BGC0000442 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000442 (Aspergillus nidulans FGSC A4)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	NRPS-like,indole	1	42,913	High	terrequinone A	NRPS:Type I

BGC0000442 - Region 1 - NRPS-like,indole

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Location: 1 - 42,913 nt. (total: 42,913 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX) and not alpha_am_amid)
indole: (indsynth or dmat or indole_PTase)

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 42,914
Label		BGC0000442

Tailoring functions

Transferases: aminotransferase

ANIA_08516: aminotransferase

smcogs: SMCOG1019: aminotransferase

Ligases: ligase

ANIA_08513: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000442.5	1.88	NRPS	terrequinone A	Aspergillus nidulans FGSC A4
BGC0002274.2	0.91	NRPS	aspulvinone H, aspulvinone B1	Aspergillus terreus NIH2624
BGC0002193.2	0.89	other (other)	phenguignardic acid	Aspergillus terreus NIH2624
BGC0002277.2	0.87	NRPS	atromentin	Suillus grevillei
BGC0001712.3	0.72	other (other)	ochrindole A	Aspergillus steynii IBT 23096
BGC0002271.2	0.49	NRPS	asterriquinone CT5	Aspergillus terreus NIH2624
BGC0001668.4	0.40	NRPS	microperfuranone	Aspergillus nidulans FGSC A4
BGC0002348.2	0.37	NRPS	aspulvinone E	Aspergillus terreus NIH2624
BGC0002529.3	0.20	NRPS	aminochelin, azotochelin, protochelin	Azotobacter vinelandii CA
BGC0001260.3	0.20	terpene	terpendole E	Tolypocladium album

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000442.5	0.98	NRPS	terrequinone A	Aspergillus nidulans FGSC A4
BGC0002274.2	0.76	NRPS	aspulvinone H, aspulvinone B1	Aspergillus terreus NIH2624
BGC0002193.2	0.75	other (other)	phenguignardic acid	Aspergillus terreus NIH2624
BGC0002277.2	0.74	NRPS	atromentin	Suillus grevillei
BGC0001712.3	0.69	other (other)	ochrindole A	Aspergillus steynii IBT 23096
BGC0002271.2	0.58	NRPS	asterriquinone CT5	Aspergillus terreus NIH2624
BGC0001668.4	0.52	NRPS	microperfuranone	Aspergillus nidulans FGSC A4
BGC0002348.2	0.50	NRPS	aspulvinone E	Aspergillus terreus NIH2624
BGC0002529.3	0.36	NRPS	aminochelin, azotochelin, protochelin	Azotobacter vinelandii CA
BGC0001260.3	0.36	terpene	terpendole E	Tolypocladium album

Similar known clusters from MIBiG 4.0

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Detailed domain annotation

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 42913:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ANIA_08513: X

AMP-binding (32..462): X

nrpys: Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: IFVFYGSAGK
Nearest Stachelhaus code(s):: 4-ohPpa IAAFLGAAGK (62% 8Å match)
Stachelhaus code match:: 60% (weak)

Link to PARAS substrate predictor