BGC0000392: mirubactin biosynthetic gene cluster from Actinosynnema mirum DSM 43827
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 3,113,324 - 3,141,040 nt. (total: 27,717 nt).
This entry is originally from NCBI GenBank CP001630.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000392
Short description mirubactin biosynthetic gene cluster from Actinosynnema mirum DSM 43827
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: CP001630.1
Compounds
  • mirubactin
Species Actinosynnema mirum DSM 43827 [taxonomy]
References
Chemical products information
mirubactin
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • Amir_2714
  • ACU36649.1
 3113324 - 3113875 (-) transcriptional regulator, TetR family
copy AA seq
copy Nt seq
  • Amir_2715
  • ACU36650.1
 3113968 - 3114873 (+) Luciferase-like monooxygenase
copy AA seq
copy Nt seq
  • Amir_2716
  • ACU36651.1
 3114940 - 3117765 (-) transcriptional regulator, LuxR family
copy AA seq
copy Nt seq
  • Amir_2717
  • ACU36652.1
 3118394 - 3119455 (-) phospho-2-dehydro-3-deoxyheptonate aldolase
copy AA seq
copy Nt seq
  • Amir_2718
  • ACU36653.1
 3119448 - 3120851 (-) drug resistance transporter, EmrB/QacA subfamily
copy AA seq
copy Nt seq
  • Amir_2719
  • ACU36654.1
 3120848 - 3131080 (-) amino acid adenylation domain protein
copy AA seq
copy Nt seq
  • Amir_2720
  • ACU36655.1
 3131153 - 3131938 (-) ABC transporter related
copy AA seq
copy Nt seq
  • Amir_2721
  • ACU36656.1
 3131935 - 3132951 (-) transport system permease protein
copy AA seq
copy Nt seq
  • Amir_2722
  • ACU36657.1
 3132948 - 3133946 (-) transport system permease protein
copy AA seq
copy Nt seq
  • Amir_2723
  • ACU36658.1
 3133943 - 3134965 (-) periplasmic binding protein
copy AA seq
copy Nt seq
  • Amir_2724
  • ACU36659.1
 3135012 - 3135947 (-) Siderophore-interacting protein
copy AA seq
copy Nt seq
  • Amir_2726
  • ACU36660.1
 3136848 - 3138524 (-) AMP-dependent synthetase and ligase
copy AA seq
copy Nt seq
  • Amir_2727
  • ACU36661.1
 3138521 - 3140032 (-) isochorismate synthase
copy AA seq
copy Nt seq
  • Amir_2728
  • ACU36662.1
 3140270 - 3141040 (-) short-chain dehydrogenase/reductase SDR
copy AA seq
copy Nt seq
NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
Amir_2719
Module ?
Specificity: arginine
Evidence for specificity:
  • Structure-based inference
  • Mass spectrometry
  • Sequence-based prediction
Module ?
Specificity: N5-formyl-N5-hydroxyornithine
Evidence for specificity:
  • Structure-based inference
  • Mass spectrometry
  • Sequence-based prediction
Amir_2726
Module ?
Specificity: 2,3-dihydroxybenzoic acid
Evidence for specificity:
  • Structure-based inference
  • Mass spectrometry
  • Sequence-based prediction
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.