LOCUS       BGC0000426             11658 bp    DNA     linear   BCT 04-NOV-2013
DEFINITION  Paenibacillus larvae strain DSM 25430 SevA (sevA) and SevB (sevB)
            genes, complete cds.
ACCESSION   BGC0000426
VERSION     BGC0000426
KEYWORDS    .
SOURCE      Paenibacillus larvae
  ORGANISM  Paenibacillus larvae
            Bacteria; Firmicutes; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 19:14:07
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            1..3243
                     /gene="sevA"
     CDS             1..3243
                     /NRPS_PKS="Domain: AMP-binding (27-417). E-value: 2.8e-110.
                     Score: 360.5. Matches aSDomain:
                     nrpspksdomains_sevA_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (525-589). E-value: 1.2e-22. Score:
                     71.7. Matches aSDomain: nrpspksdomains_sevA_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (602-904). E-value:
                     1.6e-141. Score: 464.4. Matches aSDomain:
                     nrpspksdomains_sevA_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (908-1069). E-value: 7.3e-42.
                     Score: 134.6. Matches aSDomain:
                     nrpspksdomains_sevA_TIGR01720.1"
                     /codon_start=1
                     /gene="sevA"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     347.9; E-value: 1.3e-105)"
                     /gene_kind="biosynthetic"
                     /product="sevA"
                     /protein_id="AGZ03650.1"
                     /sec_met_domain="Condensation (E-value: 1.9e-80, bitscore:
                     257.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.9e-119, bitscore:
                     385.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.1e-15, bitscore:
                     44.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKQRNSISRQPYEHQFAYCGLPIHELFEQQVDRNPDQTAVVFKN
                     EQVTYRQLNERANQLAGVLMARKVTTDTVVAIMLEKSVEMIVSILAVLKAGGCYLPIDI
                     DYPGNRIQYMLSDSQAKILITTKEISQNIRFEGEHVLLYDDSIWHFPKENPNVKIQVTD
                     LAYVIYTSGTTGQPKGVMVEHKGIANLKVVWEESFGISPRDRIGFFASISFDASVWEIF
                     MALLNGATLYVLSKELLSNLCEFQNYLGENSITVMTLPPSYAQYLDPVSLFDLRLLITA
                     GSAPSQSLVNKWNQIVTYVNAYGPTETSICATNWIAPREWCNASHIPIGTPIRNTQVYI
                     LDDNLQPVATGESGQLWVGGVGLARGYLNRPELTAEKFIDNPFIPGEKLYCTGDYARWL
                     SDGNIEYRGRMDHQVKIRGYRIELGEIEAVLQKHSGISEAAVLVKKDKLGNPFLSAYYV
                     AEKEIPGHLLRSYMENELLHYMVPYHFYCIENMPLTVNGKVDREKLLLPEYNQETSSKY
                     TAPRNELELLLAEVWKDVLEVEEVGIDDNFYLLGGDSIKAIQMASKLYEHQLRLDMKDL
                     MMNPTISTLAPVVAFIEQECDQGIVQGEVPLSPFQHWFFKKQFTAMHHWNQSVLLYNPE
                     GYNQDILQTVLMKLIEHHDALRMVYTLDDSFPTQINRGIEGNLLGFSTFDVSGQTDAGQ
                     FIHHEIKRLQSRMDLSQGPLVQAGLFRTAEGDHLFLAIHHLVMDGVSFRILLEDLSKTY
                     EQAMHGELVVLPSKTDSYQTWTTRLLEYSASGEFLKEIPYWKEFERKVSSVPLPKDKTA
                     SEHKEKDKRSIQLELTGEQTQQLLKDVHRAYHTEINDILLTALGLTIHGWTGQKQVLLN
                     LESHGRHDILKGVNISRTVGWFTSQCPVILDMSYADDVSHEIKVVKENIRKIPNQGIGY
                     EMLQYLTPAEMRSGLSFSPEPEICFNYLGQLDKGMNSERFAQSPYSNGASLGPDGEGNI
                     GEENELYFPLFLTSYIQHGRFQLVISYRGKQYHQSTMAHVANLYKQQLLNVMDHCLKKE
                     NAERTPNDFTCSNLELKELDQVYALLEQSLNQ"
     source          1..11658
                     /culture_collection="DSM:25430"
                     /db_xref="taxon:1464"
                     /isolation_source="honey"
                     /mol_type="genomic DNA"
                     /note="genotype: ERIC II"
                     /organism="Paenibacillus larvae"
                     /strain="DSM 25430"
     protocluster    1..11658
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:11658]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..11658
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..11658
                     /SMILES="NC(Cc1ccccc1)C(=O)NC([*])C(=O)NC(Cc1ccc(O)cc1)C(=O
                     )O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..11658
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000426"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..11658
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     aSDomain        82..1251
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sevA_AMP-binding.1"
                     /evalue="2.80E-110"
                     /label="sevA_AMP-binding.1"
                     /locus_tag="sevA"
                     /protein_end="417"
                     /protein_start="27"
                     /score="360.5"
                     /specificity="consensus: phe"
                     /tool="antismash"
                     /translation="FEQQVDRNPDQTAVVFKNEQVTYRQLNERANQLAGVLMARKVTTD
                     TVVAIMLEKSVEMIVSILAVLKAGGCYLPIDIDYPGNRIQYMLSDSQAKILITTKEISQ
                     NIRFEGEHVLLYDDSIWHFPKENPNVKIQVTDLAYVIYTSGTTGQPKGVMVEHKGIANL
                     KVVWEESFGISPRDRIGFFASISFDASVWEIFMALLNGATLYVLSKELLSNLCEFQNYL
                     GENSITVMTLPPSYAQYLDPVSLFDLRLLITAGSAPSQSLVNKWNQIVTYVNAYGPTET
                     SICATNWIAPREWCNASHIPIGTPIRNTQVYILDDNLQPVATGESGQLWVGGVGLARGY
                     LNRPELTAEKFIDNPFIPGEKLYCTGDYARWLSDGNIEYRGRMDHQVKIR"
     aSModule        82..3207
                     /complete
                     /domains="nrpspksdomains_sevA_AMP-binding.1"
                     /domains="nrpspksdomains_sevA_PCP.1"
                     /domains="nrpspksdomains_sevA_Epimerization.1"
                     /domains="nrpspksdomains_sevA_TIGR01720.1"
                     /locus_tags="sevA"
                     /monomer_pairings="phe -> D-phe"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       268..309
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevA_0001"
                     /evalue="2.40E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="sevA"
                     /protein_end="103"
                     /protein_start="89"
                     /score="17.5"
                     /tool="antismash"
                     /translation="LAVLKAGGCYLPID"
     CDS_motif       493..552
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevA_0002"
                     /evalue="2.20E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="sevA"
                     /protein_end="184"
                     /protein_start="164"
                     /score="35.4"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGQPKGVMVEH"
     CDS_motif       1051..1134
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevA_0003"
                     /evalue="3.10E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="sevA"
                     /protein_end="378"
                     /protein_start="350"
                     /score="48.2"
                     /tool="antismash"
                     /translation="GESGQLWVGGVGLARGYLNRPELTAEKF"
     CDS_motif       1216..1281
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevA_0004"
                     /evalue="3.80E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="sevA"
                     /protein_end="427"
                     /protein_start="405"
                     /score="38.1"
                     /tool="antismash"
                     /translation="YRGRMDHQVKIRGYRIELGEIE"
     aSDomain        1576..1767
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sevA_PCP.1"
                     /evalue="1.20E-22"
                     /label="sevA_PCP.1"
                     /locus_tag="sevA"
                     /protein_end="589"
                     /protein_start="525"
                     /score="71.7"
                     /tool="antismash"
                     /translation="LLLAEVWKDVLEVEEVGIDDNFYLLGGDSIKAIQMASKLYEHQLR
                     LDMKDLMMNPTISTLAPVV"
     aSDomain        1807..2712
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sevA_Epimerization.1"
                     /evalue="1.60E-141"
                     /label="sevA_Epimerization.1"
                     /locus_tag="sevA"
                     /protein_end="904"
                     /protein_start="602"
                     /score="464.4"
                     /tool="antismash"
                     /translation="GEVPLSPFQHWFFKKQFTAMHHWNQSVLLYNPEGYNQDILQTVLM
                     KLIEHHDALRMVYTLDDSFPTQINRGIEGNLLGFSTFDVSGQTDAGQFIHHEIKRLQSR
                     MDLSQGPLVQAGLFRTAEGDHLFLAIHHLVMDGVSFRILLEDLSKTYEQAMHGELVVLP
                     SKTDSYQTWTTRLLEYSASGEFLKEIPYWKEFERKVSSVPLPKDKTASEHKEKDKRSIQ
                     LELTGEQTQQLLKDVHRAYHTEINDILLTALGLTIHGWTGQKQVLLNLESHGRHDILKG
                     VNISRTVGWFTSQCPVILDMS"
     CDS_motif       1945..1977
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevA_0005"
                     /evalue="1.90E-03"
                     /label="Cy2"
                     /locus_tag="sevA"
                     /protein_end="659"
                     /protein_start="648"
                     /score="10.9"
                     /tool="antismash"
                     /translation="LIEHHDALRMV"
     CDS_motif       2182..2247
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevA_0006"
                     /evalue="5.30E-11"
                     /label="NRPS-E2"
                     /locus_tag="sevA"
                     /protein_end="749"
                     /protein_start="727"
                     /score="34.7"
                     /tool="antismash"
                     /translation="LFLAIHHLVMDGVSFRILLEDL"
     CDS_motif       2653..2703
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevA_0007"
                     /evalue="1.10E-07"
                     /label="NRPS-E5"
                     /locus_tag="sevA"
                     /protein_end="901"
                     /protein_start="884"
                     /score="24.0"
                     /tool="antismash"
                     /translation="NISRTVGWFTSQCPVIL"
     aSDomain        2725..3207
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sevA_TIGR01720.1"
                     /evalue="7.30E-42"
                     /label="sevA_TIGR01720.1"
                     /locus_tag="sevA"
                     /protein_end="1069"
                     /protein_start="908"
                     /score="134.6"
                     /tool="antismash"
                     /translation="VSHEIKVVKENIRKIPNQGIGYEMLQYLTPAEMRSGLSFSPEPEI
                     CFNYLGQLDKGMNSERFAQSPYSNGASLGPDGEGNIGEENELYFPLFLTSYIQHGRFQL
                     VISYRGKQYHQSTMAHVANLYKQQLLNVMDHCLKKENAERTPNDFTCSNLELKELDQ"
     CDS_motif       2746..2808
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevA_0008"
                     /evalue="1.10E-07"
                     /label="NRPS-E6"
                     /locus_tag="sevA"
                     /protein_end="936"
                     /protein_start="915"
                     /score="24.1"
                     /tool="antismash"
                     /translation="VKENIRKIPNQGIGYEMLQYL"
     CDS_motif       2851..2880
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevA_0009"
                     /evalue="5.20E-03"
                     /label="NRPS-E7"
                     /locus_tag="sevA"
                     /protein_end="960"
                     /protein_start="950"
                     /score="9.4"
                     /tool="antismash"
                     /translation="PEICFNYLGQ"
     aSDomain        3268..3357
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sevB_NRPS-COM_Nterm.1"
                     /evalue="1.10E-17"
                     /label="sevB_NRPS-COM_Nterm.1"
                     /locus_tag="sevB"
                     /protein_end="30"
                     /protein_start="0"
                     /score="54.8"
                     /tool="antismash"
                     /translation="MTFQKEHVQDIYPLSPMQEGMLFHSLEDTK"
     gene            3268..11658
                     /gene="sevB"
     CDS             3268..11658
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-30). E-value: 1.1e-17.
                     Score: 54.8. Matches aSDomain:
                     nrpspksdomains_sevB_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (8-307). E-value:
                     1.9e-110. Score: 360.5. Matches aSDomain:
                     nrpspksdomains_sevB_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (470-870). E-value:
                     4.6e-117. Score: 382.9. Matches aSDomain:
                     nrpspksdomains_sevB_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (977-1043). E-value: 2.9e-20. Score:
                     64.1. Matches aSDomain: nrpspksdomains_sevB_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1055-1355). E-value:
                     9.9e-155. Score: 508.1. Matches aSDomain:
                     nrpspksdomains_sevB_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1360-1511). E-value: 6.2e-47.
                     Score: 151.1. Matches aSDomain:
                     nrpspksdomains_sevB_TIGR01720.1"
                     /NRPS_PKS="Domain: Condensation_DCL (1522-1822). E-value:
                     5.4e-108. Score: 352.4. Matches aSDomain:
                     nrpspksdomains_sevB_Condensation_DCL.2"
                     /NRPS_PKS="Domain: AMP-binding (1987-2381). E-value:
                     1.5e-119. Score: 391.0. Matches aSDomain:
                     nrpspksdomains_sevB_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2488-2557). E-value: 2.5e-16.
                     Score: 51.5. Matches aSDomain: nrpspksdomains_sevB_PCP.2"
                     /NRPS_PKS="Domain: Thioesterase (2580-2777). E-value:
                     2.2e-30. Score: 98.6. Matches aSDomain:
                     nrpspksdomains_sevB_Thioesterase.1"
                     /codon_start=1
                     /gene="sevB"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     277.1; E-value: 5.4e-84)"
                     /gene_kind="biosynthetic"
                     /product="sevB"
                     /protein_id="AGZ03651.1"
                     /sec_met_domain="Condensation (E-value: 2.7e-85, bitscore:
                     273.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 7.3e-130, bitscore:
                     420.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1e-15, bitscore:
                     45.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFQKEHVQDIYPLSPMQEGMLFHSLEDTKSGAYFVQVVTSVYGE
                     LEPELLMKSFKRLVQRHDVLRTTFLYDNLKEPLQIVLSERPLDMCMKRLDGSSNEIKNE
                     WISQFLKQDREKGFDITMDSLIRLALLETGGGEWTIVLSFHHILMDGWCSDLIFNELFR
                     IYDSLKQGAAVEWSPAQPYSQYIKWLEKQDKEAAARYWKTYLNGYEPMARLPQRKKDAS
                     LPYKPMEYRFSVDREVTEQLQRIAQQNQVTLNVLFQTIWGILVQKYNDQHSVVFGSVIN
                     GRPAAIPGVEQMIGLFINTLPVRVQTGENQSFQSLLHQMHEQMIQSHEFGFFPLSQIQK
                     ESAGGLSLFDHIIVFDHNPVEKRWERTLSGLGLQVTEQRVIEQTNYDFNVVVLPESEMQ
                     VQFQYNAHVYDRVSVEQTGKHLIHLMHQIAQNPDRLIEDLSLITEEEQKQILEVFNNTK
                     ADYPRDKTIHELFEEQTECVPDQTAIVYEGQQMTYRELNERANQLARTLQAKGVKADQP
                     VGIMVDRSLEMIVGLLGILKAGGAYVPIDPEYPKNRIEYMAADSGTKLLLTQSHLQDRV
                     TFAGTVVNLNEESSYHEERSNLEHIVQPNHLAYVIYTSGTTGKPKGVMVEHHSVINTLM
                     QLEKKYPLEKNDSILLKTNYTFDVSVTELFGWFFGEGKLIIAKSGLEKEPEALFNMIQE
                     KKITHINFVPSMLQVILNEITQTDIEKLQSLKYVFSAGEALSGKTIKQFYSYTLPAVLE
                     NLYGPTESTIYATQYTTNEEMKGLLNTPIGKPIRNVQAFIVKDIDQLQPIGVAGELCIS
                     GVGLARGYLNRPDLTAEKFVDNPFVPGEKMYRTGDLARWLPDGNIEYLGRIDHQVKIRG
                     YRIETGEIEAALLRIEAVQEAIVLAQENENRDKALCAYYVANQSFEVSEMKEKLSGQLP
                     SYMIPSYFVQLKQMPLTPNGKIDRKALPLPDGKLQTGAEYVEPRTPIEEVFVKVWKSVL
                     GAERVSILDNFYDLGGDSIKSIQVSSRLLQEGYKVEMKHLLKYPTIAQLSMYVEPANKA
                     AEQKEIIGTAPLTPIQSWFFEQKFVDHYFNQAMMLYQAERLDVTILRQVIRQIVQHHDA
                     LRTVFMIKEGQYEARIRGIEEGTLFTLDVFDLQGERDFARIIEAKANTIQSSMQISEGP
                     LVKLGLFQCPDGDHLLIVIHHLVVDMVSWRIIFEDFKTGYEQVKNGKKIQLPPKTDSFK
                     LWSERLSKYANSAEMEKERAYWNSTEQTVQGLLPKDKETQHTLNKNSEVVTVEWTEQET
                     EQLLKQTNQAYNTEINDLLLTALGMAIHKWTGMQEIVINLEGHGREAIMPELDITRTVG
                     WFTSQYPVVLQMKKGQDVSERIKTVKEGLRSIPGKGIGYGILRYCCKSQGEMLYTMKPE
                     ISFNYLGQLDQDLEGNALQMSPYSSGLTMSGDTVRLYVLNMNGMVQNGKLFFTIDYSKE
                     QYRSETIQQIGEWVKESLQEVIRHCTSKEKTEVTPSDLTLKGICMEELANVMEETKHIG
                     DIEDIYELTPMQKGMLFHTLADANSGAYFEQMTFDAVGKLHVEAFIRSLETLMQKHPVL
                     RTNIYQGWKDKPLQIVFKHKPCEWYYKDLRKMNPEEQDAYIRSCMGKDKARGFNLAEDA
                     LLRVTVLQTEEETHRIVWSFHHILMDGWCLPIIIKEWLEQYDVLLGKKQAKHVMVTPYS
                     RYMEWLAEQDEEEASKYWNEYLANYTEQTVIPYSKSKQKSEGYSAESVICGFGQALTHQ
                     LQQIANRNQVTMNTVIQTMWGILLQKYNNSEDVLFGSVVSGRPADITGIESMIGLFINT
                     IPVRVRSRKGMTCTQLMQSMQESALVSSKYDTYPLYEIQMQTEQKQDMIQHIMIFENYP
                     VEKELNSDDLSDDTKIRISNFRGEEQTNYDFNVVVMPGSEMEVQFQYNANVYDRVSVKR
                     IGKHLIHLMHQMIQNPDSLIENLRLITDEEQKQILDGFNNTKADYPRDKTIHELFEEQV
                     ECVPDQAAVVFEDKQMTYRELNERANQLARTLQAKGVKADQPVGIMAERSLEMIVGIFG
                     ILKAGGAYVPIDPEYPEERIQYLLKDANISVLLLQEHLKHKVTFNGQLIHLNDEEFYHS
                     DRSLLSPVAGSSNLAYVIYTSGTTGKPKGVMVEHRGIVNSLQWKKSFFGLSEEEHVLVL
                     LPYVFDAFVLNFFGPLISGATVYLLNNQDSKNPVMIKDIISREGITGFAATPRLLRLII
                     ENMEVNDFNHVKHVVVGGEQLETDIIKRLFSLNPDILLNNQYGPTENSVVSTYLPIRSP
                     GQPITIGKPVANHRVYILGEQNGLQPIGVTGELCVGGAGLARGYLNLPELTREKFVDDP
                     FVPGEKMYRTGDLARWLPDGNIEYLGRIDHQVKIRGYRIETGEIETALLNIEAVQEAIV
                     VAHENEKGDKALCAYYVVNKSFEASKMKEELSAQLPSYMIPSYFVQLEQMPLTPNGKID
                     RKALPDPNESFIRFTEYVAPNSGLEQIFVNVWREILDIDKIGVTDNLFDLGGNSISIIQ
                     FASRMSKDYNIHIPIQQILKTPSIRQLVRAISEKDTGITDYSSERIRLNPSNQSDKIIF
                     CFPPLGGLGIVYQHLSEILEDYDFYSFNFIESEDRMQKYIQLIKEIQPQSPYTLMGYSG
                     GGNLAFEVTKELEKQGDQVADLILVDSYIFSDANPEGLCVKERVNMAVNLMLEKFPQLQ
                     SGGESFLNDFRKKMQGYYLYFDEMDNSGLVSGNISVIKSPSKENKQVPGDIHMWRHSTT
                     GKFELYDGYGDHQKMLEHGFVVQNAKLIQKILRRQCP"
     aSDomain        3292..4188
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sevB_Condensation_DCL.1"
                     /domain_subtype="Condensation_DCL"
                     /evalue="1.90E-110"
                     /label="sevB_Condensation_DCL.1"
                     /locus_tag="sevB"
                     /protein_end="307"
                     /protein_start="8"
                     /score="360.5"
                     /tool="antismash"
                     /translation="QDIYPLSPMQEGMLFHSLEDTKSGAYFVQVVTSVYGELEPELLMK
                     SFKRLVQRHDVLRTTFLYDNLKEPLQIVLSERPLDMCMKRLDGSSNEIKNEWISQFLKQ
                     DREKGFDITMDSLIRLALLETGGGEWTIVLSFHHILMDGWCSDLIFNELFRIYDSLKQG
                     AAVEWSPAQPYSQYIKWLEKQDKEAAARYWKTYLNGYEPMARLPQRKKDASLPYKPMEY
                     RFSVDREVTEQLQRIAQQNQVTLNVLFQTIWGILVQKYNDQHSVVFGSVINGRPAAIPG
                     VEQMIGLFINTLPVRVQT"
     aSModule        3292..7800
                     /complete
                     /domains="nrpspksdomains_sevB_Condensation_DCL.1"
                     /domains="nrpspksdomains_sevB_AMP-binding.1"
                     /domains="nrpspksdomains_sevB_PCP.1"
                     /domains="nrpspksdomains_sevB_Epimerization.1"
                     /domains="nrpspksdomains_sevB_TIGR01720.1"
                     /locus_tags="sevB"
                     /monomer_pairings="X -> D-X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3301..3339
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0001"
                     /evalue="1.30E-05"
                     /label="C1_dual_004-017"
                     /locus_tag="sevB"
                     /protein_end="24"
                     /protein_start="11"
                     /score="17.7"
                     /tool="antismash"
                     /translation="YPLSPMQEGMLFH"
     CDS_motif       3364..3474
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0002"
                     /evalue="8.00E-12"
                     /label="C2_LCL_024-062"
                     /locus_tag="sevB"
                     /protein_end="69"
                     /protein_start="32"
                     /score="37.6"
                     /tool="antismash"
                     /translation="AYFVQVVTSVYGELEPELLMKSFKRLVQRHDVLRTTF"
     CDS_motif       3697..3762
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0003"
                     /evalue="3.40E-10"
                     /label="C3_DCL_135-156"
                     /locus_tag="sevB"
                     /protein_end="165"
                     /protein_start="143"
                     /score="32.3"
                     /tool="antismash"
                     /translation="FHHILMDGWCSDLIFNELFRIY"
     CDS_motif       3808..3846
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0004"
                     /evalue="3.80E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="sevB"
                     /protein_end="193"
                     /protein_start="180"
                     /score="10.0"
                     /tool="antismash"
                     /translation="PYSQYIKWLEKQD"
     CDS_motif       4087..4179
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0005"
                     /evalue="3.10E-18"
                     /label="C5_DCL_263-294"
                     /locus_tag="sevB"
                     /protein_end="304"
                     /protein_start="273"
                     /score="58.2"
                     /tool="antismash"
                     /translation="VVFGSVINGRPAAIPGVEQMIGLFINTLPVR"
     CDS_motif       4228..4332
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0006"
                     /evalue="1.20E-08"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="sevB"
                     /protein_end="355"
                     /protein_start="320"
                     /score="27.3"
                     /tool="antismash"
                     /translation="HEQMIQSHEFGFFPLSQIQKESAGGLSLFDHIIVF"
     aSDomain        4678..5877
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sevB_AMP-binding.1"
                     /evalue="4.60E-117"
                     /label="sevB_AMP-binding.1"
                     /locus_tag="sevB"
                     /protein_end="870"
                     /protein_start="470"
                     /score="382.9"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FEEQTECVPDQTAIVYEGQQMTYRELNERANQLARTLQAKGVKAD
                     QPVGIMVDRSLEMIVGLLGILKAGGAYVPIDPEYPKNRIEYMAADSGTKLLLTQSHLQD
                     RVTFAGTVVNLNEESSYHEERSNLEHIVQPNHLAYVIYTSGTTGKPKGVMVEHHSVINT
                     LMQLEKKYPLEKNDSILLKTNYTFDVSVTELFGWFFGEGKLIIAKSGLEKEPEALFNMI
                     QEKKITHINFVPSMLQVILNEITQTDIEKLQSLKYVFSAGEALSGKTIKQFYSYTLPAV
                     LENLYGPTESTIYATQYTTNEEMKGLLNTPIGKPIRNVQAFIVKDIDQLQPIGVAGELC
                     ISGVGLARGYLNRPDLTAEKFVDNPFVPGEKMYRTGDLARWLPDGNIEYLGRIDHQVKI
                     R"
     CDS_motif       4864..4905
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0007"
                     /evalue="1.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="sevB"
                     /protein_end="546"
                     /protein_start="532"
                     /score="18.4"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPID"
     CDS_motif       5089..5148
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0008"
                     /evalue="4.30E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="sevB"
                     /protein_end="627"
                     /protein_start="607"
                     /score="34.5"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGKPKGVMVEH"
     CDS_motif       5533..5556
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0009"
                     /evalue="2.60E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="sevB"
                     /protein_end="763"
                     /protein_start="755"
                     /score="4.8"
                     /tool="antismash"
                     /translation="YGPTESTI"
     CDS_motif       5671..5760
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0010"
                     /evalue="1.80E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="sevB"
                     /protein_end="831"
                     /protein_start="801"
                     /score="58.5"
                     /tool="antismash"
                     /translation="PIGVAGELCISGVGLARGYLNRPDLTAEKF"
     CDS_motif       5842..5907
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0011"
                     /evalue="1.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="sevB"
                     /protein_end="880"
                     /protein_start="858"
                     /score="36.6"
                     /tool="antismash"
                     /translation="YLGRIDHQVKIRGYRIETGEIE"
     CDS_motif       6115..6141
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0012"
                     /evalue="1.70E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="sevB"
                     /protein_end="958"
                     /protein_start="949"
                     /score="5.1"
                     /tool="antismash"
                     /translation="GKIDRKALP"
     aSDomain        6199..6396
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sevB_PCP.1"
                     /evalue="2.90E-20"
                     /label="sevB_PCP.1"
                     /locus_tag="sevB"
                     /protein_end="1043"
                     /protein_start="977"
                     /score="64.1"
                     /tool="antismash"
                     /translation="EEVFVKVWKSVLGAERVSILDNFYDLGGDSIKSIQVSSRLLQEGY
                     KVEMKHLLKYPTIAQLSMYVE"
     aSDomain        6433..7332
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sevB_Epimerization.1"
                     /evalue="9.90E-155"
                     /label="sevB_Epimerization.1"
                     /locus_tag="sevB"
                     /protein_end="1355"
                     /protein_start="1055"
                     /score="508.1"
                     /tool="antismash"
                     /translation="GTAPLTPIQSWFFEQKFVDHYFNQAMMLYQAERLDVTILRQVIRQ
                     IVQHHDALRTVFMIKEGQYEARIRGIEEGTLFTLDVFDLQGERDFARIIEAKANTIQSS
                     MQISEGPLVKLGLFQCPDGDHLLIVIHHLVVDMVSWRIIFEDFKTGYEQVKNGKKIQLP
                     PKTDSFKLWSERLSKYANSAEMEKERAYWNSTEQTVQGLLPKDKETQHTLNKNSEVVTV
                     EWTEQETEQLLKQTNQAYNTEINDLLLTALGMAIHKWTGMQEIVINLEGHGREAIMPEL
                     DITRTVGWFTSQYPVVLQM"
     CDS_motif       6445..6474
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0013"
                     /evalue="9.80E-04"
                     /label="NRPS-E1"
                     /locus_tag="sevB"
                     /protein_end="1069"
                     /protein_start="1059"
                     /score="12.2"
                     /tool="antismash"
                     /translation="LTPIQSWFFE"
     CDS_motif       6529..6603
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0014"
                     /evalue="1.00E-07"
                     /label="C2_LCL_024-062"
                     /locus_tag="sevB"
                     /protein_end="1112"
                     /protein_start="1087"
                     /score="24.3"
                     /tool="antismash"
                     /translation="RLDVTILRQVIRQIVQHHDALRTVF"
     CDS_motif       6808..6873
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0015"
                     /evalue="1.30E-10"
                     /label="NRPS-E2"
                     /locus_tag="sevB"
                     /protein_end="1202"
                     /protein_start="1180"
                     /score="33.4"
                     /tool="antismash"
                     /translation="LLIVIHHLVVDMVSWRIIFEDF"
     CDS_motif       7276..7326
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0016"
                     /evalue="3.10E-08"
                     /label="NRPS-E5"
                     /locus_tag="sevB"
                     /protein_end="1353"
                     /protein_start="1336"
                     /score="25.7"
                     /tool="antismash"
                     /translation="DITRTVGWFTSQYPVVL"
     aSDomain        7348..7800
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sevB_TIGR01720.1"
                     /evalue="6.20E-47"
                     /label="sevB_TIGR01720.1"
                     /locus_tag="sevB"
                     /protein_end="1511"
                     /protein_start="1360"
                     /score="151.1"
                     /tool="antismash"
                     /translation="VSERIKTVKEGLRSIPGKGIGYGILRYCCKSQGEMLYTMKPEISF
                     NYLGQLDQDLEGNALQMSPYSSGLTMSGDTVRLYVLNMNGMVQNGKLFFTIDYSKEQYR
                     SETIQQIGEWVKESLQEVIRHCTSKEKTEVTPSDLTLKGICMEELAN"
     CDS_motif       7369..7431
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0017"
                     /evalue="2.30E-10"
                     /label="NRPS-E6"
                     /locus_tag="sevB"
                     /protein_end="1388"
                     /protein_start="1367"
                     /score="32.6"
                     /tool="antismash"
                     /translation="VKEGLRSIPGKGIGYGILRYC"
     CDS_motif       7468..7497
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0018"
                     /evalue="1.10E-02"
                     /label="NRPS-E7"
                     /locus_tag="sevB"
                     /protein_end="1410"
                     /protein_start="1400"
                     /score="8.6"
                     /tool="antismash"
                     /translation="PEISFNYLGQ"
     aSDomain        7834..8733
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sevB_Condensation_DCL.2"
                     /domain_subtype="Condensation_DCL"
                     /evalue="5.40E-108"
                     /label="sevB_Condensation_DCL.2"
                     /locus_tag="sevB"
                     /protein_end="1822"
                     /protein_start="1522"
                     /score="352.4"
                     /tool="antismash"
                     /translation="EDIYELTPMQKGMLFHTLADANSGAYFEQMTFDAVGKLHVEAFIR
                     SLETLMQKHPVLRTNIYQGWKDKPLQIVFKHKPCEWYYKDLRKMNPEEQDAYIRSCMGK
                     DKARGFNLAEDALLRVTVLQTEEETHRIVWSFHHILMDGWCLPIIIKEWLEQYDVLLGK
                     KQAKHVMVTPYSRYMEWLAEQDEEEASKYWNEYLANYTEQTVIPYSKSKQKSEGYSAES
                     VICGFGQALTHQLQQIANRNQVTMNTVIQTMWGILLQKYNNSEDVLFGSVVSGRPADIT
                     GIESMIGLFINTIPVRVRS"
     aSModule        7834..11598
                     /complete
                     /domains="nrpspksdomains_sevB_Condensation_DCL.2"
                     /domains="nrpspksdomains_sevB_AMP-binding.2"
                     /domains="nrpspksdomains_sevB_PCP.2"
                     /domains="nrpspksdomains_sevB_Thioesterase.1"
                     /final_module
                     /locus_tags="sevB"
                     /monomer_pairings="tyr -> tyr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       7843..7884
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0019"
                     /evalue="9.50E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="sevB"
                     /protein_end="1539"
                     /protein_start="1525"
                     /score="14.4"
                     /tool="antismash"
                     /translation="YELTPMQKGMLFHT"
     CDS_motif       7903..8013
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0020"
                     /evalue="1.00E-09"
                     /label="C2_DCL_024-062"
                     /locus_tag="sevB"
                     /protein_end="1582"
                     /protein_start="1545"
                     /score="30.7"
                     /tool="antismash"
                     /translation="GAYFEQMTFDAVGKLHVEAFIRSLETLMQKHPVLRTN"
     CDS_motif       8239..8304
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0021"
                     /evalue="3.00E-10"
                     /label="C3_DCL_135-156"
                     /locus_tag="sevB"
                     /protein_end="1679"
                     /protein_start="1657"
                     /score="32.5"
                     /tool="antismash"
                     /translation="FHHILMDGWCLPIIIKEWLEQY"
     CDS_motif       8350..8388
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0022"
                     /evalue="4.80E-02"
                     /label="C4_DCL_171-183"
                     /locus_tag="sevB"
                     /protein_end="1707"
                     /protein_start="1694"
                     /score="7.0"
                     /tool="antismash"
                     /translation="PYSRYMEWLAEQD"
     CDS_motif       8629..8724
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0023"
                     /evalue="1.20E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="sevB"
                     /protein_end="1819"
                     /protein_start="1787"
                     /score="62.7"
                     /tool="antismash"
                     /translation="DVLFGSVVSGRPADITGIESMIGLFINTIPVR"
     CDS_motif       8773..8889
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0024"
                     /evalue="2.70E-11"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="sevB"
                     /protein_end="1874"
                     /protein_start="1835"
                     /score="35.8"
                     /tool="antismash"
                     /translation="QESALVSSKYDTYPLYEIQMQTEQKQDMIQHIMIFENYP"
     aSDomain        9229..10410
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sevB_AMP-binding.2"
                     /evalue="1.50E-119"
                     /label="sevB_AMP-binding.2"
                     /locus_tag="sevB"
                     /protein_end="2381"
                     /protein_start="1987"
                     /score="391.0"
                     /specificity="consensus: tyr"
                     /tool="antismash"
                     /translation="FEEQVECVPDQAAVVFEDKQMTYRELNERANQLARTLQAKGVKAD
                     QPVGIMAERSLEMIVGIFGILKAGGAYVPIDPEYPEERIQYLLKDANISVLLLQEHLKH
                     KVTFNGQLIHLNDEEFYHSDRSLLSPVAGSSNLAYVIYTSGTTGKPKGVMVEHRGIVNS
                     LQWKKSFFGLSEEEHVLVLLPYVFDAFVLNFFGPLISGATVYLLNNQDSKNPVMIKDII
                     SREGITGFAATPRLLRLIIENMEVNDFNHVKHVVVGGEQLETDIIKRLFSLNPDILLNN
                     QYGPTENSVVSTYLPIRSPGQPITIGKPVANHRVYILGEQNGLQPIGVTGELCVGGAGL
                     ARGYLNLPELTREKFVDDPFVPGEKMYRTGDLARWLPDGNIEYLGRIDHQVKIR"
     CDS_motif       9415..9456
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0025"
                     /evalue="2.70E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="sevB"
                     /protein_end="2063"
                     /protein_start="2049"
                     /score="17.4"
                     /tool="antismash"
                     /translation="FGILKAGGAYVPID"
     CDS_motif       9640..9699
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0026"
                     /evalue="4.30E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="sevB"
                     /protein_end="2144"
                     /protein_start="2124"
                     /score="34.5"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGKPKGVMVEH"
     CDS_motif       10072..10101
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0027"
                     /evalue="3.20E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="sevB"
                     /protein_end="2278"
                     /protein_start="2268"
                     /score="4.5"
                     /tool="antismash"
                     /translation="QYGPTENSVV"
     CDS_motif       10204..10293
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0028"
                     /evalue="6.40E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="sevB"
                     /protein_end="2342"
                     /protein_start="2312"
                     /score="53.6"
                     /tool="antismash"
                     /translation="PIGVTGELCVGGAGLARGYLNLPELTREKF"
     CDS_motif       10375..10440
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0029"
                     /evalue="1.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="sevB"
                     /protein_end="2391"
                     /protein_start="2369"
                     /score="36.6"
                     /tool="antismash"
                     /translation="YLGRIDHQVKIRGYRIETGEIE"
     CDS_motif       10648..10674
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0030"
                     /evalue="1.70E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="sevB"
                     /protein_end="2469"
                     /protein_start="2460"
                     /score="5.1"
                     /tool="antismash"
                     /translation="GKIDRKALP"
     aSDomain        10732..10938
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sevB_PCP.2"
                     /evalue="2.50E-16"
                     /label="sevB_PCP.2"
                     /locus_tag="sevB"
                     /protein_end="2557"
                     /protein_start="2488"
                     /score="51.5"
                     /tool="antismash"
                     /translation="EQIFVNVWREILDIDKIGVTDNLFDLGGNSISIIQFASRMSKDYN
                     IHIPIQQILKTPSIRQLVRAISEK"
     aSDomain        11008..11598
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sevB_Thioesterase.1"
                     /evalue="2.20E-30"
                     /label="sevB_Thioesterase.1"
                     /locus_tag="sevB"
                     /protein_end="2777"
                     /protein_start="2580"
                     /score="98.6"
                     /tool="antismash"
                     /translation="IFCFPPLGGLGIVYQHLSEILEDYDFYSFNFIESEDRMQKYIQLI
                     KEIQPQSPYTLMGYSGGGNLAFEVTKELEKQGDQVADLILVDSYIFSDANPEGLCVKER
                     VNMAVNLMLEKFPQLQSGGESFLNDFRKKMQGYYLYFDEMDNSGLVSGNISVIKSPSKE
                     NKQVPGDIHMWRHSTTGKFELYDGYGDHQKMLEH"
     CDS_motif       11152..11226
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sevB_0031"
                     /evalue="4.20E-09"
                     /label="NRPS-te1"
                     /locus_tag="sevB"
                     /protein_end="2653"
                     /protein_start="2628"
                     /score="28.8"
                     /tool="antismash"
                     /translation="QPQSPYTLMGYSGGGNLAFEVTKEL"
ORIGIN
        1 ttgaataaac aaaggaattc tataagtaga caaccgtatg aacaccaatt tgcctattgt
       61 ggtctgccaa tccatgaatt gttcgaacag caggtggacc ggaacccgga tcaaaccgcg
      121 gttgtcttca aaaacgaaca ggtaacctac cgccaattaa acgagagggc caatcagtta
      181 gccggagtac ttatggctag aaaggtaact accgatacag ttgtcgccat tatgcttgaa
      241 aaatctgtag aaatgatcgt aagtattctc gctgtgctta aggccggagg ttgttatctt
      301 cccattgata tagactatcc agggaataga attcagtaca tgttatctga tagtcaggca
      361 aagatcttga ttaccacgaa ggaaatatcg cagaatatcc gctttgaagg ggaacacgta
      421 ctgctgtatg acgattcgat ctggcatttt cctaaagaaa atccgaacgt caaaattcag
      481 gtaaccgatc tagcctacgt gatttataca tcagggacta ccggccaacc aaagggggtt
      541 atggtcgagc ataagggaat tgccaacctg aaagtggttt gggaagaaag ttttgggata
      601 tccccccggg acagaatagg tttttttgcc agcatttcat tcgacgcttc ggtttgggaa
      661 atattcatgg ctttactgaa tggagccaca ttatatgtgt tgtcaaagga actcctaagc
      721 aacctatgtg aatttcagaa ctatcttgga gaaaactcga ttacagttat gactctgccg
      781 ccttcctatg ctcaatacct ggatccggta tccctttttg atctaaggtt actcattaca
      841 gccggttccg caccatcaca gagtcttgtc aacaagtgga accaaattgt tacttatgta
      901 aatgcatatg gaccaacaga aacaagtata tgtgccacaa actggatagc gcctagggaa
      961 tggtgcaatg caagtcatat ccctattggg acgcctattc gtaatacaca ggtatatatt
     1021 ttggatgata acctgcaacc ggttgcaacc ggtgaatccg gacagctatg ggttggcggc
     1081 gtcggattag ccaggggata tctaaaccgg ccggaactga ccgctgaaaa gtttatcgat
     1141 aacccgttta ttcccggtga aaagttgtat tgcacggggg attacgcgag gtggctgtct
     1201 gacgggaata tagaatatcg cggcagaatg gaccatcaag tgaaaattag gggataccgc
     1261 atcgaactgg gcgagataga agcggttctc caaaaacatt ccggaatttc agaagctgct
     1321 gtactcgtga aaaaagataa actggggaac ccgtttttgt ccgcttatta tgttgcagaa
     1381 aaagaaatac ccggacattt actgcgctct tatatggaaa acgaattact tcattatatg
     1441 gttccctatc atttttattg tatagaaaac atgccgctaa cggtgaacgg aaaagtggac
     1501 cgtgaaaaac tgcttctgcc tgaatataat caagaaactt cttccaaata tacagccccc
     1561 cgtaatgagt tggaattgct tctggctgaa gtatggaaag atgtcttgga agtagaggag
     1621 gtaggaatcg atgataattt ctacctgctt ggcggagact ccattaaagc tattcagatg
     1681 gcttctaaat tgtacgagca ccaattaagg ctggatatga aagacttgat gatgaatccg
     1741 acaattagca cccttgcacc tgtagtagcc tttattgaac aagaatgcga ccaagggatt
     1801 gttcaaggcg aagtaccgtt gtctcctttt caacattggt tctttaagaa gcagttcacg
     1861 gccatgcatc attggaacca gtcggttctg ttatataacc cggaggggta taaccaagat
     1921 attctgcaga cggtactaat gaaattaatt gaacatcatg atgcattacg gatggtatat
     1981 acgcttgatg attcatttcc tacgcagata aaccggggaa tagaagggaa tttgttaggc
     2041 ttttctactt tcgatgtttc tgggcaaacg gatgcggggc aatttattca ccatgagata
     2101 aagagattac agagccgcat ggatttatcc caagggcctt tagttcaagc agggctgttc
     2161 cgtacggcgg aaggtgacca tttgtttttg gccattcatc acctggttat ggacggcgtt
     2221 tcatttcgca tattgctgga ggatctgtct aaaacatatg aacaggccat gcatggggaa
     2281 ttagtggttc tcccaagtaa aacagattct taccagactt ggacaaccag gttattggaa
     2341 tactccgctt ccggcgagtt tcttaaggag attccatact ggaaagaatt tgagcgcaaa
     2401 gtatcgtctg ttcccctgcc taaagacaaa acagcttcag aacataaaga gaaggacaag
     2461 cgttctatcc agctggaact aaccggggaa caaacgcagc aattgcttaa ggatgttcac
     2521 cgggcctatc atacggaaat caatgacatt cttctgaccg cattaggcct gactattcat
     2581 ggttggaccg ggcaaaaaca ggttttattg aatctggaat ctcatggccg ccacgatatt
     2641 ctcaaaggag ttaatatttc cagaacagtc ggatggttca cctcccaatg tcccgtaata
     2701 ttggacatgt cttatgcgga tgatgtatct catgaaataa aggtagtcaa agagaatatt
     2761 cggaaaattc cgaatcaggg aatcggatac gaaatgctac agtatttgac tcccgctgag
     2821 atgcgttccg gcctttcttt ttcaccggag ccggagattt gctttaatta tcttggccaa
     2881 ttggacaagg gaatgaattc ggaaagattc gcccaatccc catatagtaa cggagcatcg
     2941 ttagggcctg acggcgaagg gaatattggg gaggaaaatg agctgtattt tccgctcttt
     3001 ttgaccagtt atattcaaca cggccggttt caactcgtaa tttcatacag aggaaagcaa
     3061 tatcatcaga gcacaatggc tcatgtagct aacctgtata agcagcaatt gctaaatgta
     3121 atggatcatt gtctgaaaaa agaaaacgca gaacggacac ccaacgactt cacctgttca
     3181 aatctggaac tgaaagaact tgatcaggtc tatgcgctgc tggaacaatc tttaaaccaa
     3241 taaaaatcta aaaaggtggg agacatgatg acctttcaaa aagaacatgt tcaagatata
     3301 tacccccttt cccctatgca ggaagggatg ctgtttcatt cacttgaaga tacaaaatcg
     3361 ggcgcttact ttgttcaggt cgtaacttcc gtttacgggg aattggagcc cgaattgctg
     3421 atgaaaagtt ttaaaagact tgttcagcgc catgatgtgc tcagaaccac ttttttatat
     3481 gacaacttga aagaaccgct tcaaattgta ttaagtgaaa gacctcttga catgtgtatg
     3541 aaaagactgg atggttcaag caatgagata aagaatgaat ggatcagcca atttctgaaa
     3601 caggacaggg agaagggatt tgatataaca atggattccc ttatccggct ggccctgctg
     3661 gagaccggcg ggggcgaatg gaccattgtg cttagttttc atcacatcct gatggacggc
     3721 tggtgttcgg atctcatatt caacgagtta ttccgtattt atgactcatt aaagcagggt
     3781 gcggcagttg aatggtcccc tgctcagccg tacagccagt atatcaaatg gctggaaaag
     3841 caggataaag aagcagcggc ccgttactgg aagacatact tgaatggtta tgagcctatg
     3901 gcccgattgc cgcagagaaa gaaggatgcc tctttgccct ataaacctat ggagtaccga
     3961 ttttcagtgg acagagaggt aacggaacag ttgcaacgga ttgcccaaca aaatcaggtt
     4021 accttaaacg tactttttca aacgatttgg ggcatccttg tacagaaata taatgatcag
     4081 catagtgtcg tgtttggttc cgttataaat ggcagaccag ctgccatacc tggagtggaa
     4141 caaatgatcg gcttgtttat taacacactg cctgtccggg tacagaccgg agaaaaccaa
     4201 tcttttcaat ctctcctgca tcaaatgcac gaacagatga tacaatctca tgaatttggt
     4261 tttttccctt tgtcccagat tcaaaaagaa tctgccggag gcctatcctt atttgatcat
     4321 attatcgtat ttgatcataa tcctgttgag aagcggtggg aacgtaccct gtccggactt
     4381 ggcttgcagg ttacggaaca aagggtgatt gagcagacca actatgattt taatgtagta
     4441 gtattaccgg aaagcgaaat gcaggtccaa tttcaatata atgcacatgt atacgaccgg
     4501 gtgagtgtag aacaaacagg aaagcacctc attcatctta tgcatcaaat agcacaaaat
     4561 ccggataggc tgattgagga tctaagctta attaccgagg aagagcagaa gcaaattctg
     4621 gaggtattta acaacacgaa agccgattat ccaagagata agaccattca tgagttgttt
     4681 gaagaacaga cggagtgtgt accagatcaa acagcgatcg tctatgaagg acaacaaatg
     4741 acctatcgag agctgaatga gagggcgaac cagctggcga gaacacttca ggccaaaggt
     4801 gtgaaagctg atcagccggt tgggataatg gtagatcgtt ctcttgagat gatcgtgggc
     4861 ctactcggta tcctcaaagc aggcggagca tatgtgccca ttgatcctga atacccgaaa
     4921 aatcgtattg agtatatggc agcggattca ggaacaaagt tgttactgac ccaaagtcat
     4981 ttgcaggatc gtgtaacatt tgccggaact gtagtgaatc ttaatgagga aagcagttac
     5041 cacgaagaac gctcaaatct ggaacatatc gtacagccca atcatttggc ctacgtcatc
     5101 tatacctcgg gaactacggg gaagccaaaa ggggttatgg tcgaacatca ttcagtaatc
     5161 aataccttaa tgcaattaga aaaaaaatat ccgttagaga aaaatgattc cattttatta
     5221 aaaaccaact atacctttga tgtatcggta acagaattgt ttggatggtt ctttggagaa
     5281 ggcaagttaa ttatagctaa atcaggtcta gagaaggaac ccgaagcatt atttaacatg
     5341 atacaagaaa aaaaaattac tcatattaat tttgtaccgt ccatgcttca agtaatacta
     5401 aatgagataa cacaaacaga tatagaaaag cttcaatctt taaaatatgt attttcagct
     5461 ggagaagcgt tatcaggtaa gacgattaag caattttata gctatacact accagctgta
     5521 ttggaaaacc tgtatggacc tacagagtcc accatatatg caacccagta tacaacgaat
     5581 gaagaaatga aaggactcct aaatacgccg attggtaaac caataagaaa tgtacaagct
     5641 tttattgtaa aagatatcga tcaattacaa ccaataggag tggctggaga gttatgcatc
     5701 agtggagttg gtctggcccg gggatactta aatcgtcctg atttaaccgc agaaaaattt
     5761 gtggacaatc cgtttgttcc aggggagaag atgtatcgga caggggattt ggccagatgg
     5821 ctgccggacg gaaatataga atacttgggc cggatagacc atcaagtgaa gatacgcgga
     5881 taccgtattg aaaccgggga aattgaagcc gctttactcc gtatagaagc tgtacaggaa
     5941 gccattgttt tggcacaaga gaatgagaat agagataaag ccttatgtgc gtattacgta
     6001 gcaaatcagt cttttgaagt aagtgagatg aaagagaaat tatcagggca gttgccaagc
     6061 tatatgattc catcctattt tgtacaacta aagcagatgc cgttgacgcc aaacggaaaa
     6121 atagaccgga aggcattgcc gctgccagac gggaagctgc agaccggggc agagtatgtg
     6181 gaaccccgta caccgattga ggaagtattc gtaaaagtat ggaaatcggt attgggtgct
     6241 gagcgagtga gcattttaga taatttctat gatttgggcg gagattcgat taaatctatc
     6301 caagtctcat ccaggctgct gcaggaaggt tataaagtgg aaatgaaaca tttgctaaaa
     6361 tacccgacca ttgctcagct cagtatgtat gtggagcccg ccaacaaggc cgcagaacaa
     6421 aaagaaataa taggaacagc accgttaacg cccattcaat cgtggttctt tgaacaaaag
     6481 tttgtcgatc attatttcaa ccaggcgatg atgctatatc aagcagaacg tttggacgtt
     6541 accattttgc ggcaagtgat ccggcaaatt gttcagcatc atgacgcttt gcgtacggta
     6601 tttatgataa aagaaggcca atatgaagcg cggattcgcg gaatagagga aggaacgtta
     6661 ttcacactgg atgtgtttga tttgcaagga gaacgggact tcgcaaggat catcgaagct
     6721 aaggccaata caattcaaag cagtatgcaa attagcgaag gcccgttagt aaaactggga
     6781 ttgttccaat gtccggacgg cgaccactta ttaatcgtaa ttcatcactt ggttgtggat
     6841 atggtgtcat ggcggattat atttgaggac ttcaaaaccg gatatgagca agtgaaaaat
     6901 ggaaaaaaaa ttcagcttcc gccgaaaacg gattccttca aattgtggtc ggagcgactg
     6961 tccaaatatg cgaacagtgc tgaaatggaa aaagaaaggg cttattggaa ctcaaccgaa
     7021 caaaccgtac aagggctgtt gccaaaagat aaggaaacgc aacatacgct caataaaaac
     7081 agtgaagtcg tgacggttga atggacggag caagaaacag agcaattgct aaaacaaacc
     7141 aatcaagcgt ataacacgga aattaacgat ttgttattaa cagcgctggg tatggccatt
     7201 cataaatgga cagggatgca ggaaatcgta ataaatctgg aagggcacgg acgagaagcg
     7261 attatgcctg aactggatat tacccgaaca gtaggatggt ttacaagcca atatcccgta
     7321 gttcttcaga tgaagaaagg acaggatgtg tctgaacgga ttaaaacggt aaaagaagga
     7381 ctgcgcagta ttccgggaaa aggaataggt tacggcattt tacgctattg ctgcaaatcc
     7441 cagggcgaga tgttatacac gatgaagccg gagattagct ttaactattt gggacaattg
     7501 gatcaggatt tagaaggtaa tgccttacag atgtccccat attcaagcgg gctaacgatg
     7561 agtggagaca cagtcaggct gtatgtgtta aatatgaatg gaatggtgca aaacggaaaa
     7621 ctattcttca caattgacta cagtaaagag cagtatcgca gtgagacgat ccagcaaata
     7681 ggtgaatggg tcaaagaaag cctgcaagaa gttatccgtc attgcacaag caaagaaaaa
     7741 acagaagtaa cccccagtga cctaacgctg aaaggcatat gtatggaaga gctggcaaac
     7801 gtgatggaag agacgaagca tatcggagac atcgaggata tctatgaatt gacacccatg
     7861 caaaaaggga tgctattcca tactttggca gacgcaaact caggggcgta ctttgaacaa
     7921 atgacatttg atgcagtcgg aaaacttcat gttgaggcat ttataagaag tttggaaaca
     7981 ttgatgcaaa aacatccggt tttacggacg aatatttatc aaggatggaa agacaagccc
     8041 ttacaaattg tgttcaaaca taaaccgtgt gaatggtatt acaaagacct gcgcaagatg
     8101 aacccggaag agcaggatgc ctatatccgg tcctgtatgg gcaaggataa agcaagagga
     8161 tttaatttgg cggaagacgc cttgttacgg gtaactgtcc tgcaaacgga agaagaaaca
     8221 catcgaattg tctggagttt ccatcatatt ttaatggatg ggtggtgttt gcctatcatc
     8281 attaaagaat ggctggaaca atatgatgtg cttttaggga agaaacaagc taagcatgtg
     8341 atggttacgc cgtacagtcg atatatggag tggctcgccg aacaagacga ggaagaagca
     8401 tcgaagtact ggaatgagta tttggctaac tatacagagc agacggttat tccatattcc
     8461 aaatccaaac agaaatcaga aggatacagt gcagagagcg ttatttgtgg atttggacaa
     8521 gcgttaaccc atcaattaca gcaaattgca aaccggaatc aagtgacaat gaataccgtg
     8581 attcaaacga tgtggggtat attattacaa aaatacaaca atagtgaaga tgttctattt
     8641 ggcagcgtcg tatcgggcag gccggcggat ataactggta ttgagagtat gattgggctg
     8701 tttattaaca ccattcctgt acgggtgcga agtagaaaag ggatgacttg cacccaactg
     8761 atgcaaagca tgcaagagtc agcccttgta tccagcaaat acgatactta tccgctgtat
     8821 gaaatacaga tgcaaacgga acaaaaacaa gacatgattc agcacataat gatatttgag
     8881 aattatccag tagaaaagga gttaaacagc gatgacttat ctgatgatac aaagataaga
     8941 atttccaatt tccggggaga agagcagacc aattatgatt ttaatgttgt agtaatgccg
     9001 ggaagcgaaa tggaagttca atttcaatat aatgcgaatg tatacgatcg agtaagtgta
     9061 aagcgaatag ggaaacacct cattcatctt atgcatcaaa tgatacaaaa tccagatagt
     9121 ttgattgaga atttacgttt aattaccgat gaagaacaga agcaaattct ggacggtttt
     9181 aataatacga aagcagatta tccaagagac aagacgattc atgaattgtt tgaagagcag
     9241 gtagagtgtg ttcctgatca agcagccgta gtgtttgagg ataaacaaat gacttaccgg
     9301 gagctcaatg aacgggcgaa tcagctggcg agaacacttc aggccaaagg tgtgaaagct
     9361 gatcagccgg tgggtattat ggcagagcgt tcccttgaaa tgatcgtggg catattcggt
     9421 atccttaaag caggcggagc ttatgtaccc attgatcccg aatatccgga agaacgaatt
     9481 cagtatttgc tgaaggatgc taacattagc gtgttacttt tgcaggagca tttaaaacat
     9541 aaagtaacct ttaacgggca actgatccat ttaaatgatg aagaatttta ccatagtgac
     9601 cgctctttat tatcgccggt agcaggaagc agcaacctgg cctatgttat ttatacctcc
     9661 ggtacaacgg gcaaacctaa aggagtcatg gtagaacatc gcggaatagt gaactcgctt
     9721 cagtggaaaa agtcgttttt tgggctttct gaagaggaac atgtacttgt actgcttcca
     9781 tatgtgttcg atgcgtttgt tttaaatttc tttggtccgc ttatttcagg ggcaacggta
     9841 tatctcttga ataatcaaga cagcaaaaac cctgtcatga tcaaagacat tataagtagg
     9901 gaagggataa cgggctttgc agccactccc cgtctattga ggcttatcat agaaaatatg
     9961 gaggtaaatg actttaatca cgttaagcat gtcgttgttg gaggagaaca gcttgaaaca
    10021 gacattatca aaaggttgtt ttcattaaac ccagacatcc tgctaaataa tcaatatggc
    10081 ccaacggaaa atagtgttgt atctacttat cttcccattc gttcacccgg tcaacctatc
    10141 acgattggta agcctgtggc gaatcatcgt gtctatattt taggagaaca gaatggactt
    10201 cagccgattg gtgtaacagg ggaactgtgt gtcggaggtg cagggctcgc acggggatac
    10261 ttgaacctgc ccgaattgac aagagaaaaa ttcgtggatg atccgtttgt tccgggagag
    10321 aagatgtacc ggacagggga tttggccaga tggctgccgg atggaaatat agaatactta
    10381 ggacggatag accaccaagt gaagatacgg ggataccgca ttgaaaccgg ggaaattgaa
    10441 acagctttat taaatataga agctgtgcag gaagccattg ttgtggcaca tgagaatgag
    10501 aaaggagata aagccttatg tgcatactat gttgtgaata aatctttcga agcaagtaag
    10561 atgaaagaag agttatcggc tcaattgcca agctacatga ttccatctta ttttgtgcag
    10621 ttggagcaaa tgccgttgac gccgaatggg aagattgacc ggaaggcttt gcctgacccg
    10681 aatgaaagct ttattcgctt tacggagtat gtagctccca attctgggtt agaacaaata
    10741 tttgttaatg tatggcgaga aattttggat attgataaaa ttggtgtcac tgataacctg
    10801 ttcgaccttg gaggtaactc aataagcatc attcaatttg cttccagaat gtctaaggat
    10861 tataacatcc atattcctat ccagcaaatt ttaaaaactc caagtatccg gcaattagtg
    10921 cgggctattt cggagaagga taccggaata acggattact caagcgaaag gatcaggtta
    10981 aatccttcaa atcagtcgga taaaataatt ttctgtttcc cgccgttagg agggttaggt
    11041 atagtatacc agcatctttc agaaattttg gaggattatg atttttacag ttttaacttc
    11101 attgaatctg aggatagaat gcagaagtat attcaattaa tcaaagagat tcaacctcag
    11161 agcccttaca ccctgatggg ctactcaggg ggaggcaacc ttgcgtttga agtaacgaag
    11221 gaattggaga aacaaggtga tcaggtagca gatctgattt tggtggactc ctatatcttt
    11281 tcagacgcta acccggaagg gctctgtgta aaggaaaggg tcaatatggc agtaaacctt
    11341 atgctggaga aatttcctca acttcagagt gggggagaat ctttcctgaa cgattttaga
    11401 aaaaaaatgc aaggttacta tttgtatttt gatgagatgg acaattccgg cctagtttca
    11461 ggaaacatca gtgtgattaa atcgccttca aaggaaaaca agcaagtacc cggagatatt
    11521 catatgtgga gacactctac tacaggcaag tttgaattgt atgatggtta tggcgaccat
    11581 caaaagatgc tggagcatgg atttgtagta caaaatgcca agcttattca aaagatacta
    11641 agaaggcaat gtccctaa
//
