BGC0000400

BGC0000400: paenibacterin biosynthetic gene cluster from Paenibacillus sp. OSY-SE

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Location: 1 - 52,556 nt. (total: 52,556 nt).
This entry is originally from NCBI GenBank JX899679.1.

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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General

Compounds

Genes

NRP

History

NRPS/PKS domains

KnownClusterBlast

General information about the BGC

MIBiG accession	BGC0000400
Short description	paenibacterin biosynthetic gene cluster from Paenibacillus sp. OSY-SE
Status	Minimal annotation: no A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s) Completeness: Unknown Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)	NRP
Loci	NCBI GenBank: JX899679.1
Compounds	paenibacterin
Species	Paenibacillus sp. OSY-SE [taxonomy]
References	Biosynthesis of the new broad-spectrum lipopeptide antibiotic paenibacterin in Paenibacillus thiaminolyticus OSY-SE. Huang E et al., Res Microbiol (2014) PMID:24607714

Chemical products information

paenibacterin

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C₇₉H₁₄₅N₁₇O₁₇

Chemical database entries
PubCHEM

List of genes involved in compound(s) production

Identifiers	Position	Product	Functions	Evidence	Extra
AGM16412.1 pbtA	1 - 19818 (+)	paenibacterin synthetase A			copy AA seq copy Nt seq
AGM16413.1 pbtB	19991 - 39241 (+)	paenibacterin synthetase B			copy AA seq copy Nt seq
AGM16414.1 pbtC	39356 - 48868 (+)	paenibacterin synthetase C			copy AA seq copy Nt seq
AGM16415.1 pbtD	49084 - 50796 (+)	paenibacterin ABC-transporter D			copy AA seq copy Nt seq
AGM16416.1 pbtE	50808 - 52556 (+)	paenibacterin ABC-transporter E			copy AA seq copy Nt seq

NRP-specific information

Subclass	N/A
Cyclic?	no

NRP-synthases

Gene	Modules
pbtA	Module ? Specificity: ornithine Evidence for specificity:
	Module ? Specificity: valine Evidence for specificity:
	Module ? Specificity: threonine Evidence for specificity:
	Module ? Specificity: ornithine Evidence for specificity:
	Module ? Specificity: serine Evidence for specificity:
pbtB	Module ? Specificity: valine Evidence for specificity:
	Module ? Specificity: lysine Evidence for specificity:
	Module ? Specificity: serine Evidence for specificity:
	Module ? Specificity: isoleucine Evidence for specificity:
	Module ? Specificity: proline Evidence for specificity:
pbtC	Module ? Specificity: valine Evidence for specificity:
	Module ? Specificity: lysine Evidence for specificity:
	Module ? Specificity: isoleucine Evidence for specificity:

Annotation changelog

MIBiG version	Submitter	Notes
1.0	Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).	Submitted
2.0	Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).	Migrated from v1.4 Updated compound(s) information (NPAtlas curation)
3.0	Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).	Updated bioactivity data Added NRP substrate specificities
3.1	Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).	Update chemical activity to schema version 2.11

Detailed domain annotation

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