BGC0000406: phosphinothricintripeptide biosynthetic gene cluster from Streptomyces viridochromogenes
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Location: 1 - 37,823 nt. (total: 37,823 nt).
This entry is originally from NCBI GenBank X65195.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000406
Short description phosphinothricintripeptide biosynthetic gene cluster from Streptomyces viridochromogenes
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: X65195.2
Compounds
  • phosphinothricintripeptide
Species Streptomyces viridochromogenes [taxonomy]
References
Chemical products information
phosphinothricintripeptide [synonyms: phosphinothricin, bialaphos, glufosinate, basta]
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C5H11N1O4P1
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAJ14034.1
117 - 530 (+) hypothetical protein
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  • CAJ14035.1
670 - 1557 (+) hypothetical protein
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  • CAJ14036.1
2172 - 2381 (+) hypothetical protein
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  • CAJ14037.1
  • phsB
2378 - 5947 (+) peptide synthetase
  • Activation / processing
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  • CAJ14038.1
5940 - 7601 (+) hypothetical protein
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  • CAJ14039.1
  • phsC
7674 - 10934 (+) peptide synthetase
  • Activation / processing
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  • CAJ14040.1
  • pmi
11045 - 13714 (+) phosphinomethylmalate isomerase
  • Precursor biosynthesis
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  • CAJ14041.1
  • adhP
13771 - 14958 (+) putative alcohol dehydrogenase
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  • CAJ14042.1
14982 - 16280 (+) hypothetical protein
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  • CAJ14043.1
  • pgdP
16291 - 17301 (+) putative D-3-phosphoglycerate dehydrogenase
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  • CAJ14044.1
  • ppm
17346 - 18287 (+) PEP-phosphomutase
  • Precursor biosynthesis
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  • CAJ14045.1
  • ppd
18284 - 19477 (+) phosphonopyruvate decarboxylase
  • Precursor biosynthesis
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  • CAJ14046.1
19474 - 20028 (+) hypothetical protein
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  • CAJ14047.1
  • pgmP
20084 - 21343 (+) putative phosphoglycerate mutase
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  • CAJ14048.1
  • cpps
21340 - 22536 (+) carboxyphosphoenolpyruvate synthase
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  • CAJ14049.1
  • cppm
22611 - 23501 (+) carboxyphosphoenolpyruvate mutase
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  • CAJ14050.1
  • aldP
23552 - 24952 (+) putative aldehyde dehydrogenase
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  • CAJ14051.1
  • pmet
25008 - 26657 (+) P-methyltransferase
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  • CAA46312.2
  • pms
26654 - 27976 (+) 2-phosphinomethylmalic acid synthase
  • Precursor biosynthesis
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  • CAA46313.1
  • phsA
28010 - 29878 (+) peptide synthetase
  • Activation / processing
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  • CAA46314.1
  • pat
29930 - 30481 (+) phosphinothricin acetyl transferase
  • Resistance/immunity
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  • CAA46315.1
  • dea
30493 - 31392 (+) phosphinothricin tripeptide acetyl hydrolase
  • Tailoring (Acetylation)
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  • CAJ14052.1
  • the1
31389 - 32147 (+) thioesterase
  • Unknown
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  • CAJ14053.1
  • the2
32144 - 32926 (+) thioesterase
  • Unknown
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  • CAJ14054.1
  • trs
32923 - 34161 (+) putative membrane transport protein
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  • CAJ14055.1
  • prpA
34483 - 35388 (+) regulatory protein
  • Regulation
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  • CAJ14056.1
35362 - 36612 (-) hypothetical protein
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  • CAJ14057.1
36630 - 37208 (+) hypothetical protein
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  • CAJ14058.1
37254 - >37823 (+) hypothetical protein
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NRP-specific information
Subclass N/A
Cyclic? no
Release type
  • Hydrolysis
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: VIL6M54V5UQOLZ6MKZLRAOWY, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected gene identifiers
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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