BGC0000382: lipstatin biosynthetic gene cluster from Streptomyces toxytricini
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Location: 1 - 19,400 nt. (total: 19,400 nt).
This entry is originally from NCBI GenBank KJ872771.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000382
Short description lipstatin biosynthetic gene cluster from Streptomyces toxytricini
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
KJ872771.1
via
Compounds
  • lipstatin
Species Streptomyces toxytricini [taxonomy]
References
Chemical products information
lipstatin Evidence:
Copy SMILES
C29H49N1O5
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AIT38298.1
  • lstA
 456 - 1580 (+) LstA
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    • AIT38299.1
    • lstB
    		 1587 - 2453 (+) LstB
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      • AIT38300.1
      • lstC
      		 2459 - 5083 (+) LstC
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        • AIT38301.1
        • lstD
        		 5080 - 6771 (+) LstD
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          • AIT38302.1
          • lstE
          		 6768 - 11513 (+) LstE
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            • AIT38303.1
            • lstF
            		 11510 - 12202 (+) LstF
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              • AIT38304.1
              		 12714 - 13334 (+) hypothetical protein
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                • AIT38305.1
                		 13464 - 14072 (+) hypothetical protein
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                  • AIT38306.1
                  		 14069 - 14989 (+) hypothetical protein
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                    • AIT38307.1
                    		 15136 - 15942 (+) hypothetical protein
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                      • AIT38308.1
                      		 15965 - 16858 (-) hypothetical protein
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                        • AIT38309.1
                        		 16988 - 17587 (+) hypothetical protein
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                          • AIT38310.1
                          		 17624 - 18094 (+) hypothetical protein
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                            • AIT38311.1
                            		 18174 - 19364 (-) hypothetical protein
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                              Biosynthesis information

                              Biosynthetic modules

                              Name
                              Unk01
                              Type
                              nrps-type1
                              Genes
                              lstE
                              Substrates
                              leucine (evidence: )
                              Integrated Monomers
                              Domains
                              adenylation
                              Annotation changelog

                              Entry version: 4

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2022-10-07
                              Update chemical activity to schema version 2.11
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 3

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2022-09-15
                              Updated bioactivity data
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              2022-09-15
                              Added NRP substrate specificities
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 2

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2019-10-16
                              Migrated from v1.4
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              2019-10-16
                              Updated compound(s) information (NPAtlas curation)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 1

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2015-06-12
                              Submitted
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              Detailed domain annotation
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