BGC0000442: terrequinone A biosynthetic gene cluster from Aspergillus nidulans FGSC A4
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Location: 732,113 - 741,871 nt. (total: 9,759 nt).
This entry is originally from NCBI GenBank BN001305.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000442
Short description terrequinone A biosynthetic gene cluster from Aspergillus nidulans FGSC A4
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
BN001305.1
732113 - 741871
via Knock-out studies, Heterologous expression, Gene expression correlated with compound production
Compounds
  • terrequinone A
Species Aspergillus nidulans FGSC A4 [taxonomy]
References
Chemical products information
terrequinone A Evidence: NMR, Mass spectrometry
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C32H30N2O3
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ANIA_08513
  • CBF80711.1
 732113 - 735025 (-) TdiA [Source:UniProtKB/TrEMBL;Acc:A7XRY0]
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    • ANIA_08514
    • CBF80712.1
    		 735415 - 736807 (+) Putative uncharacterized proteinTdiB; [Source:UniProtKB/TrEMBL;Acc:Q5AT66]
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      • ANIA_08518
      • CBF80714.1
      		 737458 - 738525 (+) Putative uncharacterized proteinTdiC; [Source:UniProtKB/TrEMBL;Acc:Q5AT62]
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        • ANIA_08516
        • CBF80716.1
        		 738742 - 740415 (+) L-tryptophan:phenylpyruvate aminotransferase (Eurofung)
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          • ANIA_08520
          • CBF80718.1
          		 740487 - 741871 (-) conserved hypothetical protein
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            Biosynthesis information

            Biosynthetic modules

            Name
            1
            Type
            nrps-type1
            Genes
            ANIA_08513
            Substrates
            indole-3-pyruvic acid (evidence: Activity assay)
            Integrated Monomers
            Domains
            adenylation
            Annotation changelog

            Entry version: 4

            Date
            Changes
            Submitters
            Reviewers
            2022-10-07
            Update chemical activity to schema version 2.11
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 3

            Date
            Changes
            Submitters
            Reviewers
            2022-09-15
            Corrected NRP module activity
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            2022-09-15
            Corrected gene identifiers
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 2

            Date
            Changes
            Submitters
            Reviewers
            2019-10-16
            Migrated from v1.4
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            2019-10-16
            Updated compound(s) information (NPAtlas curation)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 1

            Date
            Changes
            Submitters
            Reviewers
            2015-06-12
            Submitted
            • (ID: IZ42H4KADWMZS2AQ3USUWI6C)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            Detailed domain annotation
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