BGC0000402: paenilarvin A biosynthetic gene cluster from Paenibacillus larvae subsp. larvae DSM 25430
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Location: 1,841,078 - 1,878,357 nt. (total: 37,280 nt).
This entry is originally from NCBI GenBank CP003355.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000402
Short description paenilarvin A biosynthetic gene cluster from Paenibacillus larvae subsp. larvae DSM 25430
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
CP003355.1
1841078 - 1878357
via
Compounds
  • paenilarvin A
  • paenilarvin B
  • paenilarvin C
Species Paenibacillus larvae subsp. larvae DSM 25430 [taxonomy]
References
Chemical products information
paenilarvin A Evidence:
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C52H81N13O14
Chemical database entries
PubCHEM
paenilarvin B Evidence:
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C52H80N12O15
Chemical database entries
PubCHEM
paenilarvin C Evidence:
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C50H77N13O14
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ERIC2_c18750
  • AHD05677.1
 1841078 - 1848883 (-) nonribosomal peptide ligase subunit
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    • ERIC2_c18760
    • AHD05678.1
    		 1849020 - 1865129 (-) nonribosomal peptide ligase subunit
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      • ERIC2_c18770
      • AHD05679.1
      		 1865173 - 1877127 (-) putative non-ribosomal peptide ligase/ polyketide synthase hybrid
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        • ERIC2_c18780
        • AHD05680.1
        		 1877158 - 1878357 (-) putative malonyl CoA-acyl carrier protein transacylase
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          Biosynthesis information

          Biosynthetic modules

          Name
          Unk01
          Type
          nrps-type1
          Genes
          ERIC2_c18750
          Substrates
          asparagine (evidence: Structure-based inference [1])
          Integrated Monomers
          Domains
          adenylation
          Name
          Unk02
          Type
          nrps-type1
          Genes
          ERIC2_c18750
          Substrates
          serine (evidence: Structure-based inference [1])
          Integrated Monomers
          Domains
          adenylation
          Name
          Unk03
          Type
          nrps-type1
          Genes
          ERIC2_c18760
          Substrates
          tyrosine (evidence: Structure-based inference [1])
          Integrated Monomers
          Domains
          adenylation
          Name
          Unk04
          Type
          nrps-type1
          Genes
          ERIC2_c18760
          Substrates
          asparagine (evidence: Structure-based inference [1])
          Integrated Monomers
          Domains
          adenylation
          Name
          Unk05
          Type
          nrps-type1
          Genes
          ERIC2_c18760
          Substrates
          glutamine (evidence: Structure-based inference [1])
          Integrated Monomers
          Domains
          adenylation
          Name
          Unk06
          Type
          nrps-type1
          Genes
          ERIC2_c18760
          Substrates
          proline (evidence: Structure-based inference [1])
          Integrated Monomers
          Domains
          adenylation
          Name
          Unk07
          Type
          nrps-type1
          Genes
          ERIC2_c18770
          Substrates
          asparagine (evidence: Structure-based inference [1])
          Integrated Monomers
          Domains
          adenylation
          Annotation changelog

          Entry version: 3

          Date
          Changes
          Submitters
          Reviewers
          2022-09-15
          Add compound details
          • (ID: SJG3CBEHSM6A3I74YXLH6GLA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          2022-09-15
          Added NRP substrate specificities
          • (ID: SJG3CBEHSM6A3I74YXLH6GLA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 2

          Date
          Changes
          Submitters
          Reviewers
          2019-10-16
          Migrated from v1.4
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 1

          Date
          Changes
          Submitters
          Reviewers
          2015-06-12
          Submitted
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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