BGC0000404: penicillin biosynthetic gene cluster from Penicillium chrysogenum
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Location: 1 - 56,820 nt. (total: 56,820 nt).
This entry is originally from NCBI GenBank DQ192518.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000404
Short description penicillin biosynthetic gene cluster from Penicillium chrysogenum
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: DQ192518.1
Compounds
  • penicillin
Species Penicillium chrysogenum [taxonomy]
References
Chemical products information
penicillin
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C16H17N2Na1O4S1
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABA70575.1
 1969 - 2847 (-) hypothetical protein
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  • ABA70576.1
 3499 - 4725 (-) hypothetical protein
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  • ABA70577.1
 5170 - 6387 (+) hypothetical protein
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  • ABA70578.1
 7551 - 9902 (+) hypothetical protein
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  • ABA70579.1
 12451 - 13338 (+) hypothetical protein
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  • ABA70580.1
 13796 - 15676 (-) hypothetical protein
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  • ABA70581.1
 16301 - 18194 (-) hypothetical protein
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  • ABA70582.1
  • pcbAB
 23318 - 34654 (-) alpha-aminoadypil-cysteinyl-valine synthetase
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  • ABA70583.1
  • pcbC
 35670 - 36665 (+) isopenicillin N synthetase
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  • ABA70584.1
  • penDE
 38163 - 39437 (+) acyl-coenzyme A:Isopenicillin N acyltransferase
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  • ABA70585.1
 40456 - 42020 (-) hypothetical protein
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  • ABA70586.1
 42560 - 43915 (+) hypothetical protein
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  • ABA70587.1
 46934 - 47398 (+) hypothetical protein
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  • ABA70588.1
 52260 - 52819 (-) hypothetical protein
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  • ABA70589.1
 54319 - 55297 (+) hypothetical protein
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  • ABA70590.1
 55514 - 56662 (+) hypothetical protein
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
pcbAB
Module ?
Specificity: 2-aminoadipic acid
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: cysteine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
Detailed domain annotation
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