BGC0000384: lyngbyatoxin biosynthetic gene cluster from Lyngbya majuscula
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Location: 1 - 17,000 nt. (total: 17,000 nt).
This entry is originally from NCBI GenBank AY588942.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000384
Short description lyngbyatoxin biosynthetic gene cluster from Lyngbya majuscula
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Remarks "Only one condensation domain is present within AAT12283"
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: AY588942.1
Compounds
  • lyngbyatoxin
Species Lyngbya majuscula [taxonomy]
References
Chemical products information
lyngbyatoxin
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C27H39N3O2
Chemical database entries
PubCHEM
ChEBI
ChemSpider
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAT12283.1
 2740 - 10182 (+) LtxA
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  • AAT12284.1
 10185 - 11567 (+) LtxB
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  • AAT12285.1
 11730 - 12902 (+) LtxC
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  • AAT12286.1
 13259 - 13999 (+) LtxD
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NRP-specific information
Subclass N/A
Cyclic? yes
Release type
  • Reductive release
NRP-synthases
Gene Modules
AAT12283.1
Module 2
Specificity: tryptophan
Evidence for specificity:
  • Structure-based inference
  • Homology
Condensation domain type: LCL
Module 1
Specificity: valine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Unknown
Modification domains: Methylation
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: YKUWK3FUALS4CFYG5HJIMS53, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected gene identifiers
  • Updated NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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