BGC0000363: glycopeptidolipid biosynthetic gene cluster from Mycobacteroides chelonae
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 39,983 nt. (total: 39,983 nt).
This entry is originally from NCBI GenBank AM231612.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000363
Short description glycopeptidolipid biosynthetic gene cluster from Mycobacteroides chelonae
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
AM231612.1
via
Compounds
  • glycopeptidolipid
Species Mycobacteroides chelonae [taxonomy]
References
Chemical products information
glycopeptidolipid Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAJ77679.1
  • mmps4
1 - 417 (+) mmps4 protein
    copy AA seq
    copy Nt seq
    • CAJ77680.1
    • mmpl4a
    414 - 3293 (+) Mmpl4a protein
      copy AA seq
      copy Nt seq
      • CAJ77681.1
      • mmpl4b
      3303 - 6236 (+) Mmpl4b protein
        copy AA seq
        copy Nt seq
        • CAJ77682.1
        • rv1174c
        6332 - 6670 (-) Rv1174c protein
          copy AA seq
          copy Nt seq
          • CAJ77683.1
          • rmlA
          6806 - 7672 (-) RmlA protein
            copy AA seq
            copy Nt seq
            • CAJ77684.1
            • gtf3
            8234 - 9397 (+) Gtf3 protein
              copy AA seq
              copy Nt seq
              • CAJ77685.1
              • rmlB
              9493 - 10611 (+) RmlB protein
                copy AA seq
                copy Nt seq
                • CAJ77686.1
                • atf2
                10776 - 11903 (+) Atf2 protein
                  copy AA seq
                  copy Nt seq
                  • CAJ77687.1
                  • rmt2
                  11974 - 12828 (+) Rmt2 protein
                    copy AA seq
                    copy Nt seq
                    • CAJ77688.1
                    • rmt4
                    13042 - 13848 (+) Rmt4 protein
                      copy AA seq
                      copy Nt seq
                      • CAJ77689.1
                      • gtf1
                      13898 - 15166 (+) Gtf1 protein
                        copy AA seq
                        copy Nt seq
                        • CAJ77690.1
                        • atf1
                        15154 - 16287 (+) atf1 protein
                          copy AA seq
                          copy Nt seq
                          • CAJ77691.1
                          • rmt3
                          16402 - 17190 (+) Rmt3 protein
                            copy AA seq
                            copy Nt seq
                            • CAJ77692.1
                            • gtf2
                            17194 - 18453 (-) Gtf2 protein
                              copy AA seq
                              copy Nt seq
                              • CAJ77693.1
                              • fmt
                              18592 - 19413 (+) Fmt protein
                                copy AA seq
                                copy Nt seq
                                • CAJ77694.1
                                • mbtH
                                20656 - 20886 (+) MbtH protein
                                  copy AA seq
                                  copy Nt seq
                                  • CAJ77695.1
                                  • mps1
                                  20910 - 31286 (+) MPS1 protein
                                    copy AA seq
                                    copy Nt seq
                                    • CAJ77696.1
                                    • mps2
                                    31283 - 39013 (+) MPS2 protein
                                      copy AA seq
                                      copy Nt seq
                                      • CAJ77697.1
                                      • gap
                                      39180 - 39983 (+) gap protein
                                        copy AA seq
                                        copy Nt seq
                                        Biosynthesis information

                                        Biosynthetic modules

                                        Name
                                        Unk01
                                        Type
                                        nrps-type1
                                        Genes
                                        mps1
                                        Substrates
                                        phenylalanine (evidence: Structure-based inference [1], [2])
                                        Integrated Monomers
                                        Domains
                                        adenylation
                                        Name
                                        Unk02
                                        Type
                                        nrps-type1
                                        Genes
                                        mps1
                                        Substrates
                                        threonine (evidence: Structure-based inference [1], [2])
                                        Integrated Monomers
                                        Domains
                                        adenylation
                                        Name
                                        Unk03
                                        Type
                                        nrps-type1
                                        Genes
                                        mps2
                                        Substrates
                                        alanine (evidence: Structure-based inference [1], [2])
                                        Integrated Monomers
                                        Domains
                                        adenylation
                                        Name
                                        Unk04
                                        Type
                                        nrps-type1
                                        Genes
                                        mps2
                                        Substrates
                                        alaninol (evidence: Structure-based inference [1], [2])
                                        Integrated Monomers
                                        Domains
                                        adenylation
                                        Annotation changelog

                                        Entry version: 3

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        Added NRP substrate specificities
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 2

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        Migrated from v1.4
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 1

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        Submitted
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        Detailed domain annotation
                                        Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                        A domain glossary is available here, and an explanation of the visualisation is available here.
                                        Selected features only
                                        Show module domains
                                        Similar known gene clusters from MIBiG 4.0
                                        Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                        Click on reference genes to show details of similarities to genes within the current region.
                                        Click on an accession to open that entry in the MiBIG database.