BGC0000379: glycinocin A biosynthetic gene cluster from Streptomyces viridochromogenes
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Location: 1 - 88,912 nt. (total: 88,912 nt).
This entry is originally from NCBI GenBank HM756254.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000379
Short description glycinocin A biosynthetic gene cluster from Streptomyces viridochromogenes
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: HM756254.1
Compounds
  • glycinocin A
Species Streptomyces viridochromogenes [taxonomy]
References
Chemical products information
glycinocin A
Copy SMILES
C57H90N12O19
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AEG64672.1
36 - 1925 (-) ABC transporter-like protein
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  • AEG64673.1
2193 - 3959 (-) sodium/hydrogen exchanger
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  • AEG64674.1
3976 - 4926 (-) integral membrane protein
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  • AEG64675.1
5088 - 6905 (+) glycosyl hydrolase
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  • AEG64676.1
6910 - 7854 (+) cyclase
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  • AEG64677.1
7936 - 9516 (+) putative choline dehydrogenase
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  • AEG64678.1
9522 - 10562 (-) cytochrome d ubiquinol oxidase subunit II
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  • AEG64679.1
10562 - 12010 (-) cytochrome bd-I oxidase subunit I
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  • AEG64680.1
12039 - 13379 (-) NADH dehydrogenase
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  • AEG64681.1
13386 - 14228 (-) 2-deoxy-D-gluconate 3-dehydrogenase
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  • AEG64682.1
14403 - 15320 (-) LysR-type transcriptional regulator
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  • AEG64683.1
15806 - 16465 (+) HAD superfamily (subfamily IIIB) phosphatase
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  • AEG64684.1
16883 - 17719 (+) regulatory protein A
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  • AEG64685.1
17743 - 18837 (+) Daunorubicin resistance ABC transporter ATPase subunit
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  • AEG64686.1
  • dabA
18942 - 20018 (+) diaminobutyric acid synthase A
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  • AEG64687.1
  • dabB
20102 - 21520 (+) diaminobutyric acid synthase B
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  • AEG64688.1
  • dabC
21517 - 22791 (+) diaminobutyric acid synthase C
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  • AEG64689.1
  • lpmA
22788 - 25616 (+) LpmA
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  • AEF16019.1
25748 - 26695 (-) regulatory protein B
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  • AEF16020.1
26737 - 27579 (-) ABC transporter protein
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  • AEF16021.1
27878 - 29701 (+) acyl-CoA synthase
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  • AEG64690.1
29698 - 31437 (+) acyl-CoA dehydrogenase
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  • AEF16023.1
31434 - 32240 (+) hypothetical protein
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  • AEF16024.1
32261 - 32542 (+) acyl carrier protein
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  • AEG64696.1
  • lpmB
32712 - 42275 (+) LpmB
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  • AEG64697.1
  • lpmC
42386 - 62701 (+) LpmC
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  • AEG64698.1
  • lpmD
62701 - 69918 (+) LpmD
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  • AEG64691.1
69950 - 70174 (+) MbtH-like protein
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  • AEF16028.1
70265 - 71071 (+) LipE-like protein
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  • AEF16029.1
71176 - 73497 (-) putative drug exporter
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  • AEF16030.1
73752 - 74780 (+) lysine cyclodeaminase
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  • AEF16031.1
74978 - 75622 (-) regulatory protein C
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  • AEF16032.1
75613 - 76899 (-) regulatory protein D
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  • AEF16033.1
76908 - 77711 (-) hypothetical protein
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  • AEF16034.1
77739 - 79493 (-) VanW family protein
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  • AEF16035.1
79616 - 80737 (-) integral membrane protein
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  • AEF16036.1
81132 - 82637 (-) integral membrane protein
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  • AEF16037.1
82645 - 83184 (-) integral membrane protein
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  • AEF16038.1
83181 - 84137 (-) hypothetical protein
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  • AEG64692.1
84295 - 85956 (+) two component system histidine kinase
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  • AEG64693.1
85953 - 86636 (+) two component system response regulator
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  • AEG64694.1
86903 - 87937 (+) hypothetical protein
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  • AEG64695.1
88235 - 88912 (+) response regulator
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
lpmA
Module ?
Specificity: aspartic acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
lpmB
Module ?
Specificity: 2,3-diaminopropionic acid
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: pipecolic acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
lpmC
Module ?
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: aspartic acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: aspartic acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: allo-threonine / threonine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
lpmD
Module ?
Specificity: isoleucine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: proline
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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