BGC0000417 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000417 (Rhodococcus jostii RHA1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	12,076	rhodochelin	NRPS:Type I	100%

BGC0000417 - Region 1 - NRPS

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Location: 1 - 12,076 nt. (total: 12,076 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 12,077
Label		BGC0000417

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000417	1.00	NRP	rhodochelin	Rhodococcus jostii RHA1
BGC0002075	0.32	NRP, Alkaloid	pyreudione A, pyreudione B, pyreudione C, pyreudione D, pyreudione E	Pseudomonas fluorescens
BGC0001833	0.28	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001132	0.28	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001825	0.28	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0000343	0.27	NRP	enterobactin	Pseudomonas sp. J465
BGC0001149	0.27	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001128	0.27	NRP	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000457	0.26	NRP	vicibactin	Rhizobium etli CFN 42
BGC0002286	0.26	NRP	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000417	1.00	NRP	rhodochelin	Rhodococcus jostii RHA1
BGC0002075	0.65	NRP, Alkaloid	pyreudione A, pyreudione B, pyreudione C, pyreudione D, pyreudione E	Pseudomonas fluorescens
BGC0001833	0.61	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001132	0.61	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001825	0.61	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0000343	0.61	NRP	enterobactin	Pseudomonas sp. J465
BGC0001149	0.60	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001128	0.60	NRP	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000457	0.60	NRP	vicibactin	Rhizobium etli CFN 42
BGC0002286	0.59	NRP	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 12076:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Thr - Fo-OH-Orn)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

RHA1_ro02319

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AMP-binding (454..843): Thr

nrpys: Thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
Small clusters prediction:: thr (Thr)
Single AA prediction:: thr (Thr)

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNVGMVHK
Nearest Stachelhaus code(s):: Thr DFWNVGMVHK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1499..1906): Fo-OH-Orn

nrpys: Fo-OH-Orn

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DLWGMGAVNK
Nearest Stachelhaus code(s):: Fo-OH-Orn DLWGMGAVNK (100% 8Å match)
Stachelhaus code match:: 100% (strong)