BGC0000364: glycopeptidolipid biosynthetic gene cluster from Mycobacteroides abscessus
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Location: 1 - 40,072 nt. (total: 40,072 nt).
This entry is originally from NCBI GenBank AM231618.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000364
Short description glycopeptidolipid biosynthetic gene cluster from Mycobacteroides abscessus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
AM231618.1
via
Compounds
  • glycopeptidolipid
Species Mycobacteroides abscessus [taxonomy]
References
Chemical products information
glycopeptidolipid Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAJ77699.1
  • mmps4
 1 - 417 (+) Mmps4 protein
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    • CAJ77700.1
    • mmpl4a
    		 414 - 3293 (+) Mmpl4a protein
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      • CAJ77701.1
      • mmpl4b
      		 3293 - 6256 (+) Mmpl4b protein
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        • CAJ77702.1
        • rv1174c
        		 6363 - 6701 (-) Rv1174c protein
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          • CAJ77703.1
          • rmlA
          		 6838 - 7704 (-) RmlA protein
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            • CAJ77704.1
            • gtf3
            		 8104 - 9426 (+) Gtf3 protein
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              • CAJ77705.1
              • rmlB
              		 9589 - 10650 (+) RmlB protein
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                • CAJ77706.1
                • atf2
                		 10818 - 11948 (+) Atf2 protein
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                  • CAJ77707.1
                  • rmt2
                  		 12181 - 12873 (+) Rmt2 protein
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                    • CAJ77708.1
                    • rmt4
                    		 13084 - 13890 (+) Rmt4 protein
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                      • CAJ77709.1
                      • gtf1
                      		 13940 - 15208 (+) Gtf1 protein
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                        • CAJ77710.1
                        • atf1
                        		 15205 - 16329 (+) Atf1 protein
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                          • CAJ77711.1
                          • rmt3
                          		 16443 - 17231 (+) Rmt3 protein
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                            • CAJ77712.1
                            • gtf2
                            		 17243 - 18496 (-) Gtf2 protein
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                              • CAJ77713.1
                              • fmt
                              		 18672 - 19475 (+) Fmt protein
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                                • CAJ77714.1
                                • mbtH
                                		 20746 - 20976 (+) MbtH protein
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                                  • CAJ77715.1
                                  • mps1
                                  		 21000 - 31364 (+) Mps1 protein
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                                    • CAJ77716.1
                                    • mps2
                                    		 31361 - 39106 (+) Mps2 protein
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                                      • CAJ77717.1
                                      • gap
                                      		 39269 - 40072 (+) gap protein
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                                        Biosynthesis information

                                        Biosynthetic modules

                                        Name
                                        Unk01
                                        Type
                                        nrps-type1
                                        Genes
                                        mps1
                                        Substrates
                                        phenylalanine (evidence: Structure-based inference [1], [2])
                                        Integrated Monomers
                                        Domains
                                        adenylation
                                        Name
                                        Unk02
                                        Type
                                        nrps-type1
                                        Genes
                                        mps1
                                        Substrates
                                        threonine (evidence: Structure-based inference [1], [2])
                                        Integrated Monomers
                                        Domains
                                        adenylation
                                        Name
                                        Unk03
                                        Type
                                        nrps-type1
                                        Genes
                                        mps2
                                        Substrates
                                        alanine (evidence: Structure-based inference [1], [2])
                                        Integrated Monomers
                                        Domains
                                        adenylation
                                        Name
                                        Unk04
                                        Type
                                        nrps-type1
                                        Genes
                                        mps2
                                        Substrates
                                        alaninol (evidence: Structure-based inference [1], [2])
                                        Integrated Monomers
                                        Domains
                                        adenylation
                                        Annotation changelog

                                        Entry version: 3

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2022-09-15
                                        Added NRP substrate specificities
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 2

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2019-10-16
                                        Migrated from v1.4
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 1

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2015-06-12
                                        Submitted
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        Detailed domain annotation
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