LOCUS       BGC0000384             11260 bp    DNA     linear   BCT 20-OCT-2004
DEFINITION  Lyngbya majuscula lyngbyatoxin biosynthetic gene cluster, complete
            sequence.
ACCESSION   BGC0000384
VERSION     BGC0000384
KEYWORDS    .
SOURCE      Lyngbya majuscula
  ORGANISM  Lyngbya majuscula
            Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
            Oscillatoriales; Oscillatoriaceae; Lyngbya.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 13:31:06
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11260
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..7443
                     /NRPS_PKS="Domain: AMP-binding (22-416). E-value: 3.3e-105.
                     Score: 343.8. Matches aSDomain:
                     nrpspksdomains_AAT12283.1_AMP-binding.1"
                     /NRPS_PKS="Domain: nMT (504-728). E-value: 7.1e-108. Score:
                     352.4. Matches aSDomain: nrpspksdomains_AAT12283.1_nMT.1"
                     /NRPS_PKS="Domain: PCP (940-1008). E-value: 6e-25. Score:
                     79.1. Matches aSDomain: nrpspksdomains_AAT12283.1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1023-1321). E-value:
                     2.9e-106. Score: 346.7. Matches aSDomain:
                     nrpspksdomains_AAT12283.1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1491-1896). E-value:
                     1.4e-113. Score: 371.4. Matches aSDomain:
                     nrpspksdomains_AAT12283.1_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2004-2070). E-value: 2e-25. Score:
                     80.6. Matches aSDomain: nrpspksdomains_AAT12283.1_PCP.2"
                     /NRPS_PKS="Domain: TD (2108-2352). E-value: 8.5e-85. Score:
                     275.7. Matches aSDomain: nrpspksdomains_AAT12283.1_TD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     355; E-value: 1.2e-107)"
                     /gene_kind="biosynthetic"
                     /note="NRPS with A-NM-PCP-C-A-PCP-Red domain organization"
                     /product="LtxA"
                     /protein_id="AAT12283.1"
                     /sec_met_domain="Condensation (E-value: 2.3e-69, bitscore:
                     221.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-125, bitscore:
                     406.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.7e-19, bitscore:
                     56.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.3e-09,
                     bitscore: 25.6, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2.1e-72, bitscore:
                     231.3, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIMNQPWSGSRRAIVNSTLPQAFEDRVNRTPNQIAIVFDELHLSY
                     TQLNVKANYLANLLIRSGVEPKTPIAIQIERSIELVVAVLAVLKAGAIYVPLDPRLPLA
                     RVHWILDETRAQTLLTISNSKNLDKIKNIQTTIRVDVHLKKEDPDSPAIDTQPDDLAHI
                     MYTSGSTGHPKGVAITHRAILEFVADRCWKNELQERVLFHSSLGFDISNYELWVPLLRS
                     GQLVMAPSGPLDVSTLKQVIQKQSITSLFLTTSLFNLVTEENPRCLAGVQQVWIGGEQA
                     SVAAIQRMWDACPEITVVNGYGPTETTTYVTLYTIESRPQGNRVPIGRPMENTQVYVLD
                     EELKPVPSGTPGEIYLAGTGLARGYFGQPSLTSTRFLANPFGLPGSRMYRTGDLGVWID
                     SDQLVCLGRSDRQVKIRGIRIEPSEIEAELRNHPEIGEAVVTVREDSPDEKRLIAYLIA
                     KTIESQTQKIQGEQLVAWRQIYDSLYENDTSSPLGSDFSGWHSSYDGCPIPLEQMQEWQ
                     EMTLQEIRGLQPRRILEIGVGTGLLLAQLAPDCESYWGTDFSASLIERLRHRVALEPSL
                     AGRVELRSQSADAIEGLPREHFDTVILNSVIQYFPNPTYLLDVLNKVVDLLVPGGYIFI
                     GDIRNLRLLHCFHTEVQLRRTDLKTLNTLALQAAVEHSVVMEDELLVDPEFFSALGQRR
                     SDIDYVDVRVKRGWHHNEMSQYRYNVILHKCSTTTEPIPTVEWHPIAWGSKFTTLEQLI
                     DYLKQEIPSHLKLVNVPNCRVTPALKAIQQLNAGYDLDVVQDHLFSGDSAACNPEDFYK
                     IGELLDYQVFVTWSNTDIGHLDILFCPQNSQLNNIRVFRTDSPLHNNQGVYDSLLFYMN
                     SPSVSYHAGTFLESVRTHLSERLSQSMIPTAFVILDTFPLTVNGKVDRAALPVPHIGST
                     QNGRAPRNAVEERMCGLFAQILGVTQVTIDDNFFDLGGHSLSVMRLLSRIRSCFDVELA
                     VANVFASPTVAELVKHLTKAEPGRPQLMGMNRPSVVPLSFSQQRLWFIYAFDTSSVIYN
                     VPIAFELAGSINQIAMEMALHDVISRHDSLHTVFQEISGVPRQVLLNPGQFELTITHTS
                     VTELDQKLLDSSQRPFDLSTEIPIRAELFVLGDDRCVLLILLHHITCDGWSFAPLWRDL
                     SEAYATRSQGLIPDWTPLPVQYADYTLWQRRLLGQDIKPDSIITHQLDYWRKNLAELPE
                     LVSLPGDRPRSAVPSFRGALIPFRLSPELHHGAINLAQQQGTSLFMVLHAVLAVLLTRL
                     GAGTDLPIGTPVANRTDDALEDLVGFFVNLLVLRTDTSGDPSFSDLLARIRDLDIAAYA
                     HQDIPFELLVEKLRPVRSITHHPFFEILLALQSAPENQLKLSGVKISHKQVHLGTCRFD
                     LVMNLDEHRHQDGTLLGIDGLVEYRTDLYDRKTIQTFIDRFLRLLTGAIADPQQRISRL
                     NLLSPEEHHQLLIEWNDTDHSISPRPFPDLFEAQVAQTPTANALVFGALHLSYQELNAR
                     ANQLAHQLIYQGIGPGQVIAIDVPRSPEWVIAVLAVLKAGAAYLPLDPSYPASRIIYML
                     EDVQPCLLITTTNSLISNPKLNIPKLQLDSFPWEASLNVTSEKQDYGLQANIEDNRGTQ
                     PLHVSDPAYIIYTSGSTGKPKGVVVTHAGISSMVATQIKYFEVTPESRILQFSSLSFDG
                     VVWELCSALLTGATLVMAPSERVQPGPELIQLIGDYHVTHAVLPPAVLMVLSPDNIPSL
                     THLIVSGEAASGELVKRWSVGRCLINGYGPTETTVCATLSSPLSGNGIPPIGRAVINVQ
                     CYVLDDQLQLLPPGAIGELYISGPGLARGYLNQPQLTAERFLANPFRDIGSRMYRTGDL
                     VRWRNHGELEFVGRADNQVKIRGFRVELGEVETALTNCPPVSDALAMVREDRPGEKFLV
                     AYVVGQDSMDTDALRAQLVNDLPPYLIPGAIVTLKKFPLTVNGKIDRKALPVPKFTSIA
                     EGRVPKTPTQIGLCTLFAELLGVDQVTIDDPFFALGGHSLLATQLVSQIRQRFGISLPV
                     QTVFERQTVADLAIVVDREAPIVSTSIDLAAEVVLNPQIAPYQSRPVELDRNTHPASVL
                     LTGATGFLGAYLLYELLKQTDANVFCLVRSNHSEAAYQRIHSTLKFYQLWSESWRSRII
                     PVCGDLSQPSLGLSAEEFSKLTELIDAIYHNGAQVSAIEPYTYLKPTNVLGTSELLDFA
                     ARCRVKPLHFVSTAAVAVSSKGNPDIIYENFRLGADSVLPSGYVSSKWVAEELVWVASD
                     RGLPVTVHRPGRISGDTTTGIGNTDDTFWQIVRAIVVLGVVPDIVYQDDAGIDLMPVDR
                     VASAIVHLSRHKQSISKVHHLTCPTIVKLDVVFNELSKLGYQLTTVSYSEWVKQLEQYV
                     DQAPGGHSLASATVLSRTLPKLIELSQICFDQSNTLTGLAEAPFKFPCIDRHLVRGYLT
                     YFINSKFFPQITYTGK"
     protocluster    1..11260
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[8990:10163]"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8991..10163
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     protocluster    1..11260
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:7443]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      1..7443
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
     cand_cluster    1..11260
                     /SMILES="NC(C(C)C)C(=O)NC(CC1=CNc2c1cccc2)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="neighbouring"
                     /product="indole"
                     /product="NRPS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..11260
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000384"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..11260
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="indole"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     aSDomain        67..1248
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAT12283.1_AMP-binding.1"
                     /evalue="3.30E-105"
                     /label="AAT12283.1_AMP-binding.1"
                     /locus_tag="AAT12283.1"
                     /protein_end="416"
                     /protein_start="22"
                     /score="343.8"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FEDRVNRTPNQIAIVFDELHLSYTQLNVKANYLANLLIRSGVEPK
                     TPIAIQIERSIELVVAVLAVLKAGAIYVPLDPRLPLARVHWILDETRAQTLLTISNSKN
                     LDKIKNIQTTIRVDVHLKKEDPDSPAIDTQPDDLAHIMYTSGSTGHPKGVAITHRAILE
                     FVADRCWKNELQERVLFHSSLGFDISNYELWVPLLRSGQLVMAPSGPLDVSTLKQVIQK
                     QSITSLFLTTSLFNLVTEENPRCLAGVQQVWIGGEQASVAAIQRMWDACPEITVVNGYG
                     PTETTTYVTLYTIESRPQGNRVPIGRPMENTQVYVLDEELKPVPSGTPGEIYLAGTGLA
                     RGYFGQPSLTSTRFLANPFGLPGSRMYRTGDLGVWIDSDQLVCLGRSDRQVKIR"
     aSModule        67..3024
                     /complete
                     /domains="nrpspksdomains_AAT12283.1_AMP-binding.1"
                     /domains="nrpspksdomains_AAT12283.1_nMT.1"
                     /domains="nrpspksdomains_AAT12283.1_PCP.1"
                     /locus_tags="AAT12283.1"
                     /monomer_pairings="Val -> NMe-Val"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       253..294
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0001"
                     /evalue="1.60E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="AAT12283.1"
                     /protein_end="98"
                     /protein_start="84"
                     /score="18.0"
                     /tool="antismash"
                     /translation="LAVLKAGAIYVPLD"
     CDS_motif       481..540
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0002"
                     /evalue="6.50E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="AAT12283.1"
                     /protein_end="180"
                     /protein_start="160"
                     /score="24.9"
                     /tool="antismash"
                     /translation="AHIMYTSGSTGHPKGVAITH"
     CDS_motif       904..927
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0003"
                     /evalue="4.20E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="AAT12283.1"
                     /protein_end="309"
                     /protein_start="301"
                     /score="4.2"
                     /tool="antismash"
                     /translation="YGPTETTT"
     CDS_motif       1039..1128
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0004"
                     /evalue="8.50E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="AAT12283.1"
                     /protein_end="376"
                     /protein_start="346"
                     /score="40.5"
                     /tool="antismash"
                     /translation="PSGTPGEIYLAGTGLARGYFGQPSLTSTRF"
     CDS_motif       1213..1278
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0005"
                     /evalue="5.30E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="AAT12283.1"
                     /protein_end="426"
                     /protein_start="404"
                     /score="31.4"
                     /tool="antismash"
                     /translation="CLGRSDRQVKIRGIRIEPSEIE"
     aSDomain        1513..2184
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAT12283.1_nMT.1"
                     /domain_subtypes="nMT"
                     /evalue="7.10E-108"
                     /label="AAT12283.1_nMT.1"
                     /locus_tag="AAT12283.1"
                     /protein_end="728"
                     /protein_start="504"
                     /score="352.4"
                     /tool="antismash"
                     /translation="GCPIPLEQMQEWQEMTLQEIRGLQPRRILEIGVGTGLLLAQLAPD
                     CESYWGTDFSASLIERLRHRVALEPSLAGRVELRSQSADAIEGLPREHFDTVILNSVIQ
                     YFPNPTYLLDVLNKVVDLLVPGGYIFIGDIRNLRLLHCFHTEVQLRRTDLKTLNTLALQ
                     AAVEHSVVMEDELLVDPEFFSALGQRRSDIDYVDVRVKRGWHHNEMSQYRYNVILHKCS
                     TT"
     CDS_motif       2743..2769
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0006"
                     /evalue="5.80E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="AAT12283.1"
                     /protein_end="923"
                     /protein_start="914"
                     /score="3.6"
                     /tool="antismash"
                     /translation="GKVDRAALP"
     CDS_motif       2782..2844
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0007"
                     /evalue="1.30E+01"
                     /label="C5_DCL_263-294"
                     /locus_tag="AAT12283.1"
                     /protein_end="948"
                     /protein_start="927"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="GSTQNGRAPRNAVEERMCGLF"
     aSDomain        2821..3024
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAT12283.1_PCP.1"
                     /evalue="6.00E-25"
                     /label="AAT12283.1_PCP.1"
                     /locus_tag="AAT12283.1"
                     /protein_end="1008"
                     /protein_start="940"
                     /score="79.1"
                     /tool="antismash"
                     /translation="EERMCGLFAQILGVTQVTIDDNFFDLGGHSLSVMRLLSRIRSCFD
                     VELAVANVFASPTVAELVKHLTK"
     CDS_motif       2884..2913
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0008"
                     /evalue="5.00E-02"
                     /label="PCP_mC"
                     /locus_tag="AAT12283.1"
                     /protein_end="971"
                     /protein_start="961"
                     /score="7.4"
                     /tool="antismash"
                     /translation="NFFDLGGHSL"
     aSDomain        3070..3963
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAT12283.1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.90E-106"
                     /label="AAT12283.1_Condensation_LCL.1"
                     /locus_tag="AAT12283.1"
                     /protein_end="1321"
                     /protein_start="1023"
                     /score="346.7"
                     /tool="antismash"
                     /translation="VVPLSFSQQRLWFIYAFDTSSVIYNVPIAFELAGSINQIAMEMAL
                     HDVISRHDSLHTVFQEISGVPRQVLLNPGQFELTITHTSVTELDQKLLDSSQRPFDLST
                     EIPIRAELFVLGDDRCVLLILLHHITCDGWSFAPLWRDLSEAYATRSQGLIPDWTPLPV
                     QYADYTLWQRRLLGQDIKPDSIITHQLDYWRKNLAELPELVSLPGDRPRSAVPSFRGAL
                     IPFRLSPELHHGAINLAQQQGTSLFMVLHAVLAVLLTRLGAGTDLPIGTPVANRTDDAL
                     EDLVGFFVNLLVLRTDT"
     aSModule        3070..7056
                     /complete
                     /domains="nrpspksdomains_AAT12283.1_Condensation_LCL.1"
                     /domains="nrpspksdomains_AAT12283.1_AMP-binding.2"
                     /domains="nrpspksdomains_AAT12283.1_PCP.2"
                     /domains="nrpspksdomains_AAT12283.1_TD.1"
                     /final_module
                     /locus_tags="AAT12283.1"
                     /monomer_pairings="Trp -> Trp"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3136..3246
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0009"
                     /evalue="1.80E-10"
                     /label="C2_LCL_024-062"
                     /locus_tag="AAT12283.1"
                     /protein_end="1082"
                     /protein_start="1045"
                     /score="33.2"
                     /tool="antismash"
                     /translation="IYNVPIAFELAGSINQIAMEMALHDVISRHDSLHTVF"
     CDS_motif       3445..3510
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0010"
                     /evalue="5.20E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="AAT12283.1"
                     /protein_end="1170"
                     /protein_start="1148"
                     /score="28.6"
                     /tool="antismash"
                     /translation="LHHITCDGWSFAPLWRDLSEAY"
     CDS_motif       3559..3597
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0011"
                     /evalue="5.80E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="AAT12283.1"
                     /protein_end="1199"
                     /protein_start="1186"
                     /score="15.7"
                     /tool="antismash"
                     /translation="QYADYTLWQRRLL"
     CDS_motif       3865..3954
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0012"
                     /evalue="1.00E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="AAT12283.1"
                     /protein_end="1318"
                     /protein_start="1288"
                     /score="46.8"
                     /tool="antismash"
                     /translation="DLPIGTPVANRTDDALEDLVGFFVNLLVLR"
     CDS_motif       4015..4122
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0013"
                     /evalue="2.30E-15"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="AAT12283.1"
                     /protein_end="1374"
                     /protein_start="1338"
                     /score="48.9"
                     /tool="antismash"
                     /translation="IAAYAHQDIPFELLVEKLRPVRSITHHPFFEILLAL"
     aSDomain        4474..5688
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAT12283.1_AMP-binding.2"
                     /evalue="1.40E-113"
                     /label="AAT12283.1_AMP-binding.2"
                     /locus_tag="AAT12283.1"
                     /protein_end="1896"
                     /protein_start="1491"
                     /score="371.4"
                     /specificity="substrate consensus: Trp"
                     /tool="antismash"
                     /translation="FEAQVAQTPTANALVFGALHLSYQELNARANQLAHQLIYQGIGPG
                     QVIAIDVPRSPEWVIAVLAVLKAGAAYLPLDPSYPASRIIYMLEDVQPCLLITTTNSLI
                     SNPKLNIPKLQLDSFPWEASLNVTSEKQDYGLQANIEDNRGTQPLHVSDPAYIIYTSGS
                     TGKPKGVVVTHAGISSMVATQIKYFEVTPESRILQFSSLSFDGVVWELCSALLTGATLV
                     MAPSERVQPGPELIQLIGDYHVTHAVLPPAVLMVLSPDNIPSLTHLIVSGEAASGELVK
                     RWSVGRCLINGYGPTETTVCATLSSPLSGNGIPPIGRAVINVQCYVLDDQLQLLPPGAI
                     GELYISGPGLARGYLNQPQLTAERFLANPFRDIGSRMYRTGDLVRWRNHGELEFVGRAD
                     NQVKIR"
     CDS_motif       4660..4701
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0014"
                     /evalue="1.40E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="AAT12283.1"
                     /protein_end="1567"
                     /protein_start="1553"
                     /score="18.2"
                     /tool="antismash"
                     /translation="LAVLKAGAAYLPLD"
     CDS_motif       4936..4995
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0015"
                     /evalue="9.90E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="AAT12283.1"
                     /protein_end="1665"
                     /protein_start="1645"
                     /score="33.4"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVVVTH"
     CDS_motif       5350..5376
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0016"
                     /evalue="2.00E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="AAT12283.1"
                     /protein_end="1792"
                     /protein_start="1783"
                     /score="7.9"
                     /tool="antismash"
                     /translation="YGPTETTVC"
     CDS_motif       5479..5568
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0017"
                     /evalue="1.00E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="AAT12283.1"
                     /protein_end="1856"
                     /protein_start="1826"
                     /score="59.3"
                     /tool="antismash"
                     /translation="PPGAIGELYISGPGLARGYLNQPQLTAERF"
     CDS_motif       5653..5718
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0018"
                     /evalue="7.50E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="AAT12283.1"
                     /protein_end="1906"
                     /protein_start="1884"
                     /score="37.2"
                     /tool="antismash"
                     /translation="FVGRADNQVKIRGFRVELGEVE"
     CDS_motif       5926..5952
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0019"
                     /evalue="1.50E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="AAT12283.1"
                     /protein_end="1984"
                     /protein_start="1975"
                     /score="5.2"
                     /tool="antismash"
                     /translation="GKIDRKALP"
     aSDomain        6013..6210
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAT12283.1_PCP.2"
                     /evalue="2.00E-25"
                     /label="AAT12283.1_PCP.2"
                     /locus_tag="AAT12283.1"
                     /protein_end="2070"
                     /protein_start="2004"
                     /score="80.6"
                     /tool="antismash"
                     /translation="LCTLFAELLGVDQVTIDDPFFALGGHSLLATQLVSQIRQRFGISL
                     PVQTVFERQTVADLAIVVDRE"
     CDS_motif       6070..6096
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0020"
                     /evalue="1.00E-01"
                     /label="PCP_mC"
                     /locus_tag="AAT12283.1"
                     /protein_end="2032"
                     /protein_start="2023"
                     /score="6.5"
                     /tool="antismash"
                     /translation="FFALGGHSL"
     aSDomain        6325..7056
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAT12283.1_TD.1"
                     /evalue="8.50E-85"
                     /label="AAT12283.1_TD.1"
                     /locus_tag="AAT12283.1"
                     /protein_end="2352"
                     /protein_start="2108"
                     /score="275.7"
                     /tool="antismash"
                     /translation="VLLTGATGFLGAYLLYELLKQTDANVFCLVRSNHSEAAYQRIHST
                     LKFYQLWSESWRSRIIPVCGDLSQPSLGLSAEEFSKLTELIDAIYHNGAQVSAIEPYTY
                     LKPTNVLGTSELLDFAARCRVKPLHFVSTAAVAVSSKGNPDIIYENFRLGADSVLPSGY
                     VSSKWVAEELVWVASDRGLPVTVHRPGRISGDTTTGIGNTDDTFWQIVRAIVVLGVVPD
                     IVYQDDAGIDLMPVDRVASAIV"
     CDS_motif       7222..7242
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0021"
                     /evalue="4.10E+01"
                     /label="PCP_mC"
                     /locus_tag="AAT12283.1"
                     /protein_end="2414"
                     /protein_start="2407"
                     /score="-1.1"
                     /tool="antismash"
                     /translation="APGGHSL"
     CDS             7446..8828
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1009:mbtH-like protein (Score: 85.8; E-value:
                     2.1e-26)"
                     /gene_kind="biosynthetic-additional"
                     /note="P450 monooxygenase"
                     /product="LtxB"
                     /protein_id="AAT12284.1"
                     /sec_met_domain="p450 (E-value: 8.1e-28, bitscore: 85.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNPFADPSRDYWVLCNAEGQYSLWPTSLEIPEGWQTAFGPESWQ
                     NCLDNVEKNWTDMRPLSLLGQRKCPVPYPFREYVALNMDPIYASLQQRDEMLRISVPYG
                     DDAWLASSYKHVKCVIQDTRFSRETTKYDEARLTPIPIRTSVLGMDPPDHTRLREALAA
                     ALTPSHVEQMKPWITSMTEQLIDDFVAQGPPADLVEQFALPFTGHITCELMGIPLEDRP
                     QFKAWCDGFSSTSSLTKEEVEVRMQAMYTYITELVGRRRESPSDDIISKLLQPEDKRLE
                     LSEIELIDLATILLLAGYDSTAMELANAIFVLLTHPEQTQLIREQPKLMPQAVQELLRY
                     IPIDAHVTFARYATEDVQVGNTLVRTGDAILASFPSANHDPAIFEDPHTFNIMRPRKPN
                     FGLGTGIHSCAGKLLAVVELEIALSVLIRRLPTLRLAIPAEEVPWQPGSLLRSTSKLPA
                     EW"
     CDS             8991..10163
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /note="prenyltransferase"
                     /product="LtxC"
                     /protein_id="AAT12285.1"
                     /sec_met_domain="indole_PTase (E-value: 2e-100, bitscore:
                     324.3, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSKIAVSEYASDSFGKADTRAYDDLPIFASNYYSREASYIDIAC
                     DKLHRACDGLAFPAERRDTIVAFLRKLCTPWGNALASAPQHFSNVSVEGMPFELSLAWS
                     NGRGHELRMSFEVLHSPHSLSNNLEAARRFVRELPSIPELAPDISIENFLLIEDLVTAS
                     EPTDFITPMGQGIAWLSDRPNPVMKTYLNLNIAGFESGPERTKEAMTRLGAGSAWQSLC
                     SYLTSLGVSVVPLFLALDLAHSDHPRLKIYLPHTGVDAGMIDKQAEIAQTHVNGKFKEA
                     LLEITGHTTPDWRKVPVTCYTLVPGQDRPVAATLYVPLNPNIENDAVAQERVCAFSQSQ
                     GVDPSPYESLLKAISDKPLSQLSTHNFVAYRPGKDPRFSVYLAPGVYKRS"
     CDS             10520..11260
                     /NRPS_PKS="Domain: PKS_KR (7-167). E-value: 3e-16. Score:
                     51.7. Matches aSDomain: nrpspksdomains_AAT12286.1_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     237.3; E-value: 3e-72)"
                     /gene_kind="biosynthetic-additional"
                     /note="reductase/oxidase"
                     /product="LtxD"
                     /protein_id="AAT12286.1"
                     /sec_met_domain="adh_short (E-value: 2.6e-40, bitscore:
                     126.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.4e-37, bitscore:
                     118.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKLQGKVAIITGGSRGIGRAIAERLAQDGATIMLTYLRNKALAE
                     AVVAQIETQGGQARAMAVDLAQPADIERLFEMTEATWQRLDILVNSAAELQTGSIESFS
                     IHDWQRVFAVNSTAPFLTIQQAARRLSAHGRIVNVSTINTVLAEPGIAAYAASKGSLEQ
                     LTRVAAWELADRGITVNSVSPGPTDTDLLRTGNPPEVLEQAIAMTPLGRLGQPKDIADV
                     VAFLVGNDGRWITGQNLRVTGGLI"
     aSDomain        10541..11020
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAT12286.1_PKS_KR.1"
                     /evalue="3.00E-16"
                     /label="AAT12286.1_PKS_KR.1"
                     /locus_tag="AAT12286.1"
                     /protein_end="167"
                     /protein_start="7"
                     /score="51.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAIITGGSRGIGRAIAERLAQDGATIMLTYLRNKALAEAVVAQIE
                     TQGGQARAMAVDLAQPADIERLFEMTEATWQRLDILVNSAAELQTGSIESFSIHDWQRV
                     FAVNSTAPFLTIQQAARRLSAHGRIVNVSTINTVLAEPGIAAYAASKGSLEQLTRV"
     CDS_motif       10547..10615
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12286.1_0001"
                     /evalue="3.00E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="AAT12286.1"
                     /protein_end="32"
                     /protein_start="9"
                     /score="23.1"
                     /tool="antismash"
                     /translation="IITGGSRGIGRAIAERLAQDGAT"
ORIGIN
        1 atgattatga atcaaccttg gagtggaagt aggcgggcga tagtaaattc gactttaccc
       61 caagcatttg aggatcgagt taaccgaact ccaaatcaga ttgccatcgt ttttgacgaa
      121 cttcacctgt cctacaccca gcttaatgtt aaagctaatt acttagctaa tctcttaatt
      181 cgttctggtg ttgaaccaaa aactcctatt gccattcaga tagagcgttc gattgagtta
      241 gtggttgctg tccttgctgt gcttaaagca ggtgccatct atgttcctct agacccccgt
      301 ctacctctag cgcgagttca ttggatatta gatgaaacaa gggcacaaac attactgact
      361 ataagtaatt caaagaatct agacaagatc aaaaatattc aaacaacaat tagagtagat
      421 gtccatttaa aaaaggaaga tccagatagt cctgctatag atacgcaacc cgatgatctt
      481 gctcatatta tgtacacctc aggctcgaca gggcatccta aaggggtcgc tattacccat
      541 cgagccattt tagaattcgt tgcggatcgg tgttggaaaa atgaacttca ggagcgagtc
      601 ctatttcaca gttctctagg ctttgatatc tcaaattatg aactgtgggt gcctctttta
      661 cgatctggac agttagttat ggccccttct ggacccttgg atgtttctac tcttaaacaa
      721 gttatccaga agcaatctat tacatcttta ttcttaacta cttcattatt caatctagtt
      781 actgaggaaa atcccagatg ccttgcaggt gttcaacaag tatggattgg aggggaacaa
      841 gcttcagtag ctgctattca gcggatgtgg gatgcttgcc ctgagattac tgtggtcaat
      901 ggttatggtc ctacagagac caccacatat gtcacccttt atactattga aagtcgccct
      961 cagggcaatc gagtcccgat cggtaggccg atggaaaata cccaggtcta tgtacttgac
     1021 gaggaactaa aacccgttcc ttccggtaca ccaggagaaa tctatctggc aggaacaggt
     1081 cttgcacgag gctactttgg tcaaccaagt ttaacatcca cacggttcct tgctaatccc
     1141 tttgggctac caggatcgcg gatgtatcgc actggtgatt taggagtgtg gattgactcg
     1201 gatcagcttg tctgtcttgg tcgctctgat cgacaagtta agatccgtgg cattcgcatt
     1261 gaacctagcg aaatagaggc agaactccgc aatcatccag agattggtga agcagtcgtt
     1321 acagttcgcg aggattctcc agatgaaaag cgcttgattg cctacctaat cgccaaaacg
     1381 attgaatcac aaacgcagaa aattcagggg gaacaactgg tagcttggcg tcaaatctat
     1441 gactcgctct acgaaaatga tacttcttct cctttgggat cggatttttc aggttggcac
     1501 agtagctatg acggttgtcc tattccctta gaacagatgc aggaatggca ggagatgaca
     1561 ctgcaggaga ttcgtgggct tcagcctcgg cgaatcttgg aaattggagt tggtactggt
     1621 ctgttgctag ctcaattagc tccagactgt gagtcttatt ggggaactga tttctcggca
     1681 tctttaattg aaaggttacg tcatcgggtt gcccttgagc catccctagc aggtcgtgta
     1741 gagcttcgct ctcagagtgc tgatgcgatc gaagggttac ctcgggagca tttcgatact
     1801 gtaattctca attctgtaat tcagtatttt cctaatccta cctatttgct tgatgttctg
     1861 aacaaggtgg tagatttgct tgttccaggt ggttatattt tcattggtga cattcggaac
     1921 ttgcgtcttt tgcactgttt tcacactgaa gttcaactgc ggcgtactga cctcaaaact
     1981 ctcaacaccc tcgcgttaca agcagctgtt gaacatagtg tagtgatgga agatgaactg
     2041 ttagtcgatc ctgagttttt ttcagcttta ggtcaaagac gatcggacat tgactatgta
     2101 gatgtgcgag ttaaaagggg ttggcaccat aatgaaatgt ctcagtatcg ttacaacgtt
     2161 atcctccaca aatgctcgac cacaacagaa cctataccta ctgttgagtg gcatccgatc
     2221 gcttggggat caaaatttac aacccttgaa cagttgattg attatcttaa acaggagata
     2281 ccatcccacc taaaattagt caatgtgccc aactgtcgcg ttactcctgc tcttaaagca
     2341 atacaacagt tgaatgcggg ttacgatctt gatgttgtgc aagatcatct attctctgga
     2401 gactctgctg cttgcaaccc agaagacttc tataagattg gagagttatt ggattatcaa
     2461 gtttttgtaa cttggtctaa tacagacata ggccatcttg acatcctgtt ttgtccccag
     2521 aatagtcagt tgaataacat cagagtcttc aggaccgata gtcctcttca taataatcag
     2581 ggggtatacg attccttatt gttttacatg aactctccct ctgtctcata ccatgcagga
     2641 acatttctag aatcagtgcg gactcatctg agtgaaaggt tatctcagtc gatgataccc
     2701 actgcctttg tcattctgga tacttttccg ttgactgtaa atggcaaagt cgatcgtgct
     2761 gctttacctg ttccccatat tggttccact cagaatggac gcgcccccag aaatgctgtt
     2821 gaagagcgta tgtgtggctt gttcgctcaa attctgggcg ttactcaagt tacaattgat
     2881 gataattttt ttgatcttgg tgggcattct ttatctgtga tgcggttatt aagccgtatc
     2941 cgctcatgct ttgatgtgga actagctgtt gccaatgttt ttgcttcacc aacagtcgct
     3001 gaactggtca aacatctaac caaagcagaa ccagggcgac ctcaactcat gggtatgaac
     3061 cgccccagtg ttgtaccatt gtctttttct caacaacgtc tgtggtttat ctatgctttt
     3121 gatacttcta gtgtaattta taatgtcccc atcgcttttg agctggctgg ctccatcaat
     3181 caaattgcga tggagatggc tttacatgac gtcatctcca gacatgatag cttacatact
     3241 gtctttcagg aaattagcgg tgtaccacgc caggttctat tgaatccggg tcagtttgaa
     3301 ttgactatca ctcacacttc tgtaacagaa ctggatcaga aacttctgga cagtagtcag
     3361 cgaccttttg acctcagtac tgaaattcca atccgagcag aactatttgt cctgggagac
     3421 gatcgatgtg tcctcctcat tcttctacac catattacct gcgatggatg gtcttttgcc
     3481 cccttatggc gcgatctttc ggaggcttat gccacccgtt cccagggtct catccctgac
     3541 tggacaccgc tacctgtaca gtatgcagat tataccctat ggcaaagacg actccttggc
     3601 caagacatta agccagatag tattattact catcaacttg actattggcg caaaaaccta
     3661 gcggagctac ctgaacttgt atcccttcct ggagatcgcc cccgatctgc tgtcccttcc
     3721 tttagaggtg ctcttattcc ctttcggttg agccctgaac tccatcatgg ggcgatcaat
     3781 ctggctcaac aacaaggaac aagtctattc atggtgttgc atgctgttct tgctgtcctt
     3841 ttaactcgtc tgggtgcagg aaccgatctg cccattggaa cccctgtggc taatcgcaca
     3901 gatgatgcac ttgaagattt ggttgggttc tttgttaact tgctcgttct acgaacagat
     3961 acctctggcg atccaagttt ctccgatctc ttagcccgaa tcagagacct agatattgct
     4021 gcttatgccc atcaagatat tccctttgag ttgttggtcg agaaacttcg acccgtgaga
     4081 tccataactc atcacccctt ctttgaaatt ttgctagccc tacagagtgc accagagaat
     4141 cagttaaagc tgtctggggt taagataagt cacaaacagg ttcatttggg aacctgtcgt
     4201 tttgatttgg tgatgaatct tgatgaacac cgacatcagg acgggacact cctgggaatt
     4261 gatggcctgg ttgagtatcg tactgatttg tacgatcgta agacgattca gacttttatc
     4321 gatcgcttct tgagactctt gaccggagcc attgctgacc ctcaacagcg gattagtaga
     4381 ctcaacctct tgagtcctga agaacaccat caactcttga tcgaatggaa tgatacggac
     4441 catagcatca gtccacgacc ttttccagac ctgtttgaag cccaagtagc ccaaactcct
     4501 acagctaatg cacttgtatt tggggctttg catctgtcct atcaagaact caatgctcgt
     4561 gctaaccaac tagcccatca actgatctat caaggcatag gtccaggcca agtcatcgcg
     4621 atcgatgttc cacgatcgcc cgaatgggtc attgctgttt tagctgtact caaagcaggt
     4681 gcagcctact tacccctaga cccctcttac ccagcctctc gcattatcta tatgctggag
     4741 gatgtccaac cctgcctgtt aatcaccaca actaatagtc tcattagtaa tccaaagctc
     4801 aatattccaa aactacaact cgatagcttt ccctgggagg cttcccttaa cgtcaccagt
     4861 gaaaaacagg attatggatt acaggctaat atagaggaca atcggggcac tcagccactg
     4921 catgtgtccg atccagccta tataatttac acttcaggct ctacaggaaa acccaaagga
     4981 gttgtggtaa cccatgctgg aatttcgagt atggtcgcaa cacaaatcaa gtactttgag
     5041 gtaactcctg agagtcgtat cctccagttc tcttctttaa gttttgacgg cgtagtttgg
     5101 gaactgtgca gtgccctgtt aactggtgcc accttggtga tggctccctc agaacgggtg
     5161 caaccaggtc cggaactgat ccaattgatc ggagactatc acgttaccca tgctgtcttg
     5221 ccaccagcag tattaatggt gctatcacca gataatatac cctccttgac ccatctcatt
     5281 gtctcaggcg aggctgcctc aggtgaatta gtaaaacggt ggtctgttgg gcgctgcttg
     5341 attaatggtt atggtcccac tgaaactacc gtctgtgcta ccttgagttc tcccctatct
     5401 ggtaatggga taccccccat tggcagagcg gttatcaacg ttcaatgtta tgtccttgat
     5461 gatcaattgc aacttcttcc ccctggagcg atcggtgaac tttacatatc tggccctggc
     5521 ctagcccgtg gatatctgaa ccagcctcag cttacggcag agcgattctt ggcaaatccc
     5581 tttagggaca tcggaagccg tatgtatcgg actggagatt tagttcgttg gcgaaaccac
     5641 ggtgagcttg agtttgtagg cagagctgat aatcaggtca agattcgggg ttttcgtgtt
     5701 gaattgggtg aagtagaaac tgcccttacc aattgtcccc cagtgtcaga tgccctcgct
     5761 atggttcgtg aggatcgacc gggcgaaaaa ttcctagtgg cctatgtggt tggtcaggat
     5821 tctatggata ctgatgctct gcgtgcccag ctcgttaatg atttacctcc atacttgatc
     5881 cctggcgcta ttgtcacttt gaagaaattt cccctgacag tgaacggtaa aatagatcgt
     5941 aaggctctcc cagttccaaa gttcacttct attgctgaag ggcgtgttcc caaaactcct
     6001 acccagattg gtttatgtac tctgtttgca gaactgttgg gtgttgatca agtcacgatc
     6061 gacgatccgt tttttgccct tggaggtcac tcgttgctag ccacacaatt agtgagtcag
     6121 attcggcagc gttttgggat aagtttgcca gtgcaaactg tattcgagcg acagacggtg
     6181 gctgacctgg caatagtagt agatcgggaa gcacctatag tttctacttc cattgacctt
     6241 gctgctgaag ttgttcttaa tccgcagatt gctccctacc agagtcgtcc agttgaactc
     6301 gataggaata ctcacccagc ctcggtgtta ttaaccggag caactggctt tttgggggca
     6361 tatttgcttt atgaacttct gaagcagact gatgctaatg tattttgctt ggtgcgctcc
     6421 aaccactctg aagctgccta tcaacgcatc cattcgactc tcaaatttta tcaattatgg
     6481 tctgaatctt ggagatcgcg aatcattcca gtgtgtggcg atctctccca gccaagttta
     6541 ggcttatccg ctgaggaatt cagcaagctc acagaattaa ttgatgctat ctatcacaat
     6601 ggagcccagg tcagtgctat tgaaccctat acatacctta aaccaacaaa tgtattgggg
     6661 acatcagagt tactggactt tgctgcgcga tgccgcgtga agccattgca ctttgtttca
     6721 acagctgcag tggctgtaag ttctaaaggt aatcctgata taatttatga gaattttaga
     6781 cttggagcag attctgtatt acccagtgga tatgtctcta gtaaatgggt cgctgaagag
     6841 ttagtgtggg tggcatcaga ccgtggcctc cccgttactg tccaccgccc aggccgaatt
     6901 agtggtgata ccactactgg tattgggaat actgatgata cattctggca aatagtcagg
     6961 gcaatagttg ttctaggggt tgtcccagat attgtttatc aagatgatgc cgggatcgat
     7021 ttaatgccag tcgatcgcgt tgcaagtgca attgtccatc tatcccgtca taaacaatcc
     7081 ataagcaagg tgcatcacct cacctgtcct acaatagtca agctagatgt agtgtttaat
     7141 gaactctcta aattgggcta ccagttaacc acggtatcct actctgaatg ggttaagcaa
     7201 ttagaacagt acgtcgatca agccccaggg gggcactccc tagcatcagc taccgtcctt
     7261 agtcgtacat tacccaagct catagaactc agtcaaatct gcttcgacca aagcaacacc
     7321 ttaacgggtt tagctgaagc accatttaag tttccttgta ttgatcgtca tcttgtccgt
     7381 ggatacctca cttatttcat caactctaaa ttcttccctc aaataactta tacaggaaag
     7441 taaacatgac aaatcctttt gcagaccctt caagggacta ctgggtacta tgcaatgccg
     7501 aaggtcaata ttccctatgg cccacttccc ttgaaattcc tgaaggctgg caaaccgctt
     7561 tcggccccga gagttggcaa aattgccttg acaacgttga gaaaaactgg actgacatgc
     7621 gccccctcag tctgttaggt caacggaagt gtcctgtgcc ttaccccttt cgagaatatg
     7681 ttgcccttaa catggatcca atctacgcca gtctgcaaca acgggatgaa atgctacgaa
     7741 ttagtgttcc ctatggggat gatgcctggt tagcctccag ttacaaacat gtcaagtgtg
     7801 ttatacaaga tacacgtttt agccgagaaa caactaagta tgatgaggct cgcttaacac
     7861 caataccgat ccgcacgagt gtattgggga tggatcctcc agaccataca cgattacgtg
     7921 aggctttagc cgcagctctc actcctagtc atgttgagca aatgaagcct tggataacca
     7981 gcatgacaga acaactgatc gatgactttg tggcccaagg tccccctgcc gatctagtcg
     8041 agcaatttgc tttgccattt actggacaca taacttgcga actcatggga attccgctag
     8101 aagatcgtcc ccaattcaaa gcatggtgtg atggattttc ctccacttcg tctctcacca
     8161 aagaggaagt agaagttcgt atgcaggcaa tgtataccta tattactgag cttgtggggc
     8221 gacgacggga atctccaagt gatgacatta ttagtaaatt actgcaacct gaggataagc
     8281 gcctggagct atcagaaatt gaactgattg acctagccac gatcttatta cttgcaggat
     8341 atgactcaac agctatggaa cttgcaaatg cgatttttgt acttttaacc cacccagaac
     8401 agacccaact catccgagaa caacccaagc tgatgcccca agctgtgcaa gaattgctcc
     8461 gctatattcc cattgacgcc catgttactt ttgctcgcta tgccactgag gacgttcagg
     8521 ttggtaatac gcttgttcgc actggtgatg caattttggc gtctttcccc tctgccaatc
     8581 acgatcctgc aatatttgaa gatcctcaca cattcaatat catgcgacct cgcaaaccaa
     8641 actttggctt aggaactggt atacacagtt gtgctggtaa gctcctggct gttgtggagt
     8701 tggagattgc actatctgtc ttgattagac gtctgcctac tttacgttta gctattccag
     8761 ctgaagaagt gccatggcaa ccaggctctc tgttgcgcag tacttcaaag ttacctgctg
     8821 agtggtaact aaaaaagtag taatctccat ggctttaggc cggaaaggat gtcatttcag
     8881 ttatcagtta tcagtacctc ctgctgaagc aggaggcttg agacccaaat ttttcggtca
     8941 atgattccat tttatctgtc ctttatctct gtaaattgga gtgttttctt atgaattcaa
     9001 agatcgctgt ttctgaatac gccagtgata gttttggtaa ggctgatact cgggcctatg
     9061 atgacctgcc aattttcgct tcaaattatt actcacgaga agcgagttat attgatattg
     9121 cctgtgacaa actacatcga gcgtgtgatg gattggcctt cccagcagag cgtagggata
     9181 ccatagttgc cttccttcgt aaactctgta ccccatgggg taacgcttta gctagtgctc
     9241 cgcagcattt ttctaatgta tctgttgagg gaatgccctt tgaactatcc ctggcctgga
     9301 gcaatggtcg aggtcatgaa ttacggatgt cttttgaagt cctccatagc ccccatagct
     9361 tgagtaataa tcttgaagct gcccgtcgat ttgtgcgaga gctgcccagt attcctgaat
     9421 tggctccgga tatctccatt gagaactttc ttctaattga agatttagtg actgcttccg
     9481 agccaacaga ttttattact cccatgggtc agggtattgc ttggttatct gacagaccaa
     9541 atcctgtgat gaaaacctac cttaatctca atattgctgg ttttgaatct gggcctgagc
     9601 gaactaagga agccatgact aggttaggtg caggttctgc ctggcaatca ctttgttcct
     9661 atctcactag cctgggagtg tcggttgttc ccctcttcct agctctcgat ctggctcatt
     9721 cagaccatcc cagactcaag atttatttac cccatacagg ggttgatgct gggatgattg
     9781 ataaacaggc agaaattgct caaacccatg ttaacgggaa atttaaagag gcattactag
     9841 agattactgg gcatacaaca ccagactggc gaaaagtccc tgttacttgc tataccctcg
     9901 ttccagggca agatcgcccc gtggcagcaa ccctttatgt tccgctcaat cccaatattg
     9961 aaaatgatgc agtcgcccaa gaacgggtct gtgccttctc ccaatctcaa ggagttgacc
    10021 cctcacccta cgagtcatta ctcaaggcaa tctccgataa gccactatct caattatcaa
    10081 cccacaattt cgtagcctat cgaccaggca aagatccgcg cttttcagtt tatcttgcac
    10141 caggagtcta taaacggtca taaactctag gaaaaaaaca tggggattga caaggatagt
    10201 tagcactgat aacacttgca ctggaaatac tttagtagga gcaagggtgt ataaggacac
    10261 aggttcaaac cgataaattg caatatagca atcctctaat cagttgtaat attttggtgg
    10321 tagttaggag tcagaattca taattttcaa gcttttcagc tcaaattaac tattataaaa
    10381 attgtcacga ccaatgcgcg gattgctata tacatctcca gaaaagagga agtagggagc
    10441 agggagcagg gagtagggag aaataattga tgatttctct gggataattg attttatttt
    10501 ttattattgg agatgtctaa tgggaaaact acaaggtaag gttgctatta ttacgggtgg
    10561 ttcgcgaggc attggacgag caatagcaga gcgacttgct caggatggag cgacaataat
    10621 gctaacctac ttacggaaca aagcgcttgc tgaagcggta gttgctcaga ttgaaacaca
    10681 ggggggacag gctagagcaa tggcggttga cctagctcaa cctgctgata ttgaacgact
    10741 cttcgagatg accgaggcga catggcaacg acttgatatt cttgttaaca gtgcggctga
    10801 actacagact ggcagcattg aatcgttttc aattcatgat tggcagcggg tatttgcagt
    10861 caattctaca gctccctttc tcacaatcca gcaagcggct cgtcgtttaa gtgcccatgg
    10921 ccgtattgtt aatgtctcta caatcaatac agtcttggca gaacctggca ttgcggccta
    10981 tgctgcaagt aaaggctctc tagaacaatt gactcgtgtc gctgcatggg aattggctga
    11041 tcgaggaatt acggtcaatt ctgtatcacc gggacccaca gatacagact tgcttcggac
    11101 aggtaatcca cctgaagttt tggagcaagc cattgcgatg actcctttag ggcgtcttgg
    11161 gcaacctaaa gatattgccg acgtagtggc ctttcttgtt gggaatgacg ggcgttggat
    11221 aacaggacaa aatttgagag ttacaggagg gttgatctaa
//
