BGC0000412: pyochelin biosynthetic gene cluster from Pseudomonas aeruginosa PAO1
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Location: 1 - 15,023 nt. (total: 15,023 nt).
This entry is originally from NCBI GenBank AF074705.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000412
Short description pyochelin biosynthetic gene cluster from Pseudomonas aeruginosa PAO1
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
AF074705.2
via
Compounds
  • pyochelin
Species Pseudomonas aeruginosa PAO1 [taxonomy]
References
Chemical products information
pyochelin Evidence:
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C14H16N2O3S2
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAC83656.1
  • pchE
 805 - 5121 (+) dihydroaeruginoic acid synthetase
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    • AAC83657.1
    • pchF
    		 5118 - 10547 (+) pyochelin synthetase
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      • AAK01463.1
      • pchG
      		 10544 - 11593 (+) reductase
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        • AAK01464.1
        • pchH
        		 11590 - 13302 (+) ABC transporter
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          • AAK01462.1
          • pchI
          		 13299 - 15023 (+) ABC transporter
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            Biosynthesis information

            Biosynthetic modules

            Name
            Unk01
            Type
            nrps-type1
            Genes
            pchE
            Substrates
            cysteine (evidence: )
            Integrated Monomers
            Domains
            adenylation
            Name
            Unk02
            Type
            nrps-type1
            Genes
            pchF
            Substrates
            cysteine (evidence: )
            Integrated Monomers
            Domains
            adenylation
            Annotation changelog

            Entry version: 4

            Date
            Changes
            Submitters
            Reviewers
            2022-10-07
            Update chemical activity to schema version 2.11
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 3

            Date
            Changes
            Submitters
            Reviewers
            2022-09-15
            Updated bioactivity data
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            2022-09-15
            Added NRP substrate specificities
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 2

            Date
            Changes
            Submitters
            Reviewers
            2019-10-16
            Migrated from v1.4
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            2019-10-16
            Updated compound(s) information (NPAtlas curation)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 1

            Date
            Changes
            Submitters
            Reviewers
            2015-06-12
            Submitted
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            Detailed domain annotation
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