BGC0000389: massetolide A biosynthetic gene cluster from Pseudomonas fluorescens SS101
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Location: 11,695 - 35,942 nt. (total: 24,248 nt).
This entry is originally from NCBI GenBank EU199081.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
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Gene details
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General
Compounds
Genes
NRP
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0000389
Short description massetolide A biosynthetic gene cluster from Pseudomonas fluorescens SS101
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP (Cyclic depsipeptide)
Loci NCBI GenBank: EU199081.2
Compounds
  • massetolide A
Species Pseudomonas fluorescens SS101 [taxonomy]
References
Chemical products information
massetolide A
Copy SMILES
C55H97N9O16
Chemical database entries
NPAtlas
ChEMBL
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABH06368.2
  • massB
11695 - 24618 (+) MassB
  • Scaffold biosynthesis
Activity assay
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Sequence-based prediction
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  • ABH06369.2
  • massC
24615 - 35942 (+) MassC
  • Scaffold biosynthesis
Activity assay
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Sequence-based prediction
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NRP-specific information
Subclass Cyclic depsipeptide
Cyclic? yes
Thioesterase genes
  • abh06369 (Unknown)
NRP-synthases
Gene Modules
ABH06367
Module A1
Specificity: Leucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Module A2
Specificity: Glutamate
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
ABH06368
Module B1
Specificity: Threonine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Module B2
Specificity: Isoleucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Module B3 [active]
Specificity: Leucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Module B4
Specificity: Serine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
ABH06369
Module B5
Specificity: Leucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Module B6 [active]
Specificity: Serine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Module B7
Specificity: Isoleucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: H2TUQKOCLKJUFX3XAH52M5HN, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
Similar known gene clusters
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Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
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