BGC0000367: gramicidin biosynthetic gene cluster from Brevibacillus brevis NBRC 100599
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Location: 3,011,718 - 3,073,069 nt. (total: 61,352 nt).
This entry is originally from NCBI GenBank AP008955.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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Gene details
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General
Compounds
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000367
Short description gramicidin biosynthetic gene cluster from Brevibacillus brevis NBRC 100599
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: AP008955.1
Compounds
  • gramicidin
Species Brevibacillus brevis NBRC 100599 [taxonomy]
References
Chemical products information
gramicidin
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C99H140N20O17
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BBR47_28840
  • BAH43861.1
  • sdpI
 3011718 - 3012341 (+) immunity protein SdpI homolog
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  • BBR47_28850
  • BAH43862.1
 3012343 - 3013098 (+) putative membrane-bound metalloprotease
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  • BBR47_28860
  • BAH43863.1
 3013336 - 3016455 (+) putative efflux system
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  • BBR47_28870
  • BAH43864.1
 3016480 - 3017814 (+) putative efflux system
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  • BBR47_28880
  • BAH43865.1
  • lgrE
 3017836 - 3018618 (+) putative type II thioesterase
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  • BBR47_28890
  • BAH43866.1
 3018618 - 3020159 (+) conserved hypothetical protein
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  • BBR47_28900
  • BAH43867.1
 3020244 - 3021008 (-) hypothetical membrane protein
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  • BBR47_28910
  • BAH43868.1
 3021010 - 3021945 (-) probable ABC transporter ATP binding protein
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  • BBR47_28920
  • BAH43869.1
  • lgrA
 3022439 - 3029266 (+) linear pentadecapeptide gramicidin synthetase LgrA
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  • BBR47_28930
  • BAH43870.1
  • lgrB
 3029271 - 3052508 (+) putative linear pentadecapeptide gramicidin synthetase LgrB
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  • BBR47_28940
  • BAH43871.1
  • lgrC
 3052513 - 3071712 (+) truncated linear pentadecapeptide gramicidin synthetase LgrC
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  • BBR47_28950
  • BAH43872.1
 3071726 - 3073069 (-) putative integrase
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated reference publication(s) (MIBiG Annotathon)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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