LOCUS       BGC0000428             32713 bp    DNA     linear   BCT 30-APR-2009
DEFINITION  Streptosporangium sibiricum strain DSM 44039 sibiromycin
            biosynthesis gene cluster, complete sequence.
ACCESSION   BGC0000428
VERSION     BGC0000428
KEYWORDS    .
SOURCE      Streptosporangium sibiricum
  ORGANISM  Streptosporangium sibiricum
            Bacteria; Actinobacteria; Streptosporangiales; Streptosporangiaceae;
            Streptosporangium.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 19:14:43
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            1..897
                     /gene="sibA"
     CDS             1..897
                     /codon_start=1
                     /gene="sibA"
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 117; E-value: 1.5e-35)"
                     /gene_kind="regulatory"
                     /note="putative regulator"
                     /product="SibA"
                     /protein_id="ACN39724.1"
                     /transl_table=11
                     /translation="MAEGLRDDVARHNYSVDIATTGRAVLEAFTSYDLILLDTDLPDLD
                     GVSVSRAIRQTSMIPIIAFASADEVDQVLLLETGCDDCIERPYRSRDVVARINAVLRRT
                     APITSPVPFASPVPFASPVPFASPAADLDSVVRARPRGVPPLAAVGEDLVLGEEQGQLI
                     RVGNRLVIDPALREARLGGELLTLTRKEYELLHLLASAPGRIFDRTELMIKIWDYPAGK
                     PVNAQASRTIDTHVSSLRRKLGHRDWIANLRGVGFRLDVPGPRRGGRQAPSRLVAADPE
                     EAPRHGWIRAEGAIESA"
     source          1..32713
                     /db_xref="taxon:457432"
                     /mol_type="genomic DNA"
                     /organism="Streptosporangium sibiricum"
                     /strain="DSM 44039"
     misc_feature    1..32713
                     /note="sibiromycin biosynthesis gene cluster"
     subregion       1..32713
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000428"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..32713
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     protocluster    1..27342
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2830:7342]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2831..7342
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..27342
                     /SMILES="NC([*])C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     gene            1061..1342
                     /gene="sibB"
     CDS             1061..1342
                     /codon_start=1
                     /gene="sibB"
                     /product="SibB"
                     /protein_id="ACN39725.1"
                     /transl_table=11
                     /translation="MTRTASPVTVMSTPSPRTFVPVSIVQSGLARMLCIFCSVGRAQNH
                     RAPSCQAPATGVTWGVAGGRTVVSQYNWAPSSRVRVASQSSGSAPGWL"
     gene            complement(1380..2810)
                     /gene="sibC"
     CDS             complement(1380..2810)
                     /codon_start=1
                     /gene="sibC"
                     /gene_functions="other (smcogs) SMCOG1087:hypothetical
                     protein (Score: 195.6; E-value: 2.5e-59)"
                     /gene_kind="other"
                     /note="putative kynurenine 3-monoxygenase"
                     /product="SibC"
                     /protein_id="ACN39726.1"
                     /transl_table=11
                     /translation="MSATPPKAVIVGAGPVGCLLAVELRRRDFDVEIYEKCDADTVLRP
                     GVGRSFNLTLTHRGLSVLHPWLRDRVYEIGSVLRQRIVHHTDGTLTRQPYGISDDQHLL
                     SVPRRELQRILLAEARASGARMFFGHSCVGADAHRGEAMFVDPRGTVRHAAGDILIGCD
                     GANSALRYELSKGGARMQVHQRYIAHGHVELTLTPEGSAALAPDGMHLWPRSDHFLQAQ
                     PNRDGSTTTTLFMPVGNEGGELRFRSLTGTEAVREHFEREYPDIAPHLPLAADEVIRAR
                     PALLKVVDCAPYNYGRAVLVGDSAHTIVPFFGQGINCSFEDADILCRLLDKYWRSGVDR
                     HEAIRAAGAEFSEQRVAAGQAISQLSMDNLHELSKSIDDAGFHRRQRLERMLHEYRPAE
                     FTQLYQLVAFTRTPYDEIIRRSRIDKLALDTLCELYDPDTEAETIISSYAEVRRGLDEH
                     DTREPALALTATPAKGEH"
     gene            complement(2831..7342)
                     /gene="sibD"
     CDS             complement(2831..7342)
                     /NRPS_PKS="Domain: Condensation_LCL (73-360). E-value:
                     1.9e-68. Score: 222.5. Matches aSDomain:
                     nrpspksdomains_sibD_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (525-926). E-value: 7.8e-91.
                     Score: 296.5. Matches aSDomain:
                     nrpspksdomains_sibD_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1037-1105). E-value: 2.6e-17.
                     Score: 54.6. Matches aSDomain: nrpspksdomains_sibD_PCP.1"
                     /NRPS_PKS="Domain: TD (1143-1380). E-value: 1.2e-72. Score:
                     235.9. Matches aSDomain: nrpspksdomains_sibD_TD.1"
                     /codon_start=1
                     /gene="sibD"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     325.2; E-value: 1.3e-98)"
                     /gene_kind="biosynthetic"
                     /note="putative nonribosomal peptide synthetase"
                     /product="SibD"
                     /protein_id="ACN39727.1"
                     /sec_met_domain="Condensation (E-value: 1.6e-56, bitscore:
                     182.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.5e-97, bitscore:
                     315.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-15, bitscore:
                     48.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.8e-60, bitscore:
                     194.9, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 9.5e-09, bitscore:
                     25.5, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDVLLTVVRDRWRTSSGRPEILAAELADILGRAVDPEDIAAAGS
                     PESLVARLTTGSVPAVGTPGTELRSAPAWPATPGQTGIWYLSEFGEARTAYNSPILLRV
                     PGALDPEALRAALEHVVRRHESLRTTFEMRDGTLTQLVAAEPRFGFRTAAVGSAGEAGR
                     LAAELAAEHLDLTDGPLLRAVCVDVGGDNTILLVSVHHAVFDGFSWSVLLSEWLTAYRR
                     AAAGERLPHDAPPVQFRQAVAALRPAGEAGLAYWTGHLAGVPVLDLPLDHPAGPRGRVA
                     AASVHTRLTASEVVRLRRQAASHGATPAVALLAAYALLMHRHTGQPDLTVGLPVSLRDR
                     SADQHVIGHLVNTVVLRHRVTPGSTGTDLLTATRDEVRAALAHKNVPFEQIVERLAPDR
                     ADGRPPLFQTMVTIMPAERRDLRHLGLGADAWQHLGSTPKFDLALVVEEAAEHLGLTFE
                     YDPAVLGHDTVTRMAARFRTVLAALMDDPDQRVHDLPWIPEDELRELRAAWSGPVDERP
                     ARQSLPQMFEARVREHPDRTAVRSSAGELTYRQLNSAANRLARALRRHGARRGTRVALR
                     LERGPDAVVGLLAVLKSGASFVPLDPAYPPQRLALMLRDANPEVLLVHGGSPVEVPAGT
                     TVVDFGSVELPADDTDPAGQRAADDEMYVVYTSGSTGRPKGVIINDITITNLVHRQDDL
                     SGLGETARTLQYMSISFDVSFMEIFCTLCAGGTVVVPDEQMRTDLRRLAGHLREQRVNR
                     IFLPYVALQELATVLTREDIHLPDLAEVYTTGEALVVTAQIRDMFRRCTPAVLINAYGP
                     SEAHLVSARRLPGDPSSWPERPAIGEVAGNVRAYVLDQQQRPVPFGVRGELYVGGPVVG
                     RGYLHLPDQTRERFRPDPYAGRPGGRMYRTGDLVMLTAPAGLVHLGRADEQIKIRGYRV
                     EPGEVEGALNDLPGITASAVVAAELEAGGRDLVAFVCTGSTLIDPRQVRDRLRASLPAY
                     MVPSRIVTLDRLPVAPSGKTDRAALAALASRSPDRPADVSDDRPLGETEQRVAALWAGL
                     LPGGGIGPDTDFYSAGGHSLLAVRLRQAVEDEFGMELPLSALLATPTVAGMAARVDAVR
                     AGHDEVDGPDLWADTRLLDGLRLGTTRAADARTSRTVLLTGVTGFLGSYLLRVLQQTGH
                     EVHCLVRADGEEQGRARIAEACRRYRVDANLADVRVVAGDLALERFGLHPADYEDLAGR
                     IGAVYHAAAHINFSAPYASVRSSNVDGFVRIAEFCADTVLKPLHHMSTLAVFSPAEPPR
                     TVDEDSIPSTAEGLGISYAQSKWVAERLALAARAHGVPVTVYRIGRIGPDSVTGACRTD
                     DFFWLQIKSFVRLGVVPADLGRPVDLLPVDMVADAVVRLGGSARARNRTVHIFHPTGID
                     WQTTLAALAAAGHHPRPVTTEEWLAALETAPAGADGNSLASLVPLFREGVMNLSEHRYV
                     NDRTVRDLAALGLEIPAAEPGWITSMIEYFTETGQLAPTSAP"
     aSDomain        complement(3203..3913)
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sibD_TD.1"
                     /evalue="1.20E-72"
                     /label="sibD_TD.1"
                     /locus_tag="sibD"
                     /protein_end="1380"
                     /protein_start="1143"
                     /score="235.9"
                     /tool="antismash"
                     /translation="VLLTGVTGFLGSYLLRVLQQTGHEVHCLVRADGEEQGRARIAEAC
                     RRYRVDANLADVRVVAGDLALERFGLHPADYEDLAGRIGAVYHAAAHINFSAPYASVRS
                     SNVDGFVRIAEFCADTVLKPLHHMSTLAVFSPAEPPRTVDEDSIPSTAEGLGISYAQSK
                     WVAERLALAARAHGVPVTVYRIGRIGPDSVTGACRTDDFFWLQIKSFVRLGVVPADLGR
                     PVDLLPVDMVADAVV"
     aSModule        3203..7123
                     /complete
                     /domains="nrpspksdomains_sibD_Condensation_LCL.1"
                     /domains="nrpspksdomains_sibD_AMP-binding.1"
                     /domains="nrpspksdomains_sibD_PCP.1"
                     /domains="nrpspksdomains_sibD_TD.1"
                     /final_module
                     /locus_tags="sibD"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(4028..4231)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sibD_PCP.1"
                     /evalue="2.60E-17"
                     /label="sibD_PCP.1"
                     /locus_tag="sibD"
                     /protein_end="1105"
                     /protein_start="1037"
                     /score="54.6"
                     /tool="antismash"
                     /translation="EQRVAALWAGLLPGGGIGPDTDFYSAGGHSLLAVRLRQAVEDEFG
                     MELPLSALLATPTVAGMAARVDA"
     CDS_motif       complement(4535..4600)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sibD_0009"
                     /evalue="4.50E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="sibD"
                     /protein_end="936"
                     /protein_start="914"
                     /score="34.7"
                     /tool="antismash"
                     /translation="HLGRADEQIKIRGYRVEPGEVE"
     aSDomain        complement(4565..5767)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sibD_AMP-binding.1"
                     /evalue="7.80E-91"
                     /label="sibD_AMP-binding.1"
                     /locus_tag="sibD"
                     /protein_end="926"
                     /protein_start="525"
                     /score="296.5"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FEARVREHPDRTAVRSSAGELTYRQLNSAANRLARALRRHGARRG
                     TRVALRLERGPDAVVGLLAVLKSGASFVPLDPAYPPQRLALMLRDANPEVLLVHGGSPV
                     EVPAGTTVVDFGSVELPADDTDPAGQRAADDEMYVVYTSGSTGRPKGVIINDITITNLV
                     HRQDDLSGLGETARTLQYMSISFDVSFMEIFCTLCAGGTVVVPDEQMRTDLRRLAGHLR
                     EQRVNRIFLPYVALQELATVLTREDIHLPDLAEVYTTGEALVVTAQIRDMFRRCTPAVL
                     INAYGPSEAHLVSARRLPGDPSSWPERPAIGEVAGNVRAYVLDQQQRPVPFGVRGELYV
                     GGPVVGRGYLHLPDQTRERFRPDPYAGRPGGRMYRTGDLVMLTAPAGLVHLGRADEQIK
                     IR"
     CDS_motif       complement(4688..4777)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sibD_0008"
                     /evalue="3.60E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="sibD"
                     /protein_end="885"
                     /protein_start="855"
                     /score="41.6"
                     /tool="antismash"
                     /translation="PFGVRGELYVGGPVVGRGYLHLPDQTRERF"
     CDS_motif       complement(5306..5359)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sibD_0007"
                     /evalue="3.00E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="sibD"
                     /protein_end="679"
                     /protein_start="661"
                     /score="25.9"
                     /tool="antismash"
                     /translation="MYVVYTSGSTGRPKGVII"
     CDS_motif       complement(5540..5581)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sibD_0006"
                     /evalue="3.10E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="sibD"
                     /protein_end="601"
                     /protein_start="587"
                     /score="14.1"
                     /tool="antismash"
                     /translation="LAVLKSGASFVPLD"
     CDS_motif       complement(6110..6223)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sibD_0005"
                     /evalue="1.20E-16"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="sibD"
                     /protein_end="411"
                     /protein_start="373"
                     /score="53.1"
                     /tool="antismash"
                     /translation="RDEVRAALAHKNVPFEQIVERLAPDRADGRPPLFQTMV"
     aSDomain        complement(6263..7123)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sibD_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.90E-68"
                     /label="sibD_Condensation_LCL.1"
                     /locus_tag="sibD"
                     /protein_end="360"
                     /protein_start="73"
                     /score="222.5"
                     /tool="antismash"
                     /translation="WPATPGQTGIWYLSEFGEARTAYNSPILLRVPGALDPEALRAALE
                     HVVRRHESLRTTFEMRDGTLTQLVAAEPRFGFRTAAVGSAGEAGRLAAELAAEHLDLTD
                     GPLLRAVCVDVGGDNTILLVSVHHAVFDGFSWSVLLSEWLTAYRRAAAGERLPHDAPPV
                     QFRQAVAALRPAGEAGLAYWTGHLAGVPVLDLPLDHPAGPRGRVAAASVHTRLTASEVV
                     RLRRQAASHGATPAVALLAAYALLMHRHTGQPDLTVGLPVSLRDRSADQHVIGHLVNTV
                     VLRHRV"
     CDS_motif       complement(6272..6361)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sibD_0004"
                     /evalue="4.10E-10"
                     /label="C5_LCL_267-296"
                     /locus_tag="sibD"
                     /protein_end="357"
                     /protein_start="327"
                     /score="32.1"
                     /tool="antismash"
                     /translation="DLTVGLPVSLRDRSADQHVIGHLVNTVVLR"
     CDS_motif       complement(6389..6430)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sibD_0003"
                     /evalue="1.30E-02"
                     /label="Cy4"
                     /locus_tag="sibD"
                     /protein_end="318"
                     /protein_start="304"
                     /score="8.7"
                     /tool="antismash"
                     /translation="GATPAVALLAAYAL"
     CDS_motif       complement(6683..6748)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sibD_0002"
                     /evalue="1.70E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="sibD"
                     /protein_end="220"
                     /protein_start="198"
                     /score="20.7"
                     /tool="antismash"
                     /translation="VHHAVFDGFSWSVLLSEWLTAY"
     CDS_motif       complement(6950..7063)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sibD_0001"
                     /evalue="2.90E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="sibD"
                     /protein_end="131"
                     /protein_start="93"
                     /score="58.3"
                     /tool="antismash"
                     /translation="TAYNSPILLRVPGALDPEALRAALEHVVRRHESLRTTF"
     gene            complement(7339..9129)
                     /gene="sibE"
     CDS             complement(7339..9129)
                     /NRPS_PKS="Domain: AMP-binding (15-405). E-value: 6.7e-90.
                     Score: 293.4. Matches aSDomain:
                     nrpspksdomains_sibE_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (521-584). E-value: 6.7e-13.
                     Score: 40.9. Matches aSDomain:
                     nrpspksdomains_sibE_PP-binding.1"
                     /codon_start=1
                     /gene="sibE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     322.8; E-value: 5.4e-98)"
                     /gene_kind="biosynthetic"
                     /note="putative nonribosomal peptide synthetase"
                     /product="SibE"
                     /protein_id="ACN39728.1"
                     /sec_met_domain="AMP-binding (E-value: 7.4e-96, bitscore:
                     311.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.2e-13, bitscore:
                     40.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSALPSLRVPTLPVAFEAAARAAGDRIALEYGSSSITYRELDAAA
                     NRFARRLLREGVTPGSRVGLHMTRCLELYIAMIGLLKAGAVVVPLNPSHPVTVRRSVVR
                     EADLPLTLRDVPAGLSSVTVERDVHELLAAGADLDDTSPGLCTDPESTAFILFTSGSTG
                     RPRGVRIAHRGIARVASYNGEVEVRPDDCFLQLAPYSFAASTTDIWLSLLHGARVVVLP
                     SQLPSLPKLAHTIKEYGVTFLNLPGGLMNLLIDAHPEAFAKVRTVIVSGDFPSAPHLAR
                     VMKAVPGTVYNAFGCTENSALTAVHPMTPEDLQLGVVPIGLPLPGVGLHVLGEDMTPCA
                     PGEVGEMHISGAGLAQGYLGLPEETAAKFPTVDGVRMLRTGDWARTTPAGEVVLVGRTD
                     QMVKIRGFRVELREVELAADQSGLVEKAVVRAVDATDGQKELVLFCTTATGEAPSIEAL
                     LADLKSRLPDYMLPARVHHLAELPVNVNGKLDRMALREPRAVLVEPDGTAQQQPVVRDI
                     IATTVTRLLAVVTGREPIGVSDSFLASGANSLQVIQLAASLHDVMGVDVRPEDIFQLDN
                     AESLAGHIRALRQGHREVPA"
     aSDomain        complement(7378..7566)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sibE_PP-binding.1"
                     /evalue="6.70E-13"
                     /label="sibE_PP-binding.1"
                     /locus_tag="sibE"
                     /protein_end="584"
                     /protein_start="521"
                     /score="40.9"
                     /tool="antismash"
                     /translation="VTRLLAVVTGREPIGVSDSFLASGANSLQVIQLAASLHDVMGVDV
                     RPEDIFQLDNAESLAGHI"
     aSModule        7378..9084
                     /complete
                     /domains="nrpspksdomains_sibE_AMP-binding.1"
                     /domains="nrpspksdomains_sibE_PP-binding.1"
                     /locus_tags="sibE"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(7885..7947)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sibE_0003"
                     /evalue="2.70E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="sibE"
                     /protein_end="415"
                     /protein_start="394"
                     /score="29.2"
                     /tool="antismash"
                     /translation="VGRTDQMVKIRGFRVELREVE"
     aSDomain        complement(7915..9084)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sibE_AMP-binding.1"
                     /evalue="6.70E-90"
                     /label="sibE_AMP-binding.1"
                     /locus_tag="sibE"
                     /protein_end="405"
                     /protein_start="15"
                     /score="293.4"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FEAAARAAGDRIALEYGSSSITYRELDAAANRFARRLLREGVTPG
                     SRVGLHMTRCLELYIAMIGLLKAGAVVVPLNPSHPVTVRRSVVREADLPLTLRDVPAGL
                     SSVTVERDVHELLAAGADLDDTSPGLCTDPESTAFILFTSGSTGRPRGVRIAHRGIARV
                     ASYNGEVEVRPDDCFLQLAPYSFAASTTDIWLSLLHGARVVVLPSQLPSLPKLAHTIKE
                     YGVTFLNLPGGLMNLLIDAHPEAFAKVRTVIVSGDFPSAPHLARVMKAVPGTVYNAFGC
                     TENSALTAVHPMTPEDLQLGVVPIGLPLPGVGLHVLGEDMTPCAPGEVGEMHISGAGLA
                     QGYLGLPEETAAKFPTVDGVRMLRTGDWARTTPAGEVVLVGRTDQMVKIR"
     CDS_motif       complement(8023..8109)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sibE_0002"
                     /evalue="2.70E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="sibE"
                     /protein_end="369"
                     /protein_start="340"
                     /score="42.1"
                     /tool="antismash"
                     /translation="PGEVGEMHISGAGLAQGYLGLPEETAAKF"
     CDS_motif       complement(8614..8673)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sibE_0001"
                     /evalue="1.00E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="sibE"
                     /protein_end="172"
                     /protein_start="152"
                     /score="24.3"
                     /tool="antismash"
                     /translation="AFILFTSGSTGRPRGVRIAH"
     gene            complement(9206..11518)
                     /gene="sibF"
     CDS             complement(9206..11518)
                     /codon_start=1
                     /gene="sibF"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 66.6; E-value:
                     4.9e-20)"
                     /gene_kind="transport"
                     /note="putative UvrA-drug resistance pump"
                     /product="SibF"
                     /protein_id="ACN39729.1"
                     /transl_table=11
                     /translation="MAADRQHIVVTGARTNNLKGIDLRIPLGKLTVVTGVSGSGKSSLV
                     FGTIAVESQRQLNEVFPAFIRNRLPRYERPEFELIENLSPAIVVDQKAVGGGNRSTVGT
                     MTEVSPILRVMFSRYGEPSAGPSNFYSFNDPQGMCPECEGLGATLQLDVERLLDKNLSL
                     NEGAIQHPNFAVGTNYWKRYAQVARFEAGKARGADLEPLFDANKPLARYTKSEMDLLLY
                     GEGFQTTRPDEFNNVAVNDYEGLVLRFTRRFVKPGLDSLKDKERKATEKVVTEQVCPAC
                     EGARLSPAAVASRIDGHNIADFCAMEIGDLVTELVRLEKRWPGPVVPAALASLRRIESV
                     GLGYLTLNRPTRTLSGGEGQRLKTVRHLGSSLTGMTYIFDEPSVGLHAHDVDRLNQLLT
                     ALRDKGNTVLIVEHNRDVIEIADHVIDVGPGPGASGGEIIFTGTVKQLAASDTLTGRSF
                     KALPGLKPETRTPTGSLPIRKATLHNLRGVDVDFPTGVLTVVTGVAGSGKSTLASKVFA
                     AEYPYAIVLDQSAVGINPRSTPATYTGVWDLVRKQFAVAHHVDISLFSFNAKGACPECK
                     GRGTITTDLAFMDPVTVVCEVCGGTRYRQDVLEHRIDGLNIAEVLDLTVEESREWFDDR
                     AIVKRLEPLREVGLGYLTLGRPLSMLSGGERQRLKLADRLHESGSVYLFDEPTTGLHMA
                     DVQNLLALLDRLVDAGNTVIAIEHDLDVVKHSDWVIDIGPGAGEHGGQVVFTGTPADMA
                     EKGRTRTADYLRAALPR"
     gene            complement(11565..12620)
                     /gene="sibG"
     CDS             complement(11565..12620)
                     /codon_start=1
                     /gene="sibG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     125.2; E-value: 4.6e-38)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative NADH-flavin oxidoreductase"
                     /product="SibG"
                     /protein_id="ACN39730.1"
                     /transl_table=11
                     /translation="MRILVNGGGPAGMAFAMFAARSGRGDEITVRDWTGPGDTYGFGVI
                     LPPAAVEVFRDAEPDLADELNSHITAWDRLSVHRHGRTASIPAPRLGAMDRRTLLKVLR
                     RRCAERGVRFEHGAVDPALGDHDLVVAADGARSVTRRHRAAAFGTTTREIGPAYIWLGA
                     DRALEHLRFLVAETPDGPAVAHAYPYSPDRSTFLVEADGAPPPAVLAEWFAGPLGGARL
                     LENRSRWSRFQEIHNRTWSAGNVVLIGDAAHTAHYSIGSGTRLALDDARALADALCAQP
                     RLADALKGYEDARRPIVEHTQRIGRLSATWFTRLPDVPMERLLDDLATRGGQISWRDLA
                     TEGSGAVPVRG"
     gene            complement(12617..13795)
                     /gene="sibH"
     CDS             complement(12617..13795)
                     /codon_start=1
                     /gene="sibH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 256;
                     E-value: 1.2e-77)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative glycosyltransferase"
                     /product="SibH"
                     /protein_id="ACN39731.1"
                     /sec_met_domain="MGT (E-value: 3.1e-100, bitscore: 326.8,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRYLFTAMPVASHFMPLVPLAHAALSGGHDVLVATSGPATRTAVA
                     AGLVTADAGGSRQARQPYDDLLDMLARGEAGVAPDDPTSLAVHGRQFGEVGARQLDDIV
                     TIARDWRADAVVYLGIHAAALVAARAAGIPAVLHGYGTPLPTFEPSLEHLAPHAARFGV
                     DTVTEAEFEIDVLPPSLANFTDVPTTIGKPQHTLAMRYGCFNNGGTLPHWALRRGDVPR
                     VVATCGSAPAMTLDGRLYRDIVTATERLGAELILLTADADLPELPSELPPHVRSERWLP
                     LRALLNTTDAVVHHGGSGTFLSTLAAGLPQVTLPMPGTVNMTNARSLTARGTGPTVNLS
                     EVSPDTLTAALEAVLRDPGPRRAAEEVAAEMATMPTTASVINRISQLIQDSR"
     gene            complement(13798..14793)
                     /gene="sibI"
     CDS             complement(13798..14793)
                     /codon_start=1
                     /gene="sibI"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 281.9; E-value:
                     9.1e-86)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative dTDP-glucose synthase"
                     /product="SibI"
                     /protein_id="ACN39732.1"
                     /transl_table=11
                     /translation="MKGIIMAGGSGSRLKPLTGVLSKQLLPVYNKPMIYYPLSVLMLAG
                     VTEVLIISSPQHLPLFRAMLGDGDRLGMRLTYAEQHRPAGIAEAFLIGAGHIGDDSVSL
                     VLGDNIFHGPGFSALLREQARRVDGCTLFGYPVRDPHRYGVAVVDSGGHLTDIEEKPDR
                     PRSELAVTGLYMYDNDVVGIARGLRPSARGELEVTDINRAYLERGKARLVQLGRGFVWL
                     DTGTHEALLEAGQYVHILEQRQSVRIACLEEIAFRMGFIDRAALQRLGREHADTDYGAY
                     LTEIADKPPATWSVSDGTSAPAAMTDPIGLPEHTGDTKPLVPTPAGLFRS"
     gene            complement(14790..15371)
                     /gene="sibJ"
     CDS             complement(14790..15371)
                     /codon_start=1
                     /gene="sibJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /note="putative dTDP-4-keto-6-deoxyglucose 3,5-epimerase"
                     /product="SibJ"
                     /protein_id="ACN39733.1"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 1.1e-43,
                     bitscore: 139.6, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTRELAVDGALELTLPVFPDERGMFCPIYQDGALSVPFPIRRSA
                     LSVNRAGAARGIHYAPGGDGPTKIVHCVSGSAIDFVVDVRVGSPTFGHWDTILLDADLP
                     RAVYLPAGLGHGFVALTGGTVVSYLMTTAYQAGDEQPVSLLDPALGLPLPAAQELVMSP
                     ADRAAPTLAEALGRGLLPPYRTGPAEEDET"
     gene            complement(15368..16189)
                     /gene="sibK"
     CDS             complement(15368..16189)
                     /codon_start=1
                     /gene="sibK"
                     /note="putative esterase/aryl formamidase"
                     /product="SibK"
                     /protein_id="ACN39734.1"
                     /transl_table=11
                     /translation="MTSVRTELDRQLSPSTVARDAPVTLARYRLRSQAARRDLVHHADL
                     RYGSHPAEVLHHFPPRRPGSPLLIFIHGGHWQESSKEDACFPAPGLIAAGFGYLALGYG
                     LAPQRSLPEMTASVRRGLTWVLDHAEELGGRPDAVFAAGSSAGAHLAAMAADLPLAGLF
                     LLSGLYDLSPVIGSYVNNALGLTAEEAARLSPMLRPPPAVPVLLAVGEHETREYHGQQR
                     RYAAALRLAATPVTELVVAGRDHFDLPFDLGDPATVLGAAVVRAAQPKGAP"
     gene            complement(16186..17220)
                     /gene="sibL"
     CDS             complement(16186..17220)
                     /codon_start=1
                     /gene="sibL"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 242.8; E-value:
                     9.6e-74)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative C-methyltransferase"
                     /product="SibL"
                     /protein_id="ACN39735.1"
                     /transl_table=11
                     /translation="MSSELSALVPVLFGHAAFQQLNAGCQLGLFELLHERGPLSAEEVA
                     DALRLPRRSADILLLGTTALGLSTVTDGGYRNGAPIGAAFRDGLWPVLRDIVQYQDKIA
                     YQPAADYVESLRTGQNAGIRHFPGTTRDLYSRLAAVPGLEELFYRGMHAWSQLSNPVLL
                     AQPDFTRVHRVLDVGGGDAVNAVALARAHPSLRVTVLDRPGALEVARKTIAEAGLEERV
                     RTHAADIFTDSYPAGHDCVLFAHQLVIWSPEQNLTLLRKAYDAVEPGGRVLVFNAFTDD
                     DRTGPLYAALDNVYFTTLPFRHSTIHRWADCESWLREAGFTDVGRTAPPGWTPHGVVSG
                     SRPR"
     gene            complement(17217..18467)
                     /gene="sibM"
     CDS             complement(17217..18467)
                     /codon_start=1
                     /gene="sibM"
                     /note="putative sugar C-methyltransferase"
                     /product="SibM"
                     /protein_id="ACN39736.1"
                     /transl_table=11
                     /translation="MTTEIAKSVTTCRVCGAADWQEVISFGSVPLANAYLDKPGPEEAY
                     PLELISCRSCRLLSLTAVVDPQALYRDYAYVTSESETMTHHMRDVVRLCRERIDAGGLV
                     VELGSNTGNQLQLFQQAGHPVLGVDPAQNLAAIAERRGVPTVADYFNEKVATAIAGEHG
                     RASLILGRHVFAHIDDLADVLRGVKALLTDDGLFAIEVPYACDLLERVAFDTIYHEHLS
                     YFLISTLDRLFTRHGLRAIDVRRLAVHGGSVLVTAARMGSRWETDERVGELIAYEKSER
                     LDTDARYEQFAARVHALRRELTELVRKEAANGKRVAGYGASAKGTTLLNICELTSTEVR
                     FCTDTTPQKQGRFVPGTQIPIVAPGDVSEQPDLYLLLAWNYAEEILQREAAFLDAGGAF
                     IIPVPEPAVYARQKVRQ"
     gene            complement(18464..19633)
                     /gene="sibN"
     CDS             complement(18464..19633)
                     /NRPS_PKS="Domain: Aminotran_1_2 (17-166). E-value:
                     1.1e-15. Score: 49.5. Matches aSDomain:
                     nrpspksdomains_sibN_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="sibN"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     328.3; E-value: 1.1e-99)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative dTDP-4-keto-6-deoxyglucose transaminase"
                     /product="SibN"
                     /protein_id="ACN39737.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.1e-97,
                     bitscore: 318.2, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVAPTVPFHVPHTARHQAEYMSSALVSGDLDGNGDYSARASALI
                     QRITGAGQVLLTPSCTAALEIAALLLDLAPGDEVVMPSFTFAPTASAFALRGAVPVFVD
                     CHPETLNLDEKALEEAITERTRAIIAVHYAGVACEMDEIMRIAERHGIPVLEDNAHGLG
                     ASYRDRPLGSIGRLAAQSFHATKNVHSAKGGALLVNDDGMVDRATIIRDRGTNRHQYFL
                     GQVDKYRWVDLGSSYILPELLAALLAAQLEEHDAVQRQRRAVWYRYHEGLAEWAGDQRV
                     QLPAVPADRVHSAHLYHLVLPEPADRAAFLNHLRARGVTATIHFVPLHNSPAGQRYGRT
                     VPGGCPITEHVADRLVRLPLHTGLTPAQVEQVVDAVVSFRTSESRGSQP"
     aSDomain        complement(19136..19582)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sibN_Aminotran_1_2.1"
                     /evalue="1.10E-15"
                     /label="sibN_Aminotran_1_2.1"
                     /locus_tag="sibN"
                     /protein_end="166"
                     /protein_start="17"
                     /score="49.5"
                     /tool="antismash"
                     /translation="QAEYMSSALVSGDLDGNGDYSARASALIQRITGAGQVLLTPSCTA
                     ALEIAALLLDLAPGDEVVMPSFTFAPTASAFALRGAVPVFVDCHPETLNLDEKALEEAI
                     TERTRAIIAVHYAGVACEMDEIMRIAERHGIPVLEDNAHGLGASY"
     gene            complement(19630..20367)
                     /gene="sibO"
     CDS             complement(19630..20367)
                     /codon_start=1
                     /gene="sibO"
                     /note="putative N-methyltransferase"
                     /product="SibO"
                     /protein_id="ACN39738.1"
                     /transl_table=11
                     /translation="MNRLGLTMGEEAYEHALRSDDTREFELLDRTWTQLSGVVGGEYNY
                     ATGLFASSLPYDGVHSMLEMGCGCGVAAVLGALAGVPRVTALDINPAAVRTAQLNAERH
                     GVADRVTALVSDLFSAVPEDTAYDLIFWNSPFIQVPADHALDSDLAYHFFDPGYTMHER
                     FLREARRRLTPAGRLFLGFSFAMGSGDRLHDAAAAAGLDVRIHVQESFAAAPEELGTSP
                     VYREHAGDDARVHIDFTLLELVR"
     gene            complement(20400..21185)
                     /gene="sibP"
     CDS             complement(20400..21185)
                     /codon_start=1
                     /gene="sibP"
                     /note="putative tryptophan 2,3-dioxygenase"
                     /product="SibP"
                     /protein_id="ACN39739.1"
                     /transl_table=11
                     /translation="MNDANPYVDYARMDALHALQLPVTDSPFEMQFILLSQVKELLFRM
                     VHLELEQARTRICEDRPEAACRALSRAVRHQRTLIGCWESMNAMPVDEFLPFRDTLGEA
                     SGTQSYMYRLLEFTLGNRVSAMVRPTDFTRFPQLSAELQRPSLYDEVLRHLARTGLPVP
                     EHILTRDVTGPYVPDDAVEDVWATVYRSPDKYRAAYDLAEQLLEVAYQFSRWRATHLLV
                     VERMIGGKRGLGGTDGAAWLRKINEHRFFAELWTARSAL"
     gene            complement(21182..22363)
                     /gene="sibQ"
     CDS             complement(21182..22363)
                     /NRPS_PKS="Domain: Aminotran_5 (110-359). E-value: 2.2e-20.
                     Score: 64.7. Matches aSDomain:
                     nrpspksdomains_sibQ_Aminotran_5.1"
                     /codon_start=1
                     /gene="sibQ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 112.9; E-value:
                     2.7e-34)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative kynurenine hydrolase"
                     /product="SibQ"
                     /protein_id="ACN39740.1"
                     /transl_table=11
                     /translation="MESTRGWAEKEASADPLAVFAKDFLIPEGTLALNGNSLGPPAAAV
                     PIALSNAVRQWSEHLIRGWWDDGWWDAPERVGDRIGRLMGAGPGQVVVGESASVQLFNA
                     LTAAVRLVPERRVLIADAGNFPTDRYLAASVARLLGLRLVETSMNDLPGALARHAGQVG
                     AVLCGAVDFRTGELWDVPGLTTAIHQAGGVSVWDLSHAAGAVPVQADAAGVDLAVGCGY
                     KYLSGGPGAPAFLYAARRHHHALDFAVTGWHGHADPFAMSASFVPADGITRARTGTPQI
                     LSLLALEAALEPLEAAGMAAVRAKSLRLADYLFALVADLDSVEIVTPRDPHRRGNHVTL
                     RLPDAVAVAESLARRGVIVDERPPDLLRICLNGLYISWTDVYDAVTHLREVLR"
     aSDomain        complement(21287..22033)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sibQ_Aminotran_5.1"
                     /evalue="2.20E-20"
                     /label="sibQ_Aminotran_5.1"
                     /locus_tag="sibQ"
                     /protein_end="359"
                     /protein_start="110"
                     /score="64.7"
                     /tool="antismash"
                     /translation="LVPERRVLIADAGNFPTDRYLAASVARLLGLRLVETSMNDLPGAL
                     ARHAGQVGAVLCGAVDFRTGELWDVPGLTTAIHQAGGVSVWDLSHAAGAVPVQADAAGV
                     DLAVGCGYKYLSGGPGAPAFLYAARRHHHALDFAVTGWHGHADPFAMSASFVPADGITR
                     ARTGTPQILSLLALEAALEPLEAAGMAAVRAKSLRLADYLFALVADLDSVEIVTPRDPH
                     RRGNHVTLRLPDAVAVAESLARRGVIV"
     gene            22570..23322
                     /gene="sibR"
     CDS             22570..23322
                     /codon_start=1
                     /gene="sibR"
                     /product="SibR"
                     /protein_id="ACN39741.1"
                     /transl_table=11
                     /translation="MVARCAAPRCPVTVTAGSPLCPACVARLGRDLRRLPSLYQQCGER
                     HPHSTAPAWQAPPRAGRPGPTVPLHAGATDARHAIETVLASWAGMIAQATGAAPPRRVV
                     ADLARFLLARFGLLQRHPAAGDLAAEVAVLVADAERVLRPERGRPLGGCVVPGCKGRLT
                     GGTQPQNLQVTCDADAAHRWDGPEVLMMRDGTPAPAEAVWLDASAITALWGLSRGSVYR
                     LASENGWRRRRRDGRTHYAADDVRSTLG"
     gene            complement(23286..24185)
                     /gene="sibS"
     CDS             complement(23286..24185)
                     /codon_start=1
                     /gene="sibS"
                     /product="SibS"
                     /protein_id="ACN39742.1"
                     /transl_table=11
                     /translation="MTVSFEIVGIFGTEPGGGSPLAVVHDAGGLSTEQMRWIAGRLRAD
                     ETVFVLPPATSGATYRVRVFTAAGESPYGGHSAVGTAVSLVRRGDIRPGTVVQECGGRQ
                     LTLRAGADRAEFAATGTPRVESLPADPVLDAIGLAAADLAGEPVLAGFGPLFRMVPVRQ
                     EALGRARPDFPAMTRHELPEIFLFAWDGPAASAEARLFAPGWAIPRDPACASVALAFGA
                     WLADRQGRPDAPRPFLIRQGAELGRPALLSGTLGAGSGDAEITVTVGGPAPGELAGQIT
                     ASPPDASQPNVLRTSSAA"
     gene            complement(24182..25060)
                     /gene="sibT"
     CDS             complement(24182..25060)
                     /codon_start=1
                     /gene="sibT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083:oxidoreductase (Score: 205.2; E-value: 2.4e-62)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative F420-dependent reductase"
                     /product="SibT"
                     /protein_id="ACN39743.1"
                     /transl_table=11
                     /translation="MRHGVLILPEHHWPRARNRWMLAERLGFAHAWTYDHLMWRWFAER
                     PWFSAVPTLAAAAAVTGRIGLGTLVASPHFRHPVSFAKELVSLDDIAPGRMVCGVGAGA
                     PGFDESLQGGPVLSPRERADRFDEFTSLLHRLLHEERTTYTGRWFSAHDAVVLPKPRAM
                     PLAVAAAGPRGMALAARHADIWVTSGPPNVFEQDRFDRVAPLLKAQTAALDEACAAIGR
                     DPAGLRRLLLTDGAVGGVLESTGSYADASGLFADLGFTDLVVHWPRPAPPFEGDEQVLL
                     DFASAHLQGDG"
     gene            complement(25060..26013)
                     /gene="sibU"
     CDS             complement(25060..26013)
                     /codon_start=1
                     /gene="sibU"
                     /note="putative tyrosine hydroxylase"
                     /product="SibU"
                     /protein_id="ACN39744.1"
                     /transl_table=11
                     /translation="MTGVMLLDDRVQAWDFGDFPYGLEPLTMPLAGKARALAGVVAPEV
                     PPCDVDHVCAELRLLDGGTRDAGRFDLASPATYEQLFWFRWITGHQVTFALWRLMGALL
                     AEHPTDGAPPGPDVLERLETYVHGYGAMLLYSGSCPRDLYSTLIRPAMFRQHRGFSGTW
                     APDFHQVRSLLRGRSRGWLRERSAAGVRAAVEAHCAIHEEVAARLVPEGRSLLQESIGE
                     APVRPSQRTAVLYDNFFMTLRAPISDGTVAVQLLRRLRAVALDLAANGLYPLGRDAAVD
                     ETPAAAAMVAHGERRLGRVVTAIASYAAEVAWRQGT"
     gene            complement(26010..26465)
                     /gene="sibV"
     CDS             complement(26010..26465)
                     /codon_start=1
                     /gene="sibV"
                     /note="putative L-DOPA 2,3-dioxygenase"
                     /product="SibV"
                     /protein_id="ACN39745.1"
                     /transl_table=11
                     /translation="MPLRAHHVGVQTADLDNSVRWYTEFFGARVAWELDRFSDLTLSRL
                     PGIRRLVEVSMEGLCVHLIDRAGHTGQLPPAEGYQFQHVCLQVSEPEQLEVLRDHWIEL
                     YESGRFSFARTDPPTDIVVDADGVSSVYLFDPNGLEYELTHVPDGPR"
     gene            26924..28399
                     /gene="sibW"
     CDS             26924..28399
                     /codon_start=1
                     /gene="sibW"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 125.4;
                     E-value: 7.1e-38)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative FAD-dependent oxidoreductase"
                     /product="SibW"
                     /protein_id="ACN39746.1"
                     /transl_table=11
                     /translation="MISRRGFLGASAVAVVGFDLFGHRWVTAAEAAAGPSFAKAPPLSG
                     ELAVDAAAREAVGTDLGNIVHRRPAAVLRPGSAADIAAMIRFCSAHGIPVSARGQAHTT
                     YGQGLSTGLVIEMRHLNRIHRINDRFAEVDAGILWKDLAGAAYEQSPPLTPPVLTGYTG
                     LSVGGTLSVGGVGGIVGGLRTGLQVDHVQELEVVTGAGVIERCSRQRKPDLFDAVLGGL
                     GQCAVITKAVIQLVPAPQRARNFVLQYSDNAAFFRDLRLLIDRTQVDHVYAEFTAPDPE
                     PVYKIHATAFYDAPATPDAAAILAGVSAVAVVEDTPYLDYVLTIDRLIDFLRETEDWDR
                     LVKPWYDVWLSDSTIEQYLAELVPSLTPRDIGPYGAGLIYPQRRELTTRPAPRRPAPDG
                     SSFVYVVDVNTVSSAPGPDPAFSAEMLERNKRLYARARRSYGAVLYPIGSVPFTEQDWR
                     DHYGSAWPAFRAAKRRYDPAGVLTSGPGIFRRS"
     gene            28492..29664
                     /gene="sibX"
     CDS             28492..29664
                     /codon_start=1
                     /gene="sibX"
                     /note="putative transcriptional regulator"
                     /product="SibX"
                     /protein_id="ACN39747.1"
                     /transl_table=11
                     /translation="MSGEDHQRQGLLHAALDRLRCRLPSLAAATVQAVRRHGDAPPAPA
                     ADGALRTIVHHAALWVLEAVDDRTDPAHIGEAGLLNRTHHSLTAPLVSQACNDMCRRTW
                     QALVQEATAEEGQLLLERSARYLAASTELVEHVLTEQSAAAGSETRLREMATRLLNGER
                     PPASLSAEGGTADTYAVLAVPTQRPGEIAGIAARHHWLSAEQPGAVTVLVPVGGPGRRA
                     DGRARARHAFHALCPQHPVGLGLPADVEGIPAAVADAWEAVATLRRLGRHEPGLFQLDD
                     VLLEAMLCRAPELAARLAGRLRPVTRCQPYLLDTLAAFLDNDGDRRELARQLYIHPNTL
                     NHRLRRVSELTGLSLANAGDLCLLKAALTAWQVTNAAAGAGTGRPAFRAA"
     gene            complement(29675..31468)
                     /gene="sibY"
     CDS             complement(29675..31468)
                     /codon_start=1
                     /gene="sibY"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1274:gamma-glutamyltranspeptidase (Score: 576.8;
                     E-value: 7.6e-175)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative gamma-glutamyltransferase"
                     /product="SibY"
                     /protein_id="ACN39748.1"
                     /transl_table=11
                     /translation="MLSRPELHGTYGAVSSTHWLASAAGAAMFDRGGNAFDAAVAAAFV
                     IQVVEPHVNGPAAEAPIMVHDASSGEVTVVAGQGPMPRRASIETFRRLGLGYVPGSGLL
                     AACVPGAFGAWMTVLLRHGRLRLADVLEPAIGYAEGGYPLLAPAAAIIEALTPLFREEW
                     TETGRIYLDRGAAPRAGSLVRNPDLAATFRRIVREASAPGRARESEIEAAVDVFYEGFV
                     AEAIDAFMCSAEMLDATGKRHRGLLRGEDLAAWRPAVEAPVTAGYRGRLIHKPGPWTQG
                     PVFLQQLALLEGFDLGSMRHLGPDHIHTVVEAAKLAFGDREAWYGDPGHVDVPLRELLS
                     PGYTEQRRALIGDRAAAGLRPGSPLGREPWLPPLPDETAPLEPEWMNQLAHGIPAVVRR
                     TSQNRDTTCISATDRDGNMVVATQSGGWFSSSPAVPGLGFALSTRGQMAWLVEGHPNSL
                     APGKRPRTTLSPTIVQDGSGEPLLAFGTPGGDQQDQWTLNFALNSIDFAMTPQAAVEAL
                     TFHTGHVPSSFMPRQTPPPVVVVEEGLPAETIAALEGRGHRLQQVAARSLGKVCATGHT
                     GDGLVFAAASQRGQQAYGIVR"
     gene            31703..32713
                     /gene="sibZ"
     CDS             31703..32713
                     /codon_start=1
                     /gene="sibZ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 74.9; E-value:
                     1.2e-22)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative methyltransferase"
                     /product="SibZ"
                     /protein_id="ACN39749.1"
                     /transl_table=11
                     /translation="MREWQDFQLSGMPQLISAMHLCQAVHALAETGLLAELRAGLSREH
                     IDSLSGLDPELVRGFLSYLVVRGVVDDLPDGYRLSRRGELLTTDVSLARLGVYAGAYGA
                     VTARTGDLLTGRARYGVDVHRDGGALGRHCATLFEVFHSETIRTATERRGIRTMLDAGC
                     GAGQLLIDACRRDERLTGIGLDNSPEAIAVAEKLAREHGVADRIQFFVADAFEPETWPE
                     ACRDADAMCIVSALHEHFRHGEDAVIELLRRYAGALPALEMLLVGEPELLYEDRENHDD
                     FLLVHVLTGQGLPRDRNAWLPVFEKAGLRCEHIYMRPGAGPRLCFYDLNPRTQRH"
ORIGIN
        1 gtggcggagg gtctgcgcga tgacgtggca cggcacaact actccgtcga catcgcgacg
       61 accgggcgag cggtgctgga ggccttcacc tcctacgatc tcatcctgct cgacaccgac
      121 ctgcccgacc tcgacggcgt ctccgtctcc cgcgccatcc gccagaccag catgatcccc
      181 atcatcgcgt tcgcgtcggc ggacgaggtc gaccaggtgc tgctgctcga gacgggctgt
      241 gacgactgca tcgagcggcc gtaccgctcc cgcgacgtgg tcgcccgtat caatgcggtg
      301 ttgcgccgca cggcgccgat cacctccccg gtgcctttcg cctccccggt gcctttcgcc
      361 tccccggtgc ctttcgcctc cccggcggcg gacctcgaca gcgtcgtccg ggctcggccg
      421 cggggtgtgc cgccgctggc cgccgtgggg gaggacctgg tgctcgggga ggagcagggc
      481 cagctcatca gggtgggcaa ccggctggtc atcgacccgg ctctccgcga ggcccgtctg
      541 ggcggtgagc tgctgacgct gacccgcaag gaatacgaac tgctccacct gctggcgtcg
      601 gcgcccggcc ggatcttcga ccggaccgag ttgatgatca agatctggga ctacccggcc
      661 ggcaaaccgg tcaacgccca ggccagtcgc accatcgaca cgcacgtcag cagcctgcgc
      721 cggaagctcg gccatcgcga ctggatcgcc aacctgcgcg gcgtcggctt ccgcctcgac
      781 gtgccgggtc cacggcgcgg cggccggcag gcgccatccc ggctggtggc cgcggacccg
      841 gaagaggcgc cacggcacgg ctggatcagg gccgaaggcg ccatcgagtc tgcttgacga
      901 tgtccttacg gaaaggcgaa gaccgtccgg ggaagcgacc cgcatgcccc aggcccggcc
      961 gatggccccc tcgtacaggt cgccatcgac cttgtaatcc cacgccgcgc cgtacttggc
     1021 gcggaaggtc tcggcggccg actccagggc cgcggcatcg gtgacccgga ccgcctcgcc
     1081 ggtgacggtg atgtccacgc cctcgccgag gacgttcgtg ccggtcagca tcgtgcagtc
     1141 cgggttggcc cggatgttgt gcatcttctg ctcggtgggc agggcgcaga accacagggc
     1201 gccgtcgtgc caggcgccgg cgaccggggt cacgtggggc gtcgccggcg gccgcacggt
     1261 cgtgagccag tacaactggg ccccttcgag cagggtgcga gtcgcgtccc agtcgtcggg
     1321 ctccgcgccc gggtggctgt agcgagggtc cacggtgacc tcgtacgggg tgtcggacat
     1381 cagtgctctc ccttcgcggg cgtggcggtc agggccagcg ccggttcacg cgtgtcgtgt
     1441 tcgtccagtc cacgccggac ctcggcgtac gaggagatga tcgtctccgc ctcggtgtcc
     1501 gggtcgtaca gctcgcagag ggtgtcgagc gccagcttgt cgatccggct gcggcggatg
     1561 atctcgtcgt agggcgtccg ggtgaacgcc accagctggt acagctgggt gaactcggcc
     1621 gggcggtact cgtgcagcat gcgttccaga cgctggcgcc ggtggaagcc cgcgtcgtcg
     1681 atggacttgc tgagctcgtg cagattgtcc atggagagct gagagatcgc ctggccggcg
     1741 gccacccgct gctcgctgaa ctcggcgccc gccgcccgga tcgcctcgtg ccggtccacg
     1801 ccggaccgcc agtacttgtc cagcagccgg cacaggatgt cggcatcctc gaagctgcag
     1861 ttgatgccct ggccgaagaa cgggacgatg gtgtgcgcgg aatctccgac cagcaccgcc
     1921 cggccgtaat tgtagggcgc gcaatcgacc accttgagca gcgccgggcg ggcgcggatc
     1981 acctcgtccg ccgccagcgg caggtggggc gcgatgtcgg ggtactcccg ctcgaagtgc
     2041 tcgcgcaccg cctcggtgcc ggtcagggag cggaagcgca gctcgccgcc ctcgttgccg
     2101 accggcatga aaagggtggt ggtggtgctg ccgtcccggt tgggctgggc ctgaaggaag
     2161 tggtcgctgc gtggccacag gtgcatgccg tccggcgcca gcgcggcgga cccctccggg
     2221 gtgagggtca gctcgacatg gccgtgcgcg atgtagcgct gatggacctg catgcgagcg
     2281 ccgcccttgg acagctcgta gcgcagagcg ctgttcgcgc cgtcacaccc gatgagaatg
     2341 tcaccggcgg cgtggcggac cgtgccgcga ggatcgacga acatcgcctc gccgcggtgg
     2401 gcgtcggcgc cgacacagga gtggccgaag aacatccggg cgcccgaggc gcgtgcctcg
     2461 gcgagaagga tgcgctggag ttcgcggcgg ggcaccgaca gcaggtgctg atcgtcgctg
     2521 atcccgtacg gctggcgggt cagcgtgccg tcagtgtgat gcacgatgcg ttgccgcagg
     2581 acgctgccga tctcgtagac gcggtcacgc aaccacgggt gcagcacgct gagtccacga
     2641 tgggtcaggg tcaggttgaa cgagcggccg acgccgggcc ggagcacggt gtccgcgtcg
     2701 cacttctcgt agatctcgac gtcgaagtcc cggcgccgca gttccaccgc caggaggcag
     2761 ccgacggggc cggcaccgac gatgaccgct ttgggtggcg ttgctgacat ggagggagcc
     2821 cttcctgagg tcatggcgcc gaggtagggg cgagctgacc ggtctcggtg aagtactcga
     2881 tcatcgaagt gatccacccc ggctctgccg cgggaatctc gagccccagc gcggccaggt
     2941 cacggacggt gcggtcgttg acgtaccggt gttcgctcag attcatgaca ccctcgcgga
     3001 acagcgggac caggctcgcc agcgagttgc cgtcggcgcc ggccggagcg gtctccagag
     3061 ccgcgagcca ctcctcggtg gtcaccggcc gcgggtgatg cccggccgcg gccagggccg
     3121 ccagggtggt ctgccaatcg ataccggtgg gatggaagat gtgcacggta cggttccggg
     3181 cccgggcgga gccgccgagc cggaccaccg cgtcggcgac catgtccacc ggcaggagat
     3241 cgaccggccg ccccaggtcg gcgggaacca cgcccagccg cacgaagctc ttgatctgca
     3301 accagaagaa gtcgtccgtg cggcaggcgc cggtgaccga gtccggcccg attctgccga
     3361 tgcggtacac ggtgaccggt acgccgtgtg cccgcgccgc cagcgccagc cgctcggcga
     3421 cccatttgct ctgcgcgtaa ctgatgccga gcccttcggc ggtcgagggg atgctgtcct
     3481 cgtccaccgt ccggggcggc tcggccggtg agaagaccgc cagtgtcgac atgtggtgca
     3541 acggcttgag cacggtgtcg gcgcagaact cggcgatccg cacgaagccg tcgacgttgg
     3601 aggagcggac cgaggcgtac ggcgcggaga agttgatgtg tgccgcggcg tggtacaccg
     3661 ccccgatccg gccggcgagg tcctcgtagt cggcggggtg aagaccgaac cgttcgaggg
     3721 cgagatcacc ggcgacgacc cggacgtcag cgaggttcgc gtcgacccga tatcgccggc
     3781 aggcctccgc gatccgggcc cggccctgct cctcgccgtc ggcgcggacc aggcagtgga
     3841 cctcgtggcc cgtctgctgc aggactctga gaaggtagct gcccaggaag ccggtcacgc
     3901 cggtgagcag cacggtccgc gaggtacgcg cgtcggcggc gcgggtcgtt ccgagtcgca
     3961 acccgtccag cagacgcgtg tcggcccaca ggtccggtcc gtccacctcg tcgtggccgg
     4021 cccgcacggc gtcgacgcgg gccgccatgc cggccacggt cggcgtcgcg agcagggcgc
     4081 tgagcggcag ttccatcccg aactcgtcct ccaccgcctg acgcagccgc acggccagca
     4141 gggagtgccc gccggcgctg tagaaatcgg tgtccgggcc gatgccgccg ccgggcagca
     4201 gcccggccca caacgcggcg acgcgctgct ccgtctcccc gagcgggcga tcgtcgctga
     4261 cgtcggcggg ccggtccggc gaccggctcg ccagggctgc cagcgccgcg cggtcggtct
     4321 tgccgctcgg agcgaccggc agccggtcca gggtcacgat ccgtgacggc accatgtagg
     4381 cgggcaggga ggcccgcagc cggtcacgca cctgccgtgg gtcgatcagt gtgctgccgg
     4441 tgcagacgaa ggcgaccagg tcgcggccgc ccgcctcgag ctcggccgcc accaccgcgg
     4501 acgcggtgat gcccggcagg tcgttgaggg cgccttcgac ctctccgggc tcgacccggt
     4561 agccccgaat cttgatctgc tcgtcggcgc ggcccaggtg cacgagcccg gccggggcgg
     4621 tgagcatcac caggtcaccg gtgcggtaca tgcgcccgcc gggccggccg gcgtacgggt
     4681 cgggccggaa ccgttcccgc gtctgatcgg gcaggtgcag gtagccacgg cccaccaccg
     4741 ggccgccgac gtacagttcg ccgcgaacgc cgaacggcac cggccgctgc tgctggtcca
     4801 gcacgtacgc ccggacgttg ccggccacct cgccgatggc ggggcgttcc ggccaggacg
     4861 acgggtcgcc gggcagtcgc cgcgcgctga ccaggtgcgc ttccgacggc ccgtaggcgt
     4921 tgatcaggac agccggggtg cagcggcgga acatgtcgcg gatctgcgcg gtgacgacca
     4981 gcgcctcacc ggtggtgtag acctcggcga ggtccggcag gtggatgtcc tcccgagtga
     5041 gcacggtggc cagctcctgc aacgcgacgt acggcaggaa gattcggttc acgcgctgtt
     5101 cccgcaggtg gcccgccagc cggcgcagat cggtgcgcat ctgctcgtcg gggaccacca
     5161 ccgtgccgcc cgcgcacagc gtgcagaaga tctccatgaa cgacacgtcg aaggagatcg
     5221 acatgtattg cagggtgcgg gcggtctcgc cgagtccgga caggtcgtcc tggcggtgga
     5281 cgaggttggt gatggtgatg tcgttgatga tcaccccctt ggggcggccg gtggacccgg
     5341 aggtgtagac gacgtacatc tcgtcgtcgg cggcccgctg cccggccggg tccgtgtcat
     5401 cggcgggcaa ctcgacgctg ccgaagtcca ccaccgtggt gccggcgggg acctcgaccg
     5461 gtgagccgcc gtgcacgagc aggacttcgg ggttcgcgtc gcgcagcatc agcgcgagcc
     5521 gctggggcgg gtacgcgggg tccagcggaa cgaacgacgc cccgctcttg agcacggcca
     5581 gcagcccgac gaccgcgtcg ggaccgcgct ccagccgcag cgccacccgg gtgccgcgcc
     5641 gggcgccgtg ccgccgcaga gcccgtgcca gccggttcgc ggcactgttg agctgccggt
     5701 acgtcagctc accggctgac gaccgtaccg cggtccggtc cggatgctcg cgtacccggg
     5761 cctcgaacat ctgcgggagc gactgccgcg ccgggcgctc gtccaccggc cccgaccacg
     5821 ccgcccgcag ctcacgcagc tcgtcctcgg gaatccaggg aaggtcgtgc acccgctggt
     5881 ccgggtcgtc catcagggcg gccagcacgg tccggaacct cgccgccatc cgggtcacgg
     5941 tgtcgtggcc gagcaccgcc gggtcgtact cgaaggtcag gccgagatgc tcggcggcct
     6001 cctcgaccac gagcgcgaga tcgaacttcg gggtgctgcc gaggtgctgc cacgcgtcgg
     6061 cgccgaggcc cagatgccgc aggtcacgac gttcggccgg catgatcgtc accatcgtct
     6121 ggaacagcgg aggccggccg tcggcacggt ccggcgcgag cctctcgacg atctgctcga
     6181 acggcacgtt cttgtgcgcg agcgcggccc tcacctcgtc cctggtcgcg gtgagcaggt
     6241 ccgtgccggt gctgccgggc gtcacccggt gccgcaggac gaccgtgttg accagatggc
     6301 cgatcacgtg ctggtccgcc gaacggtccc gcagcgagac cggcaggccc acggtgagat
     6361 cgggctggcc ggtgtggcgg tgcatcagca gggcgtaggc ggccagcagg gcgacggcag
     6421 gggtggcccc gtgcgaggcc gcctgccggc gcagccggac cacctccgac gcggtcagcc
     6481 gcgtgtgcac cgacgcggcg gcgaccctgc cgcgcggacc ggccgggtgg tccagcggca
     6541 gatccagcac ggggacgccg gccaggtgcc cggtccagta cgccaggccc gcctcgccgg
     6601 ccgggcgaag ggccgcgacc gcctgccgga actggaccgg cggcgcgtcg tgcggcagcc
     6661 gctcgcccgc cgccgcacgc cggtaggcgg tgagccactc gctgagcagc accgaccagg
     6721 agaagccgtc gaacaccgca tggtgcacgc tgaccagcag gatcgtgttg tctccaccga
     6781 cgtcaacgca gacggcgcgc agcagtggcc cgtcggtgag gtcgaggtgt tcggcggcga
     6841 gctcggccgc gagcctgccg gcctcgccgg cggagccgac cgcggcggtg cggaacccga
     6901 atcgcggctc ggccgccacc agctgcgtca gcgtgccgtc gcgcatctcg aaggtggtgc
     6961 gcaggctctc gtggcgccgg accacatgct ccagcgccgc ccgcagcgcc tccgggtcga
     7021 gggcgcccgg cacacgcagc aggatcggcg agttgtacgc ggtccgcgcc tcgccgaact
     7081 cgctgaggta ccagatgccg gtctgccccg gcgtggccgg ccacgccggg gcagaccgga
     7141 gttccgtgcc gggtgtgccc acggccggca cggagccggt ggtgagccgg gcgaccaggc
     7201 tctccgggct gccggccgcg gcgatgtctt ccgggtccac ggcacgcccg aggatgtcgg
     7261 ccagctccgc ggccaggatc tcggggcgtc ccgacgaggt gcgccagcgg tcgcggacca
     7321 cagtgagcag cacgtcgctc atgcaggcac ctcccggtgg ccctggcgca gggcacggat
     7381 gtgcccggcc aggctctcgg cgttgtcgag ctggaagatg tcctccgggc ggacgtccac
     7441 ccccatgacg tcgtgcaggc tggccgcgag ctggatgacc tgcaacgagt tcgcgccgga
     7501 cgccaggaag gagtcggaca ccccgatcgg ctcgcggccg gtcacgaccg ccagcagcct
     7561 cgtcaccgtc gtggcgatga tgtcccggac cacgggttgc tgctgcgccg tgccgtccgg
     7621 ctcgaccagg accgcacgag gctctcgcag ggccatccgg tcgagcttgc cgttgacgtt
     7681 gaccggcagc tcggcgagat ggtggacccg agcggggagc atgtagtcgg gcagccggct
     7741 cttcaggtcc gccagcagcg cctcgatgct gggcgcctcg ccggtggcgg tggtgcagaa
     7801 caggacgagc tccttctggc cgtcggtggc gtcgacggcc cgtaccaccg ccttctcgac
     7861 caggccgctc tggtcggcgg cgagctccac ctcgcgcagc tccacccgga aacccctgat
     7921 cttgaccatc tgatcggtcc gcccgacgag gaccacctcg ccggcggggg tggtacgcgc
     7981 ccagtccccg gtgcgcagca tccgcacgcc gtcgacggtc gggaacttcg ccgcggtctc
     8041 ctccggcagc ccgaggtagc cctgcgccag gccggcgcca ctgatgtgca tctcgcccac
     8101 ctcgccgggc gcgcacgggg tcatgtcctc gccgaggacg tgcaggccca cccccggcaa
     8161 cggcaggccg atcggcacga caccgagctg gagatcctcc ggggtcatcg ggtgcaccgc
     8221 cgtcagcgcc gagttctcgg tacagccgaa agcgttgtag acggtgccgg gtaccgcctt
     8281 catgacccgc gccaggtggg gcgcggacgg gaagtccccg ctgacgatca cggtgcggac
     8341 cttggcgaac gcttccgggt gggcgtcgat gagcaggttc atcaggccgc ccggcaggtt
     8401 gaggaaggtg acgccgtact ccttgatggt gtgggcgagc ttcggcagcg acggcagctg
     8461 cgacggcagc accacgacgc gggcgccgtg caggaggctc agccagatgt ccgtggtcga
     8521 cgccgcgaac gagtacggcg ccagctgcag gaagcagtcg tccggccgga cctccacctc
     8581 gccgttgtac gacgcgaccc gggcgatccc gcgatgggcg atccgcacgc cgcgcggacg
     8641 gccggtggag ccggaggtga acaggatgaa cgccgtgctc tccgggtcgg tgcacaggcc
     8701 ggggctggtg tcgtccaggt ccgcgccggc ggcgagcagc tcgtgaacgt cccgttcgac
     8761 ggtcaccgag ctcagcccgg ccggcacgtc gcgcagcgtc agcggcagat ccgcctcgcg
     8821 gaccaccgag cggcgcacgg tcaccgggtg ggacgggttc agcggaacca cgacagcgcc
     8881 ggccttgagc agcccgatca tcgcgatgta gagctccagg caccgcgtca tgtgcaggcc
     8941 gacccggctg cccggggtga cgccctcgcg cagcagccgg cgtgcgaagc ggttggcggc
     9001 ggcgtccagc tcgcgatagg tgatcgacga cgagccgtac tccagggcga tccggtcgcc
     9061 ggcggcgcgg gcggccgcct cgaaggccac cggaagggtg gggactcgga gagagggaag
     9121 ggcggacacg attcctcctg cgcagcatcg aatggccgcg gcagcggagc tgcggcagcc
     9181 tggagtcggt gatgaggcgg tggtcttagc ggggcagcgc tgcccgcaga tagtcggccg
     9241 tgcgggtgcg gcccttttcg gccatgtcgg cgggagtgcc ggtgaagacg acctggccgc
     9301 cgtgttctcc ggcgccggga ccgatgtcga tcacccagtc gctgtgtttg acgacgtcga
     9361 ggtcgtgctc gatcgcgatg accgtgttcc cggcgtcgac caggcgatcc agcagggcga
     9421 gcaggttctg cacgtcggcc atgtgcagcc cggtggtggg ctcgtcgaac aggtacacgc
     9481 tgccgctctc gtgcaggcgg tcggcgagtt tgagccgctg gcgctcgccg ccggacagca
     9541 tggacagggg gcgtcccagg gtgagatagc cgagcccgac ctcacgcagc ggctccaggc
     9601 gcttgacgat ggcccggtcg tcgaaccact cgcggctctc ctccacggtg agatccagga
     9661 cctcggcgat gttgagcccg tcgatgcggt gttccagcac gtcctgccgg taacgggtgc
     9721 cgccgcagac ctcgcagacg accgtgacgg ggtccatgaa cgccaagtcc gtggtgatgg
     9781 tgccgcggcc cttgcactcc gggcaggcgc ccttggcgtt gaagctgaac aggctgatgt
     9841 ccacgtggtg ggccaccgcg aactgcttgc gcacgaggtc ccacacaccg gtgtaggtgg
     9901 ccggcgtgga gcgcgggttg ataccgaccg cggactggtc gagcacgatg gcgtacgggt
     9961 actcggcagc gaagaccttg gaggccagcg tcgacttgcc ggagccggcc acgccggtga
    10021 ccacggtgag caccccggtg gggaagtcca cgtcgacgcc gcgcaggttg tgcagggtcg
    10081 ccttgcggat cggcaggctg ccggtcggcg tccgcgtctc cggcttgagc cccggcaggg
    10141 ccttgaacga ccggccggtc agggtgtcgc tggcggcgag ctgtttgacg gtgccggtga
    10201 agatgatctc gccgccggag gcccccgggc cggggccgac gtcgatgacg tggtcagcga
    10261 tctcgatgac gtcacggttg tgttcgacga tcagcaccgt gttgcccttg tcgcgcaacg
    10321 cggtcagcag ctggttgagc cggtccacgt catgggcgtg caggccgacg ctgggctcgt
    10381 cgaagatgta ggtcatcccg gtcagcgagg atccgaggtg ccggaccgtc ttcaggcgct
    10441 ggccctcacc gccggagagg gtgcgggtgg gccggttcag ggtcagatag cccaggccga
    10501 ccgactcgat gcggcgcagg gacgcgagcg cggccggcac caccgggccg ggccagcgtt
    10561 tctcgagccg caccagctcc gtcaccaggt cgccgatctc catggcgcag aagtcggcga
    10621 tgttgtgccc gtcgatccgc gacgccacgg cggcggggct cagccgcgcc ccttcgcagg
    10681 cggggcagac ctgctcggtg acgaccttct cggtggcctt gcgctccttg tccttcagcg
    10741 agtcgaggcc cggcttgacg aaccggcgcg tgaaccgcag gaccaggccc tcgtagtcgt
    10801 tgacagccac gttgttgaac tcgtccggcc gggtcgtctg gaagccctcg ccgtacagca
    10861 gcaggtccat ctcggacttg gtgtagcggg ccaacggctt gttcgcgtcg aacagcggct
    10921 ccaggtcggc gcccctggcc ttgcccgcct cgaaccgggc gacctgggcg tagcgcttcc
    10981 agtagttggt gccgacggcg aagttggggt gctggatcgc gccctcgttg agcgacaggt
    11041 tcttgtcgag cagccgctcc acgtccagtt gcagggtcgc gccgagaccc tcgcactcgg
    11101 ggcacatgcc ctgcgggtcg ttgaacgagt agaagttcga cgggccggcg ctgggctcgc
    11161 cgtagcggga gaacatcacc cgcaggatcg ggctgacctc ggtcatcgtt cccacggtcg
    11221 agcggttccc gccgcccacc gccttctgat cgaccacgat ggccgggctc aggttctcga
    11281 tcagctcgaa ctcgggccgt tcgtagcggg gcagccggtt gcggatgaac gctgggaaca
    11341 cctcgttgag ctgccgctgg gattcgacgg cgatggtgcc gaacaccagc gacgacttgc
    11401 ccgagcccga cacaccggtg accaccgtca gtttgcccag tggtatccgc aggtcgatgc
    11461 ctttgaggtt gttggtgcgt gcacctgtca ccacgatgtg ctgcctgtcc gctgccatag
    11521 cgtccgggtc ctcccaatca tgttgctgtt cgatcgatgt gcgttcaccc gcgtacgggt
    11581 accgctccac tgccctcggt tgccaggtcc ctccaggaga tctggccacc gcgagtggcc
    11641 agatcgtcca gcaaccgttc catcggtacg tccggcagcc gcgtgaacca cgtggcgctc
    11701 agccgcccga tacgttgagt gtgttccaca atggggcgcc gtgcgtcctc gtaccccttc
    11761 agggcgtcgg cgagccgcgg ctgcgcgcat agggcgtcgg cgagcgccct cgcgtcgtcc
    11821 agcgcgagcc gggtccccga gccgatcgag tagtgcgcgg tgtgtgccgc gtccccgatc
    11881 aggaccacgt tgccggccga ccatgtgcgg ttgtggatct cctggaaccg gctccaccgt
    11941 gatctgttct cgagaaggcg ggctccaccc agcgggccgg cgaaccactc ggccaggacg
    12001 gcaggcggtg gagctccgtc cgcctcgacc aggaaggtgc tgcggtcggg ggagtacggg
    12061 taggcgtgcg cgacagccgg gccgtccggc gtctcggcca ccaggaaccg caagtgttcg
    12121 agggccctgt cggcgccgag ccagatgtag gccgggccga tctcgcgggt ggtggtgccg
    12181 aaggccgccg cccggtgccg gcgggtcacc gaccgggccc cgtccgcggc caccaccagg
    12241 tcatggtcgc cgagggcggg atccacggcg ccgtgctcga accggacgcc ccgttcggcg
    12301 catcgacggc gcaggacctt cagcagggta cgccggtcca tggccccgag acggggggcc
    12361 gggatggacg ccgtccgtcc gtgccggtgc acgctcagcc ggtcccaggc cgtgatgtgg
    12421 ctgttcaact cgtcggcgag gtccggctcc gcgtcgcgga acacctcgac cgcggccggg
    12481 ggcaggatca ccccgaagcc gtaggtgtcc ccggggccgg tccagtcccg gacggtgatc
    12541 tcgtcgccac ggccggaccg ggcggcgaac atggcgaacg ccatcccggc ggggcccccg
    12601 ccgttgacca ggatcctcat cgactgtcct ggatcaactg gctgatccgg ttgatcaccg
    12661 acgcggtggt cggcatggtg gccatctcgg cggccacctc ctccgccgcc cggcgcggcc
    12721 ccggatcacg caggaccgcc tccagcgccg cggtgagcgt gtcggggctc acctcgctga
    12781 ggttcacggt cgggcccgtg ccgcgggcgg tcagcgagcg ggcgttcgtc atgttcacgg
    12841 tgcccggcat cggaagcgtc acctggggaa gcccggcggc gagtgtgctg aggaaggtgc
    12901 ccgatccgcc gtggtgcacg accgcgtcgg tggtgttcaa cagcgcccgc agcggcagcc
    12961 agcgctccga gcggacgtgc ggcggcagct cggacggcag ctcgggcagg tccgcgtcgg
    13021 ccgtgagcag gatcagctcg gcgcccagcc gctccgtggc ggtgacgatg tcgcgataga
    13081 ggcgcccgtc gagggtcatc gcgggggcgg agccgcaggt ggcgaccacg cgcgggacat
    13141 cgccgcgccg cagcgcccag tgcggcagcg tgccgccgtt gttgaagcag ccgtaccgca
    13201 tggcgagcgt gtgctgcggt ttgccgatgg tggtgggcac gtcggtgaag ttggccagcg
    13261 agggaggcag gacgtcgatc tcgaactccg cctcggtgac cgtgtcgaca ccgaaccggg
    13321 cggcgtgcgg ggccaggtgc tccagggacg gctcgaaggt gggcagcggt gtgccgtagc
    13381 cgtgcagcac ggcagggatg ccggccgccc gggcggccac cagggcggcg gcatggatcc
    13441 cgagatacac gacggcgtcg gcccgccagt cccgggcgat ggtgacgatg tcgtcgagtt
    13501 gccgggcgcc gacctccccg aactgcctgc cgtgcacggc cagcgaagtc gggtcgtcag
    13561 gggccacacc cgcttcaccg cgggcgagca tgtccagcag gtcgtcgtac ggttgccggg
    13621 cctgccggct gccgccggcg tcggcggtga ccaggccggc ggcgaccgcg gtacgggtgg
    13681 ccggccccga cgtcgccacg agcacgtcgt ggccgccgga cagtgcggcg tgggccagcg
    13741 gcaccagcgg catgaagtgc gacgcgaccg gcatggcggt gaacagatag cgcatggtca
    13801 gctcctgaag aggccggcgg gggtgggaac cagcggcttg gtgtcgccgg tgtgctcggg
    13861 cagcccgatg gggtcggtca tcgccgccgg ggccgacgtg ccgtccgaca cgctccaggt
    13921 ggccggcggc ttgtccgcga tctcggtcag ataggcgccg tagtccgtgt cagcgtgctc
    13981 gcggccgagc cgctggagcg cggcccggtc gatgaacccc atccggaagg cgatctcctc
    14041 gaggcaggcg atgcgtacgc tctgccgctg ctccaggatg tgcacgtact gcccggcctc
    14101 cagcagcgcc tcgtgggttc cggtgtccag ccagacgaag ccgcggccga gctggaccag
    14161 ccgcgccttg ccccgctcca ggtaggcgcg gttgatgtcg gtcacctcga gctcgccgcg
    14221 ggcggacggg cgcaggccgc gggcgatgcc gacgacatcg ttgtcgtaca tgtacaggcc
    14281 ggtgacggcg agctcggagc ggggccggtc cggcttctcc tcgatgtcgg tcaggtgccc
    14341 accggagtcg acgacggcga caccgtaccg gtgcggatcg cgtaccggat atccgaacag
    14401 tgtgcacccg tcgacccggc gggcttgttc gcgcagcagc gcggagaaac cgggaccgtg
    14461 gaagatgttg tcgccgagca cgagcgagac gctgtcgtca ccgatgtggc cggccccgat
    14521 caggaacgct tcggcgatgc cggcgggacg gtgttgttcg gcgtacgtga gccgcatgcc
    14581 gagccggtcc ccgtcaccca gcatcgcgcg gaacagtggc aggtgctgcg gcgacgagat
    14641 gatcagcacc tcggtgacgc cggccagcat cagcaccgag agcgggtagt agatcatcgg
    14701 cttgttgtag acgggcagga gctgcttgga gagcactccc gtcaaaggtt tgagccggga
    14761 cccggagccg ccggccatga tgatgccctt cacgtctcgt cctcctcagc gggtccggtc
    14821 cggtacggcg gcagcagccc tcggccgagc gcctcggcca gggtgggggc ggcgcggtcg
    14881 gccggggaca tgaccagttc ctgcgccgcc ggcagcggca ggccgagggc ggggtcgagc
    14941 agcgacaccg gttgttcgtc gccggcctgg taggcggtgg tcatcaggta gctgaccacc
    15001 gtgccgccgg tcagcgcgac gaagccgtgg cccaagcccg cgggtaggta cacggcccgc
    15061 ggcagatcgg cgtcgagcag gatggtgtcc cagtggccga aggtgggcga ccccacgcgc
    15121 acatccacga cgaagtcgat cgcactgccg gagacacagt gcacgatctt ggtggggccg
    15181 tcgccgccgg gcgcgtagtg gatgccccgc gccgccccgg cccggttgac gctcagcgcg
    15241 ctgcgccgga tcgggaacgg cacgctcagc gcgccgtcct ggtagatcgg gcagaacatc
    15301 ccccgctcgt ccgggaacac ggggagggtc agctccagcg cgccgtccac ggcgagttcg
    15361 cgtgtcttca tggcgctccc ttcggctgtg cggcacggac cacggcggcg cccagcacgg
    15421 tcgccgggtc gccgaggtcg aacggcagat cgaagtggtc ccggccggcg accacgagct
    15481 cggtgaccgg cgtcgcggcg agacgcagcg cggcggcgta ccggcgttgc tggccgtggt
    15541 actcgcgggt ctcgtgttcg cccacggcca gcaggaccgg cacggcaggt ggcgggcgca
    15601 gcatcgggct caaccgcgcc gcctcttccg cggtgagccc gagcgcgttg ttgacgtagc
    15661 tgccgatcac cgggctgagg tcgtacaggc cgctgaggag gaacaatccg gccagcggca
    15721 gatcggctgc catggctgcc aggtgtgccc ccgcggagct gcccgccgcg aagaccgcat
    15781 ccgggcggcc gccgagctcc tccgcgtgat cgaggaccca ggtgaggccc cgccggaccg
    15841 acgcggtcat ctccggcagg cttcgctgcg gcgccaggcc gtagcccagc gccaggtagc
    15901 cgaacccggc ggcgatcagg cccggcgccg gaaaacaggc gtcctccttg ctcgactcct
    15961 gccagtgacc gccgtggatg aagatcagca gtggtgagcc gggccggcgc ggcgggaaat
    16021 ggtgcagcac ctcggccggg tgggacccgt accggagatc ggcgtggtgc acgaggtcgc
    16081 ggcgcgcggc ctggctgcgc aggcggtacc gggccagggt caccggcgcg tcgcgggcca
    16141 cggtgctcgg cgacagctgc cggtcgagct ccgtacggac ggatgtcatc gcggacggct
    16201 ccccgacacc accccgtgcg gggtccagcc gggtggcgcc gtccggccga catcggtgaa
    16261 cccggcctcg cgcagccagg actcgcagtc cgcccaccgg tggatcgtcg aatgccggaa
    16321 cggcagcgtg gtgaagtaca cgttgtcgag ggcggcgtac agcgggccgg tgcggtcgtc
    16381 gtcggtgaag gcgttgaaca ccaggacgcg cccgcccggt tcgaccgcgt cgtacgcctt
    16441 gcgcagcagc gtcaggttct gttccggaga ccagatcacc agctggtgag cgaacaggac
    16501 acagtcgtgc ccggccgggt acgagtcggt gaagatgtcc gccgcgtggg tccgcacccg
    16561 ctcctcgagc cccgcctcgg cgatggtctt gcgcgccacc tccagcgcgc ccggccggtc
    16621 gagcacggtg acccgcaacg acgggtgggc gcgggcgagg gcgacggcgt tgaccgcgtc
    16681 gccgccgccg acatcgagca cccggtgcac gcgggtgaag tcgggctgtg cgagcagcac
    16741 cgggttggac agctgcgacc aggcgtgcat tccccgatag aacagctcct cgaggcccgg
    16801 caccgcggcc agccgcgagt acaggtcacg ggtcgtgccg gggaagtgcc ggatgcccgc
    16861 gttctgcccg gtgcgcagcg actcgacgta gtccgccgcc ggctggtacg cgatcttgtc
    16921 ctgatactgg acgatgtcgc gcagcaccgg ccacaggccg tcgcggaagg cggcgccgat
    16981 gggcgccccg ttgcggtaac cgccgtcggt cacggtgctc agaccgagcg cggtggtgcc
    17041 tagcaacagg atgtcggctg agcgccgggg gagccggagc gcgtcggcca cctcctcggc
    17101 ggacaggggg ccgcgttcgt ggagcagttc gaacaggccg agctggcagc ccgcgttgag
    17161 ctgctggaac gcggcgtgac cgaacaggac ggggacgagg gcggacagtt cggagctcac
    17221 tgccggacct tctgccgggc gtacaccgcc ggttccggca ccgggatgat gaaggcgccg
    17281 ccggcgtcca ggaaggcggc ctcccgctgc aggatctcct ccgcgtagtt ccaggccagg
    17341 agcaggtaca ggtcgggttg ctcggacacg tcgccgggcg ccacgatcgg gatctgcgtc
    17401 ccggggacga accggccctg cttctgcggt gtggtgtcgg tgcagaatcg cacctcggtg
    17461 ctggtcagct cgcagatgtt caacagcgtg gtgcccttcg cggaggcgcc gtacccggcg
    17521 acccgcttgc cgttggcggc ctccttgcgg accagttcgg tgagttcccg gcgcagggcg
    17581 tgcacccgcg cggcgaactg ctcgtagcgg gcgtcggtgt ccaggcgctc gctcttctcg
    17641 tacgcgatca gctcgccgac ccgctcgtca gtctcccacc ggctccccat ccgagcggcg
    17701 gtgaccagca cggagccgcc gtgcacggcg agccggcgca cgtcgatggc gcgcaggccg
    17761 tgccgggtga acagccggtc gagggtgctg atcaagaagt aggagaggtg ctcgtggtag
    17821 atggtgtcga aagcgacccg ttcgaggaga tcgcacgcgt acggcacctc gatggcgaac
    17881 aggccgtcgt cggtgagaag cgctttcaca ccccgcagga cgtctgccag gtcgtcgatg
    17941 tgggcgaaga cgtgccggcc gaggatgagt gacgcccggc cgtgctcgcc ggcgatcgcg
    18001 gtggcgacct tctcattgaa atagtcggcc acggtcggga cgccccgccg ctcggcgatg
    18061 gcggcgaggt tctgggccgg gtcgacgccg aggaccgggt gcccggcctg ctggaacagc
    18121 tgcagctggt tgccggtgtt gctgcccagc tcgaccacga ggccgcccgc gtcgatccgc
    18181 tcccggcaga gccggacgac gtcgcgcatg tgatgcgtca tcgtctcgga ctccgaggtg
    18241 acgtatgcgt agtcacggta gagggcctgc gggtccacca cggcggtcag gctgagaagg
    18301 cggcagctgc ggcaggagat cagctccagc gggtaggcct cttcgggtcc gggcttgtcg
    18361 aggtaggcgt tggccagggg aacggagccg aaggagatga cctcctgcca gtcggcggcg
    18421 ccgcacacac ggcaggtggt gacagacttc gcgatttccg tggtcacggc tgactccctc
    18481 gggactcgga ggtacggaac gagacgacgg cgtccacaac ctgctccacc tgcgccgggg
    18541 tgagaccggt gtgcaggggc agccggacca gccggtcggc gacgtgttcg gtgatcgggc
    18601 agccgccggg cacggtacgg ccgtaccgct ggccggcggg tgagttgtgc agcgggacga
    18661 agtggatggt ggcggtcacg ccgcgggctc tcaggtgatt caggaacgcg gcccggtcgg
    18721 cgggctcggg caggacgagg tggtagaggt gcgcggagtg gacgcggtcg gcgggcaccg
    18781 cgggcagctg gacccgctga tccccggccc actcggcgag tccttcgtgg tagcggtacc
    18841 agacggcgcg gcgctgtcgc tgcacggcgt cgtgttcctc cagctgggcc gcgagcaggg
    18901 cggccagcaa ctcggggagg atgtacgagg agcccaggtc gacccagcgg tacttgtcca
    18961 cctggccgag gaagtactgg tgacggttgg tgccgcggtc gcggatgatg gtcgcccggt
    19021 cgaccatgcc gtcgtcgttg accagcagcg cgccgccttt ggcgctgtgc acgttcttgg
    19081 tggcgtggaa gctctgcgcc gccagcctgc cgatgctgcc cagcggccga tcccggtagg
    19141 aggcgccgag gccgtgcgcg ttgtcctcga gcacggggat gccgtggcgc tcggcgatgc
    19201 gcatgatctc gtccatctcg caggcgacgc cggcgtagtg aacggcgatg atcgcgcggg
    19261 tgcgttcggt gatcgcctcc tcgagggcct tctcgtcgag gttgagggtt tcggggtggc
    19321 agtccacgaa cacgggtacg gcgccacgca gagcgaaagc gctggctgtc ggcgcgaagg
    19381 tgaacgacgg catcaccact tcgtcgccgg gcgcgaggtc gagcagcagg gcggcgatct
    19441 cgagggcggc ggtgcacgag ggggtgagca gcacctgccc ggcgccggtg atccgctgga
    19501 tcagagcgga ggcgcgggcg ctgtagtcgc cgttgccgtc gagatcgccg gacacgagcg
    19561 ccgagctcat gtactcggcc tggtgccggg cggtgtgcgg cacgtggaac gggacggtgg
    19621 gcgcgacggt catcggacca gctccagcag cgtgaagtcg atgtgcacac gggcgtcgtc
    19681 gccggcgtgc tcgcggtaca ccggtgaggt gccgagctct tcgggcgcag ccgcgaacga
    19741 ctcctgaacg tggatgcgga cgtcgaggcc ggcggcggcc gcggcatcgt gaagccggtc
    19801 gccgctgccc atcgcgaaac tgaacccgag gaacagccgg ccggccgggg tgagccggcg
    19861 gcgggcctca cgaaggaacc gctcgtgcat cgtgtagccg gggtcgaaga agtggtaggc
    19921 gaggtcggag tcgagcgcgt ggtcggcggg cacctggatg aacggcgagt tccagaagat
    19981 caggtcgtag gcggtgtcct cgggcaccgc cgagaacagg tcgctgacca gcgcggtcac
    20041 ccggtccgcg acgccgtggc gctcagcgtt gagctgggcc gtgcgtacgg cggcggggtt
    20101 gatgtcgagg gcggtcaccc gcggcacgcc ggcgagcgcg cccaggacgg cggcgactcc
    20161 gcagccgcag cccatctcga gcatcgagtg gacgccgtcg tacggcaggg acgaggcgaa
    20221 aagtccggtg gcatagttgt actcgccgcc gacgaccccg ctcagctggg tccatgtcct
    20281 gtccagcagc tcgaattctc gggtgtcgtc actgcgcagg gcgtgttcgt aggcttcctc
    20341 gcccatggtg aggccgagtc ggttcattct gatcccctct cgatggaacg ggattgctgt
    20401 cacagggcgg agcgcgccgt ccacagctcg gcgaagaatc gatgctcgtt gatctttcgt
    20461 agccaggcgg cgccgtccgt gccgccgagc ccgcgctttc cgccgatcat gcgctcgacc
    20521 accagcaggt gggtggcccg ccagcgcgag aactgatacg ccacctcgag cagctgttcg
    20581 gccaggtcgt aggcggctcg gtacttgtcc gggctgcggt acaccgtcgc ccacacgtcc
    20641 tcgacggcat cgtcgggcac gtaggggccg gtgacgtcgc gggtgaggat gtgctcgggc
    20701 accggnagcc cggtgcgggc caggtggcgc agcacctcgt cgtagaggct gggccgctgc
    20761 aactcggcgc tcaactgcgg gaagcgcgtg aaatcggtgg gccgcaccat cgcgctcacc
    20821 cggttgccga gggtgaactc gagcagccgg tacatgtacg actgcgtgcc ggatgcctct
    20881 cccagcgtgt cgcggaacgg gaggaactcg tccaccggca tcgcgttcat gctctcccag
    20941 cagccgatga gagtgcgctg gtggcggacg gcgcgtgaca gggcgcggca ggcggcttcc
    21001 gggcggtcct cgcagatccg cgtccgggcc tgctccagct ccaggtgcac catcctgaac
    21061 agcagttcct tgacctggct cagcaggatg aactgcatct cgaagggtga gtcggtgacc
    21121 ggcagttgca gggcgtgcag agcgtccatg cgggcgtagt cgacgtacgg gttggcgtcg
    21181 ttcaccgcag cacctcccgc aagtgcgtca ccgcgtcgta cacatcggtc catgagatgt
    21241 agaggccgtt gaggcagatc cgcagcagat cggggggccg ctcgtcgacg atcacgccgc
    21301 gccgcgccag gctctcggcc accgcgaccg catccggcag gcgcagggtg acgtggttcc
    21361 cgcggcggtg cgggtcgcgc ggggtgacga tctcgacgct gtcgaggtcg gcgacgagag
    21421 cgaaaaggta gtcggcgagc cgcaggctct tggcgcgtac ggcggccatg ccggcggcct
    21481 ccagcggttc cagagccgct tccagcgcca gcagggacag gatctgcggg gtgccggtcc
    21541 gggcgcgggt gatgccgtcg gccggtacga aggaggcgct catcgcgaac gggtcggcgt
    21601 gcccgtgcca gccggtgacc gcgaaatcga gggcgtgatg gtggcgccgg gccgcgtaga
    21661 ggaaggccgg tgcgcccggg ccaccggaca gatacttgta gccgcagccg acggccaggt
    21721 ccacgcccgc ggcgtcggcc tgcaccggaa ccgccccggc cgcatggctg aggtcccaca
    21781 ccgagacgcc gccggcctgg tggatggccg tggtgagccc cggcacgtcc cacagttcgc
    21841 cggtgcggaa gtcgacggcg ccgcacagca ccgcgccgac ctggccggcg tgccgggcga
    21901 gggcgccggg caggtcgttc atcgaggtct cgaccagccg caggcccagc agccgggcga
    21961 ccgaggcggc gagatagcgg tcggtcggga agttgccggc atcggcgatc aggacccggc
    22021 gttccggtac gagccggacg gcggcggtca gagcgttgaa cagctgcacg gaggcggact
    22081 cgcccaccac cacctggccg gggccggcgc ccatcaggcg gccgatgcgg tcaccgaccc
    22141 gttcgggcgc gtcccaccac ccgtcgtccc accatccgcg gatgaggtgc tcactccact
    22201 ggcggaccgc gttcgacagt gcgatcggca ccgcggcggc cggcgggccc agcgagttgc
    22261 cgttcagtgc gagcgttccc tccgggatga gaaaatcctt cgcgaatacc gcgagcggat
    22321 cggccgaggc ttccttctcg gcccatccgc gtgtcgattc cacgagacct gccccctttt
    22381 cctggagtcc tgcgcaaggt caggcacaat gagcgctcac gatagacaga tatatcttcg
    22441 cggcagttca gggcacaact cagagcactt caaagacatt caaagaatct cgaacttatg
    22501 caggaggaat gcaagggcgt ggccagcggg aaggccctcg ccgagaatga gtaaatgacg
    22561 acaaccgaaa tggtggcccg gtgtgccgca ccccggtgcc cggtcaccgt caccgccggc
    22621 tccccgctct gccccgcctg cgtcgcccgg ctcggccggg atctgcggcg cctgccgtcg
    22681 ttgtatcagc agtgcggcga gcgccacccg cacagcaccg cgcccgcctg gcaggcgccg
    22741 ccgcgcgccg gccggcccgg cccgaccgtc ccgctgcacg cgggggccac cgacgcgcgg
    22801 cacgccatcg agaccgtgct ggcgtcctgg gccgggatga tcgcccaggc gaccggcgcg
    22861 gcgccgcccc ggcgggtcgt ggcggacctc gcccggttcc tcctggcccg gttcggcctc
    22921 ctgcagcggc acccggcagc cggcgacctg gcggcggagg tcgccgtgct ggtcgccgac
    22981 gcggagcggg tcctgcgccc ggaacgtggc cggccgctcg gtggctgcgt cgtacccggc
    23041 tgcaagggcc gtctgacggg tggcacgcag ccgcagaacc tacaggtcac gtgcgacgcc
    23101 gacgccgcac accgctggga cgggcccgag gtgctgatga tgcgtgacgg gacacccgcg
    23161 cccgcggagg cggtctggct cgacgcgagc gccatcaccg cgctgtgggg cctctcccgt
    23221 ggcagcgtgt accgcctggc gagcgagaac gggtggcggc ggcgccggcg cgacgggcgc
    23281 acccactacg ccgccgacga cgtgcgcagc acgttgggct gactcgcgtc cggaggactg
    23341 gccgtgatct gcccggccag ttccccgggc gccggcccgc cgacggtcac cgtgatctcc
    23401 gcatcgccgc tcccggctcc gagcgtgccg gacagcagcg ccggccgccc gagttcggcg
    23461 ccctgcctga tcaggaaggg ccgcggcgca tccggccgcc cctgccgatc ggcgagccag
    23521 gcgccgaacg cgagggccac cgaggcgcac gccgggtccc gcggaatggc ccagccggga
    23581 gcgaacaggc gggcttcggc actcgccgcc gggccgtccc aggcgaacag gaagatctcc
    23641 ggcaactcgt gacgggtcat cgccgggaag tcggggcggg cccggccgag tgcctcctga
    23701 cgtaccggca ccattcggaa caacggcccg aaccccgcga ggaccggctc accggccagg
    23761 tcggccgcgg ccagcccgat cgcgtcgagc accggatcgg ccggcagcga ctcgacccgc
    23821 ggtgttccgg tcgcggcgaa ttcggcacgg tcggcgccgg cgcgcagggt cagctgtctg
    23881 ccgccgcact cctgcaccac cgtgccggga cggatgtcgc cccggcggac gagggacacc
    23941 gcggtgccca ccgcggaatg gccgccgtac ggcgactcgc cagccgcggt gaacacccgg
    24001 acacggtagg tggctccgga ggtggccggc ggcagcacga acacggtctc gtcggcgcgc
    24061 agccggccgg cgatccaccg catctgctcg gtgctcaggc cgccggcgtc gtgaaccacc
    24121 gccagagggc ttccgccgcc gggctcggtg ccgaagatcc cgacgatctc gaacgagacg
    24181 gtcatccatc cccctgtagg tgagcggacg cgaagtcgag gagcacctgc tcgtccccct
    24241 cgaacggggg cgcgggacgt ggccagtgga ccacgaggtc ggtgaaaccc aggtcggcga
    24301 agagaccgga cgcgtcggcg tagctccccg tggactcgag cacaccaccg accgcgccgt
    24361 cggtcagcag cagccggcgc aggccggccg ggtcccgccc gatggcggcg cacgcctcgt
    24421 ccagcgccgc cgtctgagct ttgagcagtg gggcgacccg gtcgaagcgg tcctgttcga
    24481 agacgttggg cgggccgctg gtgacccaga tgtcggcgtg ccgggcggcc agggccattc
    24541 cccgcgggcc ggcggcggcc acggccagcg gcatggcccg gggcttgggc agcaccacgg
    24601 cgtcgtgggc ggagaaccac cgcccggtgt acgtggtccg ctcctcgtgg agcagccggt
    24661 ggagcaggct ggtgaactcg tcgaaccggt cggcgcgctc acgtggcgac agcaccgggc
    24721 cgccttgcag cgactcgtcg aagccgggcg cgccggcgcc gacgccgcag accatgcggc
    24781 ccggtgcgat gtcgtcgagg gagacgagct ccttggcgaa gctgaccggg tgccggaagt
    24841 gagggctggc caccagggtt cccagcccga tccggccggt caccgcggcg gcggcggcga
    24901 gtgtgggtac ggcggagaac cacggtctct cggcgaacca gcgccacatg aggtggtcgt
    24961 aggtccaggc gtgggcgaag ccgagccgtt cggcgagcat ccaccggttc cgtgcgcggg
    25021 gccagtggtg ctccgggagg atcaggactc cgtgccgcat caggtcccct gccgccaggc
    25081 gacctccgcg gcgtacgagg cgatggccgt cacgaccctc ccgagccgcc gctcaccgtg
    25141 ggcgaccatg gccgcggccg ccggcgtctc gtcgacggcc gcgtcgcggc ccagcgggta
    25201 gagcccgttc gcggcgaggt ccagggcgac cgcccggagc cgccgcagca actggaccgc
    25261 gaccgtcccg tcggagatcg gcgcccgtag cgtcatgaag aagttgtcgt agagcaccgc
    25321 ggtgcgctgc gacggccgca ccggggcctc gccgatgctc tcctgcaaca gggaccggcc
    25381 ctcgggaacc aatctcgcgg ccacctcctc atggatggcg cagtgggcct ccaccgcggc
    25441 ccggaccccg gccgcgctcc gctcgcgcag ccagccccgc gaccgtccgc gcagcagcga
    25501 gcggacctgg tggaagtccg gcgcccacgt gccactgaac ccgcggtgct gccggaacat
    25561 cgccgggcgg atcagcgtgg agtacaggtc gcgcgggcag gagccgctgt agagcagcat
    25621 cgcgccgtac ccgtgcacgt aggtctccag gcgttccagc acatcagggc cgggtggggc
    25681 gccgtcggtg ggatgttcgg cgagcagggc gcccatcagg cgccagagcg cgaaggtcac
    25741 ctggtgcccg gtgatccagc ggaaccagaa cagctgctcg tacgtggcgg gggaggccag
    25801 gtcgaaacgg ccggcgtcgc gggtgccgcc gtcgagcagg cgcagctcgg cacagacatg
    25861 gtccacgtcg cacggcggca cctccggcgc cacgacgccg gcgagcgcgc gtgccttgcc
    25921 cgccagcggc atggtcagcg gctccaggcc gtacgggaaa tcaccgaagt cccaagcctg
    25981 tacgcggtcg tccagcagca tgaccccggt catcggggtc cgtccggcac gtgggtgagc
    26041 tcgtactcca ggccgttggg gtcgaacagg tagacgctgc tcacgccgtc ggcgtcgacg
    26101 acgatgtcgg tcggcgggtc ggtgcgggcg aacgagaacc ggccggactc gtacagttcg
    26161 atccagtggt cccggagcac ctcgagttgc tccggctcgc tcacctgcag gcagacgtgc
    26221 tggaactgat atccctcggc gggcggcaac tgcccggtgt gcccggcccg gtcgatcagg
    26281 tgcacgcaca ggccctccat ggacacctcg acgagtctgc ggatgccggg aagacggctg
    26341 agcgtcaggt cggagaagcg gtcgagctcc caggccaccc gggcgccgaa gaactcggtg
    26401 taccaacgga cgctgttgtc caggtccgct gtctgcacgc ccacgtgatg ggcgcggagc
    26461 ggcattacca ctgtcgacat gttcctgcct cctcagggag ccggcgggcg ctccgtcaat
    26521 cgtgcgcgga aacggtagtg gcgagactgc cagaacgtat cttcgcgttc gaagagcgtc
    26581 aataggagcg gtttccaact acctcagagg attcacacgg cagatacagg agctgctggg
    26641 aactctctgt gcgctgccgt ccgcggaggt ctgtgcgcgg gcgtcgatcc tggtgagagg
    26701 cctgatgagg ttcgtggtgc ccatccggtg tccacggccg cgcatcctcg ggaatcgagg
    26761 aattgaaggt cctctcacca tgaattgaca aagctttgac gtccgccgca tcagggatcc
    26821 gttaggttcg atgcgaaagc accggagtcc gcacgggaat gcgtgtccgg cgccccgggc
    26881 gaggccggtt tcctcagacg caacgttctc tcagggaggg catatgatca gccgccgcgg
    26941 attcctcggc gcgtccgccg tcgccgtcgt gggcttcgac ctcttcggac accgctgggt
    27001 caccgcggcc gaggctgccg cggggccctc gttcgcgaag gccccgccac tcagcggtga
    27061 gctggccgtc gacgcggctg cgcgggaggc cgtcggcacc gacctcggca acatcgtcca
    27121 tcgccgcccg gccgcggtgc tccggccggg ctcggccgcc gacatcgccg cgatgatccg
    27181 gttctgttcg gcgcacggca tcccggtctc ggcacggggt caggcacaca ccacgtacgg
    27241 acagggtctg tccaccggcc tggtgatcga gatgcggcac ctgaaccgca tccaccggat
    27301 caacgaccgg ttcgccgagg tcgacgccgg catcctctgg aaggacctgg cgggcgccgc
    27361 ctacgaacag tcaccgccgc tgactccgcc ggtgctcacc ggctacaccg ggctcagcgt
    27421 gggcggcacg ctgtcggtgg gcggtgtcgg cggcatcgtc ggcggtctgc gcaccggtct
    27481 gcaggtggac cacgttcagg agctggaagt ggtcaccggc gccggcgtca tcgagcgctg
    27541 ctcccggcag cgcaagccgg acctgttcga tgcggttctc ggtggcctgg gccagtgcgc
    27601 ggtgatcacc aaggcggtga tccagctcgt cccggcccct cagcgggcac gcaacttcgt
    27661 gttgcagtac tcggacaacg ccgcgttctt ccgggacctg cgcctgctca tcgaccggac
    27721 gcaggtcgat cacgtctacg ccgagttcac ggcgccggac ccggagccgg tctacaagat
    27781 ccatgccacc gcgttctacg acgcgccggc gacgccggac gccgcggcga tcctggccgg
    27841 cgtgagcgcc gtggccgtgg tcgaggacac cccgtacctc gactacgtgc tcaccatcga
    27901 ccggctgatc gacttcctgc gggagaccga ggactgggac cgcctggtca aaccctggta
    27961 cgacgtgtgg ctttccgact ccaccatcga gcagtacctg gcggaactcg tgccgtcttt
    28021 gacacctcga gacatcgggc cgtacggggc gggtctcatc tacccgcagc gccgtgagct
    28081 caccacccgg cccgctcccc ggcgcccggc cccggacggc tcctcgttcg tctacgtggt
    28141 ggacgtcaac acggtctcca gcgcccccgg ccccgacccg gcgttcagcg cggagatgct
    28201 ggagcgcaac aagcggctct acgctcgggc caggcgatcc tacggcgccg tgctgtaccc
    28261 gatcggctcg gtgcccttca ccgagcagga ctggcgcgac cactacggca gcgcgtggcc
    28321 ggccttccgt gccgcgaaac gccggtacga ccccgctgga gtgctcacct ccggcccggg
    28381 catcttccgc cgcagctgac caggccgacg gcgggccgga cccggcggcg ctcgctcgag
    28441 aacgccgcgc cgccgggccc ggccgcttcg actatccgag ggtgatgaca gttgtcaggt
    28501 gaggaccatc agcggcaggg gctcctgcac gccgcgctcg accgcctccg ctgccgcctg
    28561 ccgtcgctgg ccgccgccac ggtgcaggcc gtccgccggc acggcgatgc cccgccggcg
    28621 cccgccgccg acggggcgtt gcgcacgatc gtccaccacg cggcgctctg ggtgctcgaa
    28681 gccgtcgacg accgtaccga cccggcgcac atcggcgaag ccggcctgct gaaccgcacc
    28741 caccacagcc tcaccgcccc gctggtcagc caggcctgca acgacatgtg ccggcgcacc
    28801 tggcaggccc tcgtgcagga ggcgacggcg gaggaggggc agctgctgct ggaacgctcg
    28861 gcgcgctacc tcgccgccag caccgaactc gtcgagcatg tgctcaccga acagagcgcc
    28921 gcagccggat ccgagacacg cctgcgcgag atggccaccc ggctgctcaa cggcgaacgg
    28981 ccgcccgcgt cgctgtcggc cgagggcggg acggccgaca cgtacgcggt gctggccgtc
    29041 cccacccagc ggcccggcga gatcgccggc atcgcggcac ggcaccactg gctcagcgcc
    29101 gagcagcccg gagccgtcac cgtgctggtg cccgtcggtg gccccggccg gcgtgcggac
    29161 ggcagggccc gcgcccggca cgccttccac gcgctgtgcc cgcaacaccc cgtcggcctc
    29221 ggcctgcccg ccgatgtcga gggcatcccg gcggcggtgg ccgacgcctg ggaggccgtc
    29281 gcgacgctgc gccggctcgg ccggcacgaa ccgggcctct tccagctcga cgacgtgctg
    29341 ctggaggcga tgctctgccg cgcgcccgag ctggccgccc ggctggccgg ccgactgcgg
    29401 ccggtgaccc gatgccagcc gtatctgctg gacacgctgg ccgccttcct ggacaacgac
    29461 ggcgatcggc gggagctggc acggcagctg tacatccacc cgaacacgct caaccaccgc
    29521 ctccggcgcg tctccgagct caccgggctg tcgctggcca acgccggtga cctctgcctg
    29581 ctgaaggcgg cgctcaccgc gtggcaggtg acgaatgcgg cggccggcgc gggcaccggc
    29641 cgccccgcct tccgggcggc ctgaaccgcc gcggtcagcg gacgatcccg tacgcctgct
    29701 gaccgcgctg actcgccgcc gcgaacacca ggccgtcgcc ggtgtggccg gtggcgcaca
    29761 ccttgcccag cgaccgggcc gccacctgct ggagccgatg tccccgccct tccagggcgg
    29821 cgatcgtctc ggcggggagg ccctcctcca cgacgacgac cggcggcggc gtctgccggg
    29881 gcatgaacga cgagggcacg tgaccggtgt ggaaggtcag cgcctcgacc gcggcctgcg
    29941 gcgtcatcgc gaaatcgatg ctgttgagcg cgaagttgag ggtccactgg tcctgctggt
    30001 cgccgccggg cgtgccgaac gccagcagcg gctcgcccga gccgtcctgc acgatggtgg
    30061 ggctgagcgt cgtccgcggt cgtttgccgg gcgccagcga gttcgggtgg ccctccacga
    30121 gccaggccat ctgcccgcgg gtgctcagcg cgaatcccag accggggact gccggggaac
    30181 tgctgaacca gccgccgctc tgcgtggcca ccaccatgtt gccgtcccgg tcggtggcgc
    30241 tgatgcaggt ggtgtcacga ttctgcgagg tccgccgcac gaccgccggg atgccgtggg
    30301 cgagctggtt catccactcc ggctccagcg gagccgtctc atcgggcagt ggcggcagcc
    30361 acggctcgcg cccgagcgga gacccgggtc gcagaccggc cgcggcccgg tccccgatca
    30421 gggctcgccg ctgctcggtg tagccgggcg acagcagctc ccgcagtggc acgtcgacgt
    30481 ggccggggtc gccgtaccac gcctcccggt cgccgaaggc gagtttggca gcctcgacga
    30541 ccgtgtggat gtgatcggga ccgaggtgcc gcatcgagcc cagatcgaag ccctccaaca
    30601 gggcgagctg ctgcaggaac accggtccct gcgtccacgg gcccggcttg tggatcaggc
    30661 ggccccggta gccggcggtg acgggcgcct cgacggcagg gcgccacgcc gccaggtcct
    30721 caccgcgaag caggccccgg tgccgtttgc cggtcgcgtc gagcatctct gccgagcaca
    30781 tgaacgcatc gatggcctcg gcgacgaagc cctcgtagaa gacgtccacg gcggcctcga
    30841 tctcggactc gcgtgcccgg cccggagcgg acgcctcccg cacgatacgg cggaacgtcg
    30901 cggccaggtc gggattgcgg acgagcgatc cggcgcgagg cgcggcgcca cggtcgaggt
    30961 agatccggcc cgtctcggtc cactcctcgc ggaacagggg tgtgagagcc tcgatgatcg
    31021 cggccgccgg ggccagcagc gggtatccgc cctcggcata cccgatggcg ggttccagca
    31081 cgtcggccag ccgcagccgg ccgtggcgga gcagcaccgt catccatgcg ccgaaggcgc
    31141 cggggacgca cgccgccagc aggcccgacc ccgggacgta gccgaggccg aggcgccgga
    31201 acgtctcgat ggaggcccgg cgcggcatcg gtccctgccc ggccaccacc gtcacctcgc
    31261 ccgaggaggc gtcgtgcacc atgatcggcg cttccgcggc cggcccgttg acgtgtggct
    31321 ccaccacctg gatcacgaag gccgcggcaa cggcggcgtc gaaggcgttg ccgccccgat
    31381 cgaacatcgc cgcgcccgcc gcggaggcca gccagtgcgt ggacgacacc gctccatacg
    31441 tgccgtgcag ttcgggacgc gacagcatga tcttccctcc gctcgacgga cgctgccagc
    31501 cgagcgtcgc acagctgtgg acggaccggc cgaactcggt ggcccggcac aacggtgttg
    31561 gtgacggcca cagtgtcccg gcggatcgga gccgacgacg ggcgccgggc ccgagaatca
    31621 ccggcaggga tcgccgaaga ggaggagcat cgtgcatacc gatgcggttg atcagctcgt
    31681 cgagctcagg acccagcctc aattgcggga atggcaggac ttccagctgt ccgggatgcc
    31741 gcagctgatc agtgcgatgc acctgtgcca ggccgtgcac gcgctggccg agacgggtct
    31801 gctcgccgaa ctgcgggccg ggctgagccg ggagcacatc gattcgctgt ccggtctcga
    31861 cccggagctg gtccggggct tcctgtccta cctggtggtc cgcggcgtgg tcgacgacct
    31921 gccggacggc taccggctga gccggcgcgg cgagctgctg accaccgatg tgtccctcgc
    31981 ccgcctgggt gtgtacgccg gggcatacgg cgccgtgacg gcccggacag gcgatctgct
    32041 caccggcaga gcgcgctacg gcgtggacgt ccaccgcgac ggcggcgccc tcggcaggca
    32101 ctgtgccacc ctgttcgagg tcttccacag cgagacgatc agaaccgcga ccgagaggcg
    32161 cggcatccgt acgatgctcg atgccggctg cggggccggc cagctgctca tcgacgcgtg
    32221 caggcgcgat gagagactga ccggcatcgg cctcgacaac tcacccgagg ccatcgcggt
    32281 cgccgagaag ctggctcgcg aacacggcgt cgccgatcgc atccagttct tcgtcgccga
    32341 cgcgttcgaa cccgagacgt ggccggaagc ctgccgcgac gccgacgcca tgtgcatcgt
    32401 cagcgccctg cacgagcact tccgccacgg cgaggacgcg gtgatcgaac tgctgcgccg
    32461 ttatgccggc gcgcttcccg ccctcgagat gctgctggtc ggcgagccgg agctgctgta
    32521 cgaggacagg gagaaccacg acgacttcct gctcgtgcac gtcctgaccg gacaggggct
    32581 gcccagggac cgcaacgcct ggctgccggt gttcgagaag gccgggctgc ggtgcgagca
    32641 catctacatg cggccgggtg cgggcccgag gttgtgcttc tacgacctga acccgcgcac
    32701 ccagcgccat tga
//
