BGC0000403: Pelgipeptin A biosynthetic gene cluster from Paenibacillus elgii
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Location: 1 - 40,806 nt. (total: 40,806 nt).
This entry is originally from NCBI GenBank JQ745271.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000403
Short description Pelgipeptin A biosynthetic gene cluster from Paenibacillus elgii
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
JQ745271.1
via
Compounds
  • Pelgipeptin A
  • Pelgipeptin B
  • Pelgipeptin C
  • Pelgipeptin D
Species Paenibacillus elgii [taxonomy]
References
Chemical products information
Pelgipeptin A Evidence: MS/MS [2]
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C52H88N12O12
Chemical database entries
NPAtlas
Pelgipeptin B Evidence: MS/MS [2]
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C54H92N12O12
Chemical database entries
NPAtlas
Pelgipeptin C Evidence: MS/MS [1]
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C53H90N12O12
Pelgipeptin D Evidence: MS/MS [1]
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C53H90N12O12
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AFJ14790.1
  • plpA
 1 - 1287 (+) PlpA
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    • AFJ14791.1
    • plpB
    		 1362 - 2924 (+) PlpB
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      • AFJ14792.1
      • plpC
      		 2934 - 3668 (+) PlpC
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        • AFJ14793.1
        • plpD
        		 3838 - 8364 (+) PlpD
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          • AFJ14794.1
          • plpE
          		 8405 - 33826 (+) PlpE
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            • AFJ14795.1
            • plpF
            		 33932 - 37249 (+) PlpF
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              • AFJ14796.1
              • plpG
              		 37292 - 39076 (+) PlpG
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                • AFJ14797.1
                • plpH
                		 39073 - 40806 (+) PlpH
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                  Biosynthesis information

                  Biosynthetic modules

                  Name
                  Unk01
                  Type
                  nrps-type1
                  Genes
                  plpD
                  Substrates
                  2,4-diaminobutyric acid (evidence: Sequence-based prediction, Structure-based inference, Enzyme-coupled assay)
                  Integrated Monomers
                  Domains
                  adenylation
                  Name
                  Unk02
                  Type
                  nrps-type1
                  Genes
                  plpE
                  Substrates
                  isoleucine (evidence: Sequence-based prediction, Structure-based inference, Enzyme-coupled assay)
                  Integrated Monomers
                  Domains
                  adenylation
                  Name
                  Unk03
                  Type
                  nrps-type1
                  Genes
                  plpE
                  Substrates
                  2,4-diaminobutyric acid (evidence: Sequence-based prediction, Structure-based inference)
                  Integrated Monomers
                  Domains
                  adenylation
                  Name
                  Unk04
                  Type
                  nrps-type1
                  Genes
                  plpE
                  Substrates
                  phenylalanine (evidence: Sequence-based prediction, Structure-based inference, Enzyme-coupled assay)
                  Integrated Monomers
                  Domains
                  adenylation
                  Name
                  Unk05
                  Type
                  nrps-type1
                  Genes
                  plpE
                  Substrates
                  leucine (evidence: Sequence-based prediction, Structure-based inference)
                  Integrated Monomers
                  Domains
                  adenylation
                  Name
                  Unk06
                  Type
                  nrps-type1
                  Genes
                  plpE
                  Substrates
                  2,4-diaminobutyric acid (evidence: Sequence-based prediction, Structure-based inference)
                  Integrated Monomers
                  Domains
                  adenylation
                  Name
                  Unk07
                  Type
                  nrps-type1
                  Genes
                  plpE
                  Substrates
                  valine (evidence: Sequence-based prediction, Structure-based inference)
                  Integrated Monomers
                  Domains
                  adenylation
                  Name
                  Unk08
                  Type
                  nrps-type1
                  Genes
                  plpE
                  Substrates
                  leucine (evidence: Sequence-based prediction, Structure-based inference)
                  Integrated Monomers
                  Domains
                  adenylation
                  Name
                  Unk09
                  Type
                  nrps-type1
                  Genes
                  plpF
                  Substrates
                  serine (evidence: Sequence-based prediction, Structure-based inference, Enzyme-coupled assay)
                  Integrated Monomers
                  Domains
                  adenylation
                  Annotation changelog

                  Entry version: next

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2024-03-20
                  MIBiG v4 annotathon
                  • (ID: 5SRAIADCX5E626OGO7LYHFZD)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 4

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2022-10-07
                  Update chemical activity to schema version 2.11
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 3

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2022-09-15
                  Updated bioactivity data
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  2022-09-15
                  Added NRP substrate specificities
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 2

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2019-10-16
                  Migrated from v1.4
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 1

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2015-06-12
                  Submitted
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  Detailed domain annotation
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