BGC0000415: quinomycin biosynthetic gene cluster from Streptomyces griseovariabilis subsp. bandungensis
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Location: 1 - 36,568 nt. (total: 36,568 nt).
This entry is originally from NCBI GenBank JN852959.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000415
Short description quinomycin biosynthetic gene cluster from Streptomyces griseovariabilis subsp. bandungensis
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: JN852959.1
Compounds
  • quinomycin
Species Streptomyces griseovariabilis subsp. bandungensis [taxonomy]
References
Chemical products information
quinomycin
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C51H64N12O12S2
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AET98900.1
  • qui1
 3 - 155 (+) putative ABC transporter
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  • AET98901.1
  • qui2
 152 - 976 (+) putative ABC transporter
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  • AET98902.1
  • qui3
 1083 - 2288 (+) putative esterase
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  • AET98903.1
  • qui4
 2408 - 2938 (-) putative DNA-binding response regulator
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  • AET98904.1
  • qui5
 3055 - 3267 (-) MbtH-like protein
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  • AET98905.1
  • qui6
 3314 - 12751 (-) putative non-ribosomal peptide synthetase
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  • AET98906.1
  • qui7
 12759 - 20753 (-) putative non-ribosomal peptide synthetase
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  • AET98907.1
  • qui8
 20818 - 21516 (+) putative SAM-dependent methyltransferase
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  • AET98908.1
  • qui10
 23150 - 25528 (+) UvrA-like protein
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  • AET98909.1
  • qui11
 25610 - 26548 (+) putative oxidoreductase
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  • AET98910.1
  • qui12
 26945 - 28333 (-) putative FAD-dependent oxidoreductase
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  • AET98911.1
  • qui13
 28392 - 29480 (-) putative dehydrogenase
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  • AET98912.1
  • qui14
 29477 - 30223 (-) putative thioesterase
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  • AET98913.1
  • qui15
 30377 - 31582 (+) putative cytochrome P450
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  • AET98914.1
  • qui16
 31596 - 33179 (+) putative AMP-binding ligase
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  • AET98915.1
  • qui17
 33254 - 34078 (-) putative tryptophan 2,3-dioxygenase
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  • AET98916.1
  • qui18
 34133 - 35965 (+) putative non-ribosomal peptide synthetase
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
qui6
Module ?
Specificity: cysteine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
qui7
Module ?
Specificity: serine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: alanine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
qui16
Module ?
Specificity: quinoxaline-2-carboxylic acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
qui18
Module ?
Specificity: tryptophan
Evidence for specificity:
  • Mass spectrometry
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated reference publication(s) (MIBiG Annotathon)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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