LOCUS       BGC0000417             12076 bp    DNA     linear   BCT 31-JAN-2014
DEFINITION  Rhodococcus jostii RHA1, complete genome.
ACCESSION   BGC0000417
VERSION     BGC0000417
KEYWORDS    .
SOURCE      Rhodococcus jostii RHA1
  ORGANISM  Rhodococcus jostii RHA1
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Rhodococcus.
COMMENT     Bacteria available by contacting Lindsay Eltis (leltis [at]
            interchange.ubc.ca).
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 13:35:09
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 2443455
            Orig. end    :: 2455531
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..648
                     /EC_number="3.3.2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:isochorismatase (Score: 299.2; E-value: 3.5e-91)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RHA1_ro02318"
                     /note="GO_function: GO:0003700 - transcription factor
                     activity; GO_function: GO:0008908 - isochorismatase
                     activity; GO_function: GO:0048037 - cofactor binding;
                     GO_process: GO:0006355 - regulation of transcription,
                     DNA-dependent; GO_process: GO:0006826 - iron ion transport;
                     GO_process: GO:0009239 - enterobactin biosynthesis"
                     /product="isochorismatase"
                     /protein_id="ABG94124.1"
                     /transl_table=11
                     /translation="MAIPPISTYTIPEIHEVPESKVSWRLDPRRSALLVHDMQNYFIDA
                     YDVRAEPMSTAMANMVRIRELCSEAGIPVIYTMQPGDQHPSRRGILADFWGPGLTSGRD
                     TEVVEPLAPREGDIQVTKWRYSAFQRTDLRQLLGHHGRDQLIVTGVYAHMGCMLSAAEA
                     FMSDVQPFLVSDATADFSRDEHLMALTYAAKRCGSVTTTDALVSALSPLEVG"
     subregion       1..12076
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="NRPS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..12076
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..648
                     /locus_tag="RHA1_ro02318"
     gene            820..7920
                     /locus_tag="RHA1_ro02319"
     CDS             820..7920
                     /EC_number="5.1.1.13"
                     /NRPS_PKS="Domain: Condensation_Starter (19-301). E-value:
                     1.1e-53. Score: 174.4. Matches aSDomain:
                     nrpspksdomains_RHA1_ro02319_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (454-843). E-value:
                     2.6e-102. Score: 334.3. Matches aSDomain:
                     nrpspksdomains_RHA1_ro02319_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (951-1019). E-value: 6.4e-22. Score:
                     69.5. Matches aSDomain: nrpspksdomains_RHA1_ro02319_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1038-1334). E-value:
                     3e-86. Score: 280.9. Matches aSDomain:
                     nrpspksdomains_RHA1_ro02319_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1499-1906). E-value:
                     9.9e-98. Score: 319.2. Matches aSDomain:
                     nrpspksdomains_RHA1_ro02319_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2013-2082). E-value: 4.5e-25.
                     Score: 79.6. Matches aSDomain:
                     nrpspksdomains_RHA1_ro02319_PCP.2"
                     /NRPS_PKS="Domain: Thioesterase (2101-2334). E-value:
                     2.7e-39. Score: 127.8. Matches aSDomain:
                     nrpspksdomains_RHA1_ro02319_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 379;
                     E-value: 5e-115)"
                     /gene_kind="biosynthetic"
                     /locus_tag="RHA1_ro02319"
                     /note="GO_function: GO:0005554 - molecular function
                     unknown; GO_function: GO:0008757 -
                     S-adenosylmethionine-dependent methyltransferase activity;
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds; GO_function: GO:0016853 - isomerase activity;
                     GO_function: GO:0016874 - ligase activity; GO_function:
                     GO:0031177 - phosphopantetheine binding; GO_function:
                     GO:0048037 - cofactor binding; GO_process: GO:0017000 -
                     antibiotic biosynthesis"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="ABG94125.1"
                     /sec_met_domain="AMP-binding (E-value: 3e-115, bitscore:
                     373.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 9e-54, bitscore:
                     171.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2e-17, bitscore:
                     52.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLSISLPSTLQTGEDTADVCLTAAQRELWSGHQLDPTRSAFTTA
                     EYVEVAAPVDIDALAAAVRTVIEEAEILSVRFEAEPGADSADVVQVHDRRHAPELERLQ
                     LDRAAALEWMREDVRRPLDFDSAPLVRTALITTESGVLWYLRAPHALLDAYGYSLLTRR
                     VAALYAARLAGTEPRPAKFPPLRTHVQAAREFDAAAPDSAPQSASHPVGFSDTVRRPVP
                     DPRRYTIPIDPDVARSLREAATAQATTWAEAVYAAAATYLGAHTGAEEVTLRVPVLARN
                     GIELASPVTATNIVPLRIPLDARSTFADVIGRVAAAWSETRPFQRVREAGRRATGGAVV
                     NVKPFAGRIAFGPTFGAVHQLATGPVEDVVISVSGAGDELTLEWAGNPDVYTDDEIRHH
                     AHRFAHYLRTISVAAEPVSVVDVCAPDELHLWRSAAGLDRTTGTAATLPDNIVSAFLAQ
                     ARTHPDRVAVNDLSYRELSTRSAALARQLRSAGAGRGTVVAVSLPRGTDLIVAVLAILR
                     SGATYLPIDPSSPAERARFILRDAQPSLGIGSADLLGDLPRVEEDSAQSASGELDNAVQ
                     ADDIAYVIYTSGSTGVPKGVPIPHRNVMRLFDVSREWFTFTEDDCWPLLHSYAFDFSVW
                     EIWGALLHGGRLVTVDEATLTSPADLAGLLVDEGVTVLNQTPSAFGHLVDALVRADSFD
                     RLRLRYVVFGGEALDPAVLRAWFAATGPDEGAELVNMYGITETTVHVTATKVTAADVVD
                     IGVPLGDLRTYVLGPGLRPVPPGVTGEIYVSGPGLSPGYLGRPDLTSGRFVADPFAPGG
                     TRMYRTGDLARYDATGTLHYHGRIDDQIQLRGYRVELGEIGAAMTAVPDVQAAVATAHE
                     QAGGDQRIVGYVVPRPGGEHDAVEEQVRAHLVRSLPGYMTPSALVMLDRLPLTHNGKVD
                     KDALPAPRWLGQAGDTPRTDTEARILPLFTSVLGAEQVGVHDDFFALGGNSLLAAALVS
                     AITAELAVPLRVATVFENPTVAAVAAQLEDAGERVSASRPSPRDLPEGTPVPLSPAQER
                     LWFLDSAAGGGTYLLALAVDFGEGLEPDALSAALGDVVTRHQSLRTVFPLVDSVPHQVV
                     LPAGDAKVRLERVDNVGNIEGHIAAMTTVGLGLTDQPPLRAVLYEPQHTLVLLLHHIIG
                     DEWSQSRLLDDLAFAYNARRAGRAPEFTPLPLQYPDVAVWQRERIGAGDDATPLLTGQL
                     DYWREQLAGLPLELGWRTDRPRPALPTNRGASVHRTLSPSLHAAVESLAAERRASFFMI
                     VHAAVAVLLERLGAGEDIALGVPVAGRSHPDLDAMVGCFINTVVLRTDVSGDPTFDDLL
                     DRVRAVDLDAVDYADVPFNRIVELVNPPRSSARHPLFQVMLSHWKQDGAAARFDGTTAA
                     VRMLDATSAKFDLALRFQERPDSGGVDVTFEYSTELFDAATVESFADRLAVVIERLVAN
                     HEQRIARVDILTPQERGRVLGEWSHAEHSVPARTFDEYFSAQVAETPDAEALAVGASVR
                     PAVSLTYRQLDERANRIAHLLISRGAGPGDVVALALDRSAELIISVLAVLKSGAAYLPV
                     DPTYPADRIAHMLADGAPVAILTSSVGVPDRTPLGTDVPILDLDDPGLQSLLDTQPVTA
                     PTDADRSRPLKLDDAAYLIYTSGSTGVPKGVVVPHRGIADLLSLQSDVIGMDHTTRALH
                     FSSISFDLAFWQIMWGVLSGGTLVVATDADRIPGEPLARVINEHDVNFVGVPPSFAAAF
                     PPEHPIPDGVDLMLGAEKLTPQLIERYAPGRRLFNAYGPTECTVNATLALVEPGHEGPV
                     PIGVVDPGKHAYVLDHALRPVPPGVSGELYLAGDSVTRGYRNQSPKTAERFIADPFAVP
                     GSRMYRTSDVVWWGRDGQIYFTGRADSQVKVRGFRIELNEIEAVLSGDPDVEHIVVVVR
                     EDRPGDQRLVAYATSVPGGRIDPDQLHRRAASRLPDYMIPAAFIAVDEFPTLPNGKLDQ
                     TSLPVPHLSLQVSERGPRTAREEVLCQLFAEALGIERVGIDDSFFDLGGHSLMAAGLMS
                     AISKRLSVTATVASLFAAPTVAQLAGRLDDDHDADALAVLLPFRTEGSKPPVFCFHPAG
                     GISWGYSGLLRHIDDDYPLYGVQASNLSTSERPPETLEDMAAEYIEHMRTVQPEGPYHL
                     LGWSLGGVVAHAIAGALQNQGEELGMLVMLDSFPSDAWASMPTEQDALAALLYMVGYDP
                     EPLLASDTEPHRGGGLDRQQVIDILRGEGSALAGINEHTPAAMIDNFANAVRLESEPSQ
                     IVVDSDMLFFTAARNPATAATYDLWRPYLTGTIVNHDLDCEHKDMTQPRWIGEVGSVVN
                     EALASFGSRMNPINTEQGDR"
     aSDomain        877..1722
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RHA1_ro02319_Condensation_Starte
                     r.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="1.10E-53"
                     /label="RHA1_ro02319_Condensation_Starter.1"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="301"
                     /protein_start="19"
                     /score="174.4"
                     /tool="antismash"
                     /translation="VCLTAAQRELWSGHQLDPTRSAFTTAEYVEVAAPVDIDALAAAVR
                     TVIEEAEILSVRFEAEPGADSADVVQVHDRRHAPELERLQLDRAAALEWMREDVRRPLD
                     FDSAPLVRTALITTESGVLWYLRAPHALLDAYGYSLLTRRVAALYAARLAGTEPRPAKF
                     PPLRTHVQAAREFDAAAPDSAPQSASHPVGFSDTVRRPVPDPRRYTIPIDPDVARSLRE
                     AATAQATTWAEAVYAAAATYLGAHTGAEEVTLRVPVLARNGIELASPVTATNIVPLRIP
                     L"
     aSModule        877..3876
                     /complete
                     /domains="nrpspksdomains_RHA1_ro02319_Condensation_Starter.
                     1"
                     /domains="nrpspksdomains_RHA1_ro02319_AMP-binding.1"
                     /domains="nrpspksdomains_RHA1_ro02319_PCP.1"
                     /locus_tags="RHA1_ro02319"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       883..915
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0001"
                     /evalue="2.70E-01"
                     /label="C1_starter_004-017"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="32"
                     /protein_start="21"
                     /score="4.8"
                     /tool="antismash"
                     /translation="LTAAQRELWSG"
     CDS_motif       940..1053
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0002"
                     /evalue="2.70E-12"
                     /label="C2_starter_024-063"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="78"
                     /protein_start="40"
                     /score="39.3"
                     /tool="antismash"
                     /translation="AFTTAEYVEVAAPVDIDALAAAVRTVIEEAEILSVRFE"
     CDS_motif       1264..1323
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0003"
                     /evalue="4.40E-07"
                     /label="C3_starter_134-155"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="168"
                     /protein_start="148"
                     /score="22.8"
                     /tool="antismash"
                     /translation="HALLDAYGYSLLTRRVAALY"
     CDS_motif       1627..1713
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0004"
                     /evalue="1.90E-01"
                     /label="C5_starter_265-294"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="298"
                     /protein_start="269"
                     /score="4.4"
                     /tool="antismash"
                     /translation="EVTLRVPVLARNGIELASPVTATNIVPLR"
     aSDomain        2182..3348
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RHA1_ro02319_AMP-binding.1"
                     /evalue="2.60E-102"
                     /label="RHA1_ro02319_AMP-binding.1"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="843"
                     /protein_start="454"
                     /score="334.3"
                     /tool="antismash"
                     /translation="FLAQARTHPDRVAVNDLSYRELSTRSAALARQLRSAGAGRGTVVA
                     VSLPRGTDLIVAVLAILRSGATYLPIDPSSPAERARFILRDAQPSLGIGSADLLGDLPR
                     VEEDSAQSASGELDNAVQADDIAYVIYTSGSTGVPKGVPIPHRNVMRLFDVSREWFTFT
                     EDDCWPLLHSYAFDFSVWEIWGALLHGGRLVTVDEATLTSPADLAGLLVDEGVTVLNQT
                     PSAFGHLVDALVRADSFDRLRLRYVVFGGEALDPAVLRAWFAATGPDEGAELVNMYGIT
                     ETTVHVTATKVTAADVVDIGVPLGDLRTYVLGPGLRPVPPGVTGEIYVSGPGLSPGYLG
                     RPDLTSGRFVADPFAPGGTRMYRTGDLARYDATGTLHYHGRIDDQIQLR"
     CDS_motif       2356..2397
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0005"
                     /evalue="1.10E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="526"
                     /protein_start="512"
                     /score="12.5"
                     /tool="antismash"
                     /translation="LAILRSGATYLPID"
     CDS_motif       2560..2619
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0006"
                     /evalue="2.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="600"
                     /protein_start="580"
                     /score="29.3"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGVPKGVPIPH"
     CDS_motif       3013..3036
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0007"
                     /evalue="2.20E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="739"
                     /protein_start="731"
                     /score="2.1"
                     /tool="antismash"
                     /translation="YGITETTV"
     CDS_motif       3139..3228
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0008"
                     /evalue="3.80E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="803"
                     /protein_start="773"
                     /score="44.8"
                     /tool="antismash"
                     /translation="PPGVTGEIYVSGPGLSPGYLGRPDLTSGRF"
     CDS_motif       3313..3375
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0009"
                     /evalue="1.90E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="852"
                     /protein_start="831"
                     /score="29.7"
                     /tool="antismash"
                     /translation="YHGRIDDQIQLRGYRVELGEI"
     aSDomain        3673..3876
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RHA1_ro02319_PCP.1"
                     /evalue="6.40E-22"
                     /label="RHA1_ro02319_PCP.1"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="1019"
                     /protein_start="951"
                     /score="69.5"
                     /tool="antismash"
                     /translation="EARILPLFTSVLGAEQVGVHDDFFALGGNSLLAAALVSAITAELA
                     VPLRVATVFENPTVAAVAAQLED"
     aSDomain        3934..4821
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RHA1_ro02319_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.00E-86"
                     /label="RHA1_ro02319_Condensation_LCL.1"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="1334"
                     /protein_start="1038"
                     /score="280.9"
                     /tool="antismash"
                     /translation="PVPLSPAQERLWFLDSAAGGGTYLLALAVDFGEGLEPDALSAALG
                     DVVTRHQSLRTVFPLVDSVPHQVVLPAGDAKVRLERVDNVGNIEGHIAAMTTVGLGLTD
                     QPPLRAVLYEPQHTLVLLLHHIIGDEWSQSRLLDDLAFAYNARRAGRAPEFTPLPLQYP
                     DVAVWQRERIGAGDDATPLLTGQLDYWREQLAGLPLELGWRTDRPRPALPTNRGASVHR
                     TLSPSLHAAVESLAAERRASFFMIVHAAVAVLLERLGAGEDIALGVPVAGRSHPDLDAM
                     VGCFINTVVLRTDVS"
     aSModule        3934..7821
                     /complete
                     /domains="nrpspksdomains_RHA1_ro02319_Condensation_LCL.1"
                     /domains="nrpspksdomains_RHA1_ro02319_AMP-binding.2"
                     /domains="nrpspksdomains_RHA1_ro02319_PCP.2"
                     /domains="nrpspksdomains_RHA1_ro02319_Thioesterase.1"
                     /final_module
                     /locus_tags="RHA1_ro02319"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3940..3972
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0010"
                     /evalue="1.40E-01"
                     /label="C1_starter_004-017"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="1051"
                     /protein_start="1040"
                     /score="5.7"
                     /tool="antismash"
                     /translation="PLSPAQERLWF"
     CDS_motif       3997..4110
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0011"
                     /evalue="7.60E-09"
                     /label="C2_DCL_024-062"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="1097"
                     /protein_start="1059"
                     /score="27.9"
                     /tool="antismash"
                     /translation="TYLLALAVDFGEGLEPDALSAALGDVVTRHQSLRTVFP"
     CDS_motif       4300..4365
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0012"
                     /evalue="3.70E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="1182"
                     /protein_start="1160"
                     /score="19.6"
                     /tool="antismash"
                     /translation="LHHIIGDEWSQSRLLDDLAFAY"
     CDS_motif       4414..4449
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0013"
                     /evalue="2.70E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="1210"
                     /protein_start="1198"
                     /score="10.5"
                     /tool="antismash"
                     /translation="QYPDVAVWQRER"
     CDS_motif       4720..4809
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0014"
                     /evalue="1.00E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="1330"
                     /protein_start="1300"
                     /score="46.8"
                     /tool="antismash"
                     /translation="DIALGVPVAGRSHPDLDAMVGCFINTVVLR"
     CDS_motif       4858..4977
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0015"
                     /evalue="1.50E-16"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="1386"
                     /protein_start="1346"
                     /score="52.7"
                     /tool="antismash"
                     /translation="RAVDLDAVDYADVPFNRIVELVNPPRSSARHPLFQVMLSH"
     aSDomain        5317..6537
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RHA1_ro02319_AMP-binding.2"
                     /evalue="9.90E-98"
                     /label="RHA1_ro02319_AMP-binding.2"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="1906"
                     /protein_start="1499"
                     /score="319.2"
                     /tool="antismash"
                     /translation="FSAQVAETPDAEALAVGASVRPAVSLTYRQLDERANRIAHLLISR
                     GAGPGDVVALALDRSAELIISVLAVLKSGAAYLPVDPTYPADRIAHMLADGAPVAILTS
                     SVGVPDRTPLGTDVPILDLDDPGLQSLLDTQPVTAPTDADRSRPLKLDDAAYLIYTSGS
                     TGVPKGVVVPHRGIADLLSLQSDVIGMDHTTRALHFSSISFDLAFWQIMWGVLSGGTLV
                     VATDADRIPGEPLARVINEHDVNFVGVPPSFAAAFPPEHPIPDGVDLMLGAEKLTPQLI
                     ERYAPGRRLFNAYGPTECTVNATLALVEPGHEGPVPIGVVDPGKHAYVLDHALRPVPPG
                     VSGELYLAGDSVTRGYRNQSPKTAERFIADPFAVPGSRMYRTSDVVWWGRDGQIYFTGR
                     ADSQVKVR"
     CDS_motif       5518..5559
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0016"
                     /evalue="9.60E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="1580"
                     /protein_start="1566"
                     /score="15.7"
                     /tool="antismash"
                     /translation="LAVLKSGAAYLPVD"
     CDS_motif       5779..5838
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0017"
                     /evalue="7.60E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="1673"
                     /protein_start="1653"
                     /score="30.7"
                     /tool="antismash"
                     /translation="AYLIYTSGSTGVPKGVVVPH"
     CDS_motif       5929..5952
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0018"
                     /evalue="4.50E+01"
                     /label="C4_LCL_164-176"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="1711"
                     /protein_start="1703"
                     /score="-2.4"
                     /tool="antismash"
                     /translation="DLAFWQIM"
     CDS_motif       6196..6222
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0019"
                     /evalue="2.00E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="1801"
                     /protein_start="1792"
                     /score="7.9"
                     /tool="antismash"
                     /translation="YGPTECTVN"
     CDS_motif       6328..6417
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0020"
                     /evalue="7.60E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="1866"
                     /protein_start="1836"
                     /score="40.6"
                     /tool="antismash"
                     /translation="PPGVSGELYLAGDSVTRGYRNQSPKTAERF"
     CDS_motif       6502..6567
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0021"
                     /evalue="8.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="1916"
                     /protein_start="1894"
                     /score="33.9"
                     /tool="antismash"
                     /translation="FTGRADSQVKVRGFRIELNEIE"
     aSDomain        6859..7065
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RHA1_ro02319_PCP.2"
                     /evalue="4.50E-25"
                     /label="RHA1_ro02319_PCP.2"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="2082"
                     /protein_start="2013"
                     /score="79.6"
                     /tool="antismash"
                     /translation="EEVLCQLFAEALGIERVGIDDSFFDLGGHSLMAAGLMSAISKRLS
                     VTATVASLFAAPTVAQLAGRLDDD"
     CDS_motif       7123..7152
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0022"
                     /evalue="8.10E-03"
                     /label="NRPS-beforete1"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="2111"
                     /protein_start="2101"
                     /score="9.3"
                     /tool="antismash"
                     /translation="PVFCFHPAGG"
     aSDomain        7123..7821
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RHA1_ro02319_Thioesterase.1"
                     /evalue="2.70E-39"
                     /label="RHA1_ro02319_Thioesterase.1"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="2334"
                     /protein_start="2101"
                     /score="127.8"
                     /tool="antismash"
                     /translation="PVFCFHPAGGISWGYSGLLRHIDDDYPLYGVQASNLSTSERPPET
                     LEDMAAEYIEHMRTVQPEGPYHLLGWSLGGVVAHAIAGALQNQGEELGMLVMLDSFPSD
                     AWASMPTEQDALAALLYMVGYDPEPLLASDTEPHRGGGLDRQQVIDILRGEGSALAGIN
                     EHTPAAMIDNFANAVRLESEPSQIVVDSDMLFFTAARNPATAATYDLWRPYLTGTIVNH
                     DLDCEHKDMTQ"
     CDS_motif       7303..7377
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RHA1_ro02319_0023"
                     /evalue="1.80E-13"
                     /label="NRPS-te1"
                     /locus_tag="RHA1_ro02319"
                     /protein_end="2186"
                     /protein_start="2161"
                     /score="42.7"
                     /tool="antismash"
                     /translation="QPEGPYHLLGWSLGGVVAHAIAGAL"
     gene            7917..8981
                     /locus_tag="RHA1_ro02320"
     CDS             7917..8981
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033:iron compound
                     ABC transporter, periplasmic (Score: 270.2; E-value:
                     3e-82)"
                     /gene_kind="transport"
                     /locus_tag="RHA1_ro02320"
                     /note="GO_function: GO:0005381 - iron ion transporter
                     activity; GO_process: GO:0006827 - high affinity iron ion
                     transport"
                     /product="ABC Fe(3+) transporter, substrate binding
                     component"
                     /protein_id="ABG94126.1"
                     /transl_table=11
                     /translation="MKTSGRYWRRAGIVMIAATALFAGACSESNSDSTDAAGSVTGQAD
                     ASAFPVSIPSALGTAEITEAPERVVTIGWGSEDAALSLGVVPVAVQNMKSDTGTDDGLL
                     PWSRAKLEELDPNAEPTLLTASSKEMPYEQIAALDPDVILAVHSGVNQEQYDKLSAIAP
                     TVAYPERRWATSWEDQITTVGKALGRSAQAETLVTQTQDTLAQAKSQHPEFAGKTVAFG
                     SGTEPGSYNFYFDTDPRLKMLASLGFTVDPLAQQLRESSDQTKFAAPVSLELLPTYNPD
                     VLLAWYLSPELQNEVQSNPLFAGMKAVRDNAYVGLTDPPLVFASSSPNVLSVPWLLDKL
                     LPQLSQAANNAQAS"
     gene            complement(8998..10233)
                     /locus_tag="RHA1_ro02321"
     CDS             complement(8998..10233)
                     /codon_start=1
                     /experiment="microarray"
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 332.1; E-value: 7.8e-101)"
                     /gene_kind="transport"
                     /locus_tag="RHA1_ro02321"
                     /note="tc: 2.A.1; GO_component: GO:0016021 - integral to
                     membrane; GO_component: GO:0019866 - organelle inner
                     membrane; GO_function: GO:0005215 - transporter activity;
                     GO_process: GO:0006810 - transport"
                     /product="transporter, MFS superfamily protein"
                     /protein_id="ABG94127.1"
                     /transl_table=11
                     /translation="MTPLRTSREFRYIFIARTISIFGLGLLLVAVPLQVYDMTNSTLAV
                     GAASIVVGSSVFIGTLFGGVIADRYDRRPVISLARAAAGLAFAILAVNAFLPTPQLWII
                     YLCGVIEGLAGGISATALMAVIPSLLPKDKMAAAGALMTVMADLGTVASPAIGGVIIAA
                     TSVGTNYVLAAVSSGITAYCIARLPSLPPPVKNTESPLRSIASGFTYAAKDSVVGGTLL
                     VGFCAMMLTGWNVLLPAYASQVLHAGPAATGLLYSAPAVGALTGSLTSGWTGTARRGGL
                     IVFLAAMIASAGLIGVGAVPMIAVTFLGLAAHGFGRVLGDILRYAVIQTETPEECRGRV
                     AGVWGAQISTGSAAGALVAGAVGAAVGPREAFLLYGAGGIVVLAVLALTLKGLRTYSSA
                     AAEEDDLSAAAQ"
     gene            10415..10657
                     /locus_tag="RHA1_ro02322"
     CDS             10415..10657
                     /NRPS_PKS="Domain: PP-binding (11-72). E-value: 7.2e-13.
                     Score: 40.8. Matches aSDomain:
                     nrpspksdomains_RHA1_ro02322_PP-binding.1"
                     /codon_start=1
                     /experiment="microarray"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="RHA1_ro02322"
                     /product="probable isochorismatase"
                     /protein_id="ABG94128.1"
                     /sec_met_domain="PP-binding (E-value: 7.7e-14, bitscore:
                     40.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSASSTVPTRDRIRADVADVLDVPVAEIDDSANLLDEGMDSVRV
                     MALVERWRADGVQVDLVDLVGEPTLDAWFEVTAAR"
     aSDomain        10448..10630
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RHA1_ro02322_PP-binding.1"
                     /evalue="7.20E-13"
                     /label="RHA1_ro02322_PP-binding.1"
                     /locus_tag="RHA1_ro02322"
                     /protein_end="72"
                     /protein_start="11"
                     /score="40.8"
                     /tool="antismash"
                     /translation="DRIRADVADVLDVPVAEIDDSANLLDEGMDSVRVMALVERWRADG
                     VQVDLVDLVGEPTLDA"
     gene            10733..12076
                     /locus_tag="RHA1_ro02323"
     CDS             10733..12076
                     /codon_start=1
                     /experiment="microarray"
                     /locus_tag="RHA1_ro02323"
                     /note="GO_component: GO:0016021 - integral to membrane;
                     GO_function: GO:0003674 - molecular_function"
                     /product="conserved hypothetical protein"
                     /protein_id="ABG94129.1"
                     /transl_table=11
                     /translation="MAHETSGTGRMSVLRTPRFWIAPLLLVSVVMSLLAALYMGGMLNP
                     TKHLNHFPIALVNQDEGDTTPNSNPPQQQNFGDQIAAGLVEGVDPDKVELRQIGIAQAQ
                     SALDNGEIYGAIVIPSDFTKRTFILAQAGVIPGDVERPVITIYTNPRAGTISANLVQNI
                     GEMALDKANQTMGQQLTTQVTQQLQATAPDLQLSGASRLVLDDPIDVRVVAHNPLPDGT
                     GFGLAAFYYALLIVLAGFTGATIASTLIDGMLGFTPTEVGPLYLHNEAVPISRFNTLLI
                     KWAVMVVLAMIVSGLYLWISSALGLPITDPLALWEYGAFAIAAVGITAMSVMAAFGNLG
                     LLINLLVFVVLALPSSGGTIPLEAAPRLYTWLGEFEPMHQIYIGVRAIMFFGAAGDAGL
                     IHAVWMTLAGLLIGLVFGAVITRFYDRKGLHRRHKAQTEPEPVDAAGA"
ORIGIN
        1 atggccatcc cgcccatttc gacctacacg atcccggaga tccacgaggt ccccgaatcg
       61 aaggtgtcct ggcgcctcga cccccggcgt tccgcactgc tggtccacga catgcagaac
      121 tacttcatcg acgcgtacga cgtgcgtgcg gagccgatgt cgactgcgat ggcgaacatg
      181 gtccggatcc gcgaactgtg ctcggaagca ggaattcccg tgatctacac gatgcagccg
      241 ggcgaccagc acccgtcgcg tcgcggcatc ctcgccgact tctggggccc tggactgacg
      301 tcgggtcgcg acaccgaggt ggtcgagccg ctcgctcccc gcgagggcga catccaggtg
      361 accaaatggc ggtattcggc gttccagcgc accgacctcc ggcagttgct cggccaccac
      421 ggccgcgacc agctgatcgt cacgggcgtc tacgcgcaca tgggctgcat gctgagtgcc
      481 gccgaggcgt tcatgtcgga tgtgcagccg ttcctggtct ccgacgcgac tgcggatttc
      541 agccgtgacg aacacctcat ggccctcacc tacgcggcga agcgctgcgg ttcggtgacc
      601 accacggacg cgctggtctc ggcgctgtct ccactcgaag tcggttgaat cgacccgaag
      661 accccactcc ggcgcagcgc ttcgtcccga ggcgtgcgtc ggtgtgcgtc ggcagtcgga
      721 tccccacagc tcatgtggtt aggctaacct gacacgctga gtagctgaaa gcccgaaagc
      781 ccgagcccga aagccgaaag catcaggagt gcctgttaga tgtccctttc gatttcgttg
      841 ccgtccaccc tgcagaccgg ggaggacacg gccgatgtct gtttgaccgc cgcccagcgc
      901 gagctgtggt ccgggcacca gctcgacccg acccggtcgg ccttcaccac agccgaatac
      961 gtggaggtcg ccgcccccgt cgacatcgac gctctcgcgg cggcggtacg cacggtgatc
     1021 gaggaggccg agattctctc ggtccgcttc gaggccgaac ccggtgccga ttcggccgac
     1081 gtcgtccagg tgcacgatcg tcgccacgcc cccgaactcg aacgtctcca actcgaccgg
     1141 gccgccgccc tggagtggat gcgtgaggac gtgcgccgac cgctcgactt cgactccgct
     1201 cccctcgtcc gcacggcact gatcacgacc gaatccggtg tgctctggta cctccgcgcc
     1261 ccgcacgcgt tgctcgacgc ctacgggtat tcgctgctca cccgccgcgt cgcggcgctg
     1321 tacgcggccc ggctcgcggg caccgaaccc cggccggcca agttcccgcc gttgcggacg
     1381 cacgtccagg ccgcacggga attcgatgcc gcggccccgg acagcgcgcc gcagtcggct
     1441 tcgcatccgg tcggattcag cgacacggtg cgccggcccg tccccgaccc ccgtcggtac
     1501 acgatcccga tcgaccccga cgtcgcgagg agcctgcgcg aggcggccac cgcgcaggcg
     1561 accacgtggg cggaagcggt gtacgcggcc gctgccacat acctgggcgc ccacacggga
     1621 gccgaggagg tgacgctccg ggttccggtg ctcgcccgca acgggatcga gctggcgtcg
     1681 cccgtgacgg ccacgaacat tgtgccgctc cgcattccgc tcgacgcacg gtcgacgttc
     1741 gccgacgtga tcggcagggt ggccgccgca tggtccgaga cacgtccgtt ccagcgcgtc
     1801 cgggaggcag gcagacgcgc caccggcgga gcggtggtga acgtcaaacc gttcgccggc
     1861 agaatcgctt tcggtcccac cttcggcgcg gtgcatcaac tcgcgaccgg tccggtggag
     1921 gacgtggtca tctccgtctc gggcgccggc gacgagctca cgctcgaatg ggccggaaat
     1981 cccgacgtct acacggacga cgagatccgg caccacgcac accgattcgc gcactacctc
     2041 cgaaccatct ccgtggcagc agaacccgtc tccgtggtcg acgtctgcgc tccggacgaa
     2101 ctgcacctgt ggcggtccgc ggccggcctc gaccggacca ccggcacggc agcgaccctt
     2161 ccggacaaca tcgtctccgc cttcctcgcc caggcgcgca cccacccgga ccgcgtcgcc
     2221 gtgaacgatc tgtcctaccg tgaactctcg actcgcagcg ccgccctggc ccggcagctg
     2281 aggtcggccg gcgccggccg cggcacggtc gtggccgtca gcctcccccg cggcaccgac
     2341 ctgatcgtcg ccgtcctcgc gattctccgc agcggcgcca cgtacctgcc gatcgatccg
     2401 tcgtccccgg ccgaacgcgc gcggttcatc ctgcgggatg cgcagccgtc gctgggaatc
     2461 ggatccgccg acctgctcgg cgacctcccg cgagtcgagg aggactcggc acagtccgcg
     2521 tccggcgaac tcgacaacgc cgtgcaggcg gacgacatcg cgtacgtcat ctacacgtcc
     2581 ggatccaccg gtgtccccaa gggcgttccg attccgcacc gtaacgtgat gcggttgttc
     2641 gacgtgtccc gcgaatggtt cacgttcacc gaggacgact gctggcccct gctgcactcg
     2701 tacgcgttcg acttctccgt ctgggagatc tggggtgcgc tgctgcacgg cggccgcctc
     2761 gtcacggtcg acgaggccac cctgacgtca ccggccgacc tcgccgggct cctcgtcgac
     2821 gagggtgtca cggtgctgaa ccagacgcct tccgcgttcg ggcatctcgt cgacgctctc
     2881 gtccgcgcgg actcgttcga ccggctgcga ctgcggtacg tcgtgttcgg cggtgaggct
     2941 ctcgatcccg ccgtcctgcg cgcctggttc gccgcgaccg gtccggatga gggggccgaa
     3001 ctggtcaaca tgtacgggat caccgagacc accgtgcacg tcaccgccac gaaagtcacc
     3061 gcagccgacg tggtggacat cggggttccg ctcggcgacc tccgcacgta cgtcctcggg
     3121 ccggggctgc gtccggtgcc gcccggcgtg accggcgaga tctacgtgtc cggccccgga
     3181 ctgtccccgg gctacctcgg gcgtcccgac ctgacgtcgg gacggttcgt cgccgacccg
     3241 ttcgcccccg gcggcacgcg catgtaccgc accggcgacc tcgcacggta cgacgcgacc
     3301 ggcacgctcc actaccacgg ccggatcgac gaccagatcc aattgcgcgg ttaccgtgtc
     3361 gaactcggcg agatcggtgc cgcgatgacc gcggtgcccg acgtgcaggc ggcggtggcc
     3421 acggcgcacg agcaggccgg cggcgaccag cggatcgtcg gatacgtcgt tccccgtccg
     3481 ggcggcgagc acgacgccgt cgaggagcag gtgcgggcgc acctggtccg ctcccttccc
     3541 gggtacatga cgccgtccgc actggtgatg ctcgaccgat tgccgttgac ccacaacggc
     3601 aaggtcgaca aggacgcgct gcccgccccc cgttggctcg gacaggccgg cgacacaccg
     3661 cggaccgaca ccgaagcccg gatcctcccg ctgttcacct cggtgctcgg cgccgagcag
     3721 gtcggtgtcc acgacgactt cttcgcactc ggcgggaact ccctcctcgc cgccgctctc
     3781 gtgtccgcga tcaccgcgga actggccgtg ccactgcggg ttgccacggt cttcgagaat
     3841 cccaccgtgg ccgccgtggc cgcgcaactg gaggacgccg gcgagcgggt atcggcgagc
     3901 aggccgtccc cgcgggacct ccctgagggc acgccggtgc cgctgtcacc cgcgcaggaa
     3961 cgtctgtggt tcctcgacag cgccgccggc ggcggaacgt acctgctggc acttgccgtc
     4021 gacttcgggg aaggcctcga acccgacgcc ctgtccgcgg cgctcgggga cgtcgtgacc
     4081 cggcatcagt cgttgcggac ggtgttcccc ctcgtcgact cggtacccca ccaggtcgtg
     4141 cttcccgccg gagatgcgaa ggttcggctc gaacgtgtcg acaacgtcgg caacatcgag
     4201 gggcacatcg cggcgatgac gacggtgggt ctcgggctca ccgaccagcc gccgctgcgc
     4261 gcggtgctgt acgaaccgca gcacacgctg gtcctgttgc tgcaccacat catcggcgac
     4321 gagtggtcgc agtcgagact gctggacgac ctcgccttcg cgtacaacgc ccgccgcgcc
     4381 ggacgggcac cggagttcac gccgctgccg ttgcagtacc cggacgtcgc cgtgtggcaa
     4441 cgcgaacgca tcggcgccgg cgacgacgcg accccgttgc tgaccggcca actcgactac
     4501 tggcgtgagc aactcgccgg tctgccgctc gaactgggct ggcgcaccga ccgaccccga
     4561 ccggccctgc ccaccaaccg tggcgcaagc gttcaccgca cgctgtcgcc gtcgctgcac
     4621 gcggccgtcg agtcgctcgc cgccgagcgc cgcgcgagct tcttcatgat cgtccacgcc
     4681 gccgtggccg tgctgctcga aaggctgggc gccggcgagg acatcgccct cggcgtgccc
     4741 gtcgccggtc gcagtcaccc cgacctcgac gccatggtgg gctgcttcat caacacggtg
     4801 gtcctgcgga ccgacgtctc gggcgacccg acgttcgacg acctgctgga tcgggtcagg
     4861 gccgtcgacc tcgacgccgt cgactacgcc gacgtgccct tcaaccgtat cgtcgaactc
     4921 gtcaatcccc cacggtcgtc ggcccgccac ccgctgttcc aggtgatgtt gtcgcactgg
     4981 aagcaggacg gcgcggcggc gcgattcgac gggacgaccg ccgcggtgcg gatgctcgac
     5041 gcgacgtccg cgaaattcga tctggcgctg cgcttccagg aacgcccgga cagcggcggg
     5101 gtcgacgtga cgttcgagta ctccaccgaa ctcttcgatg ccgcgaccgt cgaatccttc
     5161 gcggaccgcc tcgccgtggt gatcgagcgg ctcgtcgcga accacgagca gcggatcgcc
     5221 cgggtcgaca tcctgacccc gcaggagcgg ggccgagtgc tcggcgaatg gtcccatgcg
     5281 gagcactccg ttccggcccg caccttcgac gagtacttct cggcgcaggt ggcggagaca
     5341 cccgacgccg aggctctcgc cgtcggcgcg agcgtgcggc ccgcggtctc cctcacgtac
     5401 cggcagctcg acgagcgggc gaaccggatt gcccacctgc tgatctcgcg tggcgcgggc
     5461 cccggtgacg tggtcgcgct cgcactcgac cggtccgccg agctgatcat cagcgttctc
     5521 gccgtgttga aaagcggtgc cgcgtacctt cccgtcgatc ccacgtaccc ggccgaccgg
     5581 atcgcgcaca tgctcgccga cggcgcaccg gtcgcgatcc tcacgtcttc cgtcggtgtg
     5641 cccgaccgca ccccgctggg caccgacgtg cccattctcg acctggacga tccgggcctg
     5701 cagtccctgc tcgacaccca gccggtcacg gcccccaccg acgcggaccg gagcaggccg
     5761 ctgaaactcg acgacgccgc gtatctcatc tacacgtccg gatcgacggg ggtgccgaag
     5821 ggggtcgtcg tcccccaccg gggcatcgcg gacctgctgt cgctgcagtc ggacgtgatc
     5881 ggcatggacc acaccactcg ggcgctccac ttctcgtcca tcagcttcga cctcgcgttc
     5941 tggcagatca tgtggggtgt gctctcgggc ggaacactgg tggtcgcgac ggacgccgac
     6001 cgcatcccgg gtgagccgct cgcccgggtc atcaacgaac acgacgtgaa cttcgtcggc
     6061 gtgccaccgt ctttcgccgc cgccttcccg ccggagcatc ccattccgga cggcgtcgac
     6121 ctgatgctcg gcgccgagaa gctcacaccc cagctgatcg agcggtacgc ccccggccgc
     6181 cggctgttca acgcgtacgg tcccaccgag tgcacggtca acgccacgct tgccctcgtg
     6241 gaaccggggc acgaaggtcc ggtccccatc ggcgtcgtcg atccgggcaa gcacgcctac
     6301 gtcctggacc acgcgctgcg gccggtgcct ccgggtgtgt ccggcgagct gtatctcgcg
     6361 ggcgacagcg tcacccgggg ataccgcaac cagagtccca agacggcgga acgtttcatc
     6421 gccgaccctt tcgcggtgcc gggcagtcgc atgtaccgga cgtcggatgt ggtgtggtgg
     6481 ggccgggacg gtcagatcta tttcaccggc cgcgccgact cgcaggtcaa ggtgcgcgga
     6541 ttccgcatcg aactcaacga gatcgaggcg gtgctgtccg gtgacccgga cgtcgagcac
     6601 atcgtcgtcg tggtccgtga ggaccgcccg ggcgatcagc gactggtcgc gtacgcgacg
     6661 tcggtgccgg gcggccggat cgaccccgac cagttgcacc gtcgtgccgc cagcaggctg
     6721 ccggactaca tgattccggc cgcgttcatc gccgtcgacg agttccccac cctccccaac
     6781 ggcaagctcg accagacgtc gcttcccgtt ccgcacctgt cactgcaggt gtccgagcgg
     6841 gggccgcgca ccgcgcgcga agaggtgctg tgccagttgt tcgccgaggc tctcggtatc
     6901 gagcgggtcg gcatcgacga cagcttcttc gacctcggtg gccactcgct gatggcggcc
     6961 ggattgatga gcgcgatctc gaagcggctg tccgtgaccg cgaccgtggc ctcgctcttc
     7021 gcggcgccga ccgtggccca gctggcaggc cgtctcgacg acgatcacga cgccgacgcg
     7081 ctggccgtcc tgctgccgtt ccgcaccgag gggtccaagc caccggtgtt ctgcttccac
     7141 cccgcaggcg gaatcagctg gggctactcg gggttgctgc ggcacatcga cgacgactac
     7201 ccgctgtacg gcgtgcaggc ctccaacctg tcgacgtccg agcggccgcc ggaaacgctc
     7261 gaggacatgg cggccgagta catcgagcac atgcggaccg tgcagcccga gggcccctac
     7321 cacctcctcg gatggtcgct gggcggcgtc gtcgcgcacg ccatcgccgg tgcgctgcag
     7381 aaccagggtg aggaactcgg catgctcgtc atgctcgact ccttcccgtc ggacgcgtgg
     7441 gcctcgatgc cgacggaaca ggacgcgctc gccgcgctgc tctacatggt cggctacgac
     7501 cccgagccgc tgctcgcctc cgacaccgag ccgcaccgcg gcggcggcct ggaccggcag
     7561 caggtgatcg acatcctgcg cggcgaaggc agtgcgctcg ccgggatcaa cgagcacacc
     7621 ccggcagcga tgatcgacaa cttcgcgaac gccgtgcgcc tcgaatccga accctcacag
     7681 atcgtcgtgg actccgacat gctcttcttc actgcggcta ggaatcccgc gaccgcggcg
     7741 acgtacgacc tgtggcggcc ctacctgacc ggcaccatcg tcaaccacga cctcgactgc
     7801 gagcacaagg acatgaccca gccccgttgg atcggcgaag tcggctccgt cgtgaacgag
     7861 gccctcgcct cgttcggctc gcgcatgaac cccatcaaca cagaacaggg agatcgatga
     7921 aaacgtccgg aagatactgg cgtagagccg gaatcgtgat gattgcggca accgcgctgt
     7981 tcgcgggtgc ctgcagcgag tcgaattccg actcgaccga cgcggcggga tccgtcaccg
     8041 gacaggccga cgcgtcggcc ttccccgtgt cgattccgtc ggcgctcggt accgccgaga
     8101 tcacggaggc accggaacgc gtcgtcacga tcggctgggg cagcgaggac gcggcactgt
     8161 cgctcggcgt cgtgcccgtc gccgtgcaga acatgaagtc ggacacggga accgacgacg
     8221 gcctgctgcc gtggtcgcgg gcgaagctcg aagagctcga cccgaacgcg gaacccacgt
     8281 tgctgacggc gtcgagcaag gagatgccgt acgagcagat cgcggcactc gaccccgacg
     8341 tcatcctggc tgtccactcg ggcgtgaacc aggagcagta cgacaagctc tcggccatcg
     8401 cccccaccgt ggcgtacccg gagcgtcgct gggccaccag ctgggaagac cagatcacca
     8461 ccgtcggcaa ggccctcggc cggtccgcac aggccgagac actggtgacc cagacgcagg
     8521 acaccctcgc gcaggcgaag tcgcagcacc ccgagttcgc cgggaagacg gtggcattcg
     8581 gtagcggcac cgagccggga tcgtacaact tctacttcga caccgatcct cgcctgaaga
     8641 tgctggccag cctcggtttc acggtcgacc cgctcgccca gcagttgcgc gagagcagtg
     8701 accagaccaa gttcgcggct cccgtcagcc tggaactgct gccgacgtac aacccggacg
     8761 tgctgctcgc gtggtacctg tcgcccgagc tgcagaacga ggtccagtcg aacccgctgt
     8821 tcgccgggat gaaggccgtg cgtgacaacg cctacgtggg tctgaccgat ccgccgctgg
     8881 tgttcgcgtc gagctcgccg aacgtgctca gcgtgccgtg gctgctggac aagctgctcc
     8941 cgcagctgtc gcaggccgcg aacaacgctc aggccagcta gttcccacct gagcgcgtca
     9001 ctgtgccgct gccgagaggt cgtcctcctc ggcagcggca ctgctgtagg tgcgcaaccc
     9061 cttcaaggtc agcgcgagaa ccgcaagcac cacgatgccg cccgccccgt agaggaggaa
     9121 cgcctcacgc ggacccaccg cggctccgac ggcgccggcg acgagcgctc cggcagccga
     9181 gcccgtggag atctgggcgc cccacacacc ggcgacgcgt ccgcggcatt cctcgggcgt
     9241 ctcggtctgg atgacggcgt accggaggat gtcaccgagg acgcggccga atccgtgtgc
     9301 ggcgagcccg aggaacgtga ccgcgatcat cgggacggcg ccgacgccga tcagcccggc
     9361 cgacgcgatc atggccgcga ggaacacgat caggccaccg cgacgagcag ttcccgtcca
     9421 gccgctcgtg agtgatccgg tgagggcgcc gacggcgggg gcgctgtaga gcagtccggt
     9481 cgccgccggt ccggcatgga ggacctggct cgcgtaggcg ggcagcagca cgttccagcc
     9541 ggtcagcatc atggcgcaga acccgaccag cagcgtcccg ccgacgacgg agtccttggc
     9601 ggcataggtg aagccgctgg cgatcgaccg cagcggactc tcggtgttct tgaccggcgg
     9661 cggcagcgag ggcagccggg cgatgcagta cgcggtgatt cccgaggaca ccgcggccag
     9721 aacgtagttg gtgcccacgg atgtcgccgc gatgatcaca ccgccgatgg caggcgacgc
     9781 gaccgtgccg aggtcggcca tcacggtcat cagggcaccg gcggcggcca tcttgtcctt
     9841 ggggagcagc gacgggatca ccgccatcag cgcggtcgcg gagatgccgc cggcgaggcc
     9901 ctcgatcacg ccacagaggt agatgatcca caactggggt gtgggcagga acgcgttgac
     9961 cgcgaggata gcgaaggcca gacccgctgc ggcacgggcg agggagatga ccggcctgcg
    10021 gtcgtaccgg tcggcgatca cgccgccgaa cagggtgccg atgaacaccg aggagcccac
    10081 gacgatgctc gccgcgccca ctgccagtgt ggaattcgtc atgtcgtaca cctgcagcgg
    10141 cactgccacc agcagcagac ccagaccgaa gatggagatc gtgcgggcaa tgaagatgta
    10201 tcggaactcg cgactcgtcc gtagaggcgt caagtcgatt gcgtatcgcg ataatccggc
    10261 cattgtcatc cattcacatt cggttgcaac agctctccgt ttcgccgttc gcgtggagag
    10321 caactatgct taggcttcac taacccagca acctacccca tgtcgtcgaa tcggctcaac
    10381 gggccgtggt tcgacgccgc accggaggat gacagtgagt tccgcttcca gcacagttcc
    10441 gacccgcgac cgaatccgcg ccgacgtagc cgacgtgctc gacgtcccgg tcgccgagat
    10501 cgacgattcc gcgaacctgc tcgacgaggg aatggactcc gtgcgcgtga tggcgctggt
    10561 cgaacgatgg cgggcggacg gtgtgcaggt ggatctcgtg gacctcgtcg gcgagccgac
    10621 actcgacgcc tggttcgagg tgacggcagc acgctgagcg gtcccaccgc ctactcttga
    10681 tcccgctggt cgatcccagg gtcggcccgg acacgggagg atgcgagggg acatggctca
    10741 cgaaaccagc ggtacaggca ggatgagcgt gctccggaca ccccggttct ggatcgctcc
    10801 cctgctcctc gtctccgtcg tcatgtccct gctggccgcg ctgtacatgg gtggaatgct
    10861 caaccccacc aagcacctca accacttccc catcgcgctc gtcaatcagg acgagggcga
    10921 caccacaccc aattccaacc cgccgcagca gcagaatttc ggcgaccaga tcgccgccgg
    10981 gctcgtcgag ggtgtcgatc cggacaaggt cgaacttcgg cagatcggga tcgcgcaggc
    11041 ccagtccgcg ctggacaacg gggaaatcta cggcgcgatc gtcataccga gcgacttcac
    11101 gaagcgcacg ttcatcctcg cccaggccgg cgtgattccc ggagacgtcg agcgtccggt
    11161 gatcacgatc tacacgaacc cccgcgcagg cacgatcagt gcgaacctcg tccagaacat
    11221 cggtgagatg gcgttggaca aggccaatca gacgatgggc cagcagctca ccacccaggt
    11281 gacgcagcaa ctccaggcga cagcccccga cctccagctg tcgggggcca gccggctcgt
    11341 gctcgacgac cccatcgacg tgcgggtcgt ggcccacaac ccgctgcccg acggcaccgg
    11401 tttcggcttg gcggcgttct actacgcgct cctgatcgtc ctggccggtt tcaccggtgc
    11461 gaccatcgcg agcaccctca tcgacggcat gctcggattc actccgaccg aggtcgggcc
    11521 gctgtacctc cacaacgagg cggtcccgat ctcacggttc aacaccctgc tgatcaagtg
    11581 ggcggtgatg gttgtgctgg cgatgatcgt gtcaggtctg tacctctgga tcagctccgc
    11641 cctcggcctg ccgatcaccg acccgctcgc cctgtgggag tacggcgcct tcgcgatcgc
    11701 cgcggtcggg atcacggcga tgtccgtgat ggccgcgttc ggcaacctgg gcctgctcat
    11761 caacctgctg gtgttcgtcg tcctggcgct gccctcgtcg ggcggcacga tcccgctcga
    11821 ggcggcgccg cgcctgtaca cctggctcgg tgagttcgaa ccgatgcacc agatctacat
    11881 cggggtgcgc gcgatcatgt tcttcggcgc agcgggcgac gcagggctca tccacgcggt
    11941 gtggatgacc ctcgccggcc ttctcatcgg cctcgtcttc ggcgccgtca tcacccggtt
    12001 ctacgaccgc aagggtttgc atcgccgcca caaggcgcag accgaacccg aaccggtgga
    12061 cgcggccggg gcgtga
//
