacgcac tctcccgagg gttgcccatc gtcatcccac cgaaacttct
    21781 cttgaatgac aacctggtac agccgaccat cagaggcaga tataatcctg gtacgaagga
    21841 ttggggttgc ctcgacagtc atctcccacg ctctgcggaa gcgaggggaa tcgacgtgct
    21901 cctctaaacg ataaacaaac cgggcaatgt agctgcccgc cttagctgct gacagtgtca
    21961 tcatcccttc ctgcagtggc gtgcagggat agatatcctg gatcatgctg ctttccacct
    22021 ggcatatctt ggctgccatg gaaaggagac cgggctgcgc accgcgatcc agcagagaga
    22081 agggcggcat atgttgtgcg gctcctgagt tgaccacatc ggtcaaacgt gctagatcac
    22141 caagctgtgg cgagcgaaag acatccttca ccgtgaaaga gagcccgacg cgctttgccc
    22201 gactcaccag tttcattacg ctcacagagt ccccgccaag cgagaagaaa ttgtggttca
    22261 tgccgaccat ctccggcggc agatggagga gttcaactac cagctggtgg attagggtct
    22321 ccttgtgggt attcggcgga aggacacggg tttcaagtcc tgctaaggcc accagctcat
    22381 cgtgccgcag cgcctcagcc gcttcccgca gcttctgccg cgcaatcttg ccggtgattg
    22441 tgacaggcgt ctccttgagc tgcagaaaga gtcgggggac catgtagtct ggaagcttgt
    22501 cctccaagaa ggacgtcagt tgtcggactg aagatgtgaa gtgatcatct ggcaccgcaa
    22561 acaacggtga gtcgtgccct ccattgctag aactttcatc tctcgaggga agaacaaagg
    22621 caactagaat ggcgtctcca ttactatccg cggggacaat ggcatcaagc accacattgc
    22681 gaatcgtgca gcaagcctgc gcgatatgat attccggctc ggccaagtct atgcgttgcc
    22741 cacggatctt gacctgccgg tcttttcgac taacgtaccg cagcattcca ttcgaatcgt
    22801 agtagaccag atcaccagta gtatagatcc gcttgccgtc ggcatgtcca tattgcgccc
    22861 gccagcgcgg tggcgggatc aaagttgccg ccgttttctc aggatcatgc aaatagccct
    22921 gcgccagact tggcccttct accgccaatt ccgctacagc accaatggga gcaagctggt
    22981 tcggattccc cggttcgact agccagcatc gagcattggc aggcgttcca atgatgccaa
    23041 cgtccccaat agacctgatc tgcggcgaca cgcagcagat tcctgcccat tccgtgaacc
    23101 catacgcttg aaacaggcga gcacgctcag cccagaggga gaactgggcc tttttcagag
    23161 gctctccagc cacgaggatg gtgcgcagat ttggaacagc ctcgggctcg agcgtggcaa
    23221 gcaccgtcgg ggtcaggatg caccagtcta ctcccatcga tctgattgca tccgctagac
    23281 ggctcacgcg gtctgagtcg gacgggagac acaccgtacc tcctgcagcg agtgtgcacc
    23341 agacctcaat cagagacacc ccgaaagtga aggatgcgaa ctgtagcact cggcttgtcg
    23401 gtcccagatg tagtgcgtgg gaatgggtcg cgacgctagc caacgccgcg tgatctacta
    23461 cgcatccctt gggttttcct gtacttcccg aagtgaaaag acaatacgct ggcgcccccg
    23521 ggtcacacgc tggcaggaca atctcgttat ggacgtccac cagctccgac acagtggtct
    23581 cggaaacaac caccgtagtc gtgaccaggt cctctaccag actttgattc tctggcgatg
    23641 taacagctag tgtggcgtcc aactgccttg ttattgattt cagccggttc accggctgtg
    23701 atggatccaa tggtacaaag gcggctccaa gcttgttgat tgccagcatg gccacgattg
    23761 cccatgaaga tttgcaaaag cacacgggga tcaggtcgcc gggctgcaca ccagatcctc
    23821 gcaggcgata cgcaaccttc aaggagagcg tctctagctc actgtatgag agcgcgcggt
    23881 ctgccgcaat gactgcagga tggtgccgtc gatccgtggc tcggtcatgg acaacttggt
    23941 gcatcgcctt gaacttaggc tggactaaag cacgctcgtt ccatttccca atctggtcca
    24001 actgccttcg gctcactaag caaatctcac tcaggggaat acctcttccc gccctagcaa
    24061 gctcgacgac ttcttcgaag gaggacttca gatgcgtagc ttggatatcg gtcagcacgg
    24121 tggttttgta tgcaagaaaa catttccgcc aattggagtc gagatcgagt tccagaacta
    24181 acagcacatt gcaagccttc atccggtctg gtcagccctt cattcgagga gaatccgtca
    24241 ggagccatca ttagggtgcg tacctctccg tttgccttgc gcaattgatt gggactgcga
    24301 cacttggcca agcagtcctg cgagtttcca cggcatatca cgatcccagt atcgaagtac
    24361 gaatagcagg ttgggtcggc atccgaaatc gaccatgtat ccccttgcca tagctcgttc
    24421 agcagttgga cctgtctccg ggatgctgcc agcactttca ttcccctctt aagcccggcc
    24481 tctagtatgt cttcgttagc ccctggcggt atgtcttgca aaccaatctg cactgtgtcc
    24541 acttccgcaa agcgccagag aaggagggcc caagccgccg cggcaaggta ccgaggatct
    24601 gctccggctg taggacaagt tgtccggcac aacttgaggc ctttttctcc gctggaaatc
    24661 gccagctctg tgactctcca ttcatcgacg agcagtttcc catcgttccg tacgggaaag
    24721 aggcactttt catcacgcaa cactgaatat cgctgtgggg ccattctttc tccgtgcttt
    24781 gtagtttgat tctttgcttc caaacgttcc at
//
