BGC0000379: glycinocin A biosynthetic gene cluster from Streptomyces viridochromogenes
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 88,912 nt. (total: 88,912 nt).
This entry is originally from NCBI GenBank HM756254.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000379
Short description glycinocin A biosynthetic gene cluster from Streptomyces viridochromogenes
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: HM756254.1
Compounds
  • glycinocin A
Species Streptomyces viridochromogenes [taxonomy]
References
Chemical products information
glycinocin A
Copy SMILES
C57H90N12O19
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AEG64672.1
 36 - 1925 (-) ABC transporter-like protein
copy AA seq
copy Nt seq
  • AEG64673.1
 2193 - 3959 (-) sodium/hydrogen exchanger
copy AA seq
copy Nt seq
  • AEG64674.1
 3976 - 4926 (-) integral membrane protein
copy AA seq
copy Nt seq
  • AEG64675.1
 5088 - 6905 (+) glycosyl hydrolase
copy AA seq
copy Nt seq
  • AEG64676.1
 6910 - 7854 (+) cyclase
copy AA seq
copy Nt seq
  • AEG64677.1
 7936 - 9516 (+) putative choline dehydrogenase
copy AA seq
copy Nt seq
  • AEG64678.1
 9522 - 10562 (-) cytochrome d ubiquinol oxidase subunit II
copy AA seq
copy Nt seq
  • AEG64679.1
 10562 - 12010 (-) cytochrome bd-I oxidase subunit I
copy AA seq
copy Nt seq
  • AEG64680.1
 12039 - 13379 (-) NADH dehydrogenase
copy AA seq
copy Nt seq
  • AEG64681.1
 13386 - 14228 (-) 2-deoxy-D-gluconate 3-dehydrogenase
copy AA seq
copy Nt seq
  • AEG64682.1
 14403 - 15320 (-) LysR-type transcriptional regulator
copy AA seq
copy Nt seq
  • AEG64683.1
 15806 - 16465 (+) HAD superfamily (subfamily IIIB) phosphatase
copy AA seq
copy Nt seq
  • AEG64684.1
 16883 - 17719 (+) regulatory protein A
copy AA seq
copy Nt seq
  • AEG64685.1
 17743 - 18837 (+) Daunorubicin resistance ABC transporter ATPase subunit
copy AA seq
copy Nt seq
  • AEG64686.1
  • dabA
 18942 - 20018 (+) diaminobutyric acid synthase A
copy AA seq
copy Nt seq
  • AEG64687.1
  • dabB
 20102 - 21520 (+) diaminobutyric acid synthase B
copy AA seq
copy Nt seq
  • AEG64688.1
  • dabC
 21517 - 22791 (+) diaminobutyric acid synthase C
copy AA seq
copy Nt seq
  • AEG64689.1
  • lpmA
 22788 - 25616 (+) LpmA
copy AA seq
copy Nt seq
  • AEF16019.1
 25748 - 26695 (-) regulatory protein B
copy AA seq
copy Nt seq
  • AEF16020.1
 26737 - 27579 (-) ABC transporter protein
copy AA seq
copy Nt seq
  • AEF16021.1
 27878 - 29701 (+) acyl-CoA synthase
copy AA seq
copy Nt seq
  • AEG64690.1
 29698 - 31437 (+) acyl-CoA dehydrogenase
copy AA seq
copy Nt seq
  • AEF16023.1
 31434 - 32240 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AEF16024.1
 32261 - 32542 (+) acyl carrier protein
copy AA seq
copy Nt seq
  • AEG64696.1
  • lpmB
 32712 - 42275 (+) LpmB
copy AA seq
copy Nt seq
  • AEG64697.1
  • lpmC
 42386 - 62701 (+) LpmC
copy AA seq
copy Nt seq
  • AEG64698.1
  • lpmD
 62701 - 69918 (+) LpmD
copy AA seq
copy Nt seq
  • AEG64691.1
 69950 - 70174 (+) MbtH-like protein
copy AA seq
copy Nt seq
  • AEF16028.1
 70265 - 71071 (+) LipE-like protein
copy AA seq
copy Nt seq
  • AEF16029.1
 71176 - 73497 (-) putative drug exporter
copy AA seq
copy Nt seq
  • AEF16030.1
 73752 - 74780 (+) lysine cyclodeaminase
copy AA seq
copy Nt seq
  • AEF16031.1
 74978 - 75622 (-) regulatory protein C
copy AA seq
copy Nt seq
  • AEF16032.1
 75613 - 76899 (-) regulatory protein D
copy AA seq
copy Nt seq
  • AEF16033.1
 76908 - 77711 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AEF16034.1
 77739 - 79493 (-) VanW family protein
copy AA seq
copy Nt seq
  • AEF16035.1
 79616 - 80737 (-) integral membrane protein
copy AA seq
copy Nt seq
  • AEF16036.1
 81132 - 82637 (-) integral membrane protein
copy AA seq
copy Nt seq
  • AEF16037.1
 82645 - 83184 (-) integral membrane protein
copy AA seq
copy Nt seq
  • AEF16038.1
 83181 - 84137 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AEG64692.1
 84295 - 85956 (+) two component system histidine kinase
copy AA seq
copy Nt seq
  • AEG64693.1
 85953 - 86636 (+) two component system response regulator
copy AA seq
copy Nt seq
  • AEG64694.1
 86903 - 87937 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AEG64695.1
 88235 - 88912 (+) response regulator
copy AA seq
copy Nt seq
NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
lpmA
Module ?
Specificity: aspartic acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
lpmB
Module ?
Specificity: 2,3-diaminopropionic acid
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: pipecolic acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
lpmC
Module ?
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: aspartic acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: aspartic acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: allo-threonine / threonine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
lpmD
Module ?
Specificity: isoleucine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: proline
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.