BGC0000427: shinorine biosynthetic gene cluster from Trichormus variabilis ATCC 29413
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 4,798,900 - 4,805,360 nt. (total: 6,461 nt).
This entry is originally from NCBI GenBank CP000117.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000427
Short description shinorine biosynthetic gene cluster from Trichormus variabilis ATCC 29413
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
CP000117.1
4798900 - 4805360
via Enzymatic assays, Heterologous expression
Compounds
  • shinorine
  • 4-deoxygadusol
  • mycosporine glycine
Species Trichormus variabilis ATCC 29413 [taxonomy]
References
Chemical products information
shinorine Evidence:
Copy SMILES
C13H20N2O8
4-deoxygadusol Evidence:
Copy SMILES
C8H12O5
mycosporine glycine Evidence:
Copy SMILES
C10H15N1O6
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • Ava_3855
  • ABA23460.1
 4798900 - 4801566 (-) Amino acid adenylation
    copy AA seq
    copy Nt seq
    • Ava_3856
    • ABA23461.1
    		 4801723 - 4803099 (-) ATP-grasp enzyme-like protein
      copy AA seq
      copy Nt seq
      • Ava_3857
      • ABA23462.1
      		 4803114 - 4803953 (-) O-methyltransferase, family 3
        copy AA seq
        copy Nt seq
        • Ava_3858
        • ABA23463.1
        		 4804128 - 4805360 (-) 3-dehydroquinate synthase
          copy AA seq
          copy Nt seq
          Biosynthesis information

          Biosynthetic modules

          Name
          0
          Type
          nrps-type1
          Genes
          Ava_3855
          Substrates
          serine (evidence: Activity assay)
          Integrated Monomers
          Domains
          adenylation
          Annotation changelog

          Entry version: 4

          Date
          Changes
          Submitters
          Reviewers
          2022-10-07
          Update chemical activity to schema version 2.11
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 3

          Date
          Changes
          Submitters
          Reviewers
          2022-09-15
          Corrected NRP module activity
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          2022-09-15
          Updated bioactivity data
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          2022-09-15
          Updated NRP substrate specificities
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 2

          Date
          Changes
          Submitters
          Reviewers
          2019-10-16
          Migrated from v1.4
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 1

          Date
          Changes
          Submitters
          Reviewers
          2015-06-12
          Submitted
          • (ID: AK6U5FV25F7Z3GQ43DVTSAVK)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          Detailed domain annotation
          Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
          A domain glossary is available here, and an explanation of the visualisation is available here.
          Selected features only
          Show module domains
          Similar known gene clusters from MIBiG 4.0
          Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
          Click on reference genes to show details of similarities to genes within the current region.
          Click on an accession to open that entry in the MiBIG database.